{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,27]],"date-time":"2026-06-27T00:31:09Z","timestamp":1782520269239,"version":"3.54.5"},"reference-count":71,"publisher":"Elsevier BV","issue":"3","license":[{"start":{"date-parts":[[2001,3,1]],"date-time":"2001-03-01T00:00:00Z","timestamp":983404800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2023,2,11]],"date-time":"2023-02-11T00:00:00Z","timestamp":1676073600000},"content-version":"vor","delay-in-days":8017,"URL":"http:\/\/www.elsevier.com\/open-access\/userlicense\/1.0\/"}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["The Journal of Nutrition"],"published-print":{"date-parts":[[2001,3]]},"DOI":"10.1093\/jn\/131.3.1041s","type":"journal-article","created":{"date-parts":[[2018,1,19]],"date-time":"2018-01-19T13:55:11Z","timestamp":1516370111000},"page":"1041S-1045S","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":146,"title":["Mechanisms of Inhibition of Chemical Toxicity and Carcinogenesis by Diallyl Sulfide (DAS) and Related Compounds from Garlic"],"prefix":"10.1016","volume":"131","author":[{"given":"Chung S.","family":"Yang","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Saranjit K.","family":"Chhabra","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jun-Yan","family":"Hong","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Theresa J.","family":"Smith","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1093\/jn\/131.3.1041S_bib1","doi-asserted-by":"crossref","first-page":"445","DOI":"10.1093\/ajcn\/65.2.445","article-title":"Effect of garlic and fish-oil supplementation on serum lipid and lipoprotein concentrations in hypercholesterolemic men","volume":"65","author":"Adler","year":"1997","journal-title":"Am. J. Clin. Nutr"},{"key":"10.1093\/jn\/131.3.1041S_bib2","doi-asserted-by":"crossref","first-page":"97","DOI":"10.1016\/0741-8329(94)00089-1","article-title":"Alcohol-related cancer risk: a toxicokinetic hypothesis","volume":"12","author":"Anderson","year":"1995","journal-title":"Alcohol"},{"key":"10.1093\/jn\/131.3.1041S_bib3","doi-asserted-by":"crossref","first-page":"1063","DOI":"10.1093\/carcin\/4.8.1063","article-title":"Onion and garlic oils inhibit tumor promotion","volume":"4","author":"Belman","year":"1983","journal-title":"Carcinogenesis"},{"key":"10.1093\/jn\/131.3.1041S_bib4","unstructured":"Bertram, B. (1989) The modifying effect of disulfiram on the carcinogenicity of some N-nitrosamines: mechanistic investigations. In: Combination Effects in Chemical Carcinogenesis (Schmahl, D., ed.), pp. 195\u2013229. Velag Chemie, Weinheim, Germany."},{"key":"10.1093\/jn\/131.3.1041S_bib5","doi-asserted-by":"crossref","first-page":"114","DOI":"10.1038\/scientificamerican0385-114","article-title":"The chemistry of garlic and onions","volume":"252","author":"Block","year":"1985","journal-title":"Sci. Am"},{"key":"10.1093\/jn\/131.3.1041S_bib6","doi-asserted-by":"crossref","first-page":"642","DOI":"10.1021\/tx00024a008","article-title":"Inhibition of cytochrome P-450 2E1 by diallyl sulfide and its metabolites","volume":"4","author":"Brady","year":"1991","journal-title":"Chem. Res. Toxicol"},{"key":"10.1093\/jn\/131.3.1041S_bib7","first-page":"5937","article-title":"Effect of diallyl sulfide on rat liver microsomal nitrosamine metabolism and other monooxygenase activities","volume":"48","author":"Brady","year":"1988","journal-title":"Cancer Res"},{"key":"10.1093\/jn\/131.3.1041S_bib8","doi-asserted-by":"crossref","first-page":"342","DOI":"10.1016\/0041-008X(91)90123-V","article-title":"Modulation of rat hepatic microsomal monooxygenase enzymes and cytotoxicity by