{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,10]],"date-time":"2026-07-10T14:00:11Z","timestamp":1783692011865,"version":"3.55.0"},"reference-count":36,"publisher":"Oxford University Press (OUP)","issue":"1","license":[{"start":{"date-parts":[[2019,6,22]],"date-time":"2019-06-22T00:00:00Z","timestamp":1561161600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/journals\/pages\/open_access\/funder_policies\/chorus\/standard_publication_model"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2020,1,9]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>West Bengal, India, is inhabited by abundance and variety of insects that triggers sensitization in some humans to inhalant allergens and\/or insect stings\/venoms. Lack of research on this topic prevented accurate diagnosis and proper follow-up treatments to patients suffering from insect-induced allergies. The aim of our study was to identify the allergy-causing insects and evaluate resulting sensitization among a study population in West Bengal, India. The skin prick test (SPT) evaluated sensitivity of 450 patients who sought treatment at the Allergy and Asthma Research Center from July 2017 to June 2018. Eight insect allergens were tested: Common Black Ant (Lasius niger, Linnaeus 1758), Fire Ant (Solenopsis invicta, Buren 1972), Honey Bee (Apis cerana indica, Fabricius 1798), Common Wasp (Vespula vulgaris, Linnaeus 1758), Mosquito (Aedes aegypti, Linnaeus in Hasselquist 1762), American Cockroach (Periplaneta americana, Linnaeus 1758), House Fly (Musca domestica, Linnaeus 1758), and Grasshopper (Gesonula punctifrons, Stal 1861). From a total of 450 patients evaluated, 370 patients had positive SPT reaction from at least one of the 8 insect allergens tested. Sensitivity to some Hymenoptera insects (common black ant, 87.62%; fire ant, 84.59%; and honey bee, 67.02%) was found in higher proportion than non-Hymenoptera group (mosquito, 66.67%; American cockroach, 33.33%; house fly, 10.41%; and grasshopper, 5.14%). There was significant difference in sensitivity among child, adolescent, and adult (P &amp;lt; 0.001). While female patients showed more sensitivity than males to SPT, the difference was statistically insignificant. In regards to occupation, farmers and bee keepers were most sensitive of field workers sensitive to Hymenoptera-derived allergens.<\/jats:p>","DOI":"10.1093\/jme\/tjz088","type":"journal-article","created":{"date-parts":[[2019,6,22]],"date-time":"2019-06-22T11:50:06Z","timestamp":1561204206000},"page":"1-7","source":"Crossref","is-referenced-by-count":6,"title":["Assessment of Hymenoptera and Non-Hymenoptera Insect Bite and Sting Allergy Among Patients of Tropical Region of West Bengal, India"],"prefix":"10.1093","volume":"57","author":[{"given":"Arghya","family":"Laha","sequence":"first","affiliation":[{"name":"Allergology and Applied Entomology Research Laboratory, Post Graduate Department of Zoology, Barasat Government College, Kolkata, West Bengal, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tania","family":"Sarkar","sequence":"additional","affiliation":[{"name":"Allergology and Applied Entomology Research Laboratory, Post Graduate Department of Zoology, Barasat Government College, Kolkata, West Bengal, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Debarati","family":"Dey","sequence":"additional","affiliation":[{"name":"Department of Zoology, University of Calcutta, Kolkata, West Bengal, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Priti","family":"Mondal","sequence":"additional","affiliation":[{"name":"Allergology and Applied Entomology Research Laboratory, Post Graduate Department of Zoology, Barasat Government College, Kolkata, West Bengal, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Srijit","family":"Bhattacharya","sequence":"additional","affiliation":[{"name":"Post Graduate Department of Physics, Barasat Government College, Kolkata, West Bengal, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Saibal","family":"Moitra","sequence":"additional","affiliation":[{"name":"Allergy and Asthma Research Centre, Kolkata, West Bengal, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Goutam