{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2024,6,30]],"date-time":"2024-06-30T10:40:01Z","timestamp":1719744001984},"reference-count":63,"publisher":"Elsevier BV","issue":"10","license":[{"start":{"date-parts":[[1985,10,1]],"date-time":"1985-10-01T00:00:00Z","timestamp":496972800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["The Journal of Nutrition"],"published-print":{"date-parts":[[1985,10]]},"DOI":"10.1093\/jn\/115.10.1274","type":"journal-article","created":{"date-parts":[[2018,1,8]],"date-time":"2018-01-08T10:53:01Z","timestamp":1515408781000},"page":"1274-1284","update-policy":"http:\/\/dx.doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":18,"title":["Effects of Fructose Feeding on Lipid Parameters in Obese and Lean, Diabetic and Nondiabetic Zucker Rats"],"prefix":"10.1016","volume":"115","author":[{"given":"Eunsook T.","family":"Koh","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Janice","family":"Mueller","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Odutola","family":"Osilesi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Allen","family":"Knehans","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sheldon","family":"Reiser","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1093\/jn\/115.10.1274_bib1","series-title":"Metabolic Effects of Utilizable Carbohydrates","first-page":"1","article-title":"Recent trends and levels of dietary sugars and other sweeteners","author":"Woteki","year":"1882"},{"key":"10.1093\/jn\/115.10.1274_bib2","doi-asserted-by":"crossref","first-page":"195","DOI":"10.1111\/j.0954-6820.1972.tb05335.x","article-title":"Does dietary fructose affect the control of diabetes in children?","volume":"542","author":"Akerblom","year":"1972","journal-title":"Acta Med. Scand. (Suppl.)"},{"key":"10.1093\/jn\/115.10.1274_bib3","doi-asserted-by":"crossref","first-page":"499","DOI":"10.1016\/S0002-8223(21)05783-7","article-title":"Use of fructose, sorbitol, or xylitol as a sweetener in diabetes me\u0142litus","volume":"73","author":"Brunzell","year":"1978","journal-title":"J. Am. Diet Assoc"},{"key":"10.1093\/jn\/115.10.1274_bib4","series-title":"Sweeteners: Issues and Uncertainties","first-page":"35","article-title":"Perspective on sweeteners: patterns of use","author":"Cantor","year":"1975"},{"key":"10.1093\/jn\/115.10.1274_bib5","series-title":"CRC Handbook Series in Nutrition and Food, section E: Nutritional Disorders","first-page":"409","article-title":"Effect of nutrient excess in animals and man: carbohydrates","author":"Reiser","year":"1978"},{"key":"10.1093\/jn\/115.10.1274_bib6","doi-asserted-by":"crossref","first-page":"575","DOI":"10.2337\/diacare.3.5.575","article-title":"Effects of oral fructose in normal, diabetic, and impaired glucose tolerance subjects","volume":"3","author":"Crapo","year":"1980","journal-title":"Diabetes Care"},{"key":"10.1093\/jn\/115.10.1274_bib7","first-page":"180","article-title":"Comparative oral glucose and fructose tolerance tests in normal subjects and in diabetic patients","volume":"46","author":"Lamar","year":"1959","journal-title":"J. Fla. Med. Assoc"},{"key":"10.1093\/jn\/115.10.1274_bib8","first-page":"494","article-title":"The metabolism of fructose in diabetics","volume":"69","author":"Metz","year":"1969","journal-title":"J. Lab. Clin. Med"},{"key":"10.1093\/jn\/115.10.1274_bib9","doi-asserted-by":"crossref","first-page":"1305","DOI":"10.1093\/ajcn\/31.8.1305","article-title":"Some effects in man, of varying the load of glucose, sucrose, fructose, or sorbitol on various metabolites in blood","volume":"31","author":"Macdonald","year":"1978","journal-title":"Am. J. Clin. Nutr"},{"key":"10.1093\/jn\/115.10.1274_bib10","doi-asserted-by":"crossref","first-page":"262","DOI":"10.1159\/000176221","article-title":"Liver glycogen synthesis and glucose tolerance in rats adapted to diets with a high proportion of fructose or glucose","volume":"22","author":"Vr\u00e1na","year":"1978","journal-title":"Nutr. Metab"},{"key":"10.1093\/jn\/115.10.1274_bib11","doi-asserted-by":"crossref","first-page":"970","DOI":"10.1016\/0026-0495(80)90041-4","article-title":"Effect