{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,5]],"date-time":"2026-10-05T17:36:40Z","timestamp":1791221800760,"version":"4.1.0"},"reference-count":71,"publisher":"Elsevier BV","issue":"4","license":[{"start":{"date-parts":[[2000,4,1]],"date-time":"2000-04-01T00:00:00Z","timestamp":954547200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2000,4,1]],"date-time":"2000-04-01T00:00:00Z","timestamp":954547200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2023,2,1]],"date-time":"2023-02-01T00:00:00Z","timestamp":1675209600000},"content-version":"vor","delay-in-days":8341,"URL":"http:\/\/www.elsevier.com\/open-access\/userlicense\/1.0\/"}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["The Journal of Nutrition"],"published-print":{"date-parts":[[2000,4]]},"DOI":"10.1093\/jn\/130.4.1016s","type":"journal-article","created":{"date-parts":[[2018,1,19]],"date-time":"2018-01-19T11:08:54Z","timestamp":1516360134000},"page":"1016S-1022S","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":338,"title":["Transport of Glutamate and Other Amino Acids at the Blood-Brain Barrier"],"prefix":"10.1016","volume":"130","author":[{"given":"Quentin R.","family":"Smith","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1093\/jn\/130.4.1016S_bib1","doi-asserted-by":"crossref","first-page":"430","DOI":"10.1016\/0888-7543(92)90431-Q","article-title":"The human cationic amino acid transporter (ATRC1): physical and genetic mapping to 13q12\u2013q14","volume":"12","author":"Albritton","year":"1992","journal-title":"Genomics"},{"key":"10.1093\/jn\/130.4.1016S_bib2","doi-asserted-by":"crossref","first-page":"659","DOI":"10.1016\/0092-8674(89)90134-7","article-title":"A putative murine ecotropic retrovirus receptor gene encodes a multiple membrane-spanning protein and confers susceptibility to virus infection","volume":"57","author":"Albritton","year":"1989","journal-title":"Cell"},{"key":"10.1093\/jn\/130.4.1016S_bib3","doi-asserted-by":"crossref","first-page":"151","DOI":"10.1016\/0165-3806(96)83495-X","article-title":"The entry of acidic amino acids into brain and CSF during development using in situ brain perfusion in the rat","volume":"90","author":"Al-Sarraf","year":"1995","journal-title":"Dev. Brain Res"},{"key":"10.1093\/jn\/130.4.1016S_bib4","doi-asserted-by":"crossref","first-page":"47","DOI":"10.1016\/S0165-3806(97)00075-8","article-title":"Acidic amino acid accumulation by rat choroid plexus during development","volume":"102","author":"Al-Sarraf","year":"1997","journal-title":"Dev. Brain Res"},{"key":"10.1093\/jn\/130.4.1016S_bib5","doi-asserted-by":"crossref","first-page":"127","DOI":"10.1016\/S0165-3806(97)00089-8","article-title":"Changes in the kinetics of the acidic amino acid brain and CSF uptake during development in the rat","volume":"102","author":"Al-Sarraf","year":"1997","journal-title":"Dev. Brain Res"},{"key":"10.1093\/jn\/130.4.1016S_bib6","doi-asserted-by":"crossref","first-page":"1220","DOI":"10.1111\/j.1471-4159.1988.tb10596.x","article-title":"Blood-brain barrier transport of 1-aminocyclohexanecarboxylic acid, a nonmetabolizable amino acid for in vivo studies of brain transport","volume":"50","author":"Aoyagi","year":"1988","journal-title":"J. Neurochem"},{"key":"10.1093\/jn\/130.4.1016S_bib7","doi-asserted-by":"crossref","first-page":"9","DOI":"10.1016\/0304-3940(96)12635-5","article-title":"Glutamate is transported across the rat blood-brain barrier by a sodium-independent