{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,20]],"date-time":"2026-09-20T23:09:03Z","timestamp":1789945743816,"version":"4.0.1"},"reference-count":39,"publisher":"Oxford University Press (OUP)","issue":"3","license":[{"start":{"date-parts":[[2019,2,11]],"date-time":"2019-02-11T00:00:00Z","timestamp":1549843200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"funder":[{"name":"University of Lagos, Nigeria"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2019,4,16]]},"DOI":"10.1093\/jme\/tjz006","type":"journal-article","created":{"date-parts":[[2019,2,11]],"date-time":"2019-02-11T08:20:17Z","timestamp":1549873217000},"page":"817-821","source":"Crossref","is-referenced-by-count":23,"title":["Cytochrome P450 Mono-Oxygenase and Resistance Phenotype in DDT and Deltamethrin-Resistant Anopheles gambiae (Diptera: Culicidae) and Culex quinquefasciatus in Kosofe, Lagos, Nigeria"],"prefix":"10.1093","volume":"56","author":[{"given":"Ifeoluwa K","family":"Fagbohun","sequence":"first","affiliation":[{"name":"Department of Zoology, University of Lagos, Lagos, Nigeria"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tolulope A","family":"Oyeniyi","sequence":"additional","affiliation":[{"name":"Vector Research Laboratory, Nigeria Institute of Medical Research, Lagos, Nigeria"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Taiwo E","family":"Idowu","sequence":"additional","affiliation":[{"name":"Department of Zoology, University of Lagos, Lagos, Nigeria"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Olubunmi A","family":"Otubanjo","sequence":"additional","affiliation":[{"name":"Department of Zoology, University of Lagos, Lagos, Nigeria"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Samson T","family":"Awolola","sequence":"additional","affiliation":[{"name":"Vector Research Laboratory, Nigeria Institute of Medical Research, Lagos, Nigeria"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[2019,2,11]]},"reference":[{"key":"2019041618330493100_CIT0001","first-page":"1","article-title":"Dynamics of insecticide resistance and effect of synergists piperonyl butoxide (PBO), S. S . S- tributylphosphorotrithioate (DEF) and ethacrynic acid (ETAA or EA) on permethrin, deltamethrin and dichlorodiphenyltrichloroethane (DDT) resistance i","volume":"6","author":"A\u00efzoun","year":"2014","journal-title":"J. Parasitol. Vector Biol"},{"key":"2019041618330493100_CIT0002","first-page":"181","article-title":"Dynamics of knockdown pyrethroid insecticide resistance alleles in a field population of Anopheles gambiae s.s. in southwestern Nigeria","volume":"44","author":"Awolola","year":"2007","journal-title":"J. Vector Borne Dis"},{"key":"2019041618330493100_CIT0003","doi-asserted-by":"crossref","first-page":"1139","DOI":"10.1016\/j.trstmh.2008.08.021","article-title":"Evidence of multiple pyrethroid resistance mechanisms in the malaria vector Anopheles gambiae sensu stricto from Nigeria","volume":"103","author":"Awolola","year":"2009","journal-title":"Trans. R. Soc. Trop. Med. Hyg"},{"key":"2019041618330493100_CIT0004","first-page":"93","article-title":"The challenge of water supply in urban lagos under increasing climatic variability","volume":"2","author":"Ayeni","year":"2014","journal-title":"J. Geogr. Issues"},{"key":"2019041618330493100_CIT0005","doi-asserted-by":"crossref","first-page":"605","DOI":"10.3201\/eid0404.980410","article-title":"Insecticide resistance and vector control","volume":"4","author":"Brogdon","year":"1998","journal-title":"Emerg. Infect. Dis"},{"key":"2019041618330493100_CIT0006","doi-asserted-by":"crossref","first-page":"108","DOI":"10.1016\/j.actatropica.2013.10.020","article-title":"Synergist bioassays: a simple method for initial metabolic resistance investigation of field Anopheles gambiae s.l. populations","volume":"130","author":"Choua\u00efbou","year":"2014","journal-title":"Acta Trop"},{"key":"2019041618330493100_CIT0007","doi-asserted-by":"crossref","first-page":"37","DOI":"10.4269\/ajtmh.1987.37.37","article-title":"A ribosomal RNA gene probe differentiates member species of the Anopheles gambiae complex","volume":"37","author":"Collins","year":"1987","journal-title":"Am. J. Trop. Med. Hyg"},{"key":"2019041618330493100_CIT0008","doi-asserted-by":"crossref","first-page":"580","DOI":"10.5772\/56117","article-title":"Distribution, mechanisms, impact and management of insecticide resistance in malaria vectors: a pragmatic review,","volume-title":"Anopheles mosquitoes\u2014New insights into malaria vectors","author":"Corbel","year":"2013"},{"key":"2019041618330493100_CIT0009","doi-asserted-by":"crossref","first-page":"207","DOI":"10.1016\/j.actatropica.2007.01.005","article-title":"Multiple