{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,6]],"date-time":"2026-10-06T10:52:10Z","timestamp":1791283930811,"version":"4.1.0"},"reference-count":61,"publisher":"Oxford University Press (OUP)","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Ixodid ticks vector pathogens of humans, livestock, and wildlife, and occur in tropical and temperate regions worldwide. We used the lone star tick, Amblyomma americanum (L.) (Ixodida: Ixodidae), as a model for other ixodid species, including the southern cattle fever tick, Rhipicephalus (Boophilus) microplus (Canestrini) (Ixodida: Ixodidae). We assessed the lethality of CimeXa, an inert silica-based desiccant dust, and Drione, a silica-based desiccant dust with pyrethrin and piperonyl butoxide (PBO), against A. americanum larvae and nymphs on calves. CimeXa was highly lethal to larvae released onto shaved calf skin 72\u201396 h previously, and moderately toxic to nymphs. It did not affect immature life stages treated after they began feeding because desiccation was offset by ingestion of blood. Being inert, CimeXa can protect cattle from infestation before feeding occurs for a potentially indefinite period of time. Drione killed immatures within 24 h when released on treated skin and when applied to feeding ixodids because of the pyrethrin and PBO (PBO will also reduce resistance to pyrethrin if it develops). When CimeXa was applied to calves with the hair intact, \u224890% and \u224870% of A. americanum larvae and nymphs, respectively, were killed within 24 h and Drione killed 100% of each life stage. Drione also prevented and drastically reduced egg production and hatching. While CimeXa protects against infestation by immatures, Drione will also control ticks that are feeding. When pyrethrin and PBO in Drione eventually degrade, the silica aerogel carrier can continue to protect against infestation indefinitely.<\/jats:p>","DOI":"10.1093\/jme\/tjz180","type":"journal-article","created":{"date-parts":[[2019,10,16]],"date-time":"2019-10-16T21:39:08Z","timestamp":1571261948000},"source":"Crossref","is-referenced-by-count":4,"title":["Effects of Silica-Based CimeXa and Drione Dusts Against Lone Star Tick (Ixodida: Ixodidae) on Cattle"],"prefix":"10.1093","author":[{"given":"Allan T","family":"Showler","sequence":"first","affiliation":[{"name":"USDA-ARS, Knipling-Bushland U.S. Livestock Insects Research Laboratory, Kerrville, TX"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jessica L","family":"Harlien","sequence":"additional","affiliation":[{"name":"USDA-ARS, Knipling-Bushland U.S. Livestock Insects Research Laboratory, Kerrville, TX"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[2019,10,16]]},"reference":[{"key":"2019101613385330900_CIT0001","doi-asserted-by":"crossref","first-page":"6","DOI":"10.1016\/j.vetpar.2014.03.006","article-title":"Acaricide resistance in cattle ticks and approaches to its management: the state of play","volume":"203","author":"Abbas","year":"2014","journal-title":"Vet. 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