{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,16]],"date-time":"2026-04-16T18:25:08Z","timestamp":1776363908801,"version":"3.51.2"},"reference-count":31,"publisher":"Elsevier BV","issue":"3","license":[{"start":{"date-parts":[[1995,3,1]],"date-time":"1995-03-01T00:00:00Z","timestamp":794016000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[1995,3,1]],"date-time":"1995-03-01T00:00:00Z","timestamp":794016000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["The Journal of Nutrition"],"published-print":{"date-parts":[[1995,3]]},"DOI":"10.1093\/jn\/125.3.474","type":"journal-article","created":{"date-parts":[[2025,2,12]],"date-time":"2025-02-12T03:54:18Z","timestamp":1739332458000},"page":"474-484","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":6,"title":["Iron Status Alters Murine Systemic Lupus Erythematosus"],"prefix":"10.1016","volume":"125","author":[{"given":"Lorene M.","family":"Leiter","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kenneth R.","family":"Reuhl","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"suffix":"Jr.","given":"Stanley P.","family":"Racis","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Adria R.","family":"Sherman","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1093\/jn\/125.3.474_bib1","doi-asserted-by":"crossref","first-page":"327","DOI":"10.1136\/ard.46.4.327","article-title":"Effect of iron chelators on inflammatory joint disease.","volume":"46","author":"Andrews","year":"1987","journal-title":"Ann. Rheum. Dis"},{"key":"10.1093\/jn\/125.3.474_bib2","first-page":"308","article-title":"Nutritional factors and autoimmunity.","volume":"128","author":"Beach","year":"1982","journal-title":"II. Prolongation of survival in zinc-deprived NZB\/W mice. J. Immuno"},{"key":"10.1093\/jn\/125.3.474_bib3","doi-asserted-by":"crossref","first-page":"89","DOI":"10.1136\/ard.42.1.89","article-title":"Effect of a specific iron chelating agent on animal models of inflammation.","volume":"42","author":"Blake","year":"1983","journal-title":"Ann. Rheum. Dis"},{"key":"10.1093\/jn\/125.3.474_bib4","series-title":"In: Handbook of Animal Models for the Rheumatic Diseases","first-page":"140","article-title":"The utility of the MRL\/1 mouse for detecting anti-arthritic drugs.","author":"Boer","year":"1988"},{"key":"10.1093\/jn\/125.3.474_bib5","doi-asserted-by":"crossref","first-page":"1532","DOI":"10.1084\/jem.160.5.1532","article-title":"Inhibition of autoimmune neuropathological process by treatment with an iron-chelating agent.","volume":"160","author":"Bowern","year":"1984","journal-title":"J. Exp. Med"},{"key":"10.1093\/jn\/125.3.474_bib6","doi-asserted-by":"crossref","first-page":"813","DOI":"10.1038\/ki.1986.260","article-title":"Hydroxyl radical mediation of immune renal injury by desferoxamine.","volume":"30","author":"Boyce","year":"1986","journal-title":"Kidney Int"},{"key":"10.1093\/jn\/125.3.474_bib7","first-page":"361","article-title":"Rapid determination of urea nitrogen in serum or plasma without deproteinization.","volume":"33","author":"Crocker","year":"1967","journal-title":"Am. J. Med. Techno"},{"key":"10.1093\/jn\/125.3.474_bib8","doi-asserted-by":"crossref","first-page":"1500","DOI":"10.1073\/pnas.75.3.1500","article-title":"Influence of dietary restriction on immunologic function and renal disease in (NZB x NZW) Fl mice.","volume":"75","author":"Femandes","year":"1978","journal-title":"Proc. Natl. Acad. Sci. U.S.A"},{"key":"10.1093\/jn\/125.3.474_bib9","doi-asserted-by":"crossref","first-page":"291","DOI":"10.1016\/0014-5793(86)80626-3","article-title":"Iron promoters of the Fenton reaction and lipid peroxidation can be released from haemoglobin by peroxides.","volume":"201","author":"Gutteridge","year":"1986","journal-title":"FEBS Lett"},{"key":"10.1093\/jn\/125.3.474_bib10","doi-asserted-by":"crossref","first-page":"332","DOI":"10.1098\/rspa.1934.0221","article-title":"The catalytic decomposition of hydrogen peroxide by iron salts.","volume":"147","author":"Haber","year":"1934","journal-title":"Proc. R. Soc. London Ser. A"},{"key":"10.1093\/jn\/125.3.474_bib11","series-title":"In: Iron and Human Disease","first-page":"209","article-title":"Iron and damage to biomolecules.","author":"Halliwell","year":"1992"},{"key":"10.1093\/jn\/125.3.474_bib12","doi-asserted-by":"crossref","first-page":"305","DOI":"10.1016\/0009-8981(73)90466-X","article-title":"Determination of serum creatinine by a direct colorimetric method.","volume":"43","author":"Heinegard","year":"1973","journal-title":"Clin. Chim. Acta"},{"key":"10.1093\/jn\/125.3.474_bib13","first-page":"476","article-title":"Prevention of glomerulonephritis and prolonged survival in New Zealand Black\/New Zealand White Fi Hybrid mice fed an essential fatty acid-deficient diet.","volume":"67","author":"Hurd","year":"1981","journal-title":"J. Clin."},{"key":"10.1093\/jn\/125.3.474_bib14","doi-asserted-by":"crossref","first-page":"511","DOI":"10.1016\/S0271-5317(84)80111-6","article-title":"Phagocytosis and lysozyme activity in granulocytes from iron-deficient rat dams and pups.","volume":"4","author":"Kochanowski","year":"1984","journal-title":"Nutr. Res"},{"key":"10.1093\/jn\/125.3.474_bib15","unstructured":"Koffler, D. (1987) Immunology of systemic lupus erythematosus and related rheumatic diseases. Clinical Symposia, Ciba-Geigy, Vol. 39, No. 2, pp. 1-36."