{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,2]],"date-time":"2026-06-02T03:48:06Z","timestamp":1780372086154,"version":"3.54.1"},"reference-count":31,"publisher":"Elsevier BV","issue":"11","license":[{"start":{"date-parts":[[1979,11,1]],"date-time":"1979-11-01T00:00:00Z","timestamp":310262400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["The Journal of Nutrition"],"published-print":{"date-parts":[[1979,11]]},"DOI":"10.1093\/jn\/109.11.1925","type":"journal-article","created":{"date-parts":[[2018,1,15]],"date-time":"2018-01-15T06:10:36Z","timestamp":1515996636000},"page":"1925-1933","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":11,"title":["Production and Metabolism of Thyroid Hormones in Protein-Deficient and Food-Restricted Pregnant Rats"],"prefix":"10.1016","volume":"109","author":[{"given":"Mary M.","family":"Hastings","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Frances J.","family":"Zeman","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1093\/jn\/109.11.1925_bib1","first-page":"321","article-title":"Effect of different percentages of protein intake on thyroid activity, protein bound iodine, total thyroxine and free thyroxine level of blood of rats","volume":"62","author":"Deb","year":"1973","journal-title":"Endokrinologie"},{"key":"10.1093\/jn\/109.11.1925_bib2","doi-asserted-by":"crossref","first-page":"93","DOI":"10.1677\/joe.0.0460093","article-title":"Thyroid function in protein-depleted rats","volume":"46","author":"Florsheim","year":"1970","journal-title":"J. Endocrinol"},{"key":"10.1093\/jn\/109.11.1925_bib3","doi-asserted-by":"crossref","first-page":"267","DOI":"10.1210\/endo-73-2-267","article-title":"Thyroid function in female rats maintained on a protein-free diet","volume":"73","author":"Srebnik","year":"1963","journal-title":"Endocrinology"},{"key":"10.1093\/jn\/109.11.1925_bib4","doi-asserted-by":"crossref","first-page":"631","DOI":"10.3181\/00379727-110-27600","article-title":"Thyroxine secretion rates during food restriction in rats","volume":"110","author":"Grossie","year":"1962","journal-title":"Proc. Soc. Exp. Biol. Med"},{"key":"10.1093\/jn\/109.11.1925_bib5","doi-asserted-by":"crossref","first-page":"445","DOI":"10.1677\/joe.0.0500445","article-title":"Effect of decreased dietary protein on the rate of thyroid hormone secretion and food consumption in rats","volume":"50","author":"Singh","year":"1971","journal-title":"J. Endocrinol"},{"key":"10.1093\/jn\/109.11.1925_bib6","doi-asserted-by":"crossref","first-page":"273","DOI":"10.1152\/ajplegacy.1958.192.2.273","article-title":"Iodine metabolism in pregnancy","volume":"192","author":"Feldman","year":"1958","journal-title":"Am. J. Physiol"},{"key":"10.1093\/jn\/109.11.1925_bib7","first-page":"667","article-title":"Thyroidal radioiodine uptake as affected by protein deficiency and food restriction during pregnancy in the rat","volume":"16","author":"Hastings-Roberts","year":"1977","journal-title":"Nutr. Rep. Int"},{"key":"10.1093\/jn\/109.11.1925_bib8","doi-asserted-by":"crossref","first-page":"221","DOI":"10.1093\/jn\/107.2.221","article-title":"Thyroid function in prenatally protein-deprived rats","volume":"107","author":"Shrader","year":"1977","journal-title":"J. Nutr"},{"key":"10.1093\/jn\/109.11.1925_bib9","doi-asserted-by":"crossref","first-page":"213","DOI":"10.1093\/jn\/107.2.213","article-title":"Effect of prenatal protein deprivation on fetal neonatal thyroid morphology in the rat","volume":"107","author":"Shrader","year":"1977","journal-title":"J. Nutr"},{"key":"10.1093\/jn\/109.11.1925_bib10","doi-asserted-by":"crossref","first-page":"973","DOI":"10.1093\/jn\/107.6.973","article-title":"The effects of protein