of fructose feeding on insulin secretion and insulin action in the rat","volume":"29","author":"Zavaroni","year":"1980","journal-title":"Metabolism"},{"key":"10.1093\/jn\/115.10.1274_bib12","doi-asserted-by":"crossref","first-page":"303","DOI":"10.1016\/0026-0495(80)90001-3","article-title":"Hyperinsulinemia in fructose-induced hypertriglyceridemia in the rat","volume":"29","author":"Sleder","year":"1980","journal-title":"Metabolism"},{"key":"10.1093\/jn\/115.10.1274_bib13","doi-asserted-by":"crossref","first-page":"91","DOI":"10.3181\/00379727-123-31411","article-title":"Enhancement of alimentary hyperglyceridemia by fructose and glycerol in man","volume":"123","author":"Nikkila","year":"1966","journal-title":"Proc. Soc. Exp. Biol. Med"},{"key":"10.1093\/jn\/115.10.1274_bib14","series-title":"Sugars in Nutrition","first-page":"439","article-title":"Influence of dietary fructose and sucrose on serum triglycerides in hypertriglyceridemia and diabetes","author":"Nikkila","year":"1974"},{"key":"10.1093\/jn\/115.10.1274_bib15","doi-asserted-by":"crossref","first-page":"187","DOI":"10.1111\/j.0954-6820.1972.tb05334.x","article-title":"Metabolic effects of dietary fructose in insulin dependent diabetes of adults","volume":"542","author":"Pelkonen","year":"1972","journal-title":"Acta Med. Scand. (Suppl.)"},{"key":"10.1093\/jn\/115.10.1274_bib16","doi-asserted-by":"crossref","first-page":"1043","DOI":"10.1093\/ajcn\/32.5.1043","article-title":"Effect of dietary fructose on triglyceride transport and glucoregulatory hormones in hypertriglyceridemic men","volume":"32","author":"TUrner","year":"1979","journal-title":"Am. J. Clin. Nutr"},{"key":"10.1093\/jn\/115.10.1274_bib17","doi-asserted-by":"crossref","first-page":"740","DOI":"10.1093\/ajcn\/37.5.740","article-title":"Blood lipid distribution of hyperinsulinemic men consuming three levels of fructose","volume":"37","author":"Hallfrisch","year":"1983","journal-title":"Am. J. Clin. Nutr"},{"key":"10.1093\/jn\/115.10.1274_bib18","doi-asserted-by":"crossref","first-page":"937","DOI":"10.1016\/0024-3205(65)90193-1","article-title":"Induction of hyperglyceridemia by fructose in the rat","volume":"4","author":"Nikkila","year":"1965","journal-title":"Life Sci"},{"key":"10.1093\/jn\/115.10.1274_bib19","doi-asserted-by":"crossref","first-page":"89","DOI":"10.1016\/0024-3205(66)90191-3","article-title":"Acute effects of fructose and glucose on the concentration and removal rate of plasma triglycerides","volume":"5","author":"Nikkila","year":"1966","journal-title":"Life Sci"},{"key":"10.1093\/jn\/115.10.1274_bib20","doi-asserted-by":"crossref","first-page":"95","DOI":"10.1093\/jn\/94.1.95","article-title":"Effect of glucose and fructose administration on lipid metabolism in the rat","volume":"94","author":"Bar-On","year":"1967","journal-title":"J. Nutr"},{"key":"10.1093\/jn\/115.10.1274_bib21","first-page":"450","article-title":"Role of the human liver in the assimilation of intravenously administered fructose","volume":"2","author":"Mendeloff","year":"1953","journal-title":"Metabolism"},{"key":"10.1093\/jn\/115.10.1274_bib22","doi-asserted-by":"crossref","first-page":"359","DOI":"10.1111\/j.0954-6820.1968.tb02471.x","article-title":"Lactic acid accumulation in connection with fructose infusion","volume":"184","author":"Bergstr\u00f6m","year":"1968","journal-title":"Acta Med. Scand"},{"key":"10.1093\/jn\/115.10.1274_bib23","doi-asserted-by":"crossref","first-page":"301","DOI":"10.1111\/j.1651-2227.1969.tb04723.x","article-title":"Increasing metabolic acidosis following fructose infusion in two children","volume":"58","author":"Anderson","year":"1969","journal-title":"Acta Pediatr. Scand"},{"key":"10.1093\/jn\/115.10.1274_bib24","doi-asserted-by":"crossref","first-page":"1665","DOI":"10.1001\/jama.1979.03290420003001","article-title":"High plasma insulin level \u2014 a prime risk factor for heart disease [new]","volume":"241","author":"Montgomery","year":"1979","journal-title":"JAMA (J. Am. Med. Assoc.)"