{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,1]],"date-time":"2026-05-01T08:18:46Z","timestamp":1777623526090,"version":"3.51.4"},"reference-count":22,"publisher":"Elsevier BV","issue":"8","license":[{"start":{"date-parts":[[1977,8,1]],"date-time":"1977-08-01T00:00:00Z","timestamp":239241600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["The Journal of Nutrition"],"published-print":{"date-parts":[[1977,8]]},"DOI":"10.1093\/jn\/107.8.1507","type":"journal-article","created":{"date-parts":[[2018,1,15]],"date-time":"2018-01-15T06:05:16Z","timestamp":1515996316000},"page":"1507-1512","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":26,"title":["Glycolytic, Hexose Monophosphate Shunt and Bactericidal Activities of Leukocytes in Ascorbic Acid Deficient Guinea Pigs"],"prefix":"10.1016","volume":"107","author":[{"given":"Prakash G.","family":"Shilotri","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1093\/jn\/107.8.1507_bib1","unstructured":"Scrimshaw, N. S., Taylor, C. E. & Gordon, J. E. (1968) Determinants of the effects of nutrition in infection. In: Interactions of Nutrition and Infection, pp. 143\u2013182, World Health Organization, Monograph Series N o. 57, Geneva."},{"key":"10.1093\/jn\/107.8.1507_bib2","unstructured":"Gontzea, I. (1974) Importance of vitamins. In: Nutrition and Anti-Infectious Defence, 2nd Edition ( Gontzea, I. & Florin, R. J., eds.) pp. 110\u2013166, Amold-Bocklin-Strasse 25, CH-4011 Basel (Switzerland)"},{"key":"10.1093\/jn\/107.8.1507_bib3","doi-asserted-by":"crossref","first-page":"143","DOI":"10.1152\/physrev.1962.42.1.143","article-title":"Metabolic basis of phagocytic activity","volume":"42","author":"Karnovsky","year":"1962","journal-title":"Physiol. Rev"},{"key":"10.1093\/jn\/107.8.1507_bib4","doi-asserted-by":"crossref","unstructured":"Selvaraj, R. J. & Sbarra, A. J. (1966) Relationship of glycolytic and oxidative metabolism to particle entry and destruction in phagocytosing cells, Nature 211, 1272\u20131276.","DOI":"10.1038\/2111272a0"},{"key":"10.1093\/jn\/107.8.1507_bib5","doi-asserted-by":"crossref","first-page":"50","DOI":"10.1093\/infdis\/83.1.50","article-title":"The relationship between ascorbic acid and phagocytic activity","volume":"83","author":"Nungester","year":"1948","journal-title":"J. Infect. Dis"},{"key":"10.1093\/jn\/107.8.1507_bib6","doi-asserted-by":"crossref","first-page":"1355","DOI":"10.1016\/S0021-9258(18)70011-2","article-title":"The biochemical basis of phagocytosis. I. Metabolic changes during the ingestion of particles by polymorphonuclear leukocytes","volume":"234","author":"Sbarra","year":"1959","journal-title":"J. Biol. Chem"},{"key":"10.1093\/jn\/107.8.1507_bib7","doi-asserted-by":"crossref","unstructured":"Selvaraj, R. J. & Sbarra, A. J. (1967) Role of the phagocyte in host-parasite interactions. VII I. Effect of whole-body X irradiation on nicotinamides, lysosomal enzymes, and bactericidal activities of leukocytes during phagocytosis. J. Bacteriol. 94, 149\u2013156.","DOI":"10.1128\/jb.94.1.149-156.1967"},{"key":"10.1093\/jn\/107.8.1507_bib8","doi-asserted-by":"crossref","first-page":"166","DOI":"10.1093\/ajcn\/25.2.166","article-title":"Metabolic and bactericidal activities of leukocytes in protein-calorie malnutrition","volume":"25","author":"Selvaraj","year":"1972","journal-title":"Amer. J. Clin. Nutr"},{"key":"10.1093\/jn\/107.8.1507_bib9","doi-asserted-by":"crossref","first-page":"535","DOI":"10.1016\/S0021-9258(18)51379-X","article-title":"The determination of lactic acid in biological material","volume":"138","author":"Barker","year":"1941","journal-title":"I. Biol. Chem"},{"key":"10.1093\/jn\/107.8.1507_bib10","first-page":"157","article-title":"The determination of ascorbic acid in white blood cells. A comparison of W.B.C. ascorbic acid and phenolic acid excretion in elderly patients","volume":"21","author":"Denson","year":"1961","journal-title":"Clin. Sci"},{"key":"10.1093\/jn\/107.8.1507_bib11","doi-asserted-by":"crossref","unstructured":"Snedecor, G. W. & Cochran, W. G. (1968) Statistical Methods, 6th ed. Oxford & IBH publishing Co. New Delhi.","DOI":"10.1097\/00010694-196809000-00018"},{"key":"10.1093\/jn\/107.8.1507_bib12","doi-asserted-by":"crossref","first-page":"59","DOI":"10.1093\/ajcn\/23.1.59","article-title":"Human requirements of ascorbic acid","volume":"23","author":"Srikantia","year":"1970","journal-title":"Am. J. Clin. Nutr"},{"key":"10.1093\/jn\/107.8.1507_bib13","doi-asserted-by":"crossref","unstructured":"Ericsson, Y. & Lundbeck H (1955) Antimicrobial effect in vitro of the ascorbic acid oxidation. I. Effect on bacteria, fungi and viruses in pure culture. Acta. Pathol. Microbiol. Scand. 