{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,23]],"date-time":"2026-10-23T12:44:36Z","timestamp":1792759476220,"version":"4.5.0"},"reference-count":30,"publisher":"Oxford University Press (OUP)","issue":"5","license":[{"start":{"date-parts":[[2019,5,23]],"date-time":"2019-05-23T00:00:00Z","timestamp":1558569600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/journals\/pages\/open_access\/funder_policies\/chorus\/standard_publication_model"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2019,9,3]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>This study records the clinical findings in nine hunting dogs showing systemic illness associated with trombiculids and identifies the mite species involved. In fall, coinciding with the seasonality of mites, all dogs were infested with mites and had been in the risk area (Sierra Cebollera Natural Park, La Rioja, Spain) a few hours before the onset of symptoms. The symptoms included vomiting, anorexia, weakness and lethargy, diarrhea, and even stupor. The clinical picture was fast-acting and potentially fatal. The infestations varied from low to severe. Molecular analysis of mites that fed on the dogs confirmed that they were larvae of Neotrombicula inopinata (Oudemans, Acari, Trombiculidae). This is the first time that N. inopinata has been identified as feeding on dogs and implicated in canine systemic illness associated with trombiculids. In contrast to other chiggers, N. inopinata does not seem to cause dermatitis. Likewise, the clinical and epidemiological similarity between the clinical symptoms we describe herein and the occurrence of seasonal canine illness (SCI) led us to suspect that this illness may be caused by infestation with these mites. The condition could be the consequence of severe infestation from large numbers of feeding mites, especially N. inopinata. Whether or not the cases were due to a severe allergic host response to salivary proteins or the result of the transmission of a new or emerging trombiculid-borne pathogen is not known.<\/jats:p>","DOI":"10.1093\/jme\/tjz071","type":"journal-article","created":{"date-parts":[[2019,5,23]],"date-time":"2019-05-23T13:40:42Z","timestamp":1558618842000},"page":"1389-1394","source":"Crossref","is-referenced-by-count":9,"title":["Severe Trombiculiasis in Hunting Dogs Infested With Neotrombicula inopinata (Acari: Trombiculidae)"],"prefix":"10.1093","volume":"56","author":[{"given":"M","family":"Areso Apestegu\u00eda","sequence":"first","affiliation":[{"name":"Cl\u00ednica Veterinaria Areso, C\/ Vencerol, Tudela, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J B","family":"Areso Portell","sequence":"additional","affiliation":[{"name":"Cl\u00ednica Veterinaria Areso, C\/ Vencerol, Tudela, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"N","family":"Halaihel Kassab","sequence":"additional","affiliation":[{"name":"Departamento de Patolog\u00eda Animal, Instituto Agroalimentario de Arag\u00f3n - IA2 (Universidad de Zaragoza - CITA), Facultad de Veterinaria, Zaragoza, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1417-272X","authenticated-orcid":false,"given":"M J","family":"Gracia Salinas","sequence":"additional","affiliation":[{"name":"Departamento de Patolog\u00eda Animal, Instituto Agroalimentario de Arag\u00f3n - IA2 (Universidad de Zaragoza - CITA), Facultad de Veterinaria, Zaragoza, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[2019,5,23]]},"reference":[{"key":"2019091012103078700_CIT0001","first-page":"427","article-title":"Les ectoparasites du chat","volume":"34","author":"Beugnet","year":"1999","journal-title":"Prat. Med. Chir. Anim"},{"key":"2019091012103078700_CIT0002","doi-asserted-by":"crossref","first-page":"1482","DOI":"10.1645\/0022-3395(2001)087[1482:MDOEPG]2.0.CO;2","article-title":"Molecular detection of Ehrlichia phagocytophila genogroup organisms in larvae of Neotrombicula autumnalis (Acari: Trombiculidae) captured in Spain","volume":"87","author":"Fern\u00e1ndez-Soto","year":"2001","journal-title":"J. Parasitol"},{"key":"2019091012103078700_CIT0003","doi-asserted-by":"crossref","first-page":"955","DOI":"10.1016\/j.ijpara.2014.08.003","article-title":"Parasitic mites of medical and veterinary importance\u2013is there a common research