diallyl sulfide","volume":"108","author":"Brady","year":"1991","journal-title":"Toxicol. Appl. Pharmacol"},{"key":"10.1093\/jn\/131.3.1041S_bib9","doi-asserted-by":"crossref","first-page":"611","DOI":"10.1002\/ijc.2910440409","article-title":"A case-control study of gastric cancer and diet in Italy","volume":"44","author":"Buiatti","year":"1989","journal-title":"Int. J. Cancer"},{"key":"10.1093\/jn\/131.3.1041S_bib10","doi-asserted-by":"crossref","first-page":"273","DOI":"10.1111\/j.1574-695X.1996.tb00251.x","article-title":"Inhibition of Helicobacter pylori by garlic extract (Allium sativum)","volume":"13","author":"Cellini","year":"1996","journal-title":"FEMS Immunol. Med. Microbiol"},{"key":"10.1093\/jn\/131.3.1041S_bib11","doi-asserted-by":"crossref","first-page":"931","DOI":"10.1093\/jn\/110.5.931","article-title":"Effect of garlic on carbohydrate metabolism and lipid synthesis in rats","volume":"110","author":"Chang","year":"1980","journal-title":"J. Nutr"},{"key":"10.1093\/jn\/131.3.1041S_bib12","doi-asserted-by":"crossref","first-page":"761","DOI":"10.1016\/S0278-6915(98)00046-5","article-title":"Effects of the garlic components diallyl sulfide and diallyl disulfide on arylamine N-acetyltransferase activity in human colon tumor cells","volume":"36","author":"Chen","year":"1998","journal-title":"Food Chem. Toxicol"},{"key":"10.1093\/jn\/131.3.1041S_bib13","doi-asserted-by":"crossref","first-page":"127","DOI":"10.1002\/(SICI)1099-0461(1999)13:3\/4<127::AID-JBT2>3.0.CO;2-X","article-title":"Decrease of hepatic catalase level by treatment with diallyl sulfide and garlic homogenates in rats and mice","volume":"13","author":"Chen","year":"1999","journal-title":"J. Biochem. Mol. Toxicol"},{"key":"10.1093\/jn\/131.3.1041S_bib14","doi-asserted-by":"crossref","first-page":"2199","DOI":"10.1016\/0006-2952(94)00435-8","article-title":"Relationship between cytochrome P450 2E1 and acetone catabolism in rats as studied with diallyl sulfide as an inhibitor","volume":"48","author":"Chen","year":"1994","journal-title":"Biochem. Pharmacol"},{"key":"10.1093\/jn\/131.3.1041S_bib15","doi-asserted-by":"crossref","first-page":"2099","DOI":"10.1016\/0006-2952(95)02117-5","article-title":"The chemopreventive agent diallyl sulfide. A structurally atypical phenobarbital-type inducer","volume":"50","author":"Dragnev","year":"1995","journal-title":"Biochem. Pharmacol"},{"key":"10.1093\/jn\/131.3.1041S_bib16","doi-asserted-by":"crossref","first-page":"613","DOI":"10.1097\/00006454-199307000-00013","article-title":"Antibacterial activity of garlic and onions: a historical perspective","volume":"12","author":"Farbman","year":"1993","journal-title":"Pediatr. Infect. Dis. J"},{"key":"10.1093\/jn\/131.3.1041S_bib17","doi-asserted-by":"crossref","first-page":"1763","DOI":"10.1128\/AAC.32.12.1763","article-title":"In vitro mechanism of inhibition of bacterial cell growth by allicin","volume":"32","author":"Feldberg","year":"1988","journal-title":"Antimicrob. Agents Chemother"},{"issue":"suppl","key":"10.1093\/jn\/131.3.1041S_bib18","doi-asserted-by":"crossref","first-page":"100","DOI":"10.1002\/(SICI)1097-4644(1997)27+<100::AID-JCB16>3.0.CO;2-R","article-title":"Cancer prevention by organosulfur compounds from garlic and onion","volume":"27","author":"Fukushima","year":"1997","journal-title":"J. Cell Biochem"},{"key":"10.1093\/jn\/131.3.1041S_bib19","doi-asserted-by":"crossref","first-page":"61","DOI":"10.1080\/01635589609514428","article-title":"Inhibition of aflatoxin B1- and N-nitrosodiethylamine-induced liver preneoplastic foci in rats fed naturally occurring allyl