37, 493\u2013506.","DOI":"10.1111\/j.1699-0463.1955.tb00975.x"},{"key":"10.1093\/jn\/107.8.1507_bib14","doi-asserted-by":"crossref","unstructured":"Miller, T. E. (1969) Killing and lysis of gram negative bacteria through the synergistic effect of hydrogen peroxide ascorbic acid, and lysozyme. J. Bacteriol. 98, 949\u2013955.","DOI":"10.1128\/jb.98.3.949-955.1969"},{"key":"10.1093\/jn\/107.8.1507_bib15","doi-asserted-by":"crossref","first-page":"194","DOI":"10.1093\/infdis\/124.2.194","article-title":"The effects of ascorbic acid on bactericidal mechanisms of neutrophils","volume":"124","author":"McCall","year":"1971","journal-title":"J. Infect. Dis"},{"key":"10.1093\/jn\/107.8.1507_bib16","doi-asserted-by":"crossref","first-page":"156","DOI":"10.1128\/iai.12.2.252-256.1975","article-title":"Ascorbate and phagocyte function","volume":"12","author":"Stankova","year":"1975","journal-title":"Infect. Immun"},{"key":"10.1093\/jn\/107.8.1507_bib17","doi-asserted-by":"crossref","first-page":"762","DOI":"10.1093\/ajcn\/29.7.762","article-title":"Macrophage function in vitamin C deficient guinea pigs","volume":"29","author":"Ganguly","year":"1976","journal-title":"Am. J. Clin. Nutr"},{"key":"10.1093\/jn\/107.8.1507_bib18","doi-asserted-by":"crossref","first-page":"611","DOI":"10.1111\/j.1365-2141.1973.tb01774.x","article-title":"The effect of ascorbate on the maintenance of 2, 3-diphosphoglycerate (2, 3-DPG) in stored red cells","volume":"25","author":"Wood","year":"1973","journal-title":"Br. J. Hematol"},{"key":"10.1093\/jn\/107.8.1507_bib19","doi-asserted-by":"crossref","first-page":"4848","DOI":"10.1016\/S0021-9258(18)99643-2","article-title":"Con trol of glycolysis in the human red blood cell","volume":"241","author":"Rose","year":"1966","journal-title":"J. Biol. Chem"},{"key":"10.1093\/jn\/107.8.1507_bib20","doi-asserted-by":"crossref","first-page":"979","DOI":"10.1016\/S0021-9258(18)64228-0","article-title":"Metabolic studies on scorbutic guinea pigs. I. Hepatic glucose-6-phosphate metabolism","volume":"236","author":"Ganguli","year":"1961","journal-title":"J. Biol. Chem"},{"key":"10.1093\/jn\/107.8.1507_bib21","doi-asserted-by":"crossref","first-page":"271","DOI":"10.1016\/S0021-9258(18)70393-1","article-title":"Occurrence and control of the phosphogluconate oxidation pathway in normal and leukemic leukocytes","volume":"232","author":"Beck","year":"1958","journal-title":"J. Biol. Chem"},{"key":"10.1093\/jn\/107.8.1507_bib22","first-page":"327","article-title":"Leukocyte preservation. I. Phagocytic stimulation of the hexose monophosphate shunt as a measure of cell viability","volume":"73","author":"Skeel","year":"1969","journal-title":"J. Lab. Clin. Med"}],"container-title":["The Journal of Nutrition"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0022316623271849?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0022316623271849?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/academic.oup.com\/jn\/article-pdf\/107\/8\/1507\/24050812\/jn1070081507.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,6,13]],"date-time":"2023-06-13T03:53:30Z","timestamp":1686628410000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0022316623271849"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1977,8]]},"references-count":22,"journal-issue":{"issue":"8","published-print":{"date-parts":[[1977,8]]}},"alternative-id":["S0022316623271849"],"URL":"https:\/\/doi.org\/10.1093\/jn\/107.8.1507","relation":{},"ISSN":["0022-3166"],"issn-type":[{"value":"0022-3166","type":"print"}],"subject":[],"published":{"date-parts":[[1977,8]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Glycolytic, Hexose Monophosphate Shunt and Bactericidal Activities of Leukocytes in Ascorbic Acid Deficient Guinea Pigs","name":"articletitle","label":"Article Title"},{"value":"The Journal of Nutrition","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1093\/jn\/107.8.1507","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 1977 American Society for Nutrition. Published by Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}]}}