system","volume":"210","author":"Benrabh","year":"1996","journal-title":"Neurosci. Lett"},{"key":"10.1093\/jn\/130.4.1016S_bib8","doi-asserted-by":"crossref","first-page":"5606","DOI":"10.1073\/pnas.89.12.5606","article-title":"Stimulation of system y+-like amino acid transport by the heavy chain of 4F2 surface antigen in Xenopus laevis oocytes","volume":"89","author":"Bertran","year":"1992","journal-title":"Proc. Natl. Acad. Sci. U.S.A"},{"key":"10.1093\/jn\/130.4.1016S_bib9","doi-asserted-by":"crossref","first-page":"225","DOI":"10.1126\/science.211586","article-title":"Polarity of the blood-brain barrier: neutral amino acid transport into isolated brain capillaries","volume":"202","author":"Betz","year":"1978","journal-title":"Science (Washington DC)"},{"key":"10.1093\/jn\/130.4.1016S_bib10","doi-asserted-by":"crossref","first-page":"12079","DOI":"10.1073\/pnas.96.21.12079","article-title":"Selective expression of the large neutral amino acid transporter at the blood-brain barrier","volume":"96","author":"Boado","year":"1999","journal-title":"Proc. Natl. Acad. Sci. USA"},{"key":"10.1093\/jn\/130.4.1016S_bib11","doi-asserted-by":"crossref","first-page":"337","DOI":"10.1016\/0006-8993(94)91309-9","article-title":"Effects of systemic or oral ad libitum monosodium glutamate administration on striatal glutamate release, as measured using microdialysis in freely moving rats","volume":"660","author":"Bogdanov","year":"1994","journal-title":"Brain Res"},{"key":"10.1093\/jn\/130.4.1016S_bib12","doi-asserted-by":"crossref","first-page":"863","DOI":"10.1042\/bj3120863","article-title":"The 4F2hc surface antigen is necessary for expression of L-like neutral amino acid transport activity in C6-BU-1 rat glioma cells: evidence from expression studies in Xenopus laevis oocytes","volume":"312","author":"Br\u00f6er","year":"1995","journal-title":"Biochem. J"},{"key":"10.1093\/jn\/130.4.1016S_bib13","doi-asserted-by":"crossref","first-page":"535","DOI":"10.1042\/bj3240535","article-title":"Expression of the surface antigen 4F2hc affects L-like neutral amino acid transport activity in mammalian cells","volume":"324","author":"Br\u00f6er","year":"1997","journal-title":"Biochem. J"},{"key":"10.1093\/jn\/130.4.1016S_bib14","doi-asserted-by":"crossref","first-page":"269","DOI":"10.1242\/jeb.200.2.269","article-title":"Molecular characterization of mammalian and insect amino acid transporters: implications for amino acid homeostasis","volume":"200","author":"Castagna","year":"1997","journal-title":"J. Exp. Biol"},{"key":"10.1093\/jn\/130.4.1016S_bib15","doi-asserted-by":"crossref","first-page":"7538","DOI":"10.1016\/S0021-9258(18)53209-9","article-title":"Identification of a low affinity, high capacity transporter of cationic amino acids in mouse liver","volume":"268","author":"Closs","year":"1993","journal-title":"J. Biol. Chem"},{"key":"10.1093\/jn\/130.4.1016S_bib16","doi-asserted-by":"crossref","first-page":"20796","DOI":"10.1016\/S0021-9258(19)36854-1","article-title":"Characterization of a third member of the MCAT family of cationic amino acid transporters","volume":"268","author":"Closs","year":"1993","journal-title":"J. Biol. Chem"},{"key":"10.1093\/jn\/130.4.1016S_bib17","doi-asserted-by":"crossref","first-page":"2565","DOI":"10.1046\/j.1471-4159.1998.71062565.x","article-title":"Glutamine uptake at the blood-brain barrier is mediated by N-system transport","volume":"71","author":"Ennis","year":"1998","journal-title":"J. Neurochem"},{"key":"10.1093\/jn\/130.4.1016S_bib18","doi-asserted-by":"crossref","first-page":"316","DOI":"10.1002\/ana.410330316","article-title":"Assessment of reliability and biological significance of glutamate levels in cerebrospinal fluid","volume":"33","author":"Ferrarese","year":"1993","journal-title":"Ann. Neurol"},{"key":"10.1093\/jn\/130.4.1016S_bib19","unstructured":"Filer, L. J., Garattini, S., Kare, M. R., Reynolds, M. A. & Wurtman, R. J. (1979) Assessment of reliability and biological significance of glutamate levels in cerebrospinal fluid. Glutamic Acid: Advances in Biochemistry and PhysiologyRaven PressNew York, NY."