Kumar","family":"Saha","sequence":"additional","affiliation":[{"name":"Department of Zoology, University of Calcutta, Kolkata, West Bengal, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1513-1703","authenticated-orcid":false,"given":"Sanjoy","family":"Podder","sequence":"additional","affiliation":[{"name":"Allergology and Applied Entomology Research Laboratory, Post Graduate Department of Zoology, Barasat Government College, Kolkata, West Bengal, India"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[2019,6,22]]},"reference":[{"key":"2020010907380389400_CIT0001","doi-asserted-by":"crossref","first-page":"15400","DOI":"10.1073\/pnas.0907043106","article-title":"Honey bee aggression supports a link between gene regulation and behavioral evolution","volume":"106","author":"Alaux","year":"2009","journal-title":"Proc. Natl. Acad. Sci. USA"},{"key":"2020010907380389400_CIT0002","first-page":"125","article-title":"Comparison of specific immunoglobulin E with the skin prick test in the diagnosis of house dust mites and cockroach sensitization in patients with asthma and\/or allergic Rhinitis","volume":"50","author":"Alimuddin","year":"2018","journal-title":"Acta Med. Indones"},{"issue":"7","key":"2020010907380389400_CIT0003","doi-asserted-by":"crossref","first-page":"449","DOI":"10.1007\/s11882-014-0449-1","article-title":"Venom immunotherapy: an updated review","volume":"14","author":"Antol\u00edn-Am\u00e9rigo","year":"2014","journal-title":"Curr. Allergy Asthma Rep"},{"issue":"2","key":"2020010907380389400_CIT0004","doi-asserted-by":"crossref","first-page":"176","DOI":"10.1016\/j.jped.2013.08.009","article-title":"Respiratory allergy to moth: the importance of sensitization to Bombyx mori in children with asthma and rhinitis","volume":"90","author":"Araujo","year":"2014","journal-title":"J. Pediatr. (Rio J.)"},{"key":"2020010907380389400_CIT0005","doi-asserted-by":"crossref","first-page":"289","DOI":"10.1159\/000350207","article-title":"Every cockroach is beautiful to its mother","volume":"161","author":"Arruda","year":"2013","journal-title":"Int. Arch. Allergy Immunol"},{"key":"2020010907380389400_CIT0006","doi-asserted-by":"crossref","first-page":"419","DOI":"10.1016\/0091-6749(88)90014-0","article-title":"Imported fire ant allergy in young children: skin reactivity and serum IgE antibodies to venom and whole body extract","volume":"82","author":"Bahna","year":"1988","journal-title":"J. Allergy Clin. Immunol"},{"key":"2020010907380389400_CIT0007","first-page":"253","article-title":"Assessment of sensitization to insect aeroallergens among patients with allergic rhinitis in Yazd City, Iran","volume":"11","author":"Bemanian","year":"2012","journal-title":"Iran. J. Allergy. Asthma. Immunol"},{"key":"2020010907380389400_CIT0008","doi-asserted-by":"crossref","first-page":"506","DOI":"10.1016\/0021-8707(64)90082-6","article-title":"Insect allergy \u2013 preliminary studies of the cockroach","volume":"35","author":"Bernton","year":"1964","journal-title":"J. Allergy"},{"key":"2020010907380389400_CIT0009","doi-asserted-by":"crossref","first-page":"219","DOI":"10.1159\/000490805","article-title":"Spectrum of allergens and allergen biology in India","volume":"177","author":"Bhattacharya","year":"2018","journal-title":"Int. Arch. Allergy Immunol"},{"key":"2020010907380389400_CIT0010","doi-asserted-by":"crossref","first-page":"1467","DOI":"10.1111\/j.1365-2222.2009.03324.x","article-title":"The natural history and epidemiology of insect venom allergy: clinical implications","volume":"39","author":"Bil\u00f2","year":"2009","journal-title":"Clin. Exp. Allergy"},{"key":"2020010907380389400_CIT0011","doi-asserted-by":"crossref","first-page":"18","DOI":"10.1111\/j.1398-9995.2011.02728.x","article-title":"Practical guide to skin prick tests in allergy to aeroallergens","volume":"67","author":"Bousquet","year":"2012","journal-title":"Allergy"},{"key":"2020010907380389400_CIT0012","first-page":"79","volume-title":"State statistical handbook","author":"Bureau of Applied Economics and Statistics, Department of Statistics and Programme Implementation, Government of West