{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,2]],"date-time":"2026-10-02T03:56:05Z","timestamp":1790913365994,"version":"4.1.0"},"reference-count":43,"publisher":"Elsevier BV","issue":"11","license":[{"start":{"date-parts":[[1992,11,1]],"date-time":"1992-11-01T00:00:00Z","timestamp":720576000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["The Journal of Nutrition"],"published-print":{"date-parts":[[1992,11]]},"DOI":"10.1093\/jn\/122.11.2144","type":"journal-article","created":{"date-parts":[[2018,1,5]],"date-time":"2018-01-05T15:35:16Z","timestamp":1515166516000},"page":"2144-2152","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":63,"title":["Expression of Retinoic Acid Nuclear Receptors and Tissue Transglutaminase Is Altered in Various Tissues of Rats Fed a Vitamin A-Deficient Diet"],"prefix":"10.1016","volume":"122","author":[{"given":"Ajit K.","family":"Verma","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alex","family":"Shoemaker","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ruby","family":"Simsiman","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mitchell","family":"Denning","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Richard D.","family":"Zachman","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1093\/jn\/122.11.2144_bib1","doi-asserted-by":"crossref","first-page":"1084","DOI":"10.1016\/S0022-2275(20)38760-5","article-title":"Effects of dietary retinoic acid on cellular retinol and retinoic acid binding protein levels in various rat tissues.","volume":"27","author":"Blaner","year":"1986","journal-title":"J. Lipid Res."},{"key":"10.1093\/jn\/122.11.2144_bib2","doi-asserted-by":"crossref","first-page":"850","DOI":"10.1038\/332850a0","article-title":"Identification of a second human retinoic acid receptor.","volume":"332","author":"Brand","year":"1988","journal-title":"Nature (Lond.)"},{"key":"10.1093\/jn\/122.11.2144_bib3","doi-asserted-by":"crossref","first-page":"145","DOI":"10.1002\/bies.950110508","article-title":"Morphogens in chick limb development.","volume":"11","author":"Brickell","year":"1989","journal-title":"Bioessays"},{"key":"10.1093\/jn\/122.11.2144_bib4","doi-asserted-by":"crossref","first-page":"293","DOI":"10.1002\/jcb.240390309","article-title":"Regulation of tissue transglutaminase gene expression as a molecular model for retinoid effects on proliferation and differentiation.","volume":"39","author":"Chiocca","year":"1989","journal-title":"J. Cell Biochem."},{"key":"10.1093\/jn\/122.11.2144_bib5","first-page":"156","article-title":"Single step method of RNA isolation by acid guanidinium thiocyanate phenol-chloroform extraction.","volume":"162","author":"Chomezynski","year":"1987","journal-title":"Anal. Biochem."},{"key":"10.1093\/jn\/122.11.2144_bib6","first-page":"2519","article-title":"Retinoic acid metabolism.","volume":"38","author":"DeLuca","year":"1979","journal-title":"Fed. Proc."},{"key":"10.1093\/jn\/122.11.2144_bib7","doi-asserted-by":"crossref","first-page":"2924","DOI":"10.1096\/fasebj.5.14.1661245","article-title":"Retinoids and their receptors in differentiation, embryogenesis, and neoplasia.","volume":"5","author":"DeLuca","year":"1991","journal-title":"FASEB J."},{"key":"10.1093\/jn\/122.11.2144_bib8","first-page":"13","article-title":"Vitamin A: a key nutrient for the maintenance of epithelial differentiation.","volume":"7","author":"DeLuca","year":"1985","journal-title":"Acta Vitaminol. Enzymol."},{"key":"10.1093\/jn\/122.11.2144_bib9","doi-asserted-by":"crossref","first-page":"344","DOI":"10.1016\/S0006-291X(05)81241-0","article-title":"Involvement of retinoic acid nuclear receptors in retinoic acid-induced tissue transglutaminase gene expression in rat tracheal 2C5 cells.","volume":"175","author":"Denning","year":"1991","journal-title":"Biochem. Biophys. Res. Comm."