deficiency, pair-feeding or diet supplementation to the rat on maternal, fetal and placental growth","volume":"107","author":"Hastings-Roberts","year":"1976","journal-title":"J. Nutr"},{"key":"10.1093\/jn\/109.11.1925_bib11","doi-asserted-by":"crossref","first-page":"392","DOI":"10.1093\/jn\/106.3.392","article-title":"Adrenal function in young of protein deprived pregnant rats","volume":"106","author":"Parsons","year":"1976","journal-title":"J. Nutr"},{"key":"10.1093\/jn\/109.11.1925_bib12","unstructured":"Black, E. G., Griffiths, R. S., Finucane, J. & Hoffenberg R (1975) Radioimmunoassay of T3 and T4 in serum and urine. In: Thyroid Hormone Metabolism: Proceedings ( Harland, W. A. & Orr, J. S., eds.), pp. 347\u2013366, Academic Press, London."},{"key":"10.1093\/jn\/109.11.1925_bib13","doi-asserted-by":"crossref","first-page":"938","DOI":"10.1210\/jcem-34-6-938","article-title":"A radioimmunoassay for measurement of thyroxine in unextracted serum","volume":"34","author":"Chopra","year":"1972","journal-title":"J. Clin. Endocrinol. Metab"},{"key":"10.1093\/jn\/109.11.1925_bib14","first-page":"729","article-title":"An improved radioimmunoassay for measurement of triiodothyronine in human serum: its application to clinical and physiological studies","volume":"80","author":"Chopra","year":"1972","journal-title":"J. Lab. Clin. Med"},{"key":"10.1093\/jn\/109.11.1925_bib15","doi-asserted-by":"crossref","first-page":"949","DOI":"10.1136\/jcp.29.10.949","article-title":"A rapid and simple method for simultaneous measurement of serum free thyroxine and triiodothyronine fractions","volume":"29","author":"Finucane","year":"1976","journal-title":"J. Clin. Pathol"},{"key":"10.1093\/jn\/109.11.1925_bib16","doi-asserted-by":"crossref","first-page":"116","DOI":"10.1203\/00006450-197702000-00007","article-title":"Absence of placental transfer of L-triiodothyronine (T3) in the rat","volume":"11","author":"Dubois","year":"1977","journal-title":"Pediat. Res"},{"key":"10.1093\/jn\/109.11.1925_bib17","doi-asserted-by":"crossref","first-page":"435","DOI":"10.1210\/endo-101-2-435","article-title":"Ontogenesis of thyroid function in the neonatal rat. Thyroxine (T6) and triiodothyronine (T3) production rates","volume":"101","author":"Dubois","year":"1977","journal-title":"Endocrinology"},{"key":"10.1093\/jn\/109.11.1925_bib18","first-page":"351","article-title":"In vivo studies of thyroxine and triiodothyronine metabolism in the rat","volume":"85","author":"Zaninovich","year":"1977","journal-title":"Acta Endocrinol"},{"key":"10.1093\/jn\/109.11.1925_bib19","doi-asserted-by":"crossref","first-page":"806","DOI":"10.1172\/JCI103333","article-title":"Radiothyroxine turnover studies in myxedema, thyrotoxicosis, and hypermetabolism without endocrine disease","volume":"35","author":"Sterling","year":"1956","journal-title":"J. Clin. Invest"},{"key":"10.1093\/jn\/109.11.1925_bib20","doi-asserted-by":"crossref","first-page":"1133","DOI":"10.1210\/endo-94-4-1133","article-title":"Effects of thyrotropin-releasing hormone (TRH) in maternal, fetal and newborn rats","volume":"94","author":"Kojima","year":"1974","journal-title":"Endocrinology"},{"key":"10.1093\/jn\/109.11.1925_bib21","first-page":"59","article-title":"Ontogenesis of hypothalamic-pituitary-thyroid function and metabolism in man sheep and rat","volume":"33","author":"Fisher","year":"1977","journal-title":"Recent Prog. Horm. Res"},{"key":"10.1093\/jn\/109.11.1925_bib22","unstructured":"Alder, H. L. & Roessler, E. B. (1968) Probability and Statistic s. Freeman, San Francisco."