},{"key":"10.1093\/jn\/115.10.1274_bib25","series-title":"Diabetes: Its Physiological and Biochemical Basis","first-page":"125","article-title":"Atherosclerosis and disorders of lipid metabolism in diabetes","author":"Stout","year":"1975"},{"key":"10.1093\/jn\/115.10.1274_bib26","doi-asserted-by":"crossref","first-page":"372","DOI":"10.1016\/0026-0495(70)90134-4","article-title":"Study of serum insulin in patients with endogenous hypertriglyceridemia","volume":"19","author":"Kuo","year":"1970","journal-title":"Metabolism"},{"key":"10.1093\/jn\/115.10.1274_bib27","first-page":"299","article-title":"Influence of diet composition on insulin output, carbohydrate tolerance and lipid values in primary hypertriglyceridemia (HT)","volume":"71","author":"Julius","year":"1978","journal-title":"Endokrinologie"},{"key":"10.1093\/jn\/115.10.1274_bib28","doi-asserted-by":"crossref","first-page":"1320","DOI":"10.1210\/endo-90-5-1320","article-title":"Insulin and obesity in the Zucker genetically obese rat \u201cfatty\u201d","volume":"90","author":"Zucker","year":"1972","journal-title":"Endocrinology"},{"key":"10.1093\/jn\/115.10.1274_bib29","doi-asserted-by":"crossref","first-page":"833","DOI":"10.1016\/0026-0495(69)90058-4","article-title":"Plasma triglycerides in genetically obese rats","volume":"18","author":"Ba\u03c0y","year":"1969","journal-title":"Metabolism"},{"key":"10.1093\/jn\/115.10.1274_bib30","doi-asserted-by":"crossref","first-page":"820","DOI":"10.1093\/jn\/113.4.820","article-title":"Effects of high fat and high carbohydrate diets on development of hepatic and adipose lipogenesis in fa\/fa and non-fa\/fa rats","volume":"113","author":"Be\u2019rke","year":"1983","journal-title":"J. Nutr"},{"key":"10.1093\/jn\/115.10.1274_bib31","doi-asserted-by":"crossref","first-page":"415","DOI":"10.1126\/science.180605","article-title":"Streptozotocin-induced pancreatic insulinitis: new model of diabetes mellitus","volume":"193","author":"Like","year":"1976","journal-title":"Science (Washington, DC)"},{"key":"10.1093\/jn\/115.10.1274_bib32","doi-asserted-by":"crossref","first-page":"2485","DOI":"10.1073\/pnas.74.6.2485","article-title":"Studies of streptozotocin-induced insulinitis and diabetes","volume":"74","author":"Rossini","year":"1977","journal-title":"Proc. Natl. Acad. Sci. USA"},{"key":"10.1093\/jn\/115.10.1274_bib33","doi-asserted-by":"crossref","first-page":"724","DOI":"10.2337\/diab.31.8.724","article-title":"Induction of insulin-dependent diabetes by streptozotocin. Inhibition by estrogens and potentiation by androgens","volume":"31","author":"Paik","year":"1982","journal-title":"Diabetes"},{"key":"10.1093\/jn\/115.10.1274_bib34","doi-asserted-by":"crossref","first-page":"1340","DOI":"10.1093\/jn\/107.7.1340","article-title":"Report of the AIN Ad Hoc Committee on Standards for Nutritional Studies","volume":"107","year":"1977","journal-title":"J. Nutr"},{"key":"10.1093\/jn\/115.10.1274_bib35","doi-asserted-by":"crossref","first-page":"101","DOI":"10.3109\/10408367309151554","article-title":"Methods for determining the amount of glucose in blood","volume":"4","author":"Cooper","year":"1973","journal-title":"CRC Crit. Rev. Clin. Lab. Sci"},{"key":"10.1093\/jn\/115.10.1274_bib36","doi-asserted-by":"crossref","first-page":"137","DOI":"10.1042\/bj0880137","article-title":"Immunoassay of insulin with insulin anti-body precipitate","volume":"88","author":"Hales","year":"1963","journal-title":"Biochem. J"},{"key":"10.1093\/jn\/115.10.1274_bib37","series-title":"Triglycerides, Enzyme Determination","year":"1977"},{"key":"10.1093\/jn\/115.10.1274_bib38","doi-asserted-by":"crossref","first-page":"1171","DOI":"10.1093\/clinchem\/15.12.1171","article-title":"Serum cholesterol assay using a stable Liebermann-Burchard reagent","volume":"15","author":"Kim","year":"1969","journal-title":"Clin. Chem"},{"key":"10.1093\/jn\/115.10.1274_bib39","series-title":"Lactic Acid, Enzymatic Determination, Sigma Technical