sulfides","volume":"25","author":"Haber-Mignard","year":"1996","journal-title":"Nutr. Cancer"},{"key":"10.1093\/jn\/131.3.1041S_bib20","doi-asserted-by":"crossref","first-page":"407","DOI":"10.1093\/carcin\/14.3.407","article-title":"Effect of diallyl sulfide on aristolochic acid-induced forestomach carcinogenesis in rats","volume":"14","author":"Hadjiolov","year":"1993","journal-title":"Carcinogenesis"},{"key":"10.1093\/jn\/131.3.1041S_bib21","doi-asserted-by":"crossref","first-page":"1155","DOI":"10.1093\/carcin\/8.8.1155","article-title":"Inhibition of hepatocarcinogenic responses to 1,2-dimethylhydrazine by diallyl sulfide, a component of garlic oil","volume":"8","author":"Hayes","year":"1987","journal-title":"Carcinogenesis"},{"key":"10.1093\/jn\/131.3.1041S_bib22","doi-asserted-by":"crossref","first-page":"875","DOI":"10.1093\/carcin\/9.6.875","article-title":"Tobacco-specific nitrosamines, an important group of carcinogens in tobacco and tobacco smoke","volume":"9","author":"Hecht","year":"1988","journal-title":"Carcinogenesis"},{"key":"10.1093\/jn\/131.3.1041S_bib23","doi-asserted-by":"crossref","unstructured":"Hong, J. Y., Lin, M. C., Wang, Z. Y., Wang, E. J. & Yang, C. S. (1994) Inhibition of chemical toxicity and carcinogenesis by diallyl sulfide and diallyl sulfone. In: Food Phytochemicals for Cancer Prevention (Huang, M. T., Osawa, T., Ho, C. T. & Rosen, R.T., eds.), pp. 97\u2013101. ACS Symposium Series 546, Washington, DC.","DOI":"10.1021\/bk-1994-0546.ch006"},{"key":"10.1093\/jn\/131.3.1041S_bib24","first-page":"1509","article-title":"Metabolism of carcinogenic nitrosamines by rat nasal mucosa and the effect of diallyl sulfide","volume":"51","author":"Hong","year":"1991","journal-title":"Cancer Res"},{"key":"10.1093\/jn\/131.3.1041S_bib25","doi-asserted-by":"crossref","first-page":"901","DOI":"10.1093\/carcin\/13.5.901","article-title":"Inhibitory effects of diallyl sulfide on the metabolism and tumorigenicity of the tobacco-specific carcinogen 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK) in A\/J mouse lung","volume":"13","author":"Hong","year":"1992","journal-title":"Carcinogenesis"},{"key":"10.1093\/jn\/131.3.1041S_bib26","doi-asserted-by":"crossref","first-page":"963","DOI":"10.1016\/S0278-6915(96)00057-9","article-title":"Protective effects of diallyl sulfide on acetaminophen-induced toxicities","volume":"34","author":"Hu","year":"1996","journal-title":"Food Chem. Toxicol"},{"key":"10.1093\/jn\/131.3.1041S_bib27","doi-asserted-by":"crossref","first-page":"199","DOI":"10.1006\/abbi.1996.0550","article-title":"Glutathione S-transferases of female A\/J mouse liver and forestomach and their differential induction by anti-carcinogenic organosulfides from garlic","volume":"336","author":"Hu","year":"1996","journal-title":"Arch. Biochem. Biophys"},{"key":"10.1093\/jn\/131.3.1041S_bib28","doi-asserted-by":"crossref","first-page":"279","DOI":"10.1006\/abbi.1997.9915","article-title":"Glutathione S-transferases of female A\/J mouse lung and their induction by anticarcinogenic organosulfides from garlic","volume":"340","author":"Hu","year":"1997","journal-title":"Arch. Biochem. Biophys"},{"key":"10.1093\/jn\/131.3.1041S_bib29","doi-asserted-by":"crossref","first-page":"175","DOI":"10.1016\/0304-3835(90)90155-Q","article-title":"Chemopreventive action of garlic on methylcholanthrene-induced carcinogensis in the uterine cervix of mice","volume":"49","author":"Hussain","year":"1990","journal-title":"Cancer Lett"},{"key":"10.1093\/jn\/131.3.1041S_bib30","doi-asserted-by":"crossref","first-page":"908","DOI":"10.1111\/j.2042-7158.1997.tb06134.x","article-title":"Garlic