Bengal","year":"2015"},{"issue":"3","key":"2020010907380389400_CIT0013","doi-asserted-by":"crossref","first-page":"225","DOI":"10.32677\/IJCH.2016.v03.i03.011","article-title":"Prevalence study of common environmental allergens in children with asthma and allergic rhinitis in Kolkata: a hospital-based study","volume":"3","author":"Dey","year":"2016","journal-title":"Indian J. Child Health"},{"key":"2020010907380389400_CIT0014","doi-asserted-by":"crossref","first-page":"14","DOI":"10.1093\/jme\/tjx178","article-title":"Sensitivity to house dust mites allergens with atopic asthma and its relationship with CD14 C(-159T) polymorphism in patients of West Bengal, India","volume":"55","author":"Ghosh","year":"2017","journal-title":"J. Med. Entomol"},{"key":"2020010907380389400_CIT0015","doi-asserted-by":"crossref","first-page":"828","DOI":"10.1016\/0091-6749(88)90085-1","article-title":"Allergens in Hymenoptera venom. XXI. Cross-reactivity and multiple reactivity between fire ant venom and bee and wasp venoms","volume":"82","author":"Hoffman","year":"1988","journal-title":"J. Allergy Clin. Immunol"},{"key":"2020010907380389400_CIT0016","doi-asserted-by":"crossref","first-page":"249","DOI":"10.1007\/s10841-005-5094-5","article-title":"Diversity of some insect fauna in industrial and non-industrial areas of West Bengal, India","volume":"10","author":"Jana","year":"2006","journal-title":"J. Insect Conserv"},{"key":"2020010907380389400_CIT0017","first-page":"102","article-title":"Mosquito (Culex quinquefasciatus) induced IgE response is type I allergic respiratory disorders: a clinico immunologic studies","volume":"19","author":"Kausar","year":"2005","journal-title":"Indian J. Allergy Asthma Immunol"},{"key":"2020010907380389400_CIT0018","first-page":"75","article-title":"Stinging insect allergy: current perspectives on venom immunotherapy","volume":"8","author":"Ludman","year":"2015","journal-title":"J. Asthma Allergy"},{"key":"2020010907380389400_CIT0019","doi-asserted-by":"crossref","first-page":"e98","DOI":"10.2500\/ajra.2010.24.3529","article-title":"Effect of area of residence on patterns of aeroallergen sensitization in atopic patients","volume":"24","author":"Mahesh","year":"2010","journal-title":"Am. J. Rhinol. Allergy"},{"key":"2020010907380389400_CIT0020","doi-asserted-by":"crossref","first-page":"311","DOI":"10.4103\/ijd.IJD_438_17","article-title":"Common allergens prevalent in and around Ambala, Haryana: an intradermal study among patients with asthma and allergic rhinitis and atopic dermatitis","volume":"63","author":"Mehta","year":"2018","journal-title":"Indian J. Dermatol"},{"key":"2020010907380389400_CIT0021","doi-asserted-by":"crossref","first-page":"522","DOI":"10.1016\/B978-0-7234-3691-1.00056-8","article-title":"Allergic reactions to stinging and biting insects,","volume-title":"Clinical immunology","author":"Muller","year":"2013","edition":"4th ed."},{"key":"2020010907380389400_CIT0022","doi-asserted-by":"crossref","first-page":"54","DOI":"10.1016\/S1081-1206(10)60405-X","article-title":"Prevalence of allergic sensitization to imported fire ants in children living in an endemic region of the southeastern United States","volume":"100","author":"Partridge","year":"2008","journal-title":"Ann. Allergy Asthma Immunol"},{"issue":"4","key":"2020010907380389400_CIT0023","first-page":"431","article-title":"Prevalence of allergen sensitivity in nasobronchial allergy in Gujarat, India","volume":"2","author":"Patel","year":"2012","journal-title":"Natl. J. Med. Res"},{"key":"2020010907380389400_CIT0024","doi-asserted-by":"crossref","first-page":"621","DOI":"10.1111\/all.12812","article-title":"Mosquito salivary allergen Aed a 3: cloning, comprehensive molecular analysis, and clinical evaluation","volume":"71","author":"Peng","year":"2016","journal-title":"Allergy"},{"key":"2020010907380389400_CIT0025","doi-asserted-by":"crossref","first-page":"70","DOI":"10.4103\/0970-2113.53228","article-title":"A study of skin sensitivity to various allergens by skin prick test in patients of nasobronchial allergy","volume":"26","author":"Prasad","year":"2009","journal-title":"Lung