},{"key":"10.1093\/jn\/130.4.1016S_bib20","doi-asserted-by":"crossref","first-page":"2007","DOI":"10.1111\/j.1471-4159.1991.tb03460.x","article-title":"Blood-brain barrier transport of kynurenines: implications for brain synthesis and metabolism","volume":"56","author":"Fukui","year":"1991","journal-title":"J. Neurochem"},{"key":"10.1093\/jn\/130.4.1016S_bib21","doi-asserted-by":"crossref","first-page":"1010","DOI":"10.1139\/y91-152","article-title":"Morphology and physiology of capillary systems in subregions of the subfornical organ and area postrema","volume":"69","author":"Gross","year":"1991","journal-title":"Can. J. Physiol. Pharmacol"},{"key":"10.1093\/jn\/130.4.1016S_bib22","doi-asserted-by":"crossref","first-page":"73","DOI":"10.1016\/0361-9230(87)90035-9","article-title":"The microcirculation of rat circumventricular organs and pituitary glands","volume":"18","author":"Gross","year":"1987","journal-title":"Brain Res. Bull"},{"key":"10.1093\/jn\/130.4.1016S_bib23","doi-asserted-by":"crossref","first-page":"663","DOI":"10.1038\/jcbfm.1987.120","article-title":"Peering through the windows of the brain","volume":"7","author":"Gross","year":"1987","journal-title":"J. Cereb. Blood Flow Metab"},{"key":"10.1093\/jn\/130.4.1016S_bib24","doi-asserted-by":"crossref","unstructured":"Guidotti, G. G. & Gazzola, G. C. (1992) Amino acid transporters: systematic approach and principles of control. Kilberg, M.S.Haussinger, D. eds. Mammalian Amino Acid Transport:3\u201330Plenum PressNew York, NY.","DOI":"10.1007\/978-1-4899-1161-2_1"},{"key":"10.1093\/jn\/130.4.1016S_bib25","doi-asserted-by":"crossref","first-page":"19392","DOI":"10.1016\/S0021-9258(19)77645-5","article-title":"Neutral amino acid transport at the human blood-brain barrier","volume":"263","author":"Hargreaves","year":"1988","journal-title":"J. Biol. Chem"},{"key":"10.1093\/jn\/130.4.1016S_bib26","doi-asserted-by":"crossref","first-page":"207","DOI":"10.1007\/BF00583389","article-title":"Regional brain glutamate transport in rats at normal and raised concentrations of circulating glutamate","volume":"281","author":"Hawkins","year":"1995","journal-title":"Cell Tissue Res"},{"key":"10.1093\/jn\/130.4.1016S_bib27","doi-asserted-by":"crossref","first-page":"260","DOI":"10.1016\/0014-4886(85)90216-X","article-title":"High affinity transport of glutamate in rat brain microvessels","volume":"87","author":"Hutchinson","year":"1985","journal-title":"Exp. Neurol"},{"key":"10.1093\/jn\/130.4.1016S_bib28","first-page":"91","article-title":"Two distinct gene products mediate y+ type cationic amino acid transport in Xenopus oocytes and show different tissue expression patterns","volume":"1","author":"Kakuda","year":"1993","journal-title":"Transgene"},{"key":"10.1093\/jn\/130.4.1016S_bib29","doi-asserted-by":"crossref","first-page":"565","DOI":"10.1016\/S0955-0674(97)80035-X","article-title":"Family of neutral and acidic amino acid transporters: molecular biology, physiology and medical implications","volume":"9","author":"Kanai","year":"1997","journal-title":"Curr. Opin. Cell Biol"},{"key":"10.1093\/jn\/130.4.1016S_bib30","doi-asserted-by":"crossref","first-page":"23629","DOI":"10.1074\/jbc.273.37.23629","article-title":"Expression