agenda?","volume":"44","author":"Fischer","year":"2014","journal-title":"Int. J. Parasitol"},{"key":"2019091012103078700_CIT0004","doi-asserted-by":"crossref","first-page":"67","DOI":"10.1111\/j.1365-3164.2007.00560.x","article-title":"Straelensiosis in a dog in Spain","volume":"18","author":"Font","year":"2007","journal-title":"Vet. Dermatol"},{"key":"2019091012103078700_CIT0005","doi-asserted-by":"crossref","first-page":"294","DOI":"10.1016\/j.vetpar.2012.06.012","article-title":"Trombiculiasis caused by chigger mites Eutrombicula (Acari: Trombiculidae) in Peruvian alpacas","volume":"190","author":"Gomez-Puerta","year":"2012","journal-title":"Vet. Parasitol"},{"key":"2019091012103078700_CIT0006","volume-title":"Infectious diseases of the dog and cat","author":"Greene","year":"2006","edition":"3"},{"key":"2019091012103078700_CIT0007","first-page":"3","article-title":"La straelensiose du chien: une dermatose parasitaire de description r\u00e9cente en France","volume":"46","author":"Guagu\u00e8re","year":"2011","journal-title":"Prat. Med. Chir. Anim"},{"key":"2019091012103078700_CIT0008","first-page":"495","article-title":"Trombiculiasis: clinical contribution","volume":"15","author":"Guarneri","year":"2005","journal-title":"Eur. J. Dermatol"},{"key":"2019091012103078700_CIT0009","doi-asserted-by":"crossref","first-page":"275","DOI":"10.1111\/jsap.12036","article-title":"Mushroom toxicosis in dogs in general practice causing gastroenteritis, ptyalism and elevated serum lipase activity","volume":"54","author":"Hall","year":"2013","journal-title":"J. Small Anim. Pract"},{"issue":"s1","key":"2019091012103078700_CIT0010","first-page":"348","article-title":"A seasonal outbreak of human parasitation by chiggers in La Rioja (Northern Spain)","volume":"7","author":"Jim\u00e9nez","year":"2001","journal-title":"J. Clin. Microbiol"},{"key":"2019091012103078700_CIT0011","doi-asserted-by":"crossref","first-page":"93","DOI":"10.1023\/B:APPA.0000029975.92510.90","article-title":"Neotrombicula autumnalis (Acari, Trombiculidae) as a vector for Borrelia burgdorferi sensu lato?","volume":"33","author":"Kampen","year":"2004","journal-title":"Exp. Appl. Acarol"},{"key":"2019091012103078700_CIT0012","volume-title":"A manual of acarology","author":"Krantz","year":"2009","edition":"3"},{"key":"2019091012103078700_CIT0013","doi-asserted-by":"crossref","first-page":"205","DOI":"10.1136\/vr.150.7.205","article-title":"Straelensiosis in dogs: a newly described nodular dermatitis induced by Straelensia cynotis","volume":"150","author":"Le Net","year":"2002","journal-title":"Vet. Rec"},{"key":"2019091012103078700_CIT0014","doi-asserted-by":"crossref","first-page":"307","DOI":"10.1007\/s10493-008-9150-1","article-title":"Larvae of chigger mites Neotrombicula spp. (Acari: Trombiculidae) exhibited Borrelia but no Anaplasma infections: a field study including birds from the Czech Carpathians as hosts of chiggers","volume":"44","author":"Literak","year":"2008","journal-title":"Exp. Appl. Acarol"},{"key":"2019091012103078700_CIT0015","doi-asserted-by":"crossref","first-page":"406","DOI":"10.1136\/vr.e6979","article-title":"Canine trombiculiasis and seasonal canine illness","volume":"20","author":"McGarry","year":"2012","journal-title":"Vet. Rec"},{"key":"2019091012103078700_CIT0016","doi-asserted-by":"crossref","first-page":"2465","DOI":"10.1007\/s00436-015-4443-x","article-title":"First detections of Rickettsia helvetica and R. monacensis in ectoparasitic mites (Laelapidae and Trombiculidae) infesting rodents in south-western Slovakia","volume":"114","author":"Mit\u2019kov\u00e1","year":"2015","journal-title":"Parasitol. Res"},{"key":"2019091012103078700_CIT0017","doi-asserted-by":"crossref","first-page":"449","DOI":"10.1016\/B978-012510451-7\/50025-6","article-title":"Mites (Acari),","volume-title":"Medical and veterinary entomology","author":"Mullen","year":"2002"},{"key":"2019091012103078700_CIT0018","doi-asserted-by":"crossref","first-page":"2669","DOI":"10.1128\/JCM.00366-06","article-title":"Cluster of cases of human Rickettsia felis infection from Southern Europe (Spain) diagnosed by PCR","volume":"44","author":"Oteo","year":"2006","journal-title":"J. Clin. Microbiol"},{"key":"2019091012103078700_CIT0019","doi-asserted-by":"crossref","first-page":"35","DOI":"10.1111\/j.1365-3164.2008.00722.x","article-title":"Clinical, histopathological