{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,20]],"date-time":"2026-01-20T02:41:59Z","timestamp":1768876919777,"version":"3.49.0"},"reference-count":21,"publisher":"Elsevier BV","issue":"6","license":[{"start":{"date-parts":[[1988,6,1]],"date-time":"1988-06-01T00:00:00Z","timestamp":581126400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["The Journal of Nutrition"],"published-print":{"date-parts":[[1988,6]]},"DOI":"10.1093\/jn\/118.6.780","type":"journal-article","created":{"date-parts":[[2018,1,5]],"date-time":"2018-01-05T14:35:58Z","timestamp":1515162958000},"page":"780-786","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":30,"title":["Differences in Uricogenic Effects of Dietary Purine Bases, Nucleosides and Nucleotides in Rats"],"prefix":"10.1016","volume":"118","author":[{"given":"Danielle","family":"Brul\u00e9","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ghulam","family":"Sarwar","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Laurent","family":"Savoie","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"James","family":"Campbell","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Murray","family":"van Zeggelaar","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1093\/jn\/118.6.780_bib1","first-page":"17","article-title":"PAG ad hoc working group on clinical evaluation and acceptable nucleic acid levels of SCP for human consumption.","volume":"5","year":"1975","journal-title":"PAG Bull."},{"key":"10.1093\/jn\/118.6.780_bib2","doi-asserted-by":"crossref","first-page":"428","DOI":"10.1093\/jn\/106.3.428","article-title":"Effect of oral purines on serum and urinary uric acid of normal, hyperuricemic and gouty humans.","volume":"106","author":"CLIFFORD","year":"1976","journal-title":"J. Nutr."},{"key":"10.1093\/jn\/118.6.780_bib3","doi-asserted-by":"crossref","first-page":"519","DOI":"10.3177\/jnsv.28.519","article-title":"Metabolic effects of dietary purine in rats.","volume":"28","author":"YOKOZAWA","year":"1982","journal-title":"J. Nutr. Sci. Vitaminol."},{"key":"10.1093\/jn\/118.6.780_bib4","doi-asserted-by":"crossref","first-page":"229","DOI":"10.1016\/0041-008X(79)90316-8","article-title":"The toxicological effects of pure dietary adenine base in the rat.","volume":"47","author":"AKINTONWA","year":"1979","journal-title":"Toxicol. Appl. Pharmacol."},{"key":"10.1093\/jn\/118.6.780_bib5","doi-asserted-by":"crossref","first-page":"1340","DOI":"10.1093\/jn\/107.7.1340","article-title":"Report of the AIN Ad Hoc Committee on standards for nutritional studies.","volume":"107","author":"AMERICAN INSTITUTE OF NUTRITION","year":"1977","journal-title":"J. Nutr."},{"key":"10.1093\/jn\/118.6.780_bib6","doi-asserted-by":"crossref","first-page":"103","DOI":"10.1016\/S0378-4347(00)81276-1","article-title":"Simultaneous analysis of ATP, ADP, AMP and other purines in human erythrocytes by high-performance liquid chromatography.","volume":"181","author":"SCHWEINSBERG","year":"1980","journal-title":"J. Chromatogr."},{"key":"10.1093\/jn\/118.6.780_bib7","doi-asserted-by":"crossref","first-page":"11","DOI":"10.1016\/0003-2697(82)90616-9","article-title":"Quantitative determination of allantoin in biological fluids by reverse-phase high-pressure liquid chromatography.","volume":"123","author":"TIEMEYER","year":"1982","journal-title":"Anal. Biochem."},{"key":"10.1093\/jn\/118.6.780_bib8","doi-asserted-by":"crossref","first-page":"1","DOI":"10.2307\/3001478","article-title":"Multiple range and multiple F test","volume":"11","author":"DUNCAN","year":"1955","journal-title":"Biometrics"},{"key":"10.1093\/jn\/118.6.780_bib9","doi-asserted-by":"crossref","first-page":"323","DOI":"10.1016\/0014-4827(69)90512-6","article-title":"Changes in enzyme levels accompanying differentiation of intestinal epithelial cells.","volume":"58","author":"IMONDI","year":"1969","journal-title":"Exp. Cell Res."},{"key":"10.1093\/jn\/118.6.780_bib10","doi-asserted-by":"crossref","first-page":"1643","DOI":"10.1016\/S0021-9258(19)83755-9","article-title":"Studies in vitro of the digestion and absorption of purine ribonucleotides by the intestine.","volume":"237","author":"WILSON","year":"1962","journal-title":"J. Biol. Chem."},{"key":"10.1093\/jn\/118.6.780_bib11","doi-asserted-by":"crossref","first-page":"753","DOI":"10.1093\/jn\/114.4.753","article-title":"Absorption and metabolism of adenine, adenosine 5\u2019-monophosphate, adenosine and hypoxanthine by the isolated vascular perfused rat small intestine.","volume":"114","author":"SALATI","year":"1984","journal-title":"J. Nutr."