compounds protect vascular endothelial cells from oxidized low density lipoprotein-induced injury","volume":"49","author":"Ide","year":"1997","journal-title":"J. Pharm. Pharmacol"},{"key":"10.1093\/jn\/131.3.1041S_bib31","doi-asserted-by":"crossref","first-page":"684","DOI":"10.1093\/ajcn\/28.7.684","article-title":"Garlic in alloxan-induced diabetic rabbits","volume":"28","author":"Jain","year":"1975","journal-title":"Am. J. Clin. Nutr"},{"key":"10.1093\/jn\/131.3.1041S_bib32","doi-asserted-by":"crossref","first-page":"318","DOI":"10.1021\/tx9601768","article-title":"Metabolism of the chemoprotective agent diallyl sulfide to glutathione conjugates in rats","volume":"10","author":"Jin","year":"1997","journal-title":"Chem. Res. Toxicol"},{"key":"10.1093\/jn\/131.3.1041S_bib33","doi-asserted-by":"crossref","first-page":"937","DOI":"10.1016\/S0271-5317(05)80057-0","article-title":"Allium sativum (garlic) and cancer prevention","volume":"10","author":"Lau","year":"1990","journal-title":"Nutr. Res"},{"key":"10.1093\/jn\/131.3.1041S_bib34","doi-asserted-by":"crossref","first-page":"131","DOI":"10.1016\/S0304-3835(97)04642-9","article-title":"In vivo antigenotoxic effects of dietary allyl sulfides in the rat","volume":"114","author":"LeBon","year":"1997","journal-title":"Cancer Lett"},{"key":"10.1093\/jn\/131.3.1041S_bib35","doi-asserted-by":"crossref","first-page":"11","DOI":"10.1002\/(SICI)1522-7146(1996)11:1<11::AID-JBT2>3.0.CO;2-Y","article-title":"Protective effect of diallyl sulfone against acetaminophen-induced hepatotoxicity in mice","volume":"11","author":"Lin","year":"1996","journal-title":"J. Biochem. Toxicol"},{"key":"10.1093\/jn\/131.3.1041S_bib36","doi-asserted-by":"crossref","first-page":"2467","DOI":"10.1093\/carcin\/13.12.2467","article-title":"Modulation of N-nitrosomethylbenzylamine bioactivation by diallyl sulfide in vivo","volume":"13","author":"Ludeke","year":"1992","journal-title":"Carcinogenesis"},{"key":"10.1093\/jn\/131.3.1041S_bib37","first-page":"337","article-title":"Hypolipidemic effect of garlic protein substituted for casein in diet of rats compared to those of garlic oil","volume":"34","author":"Mathew","year":"1996","journal-title":"Indian J. Exp. Biol"},{"key":"10.1093\/jn\/131.3.1041S_bib38","doi-asserted-by":"crossref","first-page":"121","DOI":"10.1016\/0304-3835(91)90205-V","article-title":"Differential induction of glutathione transferase isoenzymes of mice stomach by diallyl sulfide, a naturally occurring anticarcinogen","volume":"57","author":"Maurya","year":"1991","journal-title":"Cancer Lett"},{"key":"10.1093\/jn\/131.3.1041S_bib39","doi-asserted-by":"crossref","first-page":"S82","DOI":"10.1111\/j.1753-4887.1996.tb03823.x","article-title":"Garlic: its anticarcinogenic and antitumorigenic properties","volume":"54","author":"Milner","year":"1996","journal-title":"Nutr. Rev"},{"key":"10.1093\/jn\/131.3.1041S_bib40","doi-asserted-by":"crossref","first-page":"399","DOI":"10.1016\/S0021-9150(98)00293-7","article-title":"Daily supplementation with aged garlic extract, but not raw garlic, protects low-density lipoprotein against in vitro oxidation","volume":"143","author":"Munday","year":"1999","journal-title":"Atherosclerosis"},{"key":"10.1093\/jn\/131.3.1041S_bib41","doi-asserted-by":"crossref","first-page":"207","DOI":"10.1016\/0304-3835(92)90249-U","article-title":"Anticarcinogenic action of diallyl sulfide in hamster buccal pouch and forestomach","volume":"66","author":"Nagabhushan","year":"1992","journal-title":"Cancer Lett"},{"key":"10.1093\/jn\/131.3.1041S_bib42","doi-asserted-by":"crossref","first-page":"1055","DOI":"10.1007\/s11745-997-0136-7","article-title":"In