cloning and characterization of a transporter for large neutral amino acids activated by the heavy chain of 4F2 antigen","volume":"273","author":"Kanai","year":"1998","journal-title":"J. Biol. Chem"},{"key":"10.1093\/jn\/130.4.1016S_bib31","first-page":"1450","article-title":"A new family of neurotransmitter transporters: the high affinity glutamate transporters","volume":"8","author":"Kanai","year":"1994","journal-title":"FASEB J"},{"key":"10.1093\/jn\/130.4.1016S_bib32","doi-asserted-by":"crossref","first-page":"725","DOI":"10.1038\/352725a0","article-title":"Transport of cationic amino acids by the mouse ecotropic retrovirus receptor","volume":"35","author":"Kim","year":"1991","journal-title":"Nature (Lond.)"},{"key":"10.1093\/jn\/130.4.1016S_bib33","doi-asserted-by":"crossref","unstructured":"Landas, S., Fischer, J., Wilkin, L. D., Mitchell, L. D., Johnson, L. K., Turner, J. W., Theriac, M. & Moore, K. C. (1985) Demonstration of regional blood-brain barrier permeability in human brain. Neuroscience Letters 57(3):251\u2013256.","DOI":"10.1016\/0304-3940(85)90500-2"},{"key":"10.1093\/jn\/130.4.1016S_bib34","doi-asserted-by":"crossref","first-page":"C1101","DOI":"10.1152\/ajpcell.1998.274.4.C1101","article-title":"Glutamine transport by the blood-brain barrier: a possible mechanism for nitrogen removal","volume":"274","author":"Lee","year":"1998","journal-title":"Am. J. Physiol"},{"key":"10.1093\/jn\/130.4.1016S_bib35","doi-asserted-by":"crossref","first-page":"41","DOI":"10.1016\/0165-0173(90)90011-C","article-title":"Physiological and pathophysiological roles of excitatory animo acids during central nervous system development","volume":"15","author":"McDonald","year":"1990","journal-title":"Brain Res"},{"key":"10.1093\/jn\/130.4.1016S_bib36","doi-asserted-by":"crossref","first-page":"288","DOI":"10.1038\/26246","article-title":"Amino acid transport by heterodimers of 4F2hc\/CD98 and members of a permease family","volume":"395","author":"Mastroberardino","year":"1998","journal-title":"Nature"},{"key":"10.1093\/jn\/130.4.1016S_bib37","doi-asserted-by":"crossref","first-page":"293","DOI":"10.1016\/0165-0173(93)90014-Q","article-title":"Amino acids as dietary excitotoxins: a contribution to understanding neurodegenerative disorders","volume":"18","author":"Meldrum","year":"1993","journal-title":"Brain Res"},{"key":"10.1093\/jn\/130.4.1016S_bib38","doi-asserted-by":"crossref","first-page":"1291","DOI":"10.1111\/j.1471-4159.1987.tb05660.x","article-title":"Phenylalanine transport across the blood-brain barrier as studied with the in situ brain perfusion technique","volume":"48","author":"Momma","year":"1987","journal-title":"J. Neurochem"},{"key":"10.1093\/jn\/130.4.1016S_bib39","doi-asserted-by":"crossref","first-page":"597","DOI":"10.1126\/science.1329206","article-title":"Molecular diversity of glutamate receptors and implications for brain function","volume":"258","author":"Nakanishi","year":"1992","journal-title":"Science (Washington DC)"},{"key":"10.1093\/jn\/130.4.1016S_bib40","doi-asserted-by":"crossref","first-page":"1629","DOI":"10.1152\/ajplegacy.1971.221.6.1629","article-title":"Brain uptake of radiolabeled amino acids, amines, and hexoses after arterial injection","volume":"221","author":"Oldendorf","year":"1971","journal-title":"Am. J. Physiol"},{"key":"10.1093\/jn\/130.4.1016S_bib41","doi-asserted-by":"crossref","first-page":"94","DOI":"10.1152\/ajplegacy.1976.230.1.94","article-title":"Amino acid assignment to one of three blood-brain