India"},{"key":"2020010907380389400_CIT0026","first-page":"238","article-title":"Insect stings: clinical features and management","volume":"109","author":"Przybilla","year":"2012","journal-title":"Dtsch. Arztebl. Int"},{"key":"2020010907380389400_CIT0027","doi-asserted-by":"crossref","first-page":"4643","DOI":"10.1021\/pr300451g","article-title":"Proteomic view of the venom from the fire ant Solenopsis invicta Buren","volume":"11","author":"dos Santos Pinto","year":"2012","journal-title":"J. Proteome Res"},{"key":"2020010907380389400_CIT0028","doi-asserted-by":"crossref","first-page":"521","DOI":"10.1146\/annurev.en.35.010190.002513","article-title":"Integrated suppression of synanthropic cockroaches","volume":"35","author":"Schal","year":"1990","journal-title":"Annu. Rev. Entomol"},{"key":"2020010907380389400_CIT0029","doi-asserted-by":"crossref","first-page":"1033","DOI":"10.1111\/j.1365-2222.2007.02751.x","article-title":"Biological potency of German cockroach allergen extracts determined in an inner city population","volume":"37","author":"Slater","year":"2007","journal-title":"Clin. Exp. Allergy"},{"key":"2020010907380389400_CIT0030","doi-asserted-by":"crossref","first-page":"77","DOI":"10.3389\/fimmu.2014.00077","article-title":"Hymenoptera allergens: from venom to \u201cvenome\u201d","volume":"5","author":"Spillner","year":"2014","journal-title":"Front. Immunol"},{"key":"2020010907380389400_CIT0031","doi-asserted-by":"crossref","first-page":"7519","DOI":"10.1073\/pnas.1502408112","article-title":"New approaches narrow global species estimates for beetles, insects, and terrestrial arthropods","volume":"112","author":"Stork","year":"2015","journal-title":"Proc. Natl. Acad. Sci. U. S. A"},{"key":"2020010907380389400_CIT0032","first-page":"227","article-title":"Explaining odds ratios","volume":"19","author":"Szumilas","year":"2010","journal-title":"J. Can. Acad. Child Adolesc. Psychiatry"},{"issue":"1","key":"2020010907380389400_CIT0033","doi-asserted-by":"crossref","first-page":"30","DOI":"10.3390\/toxins8010030","article-title":"The biochemical toxin arsenal from ant venoms","volume":"8","author":"Touchard","year":"2016","journal-title":"Toxins"},{"key":"2020010907380389400_CIT0034","doi-asserted-by":"crossref","first-page":"249","DOI":"10.1580\/0953-9859-1.4.249","article-title":"Stinging insect allergy","volume":"1","author":"Warpinski","year":"1990","journal-title":"J. Wilderness Med"},{"key":"2020010907380389400_CIT0035","doi-asserted-by":"crossref","first-page":"56","DOI":"10.1159\/000236803","article-title":"Identification of a cross-reactive allergen (presumably tropomyosin) in shrimp, mite and insects","volume":"105","author":"Witteman","year":"1994","journal-title":"Int. Arch. Allergy Immunol"},{"key":"2020010907380389400_CIT0036","doi-asserted-by":"crossref","first-page":"169","DOI":"10.3389\/fimmu.2012.00169","article-title":"Role of female sex hormones, estradiol and progesterone, in mast cell behavior","volume":"3","author":"Zierau","year":"2012","journal-title":"Front. Immunol"}],"container-title":["Journal of Medical Entomology"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/academic.oup.com\/jme\/article-pdf\/57\/1\/1\/31775839\/tjz088.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"http:\/\/academic.oup.com\/jme\/article-pdf\/57\/1\/1\/31775839\/tjz088.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,1,7]],"date-time":"2021-01-07T08:59:30Z","timestamp":1610009970000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/jme\/article\/57\/1\/1\/5522039"}},"subtitle":[],"editor":[{"given":"David","family":"Florin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"editor"}]}],"short-title":[],"issued":{"date-parts":[[2019,6,22]]},"references-count":36,"journal-issue":{"issue":"1","published-online":{"date-parts":[[2019,6,22]]},"published-print":{"date-parts":[[2020,1,9]]}},"URL":"https:\/\/doi.org\/10.1093\/jme\/tjz088","relation":{},"ISSN":["0022-2585","1938-2928"],"issn-type":[{"value":"0022-2585","type":"print"},{"value":"1938-2928","type":"electronic"}],"subject":[],"published-other":{"date-parts":[[2020,1]]},"published":{"date-parts":[[2019,6,22]]}}}