Bulletin, No. 726-UV","year":"1984"},{"key":"10.1093\/jn\/115.10.1274_bib40","doi-asserted-by":"crossref","first-page":"497","DOI":"10.1016\/S0021-9258(18)64849-5","article-title":"A simple method for the isolation and purification of total lipides from animal tissues","volume":"226","author":"Folch","year":"1957","journal-title":"J. Biol. Chem"},{"key":"10.1093\/jn\/115.10.1274_bib41","series-title":"Statistical Methods","author":"Snedecor","year":"1967"},{"key":"10.1093\/jn\/115.10.1274_bib42","doi-asserted-by":"crossref","first-page":"229","DOI":"10.1093\/jn\/16.3.229","article-title":"The effects of a high fructose diet on the body weight and on the fat, glycogen, and nitrogen content of the liver and body of the albino rat","volume":"16","author":"Bachman","year":"1938","journal-title":"J. Nutr"},{"key":"10.1093\/jn\/115.10.1274_bib43","first-page":"371","article-title":"Rat feeding studies using unheated and heated mixtures of casein with fructose, glucose\/fructose, and sucrose","volume":"29","author":"Westing","year":"1984","journal-title":"Nutr. Rep. Int"},{"key":"10.1093\/jn\/115.10.1274_bib44","doi-asserted-by":"crossref","first-page":"461","DOI":"10.1038\/238461a0","article-title":"Sucrose induction of hepatic hyperplasia in the rat.","volume":"238","author":"Bender","year":"1972","journal-title":"Nature (London)"},{"key":"10.1093\/jn\/115.10.1274_bib45","doi-asserted-by":"crossref","first-page":"439","DOI":"10.1042\/bj1290439","article-title":"Fatty acid synthetase activity in the liver and adipose tissue of rats fed with various carbohydrates","volume":"129","author":"Bruckdorfer","year":"1972","journal-title":"Biochem. J"},{"key":"10.1093\/jn\/115.10.1274_bib46","doi-asserted-by":"crossref","first-page":"706","DOI":"10.2337\/diab.22.9.706","article-title":"Increased kidney size and glomerular filtration rate in early juvenile diabetes","volume":"22","author":"Mogensen","year":"1973","journal-title":"Diabetes"},{"key":"10.1093\/jn\/115.10.1274_bib47","doi-asserted-by":"crossref","first-page":"91","DOI":"10.3109\/00365517109090667","article-title":"Glomerular filtration rate and renal plasma flow in short-term and longterm juvenile diabetes.","volume":"28","author":"Mogensen","year":"1971","journal-title":"Scand. J. Clin. Lab. Invest"},{"key":"10.1093\/jn\/115.10.1274_bib48","doi-asserted-by":"crossref","first-page":"409","DOI":"10.1007\/BF00252690","article-title":"Renal function in streptozotocin-diabetic rats","volume":"21","author":"Jensen","year":"1981","journal-title":"Diabetologia"},{"key":"10.1093\/jn\/115.10.1274_bib49","doi-asserted-by":"crossref","first-page":"451","DOI":"10.1007\/BF00253406","article-title":"Increased kidney size, glomerular filtration rate and renal plasma flow in short-term insulin dependent diabetes","volume":"20","author":"Christiansen","year":"1981","journal-title":"Diabetologia"},{"key":"10.1093\/jn\/115.10.1274_bib50","doi-asserted-by":"crossref","first-page":"364","DOI":"10.1007\/BF00280522","article-title":"Modification of the glomerular basement membrane in sucrose-fed streptozotocin-diabetic rats","volume":"19","author":"Thylor","year":"1980","journal-title":"Diabetologia"},{"key":"10.1093\/jn\/115.10.1274_bib51","doi-asserted-by":"crossref","first-page":"418","DOI":"10.1007\/BF00252692","article-title":"Effect of early and chronic hyperinsulinism on adipose tissue cellularity in the rat","volume":"21","author":"Goursot","year":"1981","journal-title":"Diabetologia"},{"key":"10.1093\/jn\/115.10.1274_bib52","first-page":"175","article-title":"Metabolic and regulatory obesity in rats and man","volume":"2","author":"Bray","year":"1970","journal-title":"Hormone Metab. Res. Suppl"},{"key":"10.1093\/jn\/115.10.1274_bib53","doi-asserted-by":"crossref","first-page":"277","DOI":"10.1016\/0026-0495(72)90070-4","article-title":"Hyperin\u2261ulinemia and insulin resistance in genetically obese rats","volume":"21","author":"York","year":"1972","journal-title":"Metabolism"},{"key":"10.1093\/jn\/115.10.1274_bib54","first-page":"608612","article-title":"Mechanism