barrier amino acid carriers","volume":"230","author":"Oldendorf","year":"1976","journal-title":"Am. J. Physiol"},{"key":"10.1093\/jn\/130.4.1016S_bib42","doi-asserted-by":"crossref","first-page":"3686","DOI":"10.1016\/S0021-9258(19)75327-7","article-title":"Distinct mediating systems for the transport of neutral amino acids by the Ehrlich cell","volume":"238","author":"Oxender","year":"1963","journal-title":"J. Biol. Chem"},{"key":"10.1093\/jn\/130.4.1016S_bib43","doi-asserted-by":"crossref","first-page":"123","DOI":"10.1242\/jeb.196.1.123","article-title":"A new family of proteins (rBAT and 4F2hc) involved in cationic and zwitterionic amino acid transport: a tale of two proteins in search of a transport function","volume":"196","author":"Palac\u00edn","year":"1994","journal-title":"J. Exp. Biol"},{"key":"10.1093\/jn\/130.4.1016S_bib44","unstructured":"Pardridge, W. M. (1979) Regulation of amino acid availability to brain: selective control mechanisms for glutamate. Filer, L.J., Jr eds. Glutamic Acid: Advances in Biochemistry and Physiology:125\u2013137Raven PressNew York, NY."},{"key":"10.1093\/jn\/130.4.1016S_bib45","doi-asserted-by":"crossref","first-page":"1481","DOI":"10.1152\/physrev.1983.63.4.1481","article-title":"Brain metabolism: a perspective from the blood-brain barrier","volume":"63","author":"Pardridge","year":"1983","journal-title":"Physiol. Rev"},{"key":"10.1093\/jn\/130.4.1016S_bib46","doi-asserted-by":"crossref","unstructured":"Pardridge, W. M. (1998) Brain metabolism: a perspective from the blood-brain barrier. Introduction to the Blood-Brain BarrierCambridge University PressCambridge, UK.","DOI":"10.1017\/CBO9780511570216"},{"key":"10.1093\/jn\/130.4.1016S_bib47","doi-asserted-by":"crossref","first-page":"914","DOI":"10.1101\/gad.11.7.914","article-title":"Anemia and perinatal death result from loss of the murine ecotropic retrovirus receptor mCAT-1","volume":"11","author":"Perkins","year":"1997","journal-title":"Genes Dev"},{"key":"10.1093\/jn\/130.4.1016S_bib48","doi-asserted-by":"crossref","first-page":"39","DOI":"10.1017\/S0317167100031279","article-title":"Transfer constants for blood-brain barrier permeation of the neuroexcitatory shellfish toxin, domoic acid","volume":"18","author":"Preston","year":"1991","journal-title":"Can. J. Neurol. Sci"},{"key":"10.1093\/jn\/130.4.1016S_bib49","doi-asserted-by":"crossref","first-page":"351","DOI":"10.1016\/0006-8993(92)90731-N","article-title":"The uptake of anionic and cationic amino acids by the isolated perfused sheep choroid plexus","volume":"581","author":"Preston","year":"1992","journal-title":"Brain Res"},{"key":"10.1093\/jn\/130.4.1016S_bib50","doi-asserted-by":"crossref","first-page":"1774","DOI":"10.1111\/j.1471-4159.1981.tb00430.x","article-title":"Uptake of exogenous glutamate and aspartate by circumventricular organs but not other regions of brain","volume":"36","author":"Price","year":"1981","journal-title":"J. Neurochem"},{"key":"10.1093\/jn\/130.4.1016S_bib51","doi-asserted-by":"crossref","first-page":"740","DOI":"10.1111\/j.1471-4159.1984.tb02745.x","article-title":"Uptake of exogenous asparate into circumventricular organs but not other regions of adult mouse brain","volume":"42","author":"Price","year":"1984","journal-title":"J. Neurochem"},{"key":"10.1093\/jn\/130.4.1016S_bib52","doi-asserted-by":"crossref","first-page":"38","DOI":"10.3181\/00379727-209-43875","article-title":"Cloning of the rat ecotropic retroviral receptor and studies of its expression in intestinal tissues","volume":"209","author":"Puppi","year":"1995","journal-title":"Proc. Soc. Exp. Biol. Med"},{"key":"10.1093\/jn\/130.4.1016S_bib53","unstructured":"Refetoff, S. (1989) Thyroid function tests and effects of drugs on thyroid function. DeGroot, L.J. eds. Endocrinology2nd ed.:590\u2013639W. B. Saunders Philadelphia, PA."