},{"key":"10.1093\/jn\/122.11.2144_bib10","doi-asserted-by":"crossref","first-page":"177","DOI":"10.1038\/343177a0","article-title":"Identification of a retinoic acid responsive element in the retinoic acid receptor beta gene.","volume":"343","author":"de The","year":"1990","journal-title":"Nature (Lond.)"},{"key":"10.1093\/jn\/122.11.2144_bib11","first-page":"1638","article-title":"Retinoic acid response element in the human alcohol dehydrogenase gene ADH3: implications for regulation of retinic acid synthesis.","volume":"11","author":"Duester","year":"1991","journal-title":"Mol. Cell. Biol."},{"key":"10.1093\/jn\/122.11.2144_bib12","doi-asserted-by":"crossref","first-page":"5761","DOI":"10.1073\/pnas.82.17.5761","article-title":"Nerve growth factor rapidly induces ornithine decarboxylase mRNA in PC 12 rat pheochromocytoma cells.","volume":"82","author":"Feinstein","year":"1985","journal-title":"Proc. Natl. Acad. Sci. U.S.A."},{"key":"10.1093\/jn\/122.11.2144_bib13","doi-asserted-by":"crossref","first-page":"1431","DOI":"10.1093\/nar\/13.5.1431","article-title":"Various rat adult tissues express only one major mRNA species from the glyceraldehyde-3-phosphate-dehydrogenase multigenic family.","volume":"13","author":"Fort","year":"1985","journal-title":"Nucleic Acids Res."},{"key":"10.1093\/jn\/122.11.2144_bib14","doi-asserted-by":"crossref","first-page":"11098","DOI":"10.1016\/S0021-9258(19)38562-X","article-title":"Regulation of transglutaminase type II transforming growth factor-B1 in normal and transformed human epidermal keratinocytes.","volume":"265","author":"George","year":"1990","journal-title":"J. Biol. Chem."},{"key":"10.1093\/jn\/122.11.2144_bib15","first-page":"2716","article-title":"Vitamin A metabolism.","volume":"38","author":"Goodman","year":"1979","journal-title":"Fed. Proc."},{"key":"10.1093\/jn\/122.11.2144_bib16","doi-asserted-by":"crossref","first-page":"8272","DOI":"10.1073\/pnas.88.18.8272","article-title":"Retinoic acid affects the expression of nuclear retinoic acid receptors in tissues of retinol-deficient rats.","volume":"88","author":"Haq","year":"1991","journal-title":"Proc. Natl. Acad. Sci. U.S.A."},{"key":"10.1093\/jn\/122.11.2144_bib17","doi-asserted-by":"crossref","first-page":"1727","DOI":"10.1210\/mend-4-11-1727","article-title":"A retinoic acid receptor-specific element controls the retinoic acid receptor-\u03b2 promoter.","volume":"4","author":"Hoffmann","year":"1990","journal-title":"Mol. Endocrinol."},{"key":"10.1093\/jn\/122.11.2144_bib18","doi-asserted-by":"crossref","first-page":"837","DOI":"10.1210\/mend-4-6-837","article-title":"A functional retinoic acid receptor encoded by the gene on human chromosome 12.","volume":"4","author":"Ishikawa","year":"1990","journal-title":"Mol. Endocrinol."},{"key":"10.1093\/jn\/122.11.2144_bib19","doi-asserted-by":"crossref","first-page":"622","DOI":"10.1016\/0014-4827(89)90264-4","article-title":"Keratin 13 expression is linked to squamous differentiation in rabbit tracheal epithelial cells and down-regulated by retinoic acid.","volume":"182","author":"Jetten","year":"1989","journal-title":"Exp. Cell Res."},{"key":"10.1093\/jn\/122.11.2144_bib20","doi-asserted-by":"crossref","first-page":"1541","DOI":"10.1093\/nar\/7.6.1541","article-title":"Determination of nucleic acid sequence homologies and relative concentrations by a dot hybridization procedure.","volume":"7","author":"Kafatos","year":"1979","journal-title":"Nucleic Acids Res."},{"key":"10.1093\/jn\/122.11.2144_bib21","doi-asserted-by":"crossref","first-page":"4832","DOI":"10.1016\/S0021-9258(18)89146-3","article-title":"Influence of retinoid nutritional status on cellular retinol- and cellular retinoic acid-binding protein concentrations in various rat tissues.","volume":"260","author":"Kato","year":"1985","journal-title":"J. Biol. Chem."},{"key":"10.1093\/jn\/122.11.2144_bib22","doi-asserted-by":"crossref","first-page":"365","DOI":"10.1016\/S0021-9258(19)75936-5","article-title":"Vitamin A deficiency alters genomic expression for fibronectin in liver and hepatocytes.","volume":"262","author":"Kim","year":"1987","journal-title":"I. Biol. Chem."