of insulin resistance in fructose-fed rats","volume":"31","author":"Tbbey","year":"1982","journal-title":"Metabolism"},{"key":"10.1093\/jn\/115.10.1274_bib55","doi-asserted-by":"crossref","first-page":"289","DOI":"10.1159\/000175549","article-title":"The importance of stimulated immuno-reactive-insulin levels to early results of dietary management in hyperlipoproteinemia","volume":"17","author":"Valek","year":"1974","journal-title":"Nutr. Metab"},{"key":"10.1093\/jn\/115.10.1274_bib56","doi-asserted-by":"crossref","first-page":"165","DOI":"10.3181\/00379727-110-27455","article-title":"Hereditary obesity in the rat associated with high serum fat and cholesterol","volume":"110","author":"Zucker","year":"1962","journal-title":"Proc. Soc. Exp. Biol. Med"},{"key":"10.1093\/jn\/115.10.1274_bib57","first-page":"715","article-title":"Effect of fructose, glucose, sucrose, and starch on serum lipids in carbohydrate induced hypertriglyceridemia and in normal subjects","volume":"2","author":"Kaufmann","year":"1966","journal-title":"J. Med. Sci"},{"key":"10.1093\/jn\/115.10.1274_bib58","doi-asserted-by":"crossref","first-page":"394","DOI":"10.1093\/ajcn\/30.3.394","article-title":"Sucrose sensitivity of patients with coronary-artery disease","volume":"30","author":"Palumbo","year":"1977","journal-title":"Am. J. Clin. Nutr"},{"key":"10.1093\/jn\/115.10.1274_bib59","first-page":"1337","article-title":"Blood glucose and plasma lipids of Zucker rats fed diets containing cornstarch or sucrose","volume":"29","author":"Sheehan","year":"1984","journal-title":"Nutr. Rep. Int"},{"key":"10.1093\/jn\/115.10.1274_bib60","first-page":"1000","article-title":"Abnormal plasma insulin response with high plasma triglycerides independent of clinical diabetes or obesity","volume":"45","author":"Davidson","year":"1966","journal-title":"J. Clin. Invest"},{"key":"10.1093\/jn\/115.10.1274_bib61","doi-asserted-by":"crossref","first-page":"1756","DOI":"10.1172\/JCI105666","article-title":"Role of insulin in endogenous hypertriglyceridemia","volume":"46","author":"Reaven","year":"1969","journal-title":"J. Clin. Invest"},{"key":"10.1093\/jn\/115.10.1274_bib62","doi-asserted-by":"crossref","first-page":"419","DOI":"10.1093\/ajcn\/21.12.1419","article-title":"Serum insulin in obesity and diabetes me\u0142litus","volume":"21","author":"Boshell","year":"1968","journal-title":"Am. J. Clin. Nutr"},{"key":"10.1093\/jn\/115.10.1274_bib63","doi-asserted-by":"crossref","first-page":"621","DOI":"10.1007\/BF02531341","article-title":"Effect of fructose on rat lipids","volume":"5","author":"Hill","year":"1976","journal-title":"Lipid"}],"container-title":["The Journal of Nutrition"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0022316623076356?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0022316623076356?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/academic.oup.com\/jn\/article-pdf\/115\/10\/1274\/23998480\/jn1150101274.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,6,30]],"date-time":"2024-06-30T10:13:15Z","timestamp":1719742395000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0022316623076356"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1985,10]]},"references-count":63,"journal-issue":{"issue":"10","published-print":{"date-parts":[[1985,10]]}},"alternative-id":["S0022316623076356"],"URL":"https:\/\/doi.org\/10.1093\/jn\/115.10.1274","relation":{},"ISSN":["0022-3166"],"issn-type":[{"value":"0022-3166","type":"print"}],"subject":[],"published":{"date-parts":[[1985,10]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Effects of Fructose Feeding on Lipid Parameters in Obese and Lean, Diabetic and Nondiabetic Zucker Rats","name":"articletitle","label":"Article Title"},{"value":"The Journal of Nutrition","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1093\/jn\/115.10.1274","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 1985 American Society for Nutrition. Published by Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}]}}