},{"key":"10.1093\/jn\/125.3.474_bib16","series-title":"In: The Clinical Management of Systemic Lupus Erythematosus","first-page":"29","article-title":"Immunopathogenesis of tissue injury.","author":"Koffler","year":"1983"},{"key":"10.1093\/jn\/125.3.474_bib17","doi-asserted-by":"crossref","first-page":"5831","DOI":"10.1073\/pnas.81.18.5831","article-title":"Influence of early or late dietary restriction on life span and immunological parameters in MRL\/MP-lpr\/lpr mice.","volume":"81","author":"Kubo","year":"1984","journal-title":"Proc. Natl. Acad. Sci. U.S.A"},{"key":"10.1093\/jn\/125.3.474_bib18","doi-asserted-by":"crossref","first-page":"170","DOI":"10.1093\/jn\/117.1.170","article-title":"Macrophage function as studied by the clearance of 125I labelled polyvinylpyrollidone in iron deficiency and iron replete mice.","volume":"117","author":"Kuvibidila","year":"1987","journal-title":"J. Nutr"},{"key":"10.1093\/jn\/125.3.474_bib19","first-page":"1","article-title":"Iron and Human Disease, pp.","author":"Lauffer","year":"1992"},{"key":"10.1093\/jn\/125.3.474_bib20","doi-asserted-by":"crossref","first-page":"415","DOI":"10.1126\/science.7071589","article-title":"Systemic lupus erythematosus-like syndrome in monkeys fed alfalfa spouts: Role of a nonprotein amino acid.","volume":"216","author":"Malinow","year":"1982","journal-title":"Science"},{"key":"10.1093\/jn\/125.3.474_bib21","first-page":"3857","article-title":"Dietary fat and immune function.","volume":"135","author":"Morrow","year":"1985","journal-title":"I. Antibody responses, lymphocyte and accessory cell function in (NZB x NZW) Fi mice. J. Immunol."},{"key":"10.1093\/jn\/125.3.474_bib22","series-title":"Induction by mutant gene lpr, and acceleration by a male-associated factor in strain BXSB mice. In: Genetic Control of Autoimmune Disease","first-page":"207","article-title":"Autoimmunity and lym- phoproliferation.","author":"Murphy","year":"1978"},{"key":"10.1093\/jn\/125.3.474_bib23","article-title":"Nutrient Requirements for Laboratory Animals","year":"1985"},{"key":"10.1093\/jn\/125.3.474_bib24","article-title":"Guide for the Care and Use of Laboratory Animals.","year":"1995"},{"key":"10.1093\/jn\/125.3.474_bib25","first-page":"346","article-title":"A simplification of the protein assay method of Lowry et al.","volume":"83","author":"Peterson","year":"1977","journal-title":"which is more generally applicable. Anal. Biochem."},{"key":"10.1093\/jn\/125.3.474_bib26","doi-asserted-by":"crossref","first-page":"993","DOI":"10.1038\/ki.1989.83","article-title":"Physiological, and pathological aspects of circulating immune complexes.","volume":"35","author":"Schifferli","year":"1989","journal-title":"Kidney Int"},{"key":"10.1093\/jn\/125.3.474_bib27","series-title":"In: The Clinical Management of Systemic Lupus Erythematosus.","first-page":"9","article-title":"General symptomatology.","author":"Schur","year":"1983"},{"key":"10.1093\/jn\/125.3.474_bib28","article-title":"Principles and Procedures of Statistics, 2nd ed.","author":"Steel","year":"1980"},{"key":"10.1093\/jn\/125.3.474_bib29","series-title":"In: Systemic Lupus Erythematosus","first-page":"121","article-title":"Experimental murine SLE","author":"Theofilopoulos","year":"1987"},{"key":"10.1093\/jn\/125.3.474_bib30","doi-asserted-by":"crossref","first-page":"806","DOI":"10.1126\/science.161.3843.806","article-title":"Deoxyribonucleic acid antibody: A method to detect its primary interaction with deoxyribonucleic acid.","volume":"161","author":"Wold","year":"1968","journal-title":"Science"},{"key":"10.1093\/jn\/125.3.474_bib31","first-page":"3864","article-title":"Dietary fat and immune function, n.","volume":"135","author":"Yumara","year":"1985","journal-title":"Effects on immune complex nephritis in (NZB x NZW) Fi mice. J. Immuno"}],"container-title":["The Journal of Nutrition"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0022316623036568?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0022316623036568?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,2,12]],"date-time":"2025-02-12T11:21:54Z","timestamp":1739359314000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0022316623036568"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1995,3]]},"references-count":31,"journal-issue":{"issue":"3","published-print":{"date-parts":[[1995,3]]}},"alternative-id":["S0022316623036568"],"URL":"https:\/\/doi.org\/10.1093\/jn\/125.3.474","relation":{},"ISSN":["0022-3166"],"issn-type":[{"value":"0022-3166","type":"print"}],"subject":[],"published":{"date-parts":[[1995,3]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Iron Status Alters Murine Systemic Lupus Erythematosus","name":"articletitle","label":"Article Title"},{"value":"The Journal of Nutrition","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1093\/jn\/125.3.474","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 1995 American Society for Nutrition. Published by Elsevier Inc. All rights are reserved, including those for text and data mining, AI training, and similar technologies.","name":"copyright","label":"Copyright"}]}}