},{"key":"10.1093\/jn\/130.4.1016S_bib54","doi-asserted-by":"crossref","first-page":"25951","DOI":"10.1016\/S0021-9258(18)35701-6","article-title":"Neutral amino acid transport by the blood-brain barrier","volume":"267","author":"S\u00e1nchez del Pino","year":"1992","journal-title":"J. Biol. Chem"},{"key":"10.1093\/jn\/130.4.1016S_bib55","doi-asserted-by":"crossref","first-page":"14913","DOI":"10.1074\/jbc.270.25.14913","article-title":"Neutral amino acid transport characterization of isolated luminal and abluminal membranes of the blood-brain barrier","volume":"270","author":"S\u00e1nchez del Pino","year":"1995","journal-title":"J. Biol. Chem"},{"key":"10.1093\/jn\/130.4.1016S_bib56","first-page":"F1288","article-title":"Kinetics and Na independence of amino acid uptake by the blood side of the perfused sheep choroid plexus","volume":"258","author":"Segal","year":"1990","journal-title":"Am. J. Physiol"},{"key":"10.1093\/jn\/130.4.1016S_bib57","doi-asserted-by":"crossref","first-page":"437","DOI":"10.1007\/BF00319366","article-title":"Morphology and function of the capillary networks in subregions of the rat tuber cinereum","volume":"267","author":"Shaver","year":"1992","journal-title":"Cell Tissue Res"},{"key":"10.1093\/jn\/130.4.1016S_bib58","doi-asserted-by":"crossref","first-page":"1252","DOI":"10.1046\/j.1471-4159.1995.64031252.x","article-title":"Inhibition of neutral amino acid transport across the human blood-brain barrier by phenylalanine","volume":"64","author":"Shulkin","year":"1995","journal-title":"J. Neurochem"},{"key":"10.1093\/jn\/130.4.1016S_bib59","unstructured":"Smith, Q. R. (1990) Regulation of metal uptake and distribution in brain. Wurtman, R.J.Wurtman, J.J. eds. Nutrition and the BrainVol. 8:25\u201374Raven PressNew York, NY."},{"key":"10.1093\/jn\/130.4.1016S_bib60","doi-asserted-by":"crossref","first-page":"1651","DOI":"10.1111\/j.1471-4159.1987.tb01039.x","article-title":"Kinetics of neutral amino acid transport across the blood-brain barrier","volume":"49","author":"Smith","year":"1987","journal-title":"J. Neurochem"},{"key":"10.1093\/jn\/130.4.1016S_bib61","doi-asserted-by":"crossref","first-page":"1330","DOI":"10.1111\/j.1471-4159.1992.tb11346.x","article-title":"Facilitated transport of the neurotoxin \u03b2-N-methylaamino-L-alanine across the blood-brain barrier","volume":"58","author":"Smith","year":"1992","journal-title":"J. Neurochem"},{"key":"10.1093\/jn\/130.4.1016S_bib62","doi-asserted-by":"crossref","unstructured":"Smith, Q. R. & Stoll, J. (1998) Blood-brain barrier amino acid trasnport. Pardridge, W. M. eds. Introduction to the Blood-Brain Barrier:188\u2013197Cambridge University PressCambridge, UK.","DOI":"10.1017\/CBO9780511570216.020"},{"key":"10.1093\/jn\/130.4.1016S_bib63","doi-asserted-by":"crossref","unstructured":"Smith, Q. R. & Stoll, J. (1999) Blood-brain barrier amino acid trasnport. Molecular characterization of amino acid transporters at the blood-brain barrier 45:303\u2013317 Brain Barrier Systems Alfred Benzon Symposium.","DOI":"10.1017\/CBO9780511570216.020"},{"key":"10.1093\/jn\/130.4.1016S_bib64","doi-asserted-by":"crossref","first-page":"1956","DOI":"10.1111\/j.1471-4159.1993.tb13428.x","article-title":"Identification of the cationic amino acid transporter (System y+) of the rat blood-brain