vitro effect of garlic powder extract on lipid content in normal and atherosclerotic human aortic cells","volume":"32","author":"Orekhov","year":"1997","journal-title":"Lipids"},{"key":"10.1093\/jn\/131.3.1041S_bib43","doi-asserted-by":"crossref","first-page":"2323","DOI":"10.1016\/0006-2952(93)90206-C","article-title":"Regulation of cytochrome P450 2B1\/2 genes by diallyl sulfone, disulfiram, and other organosulfur compounds in primary cultures of rat hepatocytes","volume":"45","author":"Pan","year":"1993","journal-title":"Biochem. Pharmacol"},{"key":"10.1093\/jn\/131.3.1041S_bib44","doi-asserted-by":"crossref","first-page":"337","DOI":"10.1006\/abbi.1993.1220","article-title":"Transcriptional activation of cytochrome P450 2B1\/2 genes in rat liver by diallyl sulfide, a compound derived from garlic","volume":"302","author":"Pan","year":"1993","journal-title":"Arch. Biochem. Biophys"},{"key":"10.1093\/jn\/131.3.1041S_bib45","doi-asserted-by":"crossref","first-page":"511","DOI":"10.1021\/tx00034a019","article-title":"Cytochrome P450 enzymes involved in acetaminophen activation by rat and human liver microsomes and their kinetics","volume":"6","author":"Patten","year":"1993","journal-title":"Chem. Res. Toxicol"},{"key":"10.1093\/jn\/131.3.1041S_bib46","first-page":"1953","article-title":"Chemoprevention of diethylnitrosamine-induced liver foci and hepatocellular adenomas in C3H mice","volume":"15","author":"Pereira","year":"1995","journal-title":"Anticancer Res"},{"key":"10.1093\/jn\/131.3.1041S_bib47","doi-asserted-by":"crossref","first-page":"193","DOI":"10.1016\/0304-3835(88)90010-9","article-title":"Inhibitory action of garlic oil on the initiation of benzo[a]pyrene-induced skin carcinogenesis in mice","volume":"40","author":"Sadhna","year":"1988","journal-title":"Cancer Lett"},{"key":"10.1093\/jn\/131.3.1041S_bib48","doi-asserted-by":"crossref","first-page":"356","DOI":"10.1055\/s-2006-958099","article-title":"Anti-diabetic effects of onion and garlic sulfoxide amino acids in rats","volume":"61","author":"Sheela","year":"1995","journal-title":"Planta Med"},{"key":"10.1093\/jn\/131.3.1041S_bib49","doi-asserted-by":"crossref","first-page":"971","DOI":"10.1016\/S0278-6915(96)00066-X","article-title":"Effect of the active principle of garlic\u2014diallyl sulfide\u2014on cell viability, detoxification capability and the antioxidation system of primary rat hepatocytes","volume":"34","author":"Sheen","year":"1996","journal-title":"Food Chem. Toxicol"},{"key":"10.1093\/jn\/131.3.1041S_bib50","doi-asserted-by":"crossref","first-page":"209","DOI":"10.1016\/S0304-3835(98)00152-9","article-title":"Antitumor activity of diallyl sulfide on polycyclic aromatic hydrocarbon-induced mouse skin carcinogenesis","volume":"131","author":"Singh","year":"1998","journal-title":"Cancer Lett"},{"key":"10.1093\/jn\/131.3.1041S_bib51","first-page":"258","article-title":"Antitumor activity of diallyl sulfide in two-stage mouse skin model of carcinogenesis","volume":"11","author":"Singh","year":"1998","journal-title":"Biomed. Environ. Sci"},{"key":"10.1093\/jn\/131.3.1041S_bib52","doi-asserted-by":"crossref","first-page":"917","DOI":"10.1006\/bbrc.1998.8352","article-title":"Differential induction of NAD(P)H:quinone oxidoreductase by anti-carcinogenic organosulfides from garlic","volume":"244","author":"Singh","year":"1998","journal-title":"Biochem. Biophys. Res. Commun"},{"key":"10.1093\/jn\/131.3.1041S_bib53","doi-asserted-by":"crossref","first-page":"131","DOI":"10.1093\/carcin\/9.1.131","article-title":"Effects of organosulfur compounds from