},{"key":"10.1093\/jn\/122.11.2144_bib23","doi-asserted-by":"crossref","first-page":"5310","DOI":"10.1073\/pnas.86.14.5310","article-title":"A third human retinoic acid receptor, hRAR-gamma.","volume":"86","author":"Krust","year":"1989","journal-title":"Proc. Natl. Acad. Sci. U.S.A."},{"key":"10.1093\/jn\/122.11.2144_bib24","doi-asserted-by":"crossref","first-page":"1140","DOI":"10.1093\/jn\/104.9.1140","article-title":"Induction of rapid, synchronous vitamin A deficiency in the rat.","volume":"104","author":"Lamb","year":"1974","journal-title":"J. Nutr."},{"key":"10.1093\/jn\/122.11.2144_bib25","first-page":"74","article-title":"Modulation of tissue and epidermal transglutaminase in mouse epidermal cells after treatment with 12-O-tetradecanoylphorbol-13-acetate\/or retinoic acid in vivo and in culture.","volume":"48","author":"Lichti","year":"1988","journal-title":"Cancer Res."},{"key":"10.1093\/jn\/122.11.2144_bib26","doi-asserted-by":"crossref","first-page":"224","DOI":"10.1038\/345224a0","article-title":"Nuclear receptor that identifies a novel retinoic acid response pathway.","volume":"345","author":"Mangelsdorf","year":"1990","journal-title":"Nature (Lond.)"},{"key":"10.1093\/jn\/122.11.2144_bib27","first-page":"1435","article-title":"Vitamin A and lung cancer.","volume":"62","author":"Mettlin","year":"1979","journal-title":"J. Natl. Cancer Inst."},{"key":"10.1093\/jn\/122.11.2144_bib28","doi-asserted-by":"crossref","first-page":"107","DOI":"10.1080\/01635588609513883","article-title":"Dietary vitamin A and cancer\u2014a multisite case-control study.","volume":"8","author":"Middleton","year":"1986","journal-title":"Nutr. Cancer"},{"key":"10.1093\/jn\/122.11.2144_bib29","doi-asserted-by":"crossref","first-page":"20065","DOI":"10.1016\/S0021-9258(17)30466-0","article-title":"Mapping of a retinoic acid responsive element in the promoter region of the complement factor H gene.","volume":"265","author":"Munox-Canoves","year":"1990","journal-title":"J. Biol. Chem."},{"key":"10.1093\/jn\/122.11.2144_bib30","first-page":"1379","article-title":"Effect of vitamin A deficiency on rat colon carcinogenesis by N-methyl-N\u2019-nitro-N-nitrosoguanidine.","volume":"36","author":"Narisawa","year":"1976","journal-title":"Cancer Res."},{"key":"10.1093\/jn\/122.11.2144_bib31","doi-asserted-by":"crossref","first-page":"163","DOI":"10.1016\/0014-4827(91)90512-S","article-title":"Expression of nuclear retinoic acid receptors in normal tracheobronchial cells and in lung carcinoma cells.","volume":"195","author":"Nervi","year":"1991","journal-title":"Exp. Cell Res."},{"key":"10.1093\/jn\/122.11.2144_bib32","doi-asserted-by":"crossref","first-page":"351","DOI":"10.1002\/ijc.2910170311","article-title":"The influence of vitamin A on the susceptibility of the rat lung to 3-methylcholanthrene.","volume":"17","author":"Nettesheim","year":"1976","journal-title":"Int. J. Cancer"},{"key":"10.1093\/jn\/122.11.2144_bib33","doi-asserted-by":"crossref","first-page":"444","DOI":"10.1038\/330444a0","article-title":"A human retinoic acid receptor which belongs to the family of nuclear receptors.","volume":"330","author":"Petkovich","year":"1987","journal-title":"Nature (Lond.)"},{"key":"10.1093\/jn\/122.11.2144_bib34","doi-asserted-by":"crossref","first-page":"821","DOI":"10.1016\/S0022-2275(20)42781-6","article-title":"Cellular retinol-binding protein messenger RNA levels in normal and retinoid-deficient rats.","volume":"31","author":"Rajan","year":"1990","journal-title":"J. Lipid Res."},{"key":"10.1093\/jn\/122.11.2144_bib35","doi-asserted-by":"crossref","first-page":"497","DOI":"10.1016\/0092-8674(90)90531-I","article-title":"Jun-fos and receptors for vitamins A and D recognize a common response element in the human osteocalcin gene.","volume":"61","author":"Schule","year":"1990","journal-title":"Cell"},{"key":"10.1093\/jn\/122.11.2144_bib36","first-page":"578","article-title":"Purification of keratinocyte transglutaminase and its expression during squamous differentiation.","volume":"92","author":"Thacher","year":"1989","journal-title":"J. Invest. Dermatol."