insecticide resistance mechanisms in Anopheles gambiae and Culex quinquefasciatus from Benin, West Africa","volume":"101","author":"Corbel","year":"2007","journal-title":"Acta Trop"},{"key":"2019041618330493100_CIT0010","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1186\/s12936-017-1960-3","article-title":"Evaluation of piperonyl butoxide in enhancing the efficacy of pyrethroid insecticides against resistant Anopheles gambiae s.l. in Ghana","volume":"16","author":"Dadzie","year":"2017","journal-title":"Malar. J"},{"key":"2019041618330493100_CIT0011","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1371\/journal.pone.0199615","article-title":"Multiple insecticide resistance in Culex quinquefasciatus populations from Guadeloupe (French West Indies) and associated mechanisms","volume":"13","author":"Delannay","year":"2018","journal-title":"PLoS One"},{"key":"2019041618330493100_CIT0012","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1186\/s12936-017-1767-2","article-title":"Effects of community-level bed net coverage on malaria morbidity in Lilongwe, Malawi","volume":"16","author":"Escamilla","year":"2017","journal-title":"Malar. J"},{"key":"2019041618330493100_CIT0013","doi-asserted-by":"crossref","first-page":"19","DOI":"10.1002\/tox.20386","article-title":"Synergist efficacy of piperonyl butoxide with deltamethrin as pyrethroid insecticide on Culex tritaeniorhynchus (Diptera: Culicidae) and other mosquito species","volume":"24","author":"Fakoorziba","year":"2009","journal-title":"Environ. Toxicol"},{"key":"2019041618330493100_CIT0014","first-page":"1","article-title":"Piperonyl butoxide (PBO) combined with pyrethroids in long-lasting insecticidal nets (LLINs) to prevent malaria in Africa","volume":"8","author":"Gleave","year":"2017","journal-title":"Cochrane Database Syst. Rev"},{"key":"2019041618330493100_CIT0015","doi-asserted-by":"crossref","first-page":"371","DOI":"10.1146\/annurev.ento.45.1.371","article-title":"Insecticide resistance in insect vectors of human disease","volume":"45","author":"Hemingway","year":"2000","journal-title":"Annu. Rev. Entomol"},{"key":"2019041618330493100_CIT0016","doi-asserted-by":"crossref","first-page":"653","DOI":"10.1016\/j.ibmb.2004.03.018","article-title":"The molecular basis of insecticide resistance in mosquitoes","volume":"34","author":"Hemingway","year":"2004","journal-title":"Insect Biochem. Mol. Biol"},{"key":"2019041618330493100_CIT0017","doi-asserted-by":"crossref","first-page":"23","DOI":"10.1016\/j.ibmb.2015.10.015","article-title":"The cytochrome P450 CYP6P4 is responsible for the high pyrethroid resistance in knockdown resistance-free Anopheles arabiensis","volume":"68","author":"Ibrahim","year":"2016","journal-title":"Insect Biochem. Mol. Biol"},{"key":"2019041618330493100_CIT0018","doi-asserted-by":"crossref","first-page":"78","DOI":"10.1186\/1756-3305-5-78","article-title":"Insecticide resistance in Culex quinquefasciatus from Zanzibar: implications for vector control programmes","volume":"5","author":"Jones","year":"2012","journal-title":"Parasit. Vectors"},{"key":"2019041618330493100_CIT0019","doi-asserted-by":"crossref","first-page":"537","DOI":"10.1146\/annurev-ento-010814-020828","article-title":"Insecticide resistance in mosquitoes: impact, mechanisms, and research directions","volume":"60","author":"Liu","year":"2015","journal-title":"Annu. Rev. Entomol"},{"key":"2019041618330493100_CIT0020","doi-asserted-by":"crossref","first-page":"179","DOI":"10.1046\/j.1365-2583.1998.72062.x","article-title":"Molecular characterization of pyrethroid knockdown resistance (kdr) in the major malaria vector Anopheles gambiae s.s","volume":"7","author":"Martinez-Torres","year":"1998","journal-title":"Insect Mol. Biol"},{"key":"2019041618330493100_CIT0021","doi-asserted-by":"crossref","first-page":"407","DOI":"10.1016\/j.ibmb.2012.10.006","article-title":"Impact of environment on mosquito response to pyrethroid insecticides: facts, evidences and prospects","volume":"43","author":"Nkya","year":"2013","journal-title":"Insect Biochem. Mol. Biol"},{"key":"2019041618330493100_CIT0022","first-page":"114","article-title":"High level of DDT resistance in the Malaria Mosquito\u202f: anopheles gambiae S. L . From Rural, semi urban and urban communities in nigeria","volume":"9","author":"Oduola","year":"2010","journal-title":"J. Rural Trop. Public Heal"},{"key":"2019041618330493100_CIT0023","first-page":"164","article-title":"Species composition and temporal distribution of mosquito populations in Ibadan, Southwestern