{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,9,10]],"date-time":"2025-09-10T21:40:39Z","timestamp":1757540439630},"reference-count":21,"publisher":"Elsevier BV","issue":"8","license":[{"start":{"date-parts":[[1982,8,1]],"date-time":"1982-08-01T00:00:00Z","timestamp":397008000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["The Journal of Nutrition"],"published-print":{"date-parts":[[1982,8]]},"DOI":"10.1093\/jn\/112.8.1626","type":"journal-article","created":{"date-parts":[[2018,1,8]],"date-time":"2018-01-08T07:54:29Z","timestamp":1515398069000},"page":"1626-1630","update-policy":"http:\/\/dx.doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":15,"title":["The Biological Activity of Retinotaurine"],"prefix":"10.1016","volume":"112","author":[{"given":"K.L.","family":"Skare","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"W.K.","family":"Sietsema","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"H.F.","family":"DeLuca","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1093\/jn\/112.8.1626_bib1","doi-asserted-by":"crossref","first-page":"735","DOI":"10.1093\/jn\/9.6.735","article-title":"Changes in the vaginal epithelium of the rat after vitamin A deficiency.","volume":"9","author":"Mason","year":"1935","journal-title":"J. Nutr."},{"key":"10.1093\/jn\/112.8.1626_bib2","doi-asserted-by":"crossref","first-page":"587","DOI":"10.1073\/pnas.46.5.587","article-title":"The biological function of vitamin A acid.","volume":"46","author":"Dowling","year":"1960","journal-title":"Proc. Nati. Acad. Sci. USA"},{"key":"10.1093\/jn\/112.8.1626_bib3","series-title":"Experimental Lung Cancer. Carcinogenesis and Bioassays","first-page":"575","article-title":"The reversai of keratinized squamous metaplastic lesions of vitamin A deficiency in tracheobronchial epithelium by vitamin A and vitamin A analogs in organ culture: a model System for anti-carcinogenesis studies.","author":"Sporn","year":"1974"},{"key":"10.1093\/jn\/112.8.1626_bib4","doi-asserted-by":"crossref","first-page":"417","DOI":"10.1126\/science.76.1975.417","article-title":"The vag-inai smear method of determining vitamin A.","volume":"76","author":"Baumann","year":"1932","journal-title":"Science"},{"key":"10.1093\/jn\/112.8.1626_bib5","first-page":"1097","article-title":"Re-lationships among retinoid structure, inhibition of growth, and cellular retinole acid binding protein in cultured S91 melanoma cells.","volume":"40","author":"Lotan","year":"1980","journal-title":"Cancer Res."},{"key":"10.1093\/jn\/112.8.1626_bib6","doi-asserted-by":"crossref","first-page":"365","DOI":"10.1093\/jn\/28.5.365","article-title":"The biological assay of vitamin A by means of its influence on the cellular contents of the vagina of rats.","volume":"28","author":"Pugsley","year":"1944","journal-title":"J. Nutr."},{"key":"10.1093\/jn\/112.8.1626_bib7","first-page":"3413","article-title":"Structure-activity relationships of retinoids in hamster tracheal organ culture.","volume":"40","author":"Newton","year":"1980","journal-title":"Cancer Res."},{"key":"10.1093\/jn\/112.8.1626_bib8","doi-asserted-by":"crossref","first-page":"110","DOI":"10.1038\/263110a0","article-title":"Relationships between structure and activity of retinoids.","volume":"263","author":"Sporn","year":"1976","journal-title":"Nature London"},{"key":"10.1093\/jn\/112.8.1626_bib9","doi-asserted-by":"crossref","DOI":"10.1021\/bi00257a010","article-title":"Biliary metabolites of all-trans- retinoic acid in the rat: isolation and identification of a novel polar metabolite.","author":"Skare","year":"1982","journal-title":"Biochemistry"},{"key":"10.1093\/jn\/112.8.1626_bib10","doi-asserted-by":"crossref","first-page":"309","DOI":"10.1002\/aja.1000950207","article-title":"Effect of locally applied vitamin A and estrogen on the rat vagina.","volume":"95","author":"Kahn","year":"1954","journal-title":"Am. J. Anat."