},{"key":"10.1093\/jn\/122.11.2144_bib37","doi-asserted-by":"crossref","first-page":"5201","DOI":"10.1073\/pnas.77.9.5201","article-title":"Hybridization of denatured RNA and small DNA fragments transferred to nitrocellulose.","volume":"77","author":"Thomas","year":"1980","journal-title":"Proc. Natl. Acad. Sci. U.S.A."},{"key":"10.1093\/jn\/122.11.2144_bib38","doi-asserted-by":"crossref","first-page":"9099","DOI":"10.1073\/pnas.86.23.9099","article-title":"A retinoic acid-responsive element is present in the 5'-flanking region of the laminin B1 gene.","volume":"86","author":"Vasios","year":"1989","journal-title":"Proc. Natl. Acad. Sci. U.S.A."},{"key":"10.1093\/jn\/122.11.2144_bib39","doi-asserted-by":"crossref","first-page":"284","DOI":"10.1016\/0955-2863(90)90061-O","article-title":"Recent progress in vitamin A research: nuclear retinoic acid receptors and their interaction with gene elements.","volume":"1","author":"Wolf","year":"1990","journal-title":"J. Nutr. Biochem."},{"key":"10.1093\/jn\/122.11.2144_bib40","doi-asserted-by":"crossref","first-page":"187","DOI":"10.1093\/jn\/121.2.187","article-title":"Intramuscular relative dose response (RDR) determination of liver vitamin A stores in rats.","volume":"121","author":"Zachman","year":"1991","journal-title":"J. Nutr."},{"key":"10.1093\/jn\/122.11.2144_bib41","first-page":"113","article-title":"Some effects of vitamin A deficiency on the isolated rat lung alveolar type II cell.","volume":"62","author":"Zachman","year":"1992","journal-title":"Inter. J. Vitam. Nutr. Res."},{"key":"10.1093\/jn\/122.11.2144_bib42","doi-asserted-by":"crossref","first-page":"714","DOI":"10.1038\/339714a0","article-title":"Cloning of murine alpha and beta retinoic acid receptors and a novel receptor gamma predominately expressed in skin.","volume":"339","author":"Zelent","year":"1989","journal-title":"Nature (Lond.)"},{"key":"10.1093\/jn\/122.11.2144_bib43","first-page":"3495","article-title":"Effect of moderate vitamin A supplementation and lack of dietary vitamin A on the development of mammary tumors in female rats treated with low carcinogenic dose levels of 7,12-dimethylbenz(a)anthracene.","volume":"46","author":"Zile","year":"1986","journal-title":"Cancer Res."}],"container-title":["The Journal of Nutrition"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S002231662304782X?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S002231662304782X?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/academic.oup.com\/jn\/article-pdf\/122\/11\/2144\/23985447\/jn1220112144.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,6,12]],"date-time":"2023-06-12T17:31:24Z","timestamp":1686591084000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S002231662304782X"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1992,11]]},"references-count":43,"journal-issue":{"issue":"11","published-print":{"date-parts":[[1992,11]]}},"alternative-id":["S002231662304782X"],"URL":"https:\/\/doi.org\/10.1093\/jn\/122.11.2144","relation":{},"ISSN":["0022-3166"],"issn-type":[{"value":"0022-3166","type":"print"}],"subject":[],"published":{"date-parts":[[1992,11]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Expression of Retinoic Acid Nuclear Receptors and Tissue Transglutaminase Is Altered in Various Tissues of Rats Fed a Vitamin A-Deficient Diet","name":"articletitle","label":"Article Title"},{"value":"The Journal of Nutrition","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1093\/jn\/122.11.2144","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 1992 American Institute of Nutrition. Published by Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}]}}