Nigeria","volume":"2","author":"Okorie","year":"2014","journal-title":"J. Entomol. Zool. Stud"},{"key":"2019041618330493100_CIT0024","doi-asserted-by":"crossref","first-page":"1577","DOI":"10.1016\/S0140-6736(18)30427-6","article-title":"Effectiveness of a long-lasting piperonyl butoxide-treated insecticidal net and indoor residual spray interventions, separately and together, against malaria transmitted by pyrethroid-resistant mosquitoes: a cluster, randomised controlled, two-by-two factorial design trial","volume":"391","author":"Protopopoff","year":"2018","journal-title":"Lancet"},{"key":"2019041618330493100_CIT0025","doi-asserted-by":"crossref","first-page":"68","DOI":"10.1016\/j.pestbp.2014.12.018","article-title":"Pyrethroid resistance in Culex pipiens mosquitoes","volume":"120","author":"Scott","year":"2015","journal-title":"Pestic. Biochem. Physiol"},{"key":"2019041618330493100_CIT0026","doi-asserted-by":"crossref","first-page":"339","DOI":"10.4269\/ajtmh.2004.70.339","article-title":"Rapid assays for identification of members of the Culex (Culex) pipiens complex, their hybrids, and other sibling species (Diptera: Culicidae)","volume":"70","author":"Smith","year":"2004","journal-title":"Am. J. Trop. Med. Hyg"},{"key":"2019041618330493100_CIT0027","doi-asserted-by":"crossref","first-page":"46","DOI":"10.1186\/s40249-015-0076-7","article-title":"Insecticide resistance in malaria-transmitting mosquitoes in Zimbabwe: a review","volume":"4","author":"Soko","year":"2015","journal-title":"Infect. Dis. Poverty"},{"key":"2019041618330493100_CIT0028","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1186\/s13071-018-2625-y","article-title":"Insecticide resistance and target site mutations (G119S ace-1 and L1014F kdr) of Culex pipiens in Morocco","volume":"11","author":"Tmimi","year":"2018","journal-title":"Parasites and Vectors"},{"key":"2019041618330493100_CIT0029","first-page":"159","article-title":"Efficacy of piperonyl butoxide (PBO) as a synergist with deltamethrin on five species of mosquitoes","volume":"39","author":"Vijayan","year":"2007","journal-title":"J. Commun. Dis"},{"key":"2019041618330493100_CIT0030","doi-asserted-by":"crossref","first-page":"241","DOI":"10.1016\/j.sjbs.2013.02.001","article-title":"Development of permethrin resistance in Culex quinquefasciatus Say in Kuala Lumpur, Malaysia","volume":"20","author":"Wan-Norafikah","year":"2013","journal-title":"Saudi J. Biol. Sci"},{"key":"2019041618330493100_CIT0031","first-page":"1","article-title":"Malaria vector control and personal protection","volume":"936","author":"WHO","year":"2006","journal-title":"WHO Tech. Rep. Ser"},{"key":"2019041618330493100_CIT0032","volume-title":"Insecticide-treated mosquito nets: a WHO position statement","author":"WHO","year":"2007"},{"key":"2019041618330493100_CIT0033","volume-title":"World Malaria Report 2011","author":"WHO","year":"2011"},{"key":"2019041618330493100_CIT0034","volume-title":"Global technical strategy for malaria 2016\u20132030","author":"WHO","year":"2015"},{"key":"2019041618330493100_CIT0035","volume-title":"Test procedures for insecticide resistance monitoring in malaria vector mosquitoes","author":"WHO","year":"2016"},{"key":"2019041618330493100_CIT0036","volume-title":"Global vector control response 2017\u20132030","author":"WHO","year":"2017"},{"key":"2019041618330493100_CIT0037","volume-title":"World Malaria Report 2017","author":"WHO","year":"2017"},{"key":"2019041618330493100_CIT0038","volume-title":"Malaria surveillance, monitoring & evaluation: a reference manual","author":"WHO","year":"2018"},{"key":"2019041618330493100_CIT0039","doi-asserted-by":"crossref","first-page":"4","DOI":"10.1186\/s13071-015-0638-3","article-title":"Insecticide resistance status in Culex quinquefasciatus in Benin","volume":"8","author":"Yadoul\u00e9ton","year":"2015","journal-title":"Parasites and Vectors"}],"container-title":["Journal of Medical Entomology"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/academic.oup.com\/jme\/article-pdf\/56\/3\/817\/28463177\/tjz006.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,4,16]],"date-time":"2019-04-16T22:37:42Z","timestamp":1555454262000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/jme\/article\/56\/3\/817\/5314833"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,2,11]]},"references-count":39,"journal-issue":{"issue":"3","published-online":{"date-parts":[[2019,2,11]]},"published-print":{"date-parts":[[2019,4,16]]}},"URL":"https:\/\/doi.org\/10.1093\/jme\/tjz006","relation":{},"ISSN":["0022-2585","1938-2928"],"issn-type":[{"value":"0022-2585","type":"print"},{"value":"1938-2928","type":"electronic"}],"subject":[],"published-other":{"date-parts":[[2019,5]]},"published":{"date-parts":[[2019,2,11]]}}}