garlic and onions on benzo[a]pyrene-induced neoplasia and glutathione S-transferase activity in the mouse","volume":"9","author":"Sparnins","year":"1988","journal-title":"Carcinogenesis"},{"key":"10.1093\/jn\/131.3.1041S_bib54","doi-asserted-by":"crossref","first-page":"61","DOI":"10.1016\/S0304-3835(97)00237-1","article-title":"Mechanism of differential efficacy of garlic organosulfides in preventing benzo(a)pyrene-induced cancer in mice","volume":"118","author":"Srivastava","year":"1997","journal-title":"Cancer Lett"},{"key":"10.1093\/jn\/131.3.1041S_bib55","first-page":"5084","article-title":"Chemoprevention of 1,2-dimethylhydrazine-induced colon cancer in mice by naturally occurring organosulfur compounds","volume":"50","author":"Sumiyoshi","year":"1990","journal-title":"Cancer Res"},{"key":"10.1093\/jn\/131.3.1041S_bib56","doi-asserted-by":"crossref","first-page":"2467","DOI":"10.1093\/carcin\/16.10.2467","article-title":"Chemoprotective effects of capsaicin and diallyl sulfide against mutagenesis or tumorigenesis by vinyl carbamate and N-nitrosodimethylamine","volume":"16","author":"Surh","year":"1995","journal-title":"Carcinogenesis"},{"key":"10.1093\/jn\/131.3.1041S_bib57","first-page":"2037","article-title":"Binding of aflatoxin B1 to DNA inhibited by ajoene and diallyl sulfide","volume":"11","author":"Tadi","year":"1991","journal-title":"Anticancer Res"},{"key":"10.1093\/jn\/131.3.1041S_bib58","doi-asserted-by":"crossref","first-page":"87","DOI":"10.1080\/01635589109514116","article-title":"Organosulfur compounds of garlic modulate mutagenesis, metabolism, and DNA binding of aflatoxin B1","volume":"15","author":"Tadi","year":"1991","journal-title":"Nutr. Cancer"},{"key":"10.1093\/jn\/131.3.1041S_bib59","doi-asserted-by":"crossref","first-page":"235","DOI":"10.1093\/mutage\/11.3.235","article-title":"Naturally occurring diallyl disulfide inhibits the formation of carcinogenic heterocyclic aromatic amines in boiled pork juice","volume":"11","author":"Tsai","year":"1996","journal-title":"Mutagenesis"},{"key":"10.1093\/jn\/131.3.1041S_bib60","doi-asserted-by":"crossref","first-page":"1214","DOI":"10.1111\/j.1349-7006.1994.tb02932.x","article-title":"Chemopreventive effects of beta-carotene, alpha-tocopherol and five naturally occurring antioxidants on initiation of hepatocarcinogenesis by 2-amino-3-methylimidazo[4,5-f]quinoline in the rat","volume":"85","author":"Tsuda","year":"1994","journal-title":"Jpn. J. Cancer Res"},{"key":"10.1093\/jn\/131.3.1041S_bib61","doi-asserted-by":"crossref","first-page":"146","DOI":"10.1006\/taap.1996.0018","article-title":"Protective effects of garlic and related organosulfur compounds on acetaminophen-induced hepatotoxicity in mice","volume":"136","author":"Wang","year":"1996","journal-title":"Toxicol. Appl. Pharmacol"},{"key":"10.1093\/jn\/131.3.1041S_bib62","doi-asserted-by":"crossref","first-page":"487","DOI":"10.1093\/carcin\/8.3.487","article-title":"Diallyl sulfide, a flavor compound of garlic (Allium sativum), inhibits dimethylhydrazine-induced colon cancer","volume":"8","author":"Wargovich","year":"1987","journal-title":"Carcinogenesis"},{"key":"10.1093\/jn\/131.3.1041S_bib63","doi-asserted-by":"crossref","first-page":"39","DOI":"10.1016\/0304-3835(92)90019-R","article-title":"Initiation and post-initiation chemopreventive effects of diallyl sulfide in esophageal carcinogenesis","volume":"64","author":"Wargovich","year":"1992","journal-title":"Cancer Lett"},{"key":"10.1093\/jn\/131.3.1041S_bib64","doi-asserted-by":"crossref","first-page":"811","DOI":"10.1042\/bst0240811","article-title":"Allium vegetables: their