and epidemiological study of canine straelensiosis in the Iberian Peninsula (2003-2007)","volume":"20","author":"Ram\u00edrez","year":"2009","journal-title":"Vet. Dermatol"},{"key":"2019091012103078700_CIT0020","volume-title":"Trombic\u00falidos y trombiculiasis en La Rioja","author":"Santiba\u00f1ez-S\u00e1enz","year":"2015"},{"key":"2019091012103078700_CIT0021","doi-asserted-by":"crossref","first-page":"610","DOI":"10.1016\/j.eimc.2014.04.009","article-title":"Dermatitis pruriginosa tras paseo por la monta\u00f1a","volume":"32","author":"Santiba\u00f1ez-S\u00e1enz","year":"2014","journal-title":"Enferm. Infec. Micr. Cl"},{"key":"2019091012103078700_CIT0022","volume-title":"Muller and Kirk\u2019s small animal dermatology","author":"Scott","year":"2001","edition":"6"},{"key":"2019091012103078700_CIT0023","doi-asserted-by":"crossref","first-page":"81","DOI":"10.1111\/j.1365-3164.2005.00495.x","article-title":"Dermatitis in a dog induced by Straelensia cynotis: a case report and review of the literature","volume":"17","author":"Seixas","year":"2006","journal-title":"Vet. Dermatol"},{"key":"2019091012103078700_CIT0024","doi-asserted-by":"crossref","first-page":"33","DOI":"10.1007\/s10493-014-9809-8","article-title":"Stylostome organization in feeding Leptotrombidium larvae (Acariformes: Trombiculidae)","volume":"64","author":"Shatrov","year":"2014","journal-title":"Exp. Appl. Acarol"},{"key":"2019091012103078700_CIT0025","doi-asserted-by":"crossref","first-page":"98","DOI":"10.1111\/j.1748-5827.2004.tb00210.x","article-title":"Treatment of Neotrombicula autumnalis dermatitis in dogs using two topical permethrin-pyriproxyfen combinations","volume":"45","author":"Smal","year":"2004","journal-title":"J. Small Anim. Pract"},{"key":"2019091012103078700_CIT0026","doi-asserted-by":"crossref","first-page":"90","DOI":"10.1186\/1756-3305-7-90","article-title":"Neotrombicula inopinata (Acari: Trombiculidae) - a possible causative agent of trombiculiasis in Europe","volume":"7","author":"Stekolnikov","year":"2014","journal-title":"Parasit. Vectors"},{"key":"2019091012103078700_CIT0027","doi-asserted-by":"crossref","first-page":"60","DOI":"10.1016\/j.vetpar.2016.03.009","article-title":"Chigger mites of the genus Ericotrombidium (Acariformes: Trombiculidae) attacking pets in Europe","volume":"221","author":"Stekolnikov","year":"2016","journal-title":"Vet. Parasitol"},{"key":"2019091012103078700_CIT0028","first-page":"306","article-title":"Trombiculidae harvest mites (Neotrombicula autumnalis) infestation in dog in winter season\u2014a case report","volume":"58","author":"Tudor","year":"2012","journal-title":"Sci. Works Ser. C Vet. Med"},{"key":"2019091012103078700_CIT0029","doi-asserted-by":"crossref","DOI":"10.1002\/9780470690505","volume-title":"Veterinary ectoparasites: biology, pathology and control","author":"Wall","year":"2001","edition":"2"},{"key":"2019091012103078700_CIT0030","first-page":"695","article-title":"Assessing the effectiveness of mitochondrial COI and 16S rRNA genes for DNA barcoding of farmland spiders in China","volume":"29","author":"Wang","year":"2018","journal-title":"Mitochondrial DNA A. DNA Mapp. Seq. Anal"}],"container-title":["Journal of Medical Entomology"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/academic.oup.com\/jme\/advance-article-pdf\/doi\/10.1093\/jme\/tjz071\/28697792\/tjz071.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"http:\/\/academic.oup.com\/jme\/article-pdf\/56\/5\/1389\/29590243\/tjz071.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,9,18]],"date-time":"2022-09-18T14:06:31Z","timestamp":1663509991000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/jme\/article\/56\/5\/1389\/5497768"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,5,23]]},"references-count":30,"journal-issue":{"issue":"5","published-online":{"date-parts":[[2019,5,23]]},"published-print":{"date-parts":[[2019,9,3]]}},"URL":"https:\/\/doi.org\/10.1093\/jme\/tjz071","relation":{},"ISSN":["0022-2585","1938-2928"],"issn-type":[{"value":"0022-2585","type":"print"},{"value":"1938-2928","type":"electronic"}],"subject":[],"published-other":{"date-parts":[[2019,9]]},"published":{"date-parts":[[2019,5,23]]}}}