{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,4]],"date-time":"2026-08-04T04:22:06Z","timestamp":1785817326250,"version":"3.56.0"},"reference-count":21,"publisher":"Elsevier BV","issue":"10","license":[{"start":{"date-parts":[[1990,10,1]],"date-time":"1990-10-01T00:00:00Z","timestamp":654739200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["The Journal of Nutrition"],"published-print":{"date-parts":[[1990,10]]},"DOI":"10.1093\/jn\/120.10.1140","type":"journal-article","created":{"date-parts":[[2018,1,5]],"date-time":"2018-01-05T15:31:12Z","timestamp":1515166272000},"page":"1140-1147","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":18,"title":["Effect of Vitamin C Depletion on Serum Cholesterol and Lipoprotein Levels in ODS (od\/od) Rats Unable to Synthesize Ascorbic Acid"],"prefix":"10.1016","volume":"120","author":[{"given":"Kiyohisa","family":"Uchida","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yasuharu","family":"Nomura","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Haruto","family":"Takase","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Takenobu","family":"Tasaki","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shujiro","family":"Seo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yoshiyuki","family":"Hayashi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nozomu","family":"Takeuchi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1093\/jn\/120.10.1140_bib1","first-page":"374","article-title":"Osteogenic disorder rats.","volume":"29","author":"MAKINO","year":"1980","journal-title":"Exp. Anim."},{"key":"10.1093\/jn\/120.10.1140_bib2","doi-asserted-by":"crossref","first-page":"359","DOI":"10.1007\/BF01952551","article-title":"A rat mutant unable to synthesize vitamin C.","volume":"40","author":"MIZUSHIMA","year":"1984","journal-title":"Experientia"},{"key":"10.1093\/jn\/120.10.1140_bib3","doi-asserted-by":"crossref","first-page":"410","DOI":"10.1111\/j.1749-6632.1975.tb29299.x","article-title":"Ascorbic acid in cholesterol and bile acid metabolism.","volume":"258","author":"GINTER","year":"1975","journal-title":"Ann. N.Y. Acad. Sci."},{"key":"10.1093\/jn\/120.10.1140_bib4","doi-asserted-by":"crossref","first-page":"167","DOI":"10.1016\/B978-0-12-024916-9.50009-3","article-title":"Marginal vitamin C deficiency, lipid metabolism atherogenesis.","volume":"16","author":"GINTER","year":"1978","journal-title":"Adv. Lipid Res."},{"key":"10.1093\/jn\/120.10.1140_bib5","doi-asserted-by":"crossref","first-page":"201","DOI":"10.3177\/jnsv.22.201","article-title":"Fundamental studies on physiological and pharmacological actions of L-ascorbate 2-sulfate. I. On the hypolipidemic effects.","volume":"22","author":"HAYASHI","year":"1976","journal-title":"J. Nutr. Sci. Vitaminol."},{"key":"10.1093\/jn\/120.10.1140_bib6","first-page":"105","article-title":"Vitamins and lipid metabolism.","volume":"4","author":"FIDANZA","year":"1982","journal-title":"Acta Vitaminol. Enzymol."},{"key":"10.1093\/jn\/120.10.1140_bib7","doi-asserted-by":"crossref","first-page":"1036","DOI":"10.1093\/jn\/117.6.1036","article-title":"Effect of dietary ascorbic acid, cholesterol and PCB on cholesterol concentrations in serum and liver in a rat mutant unable to synthesize ascorbic acid.","volume":"117","author":"HORIO","year":"1987","journal-title":"J. Nutr."},{"key":"10.1093\/jn\/120.10.1140_bib8","doi-asserted-by":"crossref","first-page":"35","DOI":"10.3177\/jnsv.34.35","article-title":"Cholesterol metabolism in inherently scorbutic rats (ODS rats).","volume":"34","author":"KONO","year":"1988","journal-title":"J. Nutr. Sci. Vitaminol."},{"key":"10.1093\/jn\/120.10.1140_bib9","doi-asserted-by":"crossref","first-page":"1630","DOI":"10.1093\/jn\/115.12.1630","article-title":"Requirement for ascorbic acid in a rat mutant unable to synthesize ascorbic acid.","volume":"115","author":"HORIO","year":"1985","journal-title":"J. Nutr."},{"key":"10.1093\/jn\/120.10.1140_bib10","doi-asserted-by":"crossref","first-page":"1350","DOI":"10.1093\/clinchem\/19.12.1350","article-title":"Preparation and properties of a cholesterol oxidase from Nocardia sp. and its application to the enzymatic assay of total cholesterol in serum.","volume":"19","author":"RICHMOND","year":"1973","journal-title":"Clin.Chem."},{"key":"10.1093\/jn\/120.10.1140_bib11","doi-asserted-by":"crossref","first-page":"420","DOI":"10.1093\/clinchem\/21.3.420","article-title":"Mechanized enzymatic determination of triglycerides in serum.","volume":"21","author":"BUCOLO","year":"1975","journal-title":"Clin. Chem."