},{"key":"10.1093\/jn\/109.11.1925_bib23","first-page":"1072","article-title":"Paradoxical effects of starvation and cortisone administration on free thyroxine concentration and thyroxine metabolism","volume":"45","author":"Schussler","year":"1966","journal-title":"J. Clin. Invest"},{"key":"10.1093\/jn\/109.11.1925_bib24","first-page":"354","article-title":"Thyroid function in protein malnutrition","volume":"62","author":"Talwalkar","year":"1974","journal-title":"Indian J. Med. Res"},{"key":"10.1093\/jn\/109.11.1925_bib25","first-page":"90","article-title":"Effect of some anesthetics on the level of free thyroxine in human and rat blood sera","volume":"62","author":"Michajlovskij","year":"1973","journal-title":"Endokrinologie"},{"key":"10.1093\/jn\/109.11.1925_bib26","doi-asserted-by":"crossref","first-page":"197","DOI":"10.1210\/jcem-42-1-197","article-title":"Effect of caloric restriction and dietary composition on serum T3 and reverse T3 in man","volume":"41","author":"Spaulding","year":"1976","journal-title":"J. Clin. Endocrinol. Metab"},{"key":"10.1093\/jn\/109.11.1925_bib27","doi-asserted-by":"crossref","first-page":"511","DOI":"10.1210\/endo-79-3-511","article-title":"Alterations in thyroid physiology during pneumococcal septicemia in the rat","volume":"79","author":"Shambaugh","year":"1966","journal-title":"Endocrinology"},{"key":"10.1093\/jn\/109.11.1925_bib28","doi-asserted-by":"crossref","first-page":"435","DOI":"10.1210\/endo-81-3-435","article-title":"Increased free thyroxine postoperatively in the rat","volume":"81","author":"Haibach","year":"1967","journal-title":"Endocrinology"},{"key":"10.1093\/jn\/109.11.1925_bib29","doi-asserted-by":"crossref","first-page":"282","DOI":"10.1210\/endo-82-2-282","article-title":"Thyroxine metabolism and thyroid function in the pregnant rat","volume":"82","author":"Galton","year":"1968","journal-title":"Endocrinology"},{"key":"10.1093\/jn\/109.11.1925_bib30","unstructured":"Fisher, D. A. & Dussault, J. H. (1974) Development of the mammalian thyroid gland. In: Handbook of Physiology, se c. 7, vo l. III, pp. 21\u201338, Amer. Physiol. So c. Washington, D.C."},{"key":"10.1093\/jn\/109.11.1925_bib31","doi-asserted-by":"crossref","first-page":"701","DOI":"10.1113\/jphysiol.1970.sp009038","article-title":"The effect of diet and acute starvation on the deiodination of thyroxine and triiodothyronine in the thyroidectomized rat","volume":"206","author":"Nathanielsz","year":"1970","journal-title":"J. Physiol"}],"container-title":["The Journal of Nutrition"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0022316623278232?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0022316623278232?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/academic.oup.com\/jn\/article-pdf\/109\/11\/1925\/23222350\/jn1090111925.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,6,13]],"date-time":"2023-06-13T04:08:08Z","timestamp":1686629288000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0022316623278232"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1979,11]]},"references-count":31,"journal-issue":{"issue":"11","published-print":{"date-parts":[[1979,11]]}},"alternative-id":["S0022316623278232"],"URL":"https:\/\/doi.org\/10.1093\/jn\/109.11.1925","relation":{},"ISSN":["0022-3166"],"issn-type":[{"value":"0022-3166","type":"print"}],"subject":[],"published":{"date-parts":[[1979,11]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Production and Metabolism of Thyroid Hormones in Protein-Deficient and Food-Restricted Pregnant Rats","name":"articletitle","label":"Article Title"},{"value":"The Journal of Nutrition","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1093\/jn\/109.11.1925","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 1979 American Society for Nutrition. Published by Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}]}}