role in the prevention of cancer","volume":"24","author":"Wargovich","year":"1996","journal-title":"Biochem. Soc. Trans"},{"key":"10.1093\/jn\/131.3.1041S_bib65","first-page":"6872","article-title":"Chemoprevention of N-nitrosomethylbenzylamine-induced esophageal cancer in rats by the naturally occurring thioether, diallyl sulfide","volume":"48","author":"Wargovich","year":"1988","journal-title":"Cancer Res"},{"key":"10.1093\/jn\/131.3.1041S_bib66","first-page":"2689","article-title":"Inhibition of N-nitrosodiethylamine carcinogenesis in mice by naturally occurring organosulfur compounds and monoterpenes","volume":"49","author":"Wattenberg","year":"1989","journal-title":"Cancer Res"},{"key":"10.1093\/jn\/131.3.1041S_bib67","doi-asserted-by":"crossref","unstructured":"Yang, C. S., Hong, J. Y. & Wang, Z. Y. (1993) Inhibition of nitrosamine-induced tumorigenesis by diallyl sulfide and tea. In: Food and Cancer Prevention: Chemical and Biological Aspects (Waldron, K. W., Johnson, I. T. & Fenwick, G. R., eds.), pp. 247\u2013252. Royal Society of Chemistry, UK.","DOI":"10.1533\/9781845698256.4.247"},{"key":"10.1093\/jn\/131.3.1041S_bib68","first-page":"1982S","article-title":"Cytochrome P-450 enzymes as targets for chemoprevention against chemical carcinogenesis and toxicity: opportunities and limitations","volume":"54","author":"Yang","year":"1994","journal-title":"Cancer Res"},{"key":"10.1093\/jn\/131.3.1041S_bib69","doi-asserted-by":"crossref","first-page":"113","DOI":"10.1007\/978-1-4899-0939-8_8","article-title":"Inhibition of tumorigenesis by chemicals from garlic and tea","volume":"354","author":"Yang","year":"1994","journal-title":"Adv. Exp. Med. Biol"},{"key":"10.1093\/jn\/131.3.1041S_bib70","doi-asserted-by":"crossref","first-page":"189","DOI":"10.1007\/BF02536728","article-title":"Garlic reduces plasma lipids by inhibiting hepatic cholesterol and triacylglycerol synthesis","volume":"29","author":"Yeh","year":"1994","journal-title":"Lipids"},{"key":"10.1093\/jn\/131.3.1041S_bib71","doi-asserted-by":"crossref","first-page":"162","DOI":"10.1093\/jnci\/81.2.162","article-title":"Allium vegetables and reduced risk of stomach cancer","volume":"81","author":"You","year":"1989","journal-title":"J. Natl. Cancer Inst"}],"container-title":["The Journal of Nutrition"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0022316622147930?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0022316622147930?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/academic.oup.com\/jn\/article-pdf\/131\/3\/1041S\/24003767\/4w03t1s1041.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,6,12]],"date-time":"2023-06-12T19:51:23Z","timestamp":1686599483000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0022316622147930"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2001,3]]},"references-count":71,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2001,3]]}},"alternative-id":["S0022316622147930"],"URL":"https:\/\/doi.org\/10.1093\/jn\/131.3.1041s","relation":{},"ISSN":["0022-3166"],"issn-type":[{"value":"0022-3166","type":"print"}],"subject":[],"published":{"date-parts":[[2001,3]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Mechanisms of Inhibition of Chemical Toxicity and Carcinogenesis by Diallyl Sulfide (DAS) and Related Compounds from Garlic","name":"articletitle","label":"Article Title"},{"value":"The Journal of Nutrition","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1093\/jn\/131.3.1041S","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2001 American Society for Nutrition. Published by Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}]}}