},{"key":"10.1093\/jn\/112.8.1626_bib11","doi-asserted-by":"crossref","first-page":"1481","DOI":"10.1093\/jn\/112.8.1481","article-title":"A new vaginal smear assay for vitamin A.","volume":"112","author":"Sietsema","year":"1982","journal-title":"J. Nutr."},{"key":"10.1093\/jn\/112.8.1626_bib12","doi-asserted-by":"crossref","first-page":"383","DOI":"10.1093\/jn\/81.4.383","article-title":"Action of vitamin A on liver homog-enate oxidation of tricarboxylic acid cycle inter-mediates.","volume":"81","author":"DeLuca","year":"1963","journal-title":"J. Nutr."},{"key":"10.1093\/jn\/112.8.1626_bib13","doi-asserted-by":"crossref","first-page":"1049","DOI":"10.1093\/jn\/100.9.1049","article-title":"Biological activity of 25-hydroxyergocalciferol in rats.","volume":"100","author":"Suda","year":"1970","journal-title":"J. Nutr."},{"key":"10.1093\/jn\/112.8.1626_bib14","doi-asserted-by":"crossref","first-page":"43","DOI":"10.1002\/9780470110201.ch2","article-title":"Determination of vitamin A.","volume":"4","author":"Embree","year":"1957","journal-title":"Methods Biochem. Anal."},{"key":"10.1093\/jn\/112.8.1626_bib15","doi-asserted-by":"crossref","first-page":"195","DOI":"10.1113\/expphysiol.1938.sp000774","article-title":"Mechanism of oestrus inhibition in the mouse during pregnancy.","volume":"28","author":"Robson","year":"1938","journal-title":"Q. J. Exp. Physiol."},{"key":"10.1093\/jn\/112.8.1626_bib16","doi-asserted-by":"crossref","first-page":"2225","DOI":"10.1093\/jn\/110.11.2225","article-title":"The biological activity of 5,6-epoxyretinoic acid.","volume":"110","author":"Zile","year":"1980","journal-title":"J. Nutr."},{"key":"10.1093\/jn\/112.8.1626_bib17","first-page":"9","article-title":"Ar-otinoids, a new class of highly active retinoids.","volume":"15","author":"Loeliger","year":"1980","journal-title":"Eur. J. Med. Chem."},{"key":"10.1093\/jn\/112.8.1626_bib18","series-title":"Vitamin A","first-page":"277","article-title":"Biological activity of congenere of vitamin A.","author":"Moore","year":"1957"},{"key":"10.1093\/jn\/112.8.1626_bib19","doi-asserted-by":"crossref","first-page":"153","DOI":"10.1079\/PNS19650028","article-title":"Chemical structure and vitamin A activity.","volume":"24","author":"Pitt","year":"1965","journal-title":"Proc. Nutr. Soc."},{"key":"10.1093\/jn\/112.8.1626_bib20","series-title":"Carotenoids","first-page":"717","article-title":"Vitamin A.","author":"Pitt","year":"1971"},{"key":"10.1093\/jn\/112.8.1626_bib21","first-page":"374","article-title":"Metabolism of all-trans- retinoic acid in hamster liver microsomes: Oxidation of 4-hydroxy-to 4-keto-retinoic acid. Arch. Biochem.","volume":"199","author":"Roberts","year":"1980","journal-title":"Biophys"}],"container-title":["The Journal of Nutrition"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0022316623198944?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0022316623198944?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/academic.oup.com\/jn\/article-pdf\/112\/8\/1626\/23997458\/jn1120081626.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,8,30]],"date-time":"2023-08-30T13:04:42Z","timestamp":1693400682000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0022316623198944"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1982,8]]},"references-count":21,"journal-issue":{"issue":"8","published-print":{"date-parts":[[1982,8]]}},"alternative-id":["S0022316623198944"],"URL":"https:\/\/doi.org\/10.1093\/jn\/112.8.1626","relation":{},"ISSN":["0022-3166"],"issn-type":[{"value":"0022-3166","type":"print"}],"subject":[],"published":{"date-parts":[[1982,8]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"The Biological Activity of Retinotaurine","name":"articletitle","label":"Article Title"},{"value":"The Journal of Nutrition","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1093\/jn\/112.8.1626","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 1982 American Society for Nutrition. Published by Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}]}}