},{"key":"10.1093\/jn\/118.6.780_bib12","doi-asserted-by":"crossref","first-page":"20","DOI":"10.1016\/S0022-3565(25)07684-0","article-title":"Adenine intoxication in relation to in vivo formation and deposition of 2-8-dioxyadenine in renal tubules.","volume":"104","author":"PHILIPS","year":"1952","journal-title":"J. Pharmacol. Exp. Ther."},{"key":"10.1093\/jn\/118.6.780_bib13","doi-asserted-by":"crossref","first-page":"1044","DOI":"10.1093\/jn\/107.6.1044","article-title":"Effects of dietary protein, adenine and allopurinol on growth and metabolism of rats.","volume":"107","author":"STORY","year":"1977","journal-title":"J. Nutr."},{"key":"10.1093\/jn\/118.6.780_bib14","doi-asserted-by":"crossref","first-page":"246","DOI":"10.1111\/j.1600-0773.1973.tb01468.x","article-title":"Adenine toxicity: a three week intravenous study in dogs.","volume":"32","author":"LINBLAD","year":"1973","journal-title":"Acta Pharmacol. Toxicol."},{"key":"10.1093\/jn\/118.6.780_bib15","doi-asserted-by":"crossref","first-page":"358","DOI":"10.1046\/j.1537-2995.1977.17477216864.x","article-title":"Formation of oxyadenine metabolites in the rabbit after intravenous administration of adenine.","volume":"17","author":"BARTLETT","year":"1977","journal-title":"Transfusion"},{"key":"10.1093\/jn\/118.6.780_bib16","doi-asserted-by":"crossref","first-page":"435","DOI":"10.1093\/jn\/106.3.435","article-title":"Levels of purines in foods and their metabolic effects in rats.","volume":"106","author":"CLIFFORD","year":"1976","journal-title":"J. Nutr."},{"key":"10.1093\/jn\/118.6.780_bib17","doi-asserted-by":"crossref","first-page":"1064","DOI":"10.1111\/j.1365-2621.1980.tb07516.x","article-title":"Evaluation of four purine compounds in poultry products.","volume":"45","author":"YOUNG","year":"1980","journal-title":"J. Food Sci."},{"key":"10.1093\/jn\/118.6.780_bib18","doi-asserted-by":"crossref","first-page":"1810","DOI":"10.3382\/ps.0621810","article-title":"Further studies on the composition of commercially prepared mechanically deboned poultry meat.","volume":"62","author":"HAMM","year":"1983","journal-title":"Poult. Sci."},{"key":"10.1093\/jn\/118.6.780_bib19","first-page":"1317","article-title":"Contents of free adenine in soybeans from several countries.","author":"YOKOZAWA","year":"1986","journal-title":"Agrie. Biol. Chem."},{"key":"10.1093\/jn\/118.6.780_bib20","doi-asserted-by":"crossref","first-page":"1374","DOI":"10.1111\/j.1365-2621.1982.tb07689.x","article-title":"Purine content of raw and roasted chicken broiler meat.","volume":"47","author":"YOUNG","year":"1982","journal-title":"J. Food Sci."},{"key":"10.1093\/jn\/118.6.780_bib21","doi-asserted-by":"crossref","first-page":"315","DOI":"10.1111\/j.1365-2621.1983.tb14868.x","article-title":"Effect of stewing on purine content of broiler tissues.","volume":"48","author":"YOUNG","year":"1983","journal-title":"J. Food Sci."}],"container-title":["The Journal of Nutrition"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0022316622169476?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0022316622169476?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/academic.oup.com\/jn\/article-pdf\/118\/6\/780\/23986296\/jn1180060780.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,6,29]],"date-time":"2025-06-29T11:14:06Z","timestamp":1751195646000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0022316622169476"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1988,6]]},"references-count":21,"journal-issue":{"issue":"6","published-print":{"date-parts":[[1988,6]]}},"alternative-id":["S0022316622169476"],"URL":"https:\/\/doi.org\/10.1093\/jn\/118.6.780","relation":{},"ISSN":["0022-3166"],"issn-type":[{"value":"0022-3166","type":"print"}],"subject":[],"published":{"date-parts":[[1988,6]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Differences in Uricogenic Effects of Dietary Purine Bases, Nucleosides and Nucleotides in Rats","name":"articletitle","label":"Article Title"},{"value":"The Journal of Nutrition","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1093\/jn\/118.6.780","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 1988 American Society for Nutrition. Published by Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}]}}