},{"key":"10.1093\/jn\/120.10.1140_bib12","doi-asserted-by":"crossref","first-page":"93","DOI":"10.1016\/0009-8981(77)90465-X","article-title":"A new enzymatic method for the determination of serum choline-containing phospholipids.","volume":"79","author":"TAKAYAMA","year":"1977","journal-title":"Clin. Chim. Acta"},{"key":"10.1093\/jn\/120.10.1140_bib13","doi-asserted-by":"crossref","first-page":"1206","DOI":"10.1016\/S0022-2275(20)38059-7","article-title":"Separation and quantitation of subclasses of human plasma high density lipoproteins by a simple precipitation procedure.","volume":"23","author":"GIDEZ","year":"1982","journal-title":"J. Lipid Res."},{"key":"10.1093\/jn\/120.10.1140_bib14","doi-asserted-by":"crossref","first-page":"1345","DOI":"10.1172\/JCI103182","article-title":"Thedistribution and chemical composition of ultracentrifugally separated lipoproteins in human serum.","volume":"34","author":"HAVEL","year":"1955","journal-title":"J. Clin Invest."},{"key":"10.1093\/jn\/120.10.1140_bib15","doi-asserted-by":"crossref","first-page":"265","DOI":"10.1016\/S0021-9258(19)52451-6","article-title":"Protein measurement with Folin phenol reagent.","volume":"193","author":"LOWRY","year":"1951","journal-title":"J. Biol. Chem."},{"key":"10.1093\/jn\/120.10.1140_bib16","doi-asserted-by":"crossref","first-page":"497","DOI":"10.1016\/S0021-9258(18)64849-5","article-title":"A simple method for the isolation and purification of total lipids from animal tissues.","volume":"226","author":"FOLCH","year":"1957","journal-title":"J. Biol. Chem."},{"key":"10.1093\/jn\/120.10.1140_bib17","doi-asserted-by":"crossref","first-page":"353","DOI":"10.1007\/BF02533113","article-title":"Esterification of cholesterol and hydrolysis of cholesteryl ester in alcohol induced fatty liver of rats.","volume":"9","author":"TAKEUCHI","year":"1974","journal-title":"Lipids"},{"key":"10.1093\/jn\/120.10.1140_bib18","doi-asserted-by":"crossref","first-page":"187","DOI":"10.1093\/oxfordjournals.jbchem.a132724","article-title":"Effects of cholic acid, chenodeoxycholic acid, and their related bile acids on cholesterol, phospholipid, and bile acid levels in serum, liver, bile andfeces of rats.","volume":"87","author":"UCHIDA","year":"1980","journal-title":"J. Biochem."},{"key":"10.1093\/jn\/120.10.1140_bib19","doi-asserted-by":"crossref","first-page":"346","DOI":"10.1248\/bpb1978.6.346","article-title":"Effects of sodium ursodeoxycholate, hyo-deaxycholate and dehydrocholate on cholesterol and bile acid metabolism in rats.","volume":"6","author":"UCHIDA","year":"1983","journal-title":"J. Pharmacabio-Dyn."},{"key":"10.1093\/jn\/120.10.1140_bib20","doi-asserted-by":"crossref","first-page":"573","DOI":"10.1016\/S0022-2275(20)36863-2","article-title":"Regulatory effects of sterols and bile acids on hepatic 3-hydroxy-3-methylglutaryl CoA reductase and cholesterol 7\u03b1-hydroxylase in the rat.","volume":"14","author":"SHEFER","year":"1973","journal-title":"J. Lipid Res."},{"key":"10.1093\/jn\/120.10.1140_bib21","doi-asserted-by":"crossref","first-page":"1161","DOI":"10.1016\/S0022-2275(20)38276-6","article-title":"Regulation of bile acid synthesis. III. Correlation between biliary bile salt hydrophobicity index and the activities of enzymes regulating cholesterol and bile acid synthesis in the rat.","volume":"30","author":"HEUMAN","year":"1989","journal-title":"J. Lipid Res."}],"container-title":["The Journal of Nutrition"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0022316622174250?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0022316622174250?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/academic.oup.com\/jn\/article-pdf\/120\/10\/1140\/23986477\/jn1200101140.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,6,12]],"date-time":"2023-06-12T13:43:43Z","timestamp":1686577423000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0022316622174250"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1990,10]]},"references-count":21,"journal-issue":{"issue":"10","published-print":{"date-parts":[[1990,10]]}},"alternative-id":["S0022316622174250"],"URL":"https:\/\/doi.org\/10.1093\/jn\/120.10.1140","relation":{},"ISSN":["0022-3166"],"issn-type":[{"value":"0022-3166","type":"print"}],"subject":[],"published":{"date-parts":[[1990,10]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Effect of Vitamin C Depletion on Serum Cholesterol and Lipoprotein Levels in ODS (od\/od) Rats Unable to Synthesize Ascorbic Acid","name":"articletitle","label":"Article Title"},{"value":"The Journal of Nutrition","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1093\/jn\/120.10.1140","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 1990 American Society for Nutrition. Published by Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}]}}