barrier","volume":"60","author":"Stoll","year":"1993","journal-title":"J. Neurochem"},{"key":"10.1093\/jn\/130.4.1016S_bib65","doi-asserted-by":"crossref","first-page":"1783","DOI":"10.1016\/0006-2952(95)02046-2","article-title":"Na+ and Cl-dependent transport of taurine at the blood-brain barrier","volume":"50","author":"Tamai","year":"1995","journal-title":"Biochem. Pharmacol"},{"key":"10.1093\/jn\/130.4.1016S_bib66","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1073\/pnas.89.1.1","article-title":"Expression cloning of a Na+-independent neutral amino acid transporter from rat kidney","volume":"89","author":"Tate","year":"1992","journal-title":"Proc. Natl. Acad. Sci. U.S.A"},{"key":"10.1093\/jn\/130.4.1016S_bib67","doi-asserted-by":"crossref","first-page":"168","DOI":"10.1016\/0005-2736(89)90362-3","article-title":"Sodium-dependent high affinity uptake of taurine by isolated rat brain capillaries","volume":"985","author":"Tayarani","year":"1989","journal-title":"Biochim. Biophys. Acta"},{"key":"10.1093\/jn\/130.4.1016S_bib68","doi-asserted-by":"crossref","first-page":"585","DOI":"10.1038\/jcbfm.1987.109","article-title":"Evidence for an alanine, serine, and cysteine system of transport in isolated brain capillaries","volume":"7","author":"Tayarani","year":"1987","journal-title":"J. Cereb. Blood Flow Metab"},{"key":"10.1093\/jn\/130.4.1016S_bib69","doi-asserted-by":"crossref","first-page":"729","DOI":"10.1038\/352729a0","article-title":"Cell-surface receptor for ecotropic murine retroviruses is a basic amino acid transporter","volume":"352","author":"Wang","year":"1991","journal-title":"Nature (Lond.)"},{"key":"10.1093\/jn\/130.4.1016S_bib70","doi-asserted-by":"crossref","first-page":"229","DOI":"10.1046\/j.1471-4159.1995.64010229.x","article-title":"Intracerebral dialysis and the blood-brain barrier","volume":"64","author":"Westergren","year":"1995","journal-title":"J. Neurochem"},{"key":"10.1093\/jn\/130.4.1016S_bib71","doi-asserted-by":"crossref","first-page":"4377","DOI":"10.1128\/jvi.66.7.4377-4381.1992","article-title":"Enhanced gene expression of the murine ecotropic retroviral receptor and its human homolog in proliferating cells","volume":"66","author":"Yoshimoto","year":"1992","journal-title":"J. Virol"}],"container-title":["The Journal of Nutrition"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0022316622140307?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0022316622140307?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/academic.oup.com\/jn\/article-pdf\/130\/4\/1016S\/24003267\/4w04t0s1016.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,4,30]],"date-time":"2024-04-30T22:15:57Z","timestamp":1714515357000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0022316622140307"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2000,4]]},"references-count":71,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2000,4]]}},"alternative-id":["S0022316622140307"],"URL":"https:\/\/doi.org\/10.1093\/jn\/130.4.1016s","relation":{},"ISSN":["0022-3166"],"issn-type":[{"value":"0022-3166","type":"print"}],"subject":[],"published":{"date-parts":[[2000,4]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Transport of Glutamate and Other Amino Acids at the Blood-Brain Barrier","name":"articletitle","label":"Article Title"},{"value":"The Journal of Nutrition","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1093\/jn\/130.4.1016S","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2000 American Society for Nutrition. Published by Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}]}}