{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,12]],"date-time":"2026-10-12T16:23:43Z","timestamp":1791822223928,"version":"4.3.4"},"reference-count":37,"publisher":"Elsevier BV","issue":"10","license":[{"start":{"date-parts":[[2004,10,1]],"date-time":"2004-10-01T00:00:00Z","timestamp":1096588800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2023,2,6]],"date-time":"2023-02-06T00:00:00Z","timestamp":1675641600000},"content-version":"vor","delay-in-days":6702,"URL":"http:\/\/www.elsevier.com\/open-access\/userlicense\/1.0\/"}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["The Journal of Nutrition"],"published-print":{"date-parts":[[2004,10]]},"DOI":"10.1093\/jn\/134.10.2678","type":"journal-article","created":{"date-parts":[[2018,1,22]],"date-time":"2018-01-22T07:02:58Z","timestamp":1516604578000},"page":"2678-2684","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":191,"title":["Iron Fortification and Iron Supplementation are Cost-Effective Interventions to Reduce Iron Deficiency in Four Subregions of the World"],"prefix":"10.1016","volume":"134","author":[{"given":"Rob","family":"Baltussen","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"C\u00e9cile","family":"Knai","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mona","family":"Sharan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1093\/jn\/134.10.2678_bib1","unstructured":"ACC\/SCN (2000) Fourth report on the World Nutrition Situation. ACC\/SCN in Collaboration with IFPRI, Geneva, Switzerland."},{"key":"10.1093\/jn\/134.10.2678_bib2","unstructured":"Micronutrient deficiencies. Battling iron deficiency anemia. [Online] Nutrition Program, World Health Organization. http:\/\/www.who.int\/nut\/ida.htm [accessed April 30, 2003]."},{"key":"10.1093\/jn\/134.10.2678_bib3","unstructured":"World Health Organization (2001) Iron Deficiency Anemia. Assessment, Prevention and Control. A Guide for Program Managers. Geneva, Switzerland."},{"key":"10.1093\/jn\/134.10.2678_bib4","unstructured":"Nokes, C., van den Bosch, C. & Bundy, D.A.P. (1998) The Effects of Iron Deficiency and Anemia on Mental and Motor Performance, Educational Achievement, and Behavior in Children. An Annotated Bibliography. International Nutritional Anemia Consultative Group, U.S."},{"key":"10.1093\/jn\/134.10.2678_bib5","unstructured":"Stoltzfus, R., Mullany, L. & Black, R. E. (2003) Malnutrition and the global burden of disease: iron deficiency anemia and health outcomes. In: Comparative Quantification of Health Risks: The Global Burden of Disease Due to 25 Selected Major Risk Factors. Harvard University Press, Cambridge."},{"key":"10.1093\/jn\/134.10.2678_bib6","first-page":"106","article-title":"Health, nutrition and prosperity: a microeconomic perspective","volume":"80","author":"Thomas","year":"2002","journal-title":"Bull. World Health Organ"},{"key":"10.1093\/jn\/134.10.2678_bib7","unstructured":"UNICEF\/UNU\/WHO\/MI (1999) Preventing Iron Deficiency in Women and Children. Technical Consensus on Key Issues. Technical Workshop, UNICEF, New York, 7\u20139 October 1998. Boston: International Nutrition Foundation and Micronutrient Initiative."},{"key":"10.1093\/jn\/134.10.2678_bib8","doi-asserted-by":"crossref","first-page":"307","DOI":"10.1017\/S1368980001001562","article-title":"Toward public health nutrition strategies in the European Union to implement food based dietary guidelines and to enhance healthier lifestyles","volume":"4","author":"Stockley","year":"2001","journal-title":"Public Health Nutr"},{"key":"10.1093\/jn\/134.10.2678_bib9","doi-asserted-by":"crossref","first-page":"1606S","DOI":"10.1093\/jn\/133.5.1606S","article-title":"Nutritional interventions during pregnancy for the prevention or treatment of maternal morbidity and preterm delivery: an overview of randomized controlled trials","volume":"133","author":"Villar","year":"2003","journal-title":"J. Nutr"},{"key":"10.1093\/jn\/134.10.2678_bib10","unstructured":"Ross, J. & Horton, S. (1998) Economic Consequences of Iron Deficiency. Micronutrient Initiative, Ottawa, Canada."},{"key":"10.1093\/jn\/134.10.2678_bib11","unstructured":"Asian Development Bank (1999). Investing in child nutrition in Asia. Nutrition and Development Series, No. 1, Manila, Philippines."},{"issue":"Suppl.","key":"10.1093\/jn\/134.10.2678_bib12","first-page":"1","article-title":"Improving child nutrition in Asia","volume":"22","author":"Mason","year":"2001","journal-title":"Food Nutr. Bull"},{"issue":"Suppl.4","key":"10.1093\/jn\/134.10.2678_bib13","doi-asserted-by":"crossref","first-page":"794S","DOI":"10.1093\/jn\/132.4.794S","article-title":"Reversing productivity losses from iron deficiency: the economic case","volume":"132","author":"Hunt","year":"2002","journal-title":"J Nutr"},{"key":"10.1093\/jn\/134.10.2678_bib14","doi-asserted-by":"crossref","first-page":"51","DOI":"10.1016\/S0306-9192(02)00070-2","volume":"28","author":"Horton","year":"2003","journal-title":"The Economics of Iron Deficiency. Food Policy"},{"key":"10.1093\/jn\/134.10.2678_bib15","unstructured":"Asian Development Bank (1999). Improving child nutrition in Asia. Nutrition and Development Series, No. 3, Manila, Philippines."},{"key":"10.1093\/jn\/134.10.2678_bib16","doi-asserted-by":"crossref","unstructured":"Gold, M., Siegel, J., Russell, L. & Weinstein M. (1996) Cost-Effectiveness in Health and Medicine. Oxford University Press, New York, NY.","DOI":"10.1093\/oso\/9780195108248.001.0001"},{"key":"10.1093\/jn\/134.10.2678_bib17","unstructured":"Drummond, M., O\u2019Brien, B., Stoddart, G. & Torrance, G. (1997) Methods for the Economic Evaluation of Health Care Programs. 2nd ed. Oxford University Press, Oxford, UK."},{"key":"10.1093\/jn\/134.10.2678_bib18","unstructured":"Tan Torres, T., Baltussen, R. M., Adam T., Hutubessy, R. C., Acharya, A. & Evans, D. B. (2003) WHO Guide to Cost-Effectiveness Analysis. World Health Organization Geneva, Switzerland."},{"key":"10.1093\/jn\/134.10.2678_bib19","unstructured":"Murray, C.J.L. & Lopez, A. D. (1996) The Global Burden of Disease: A Comprehensive Assessment of Mortality and Disability from Diseases, Injuries, and Risk Factors in 1990 and Projected to 2020. Harvard University Press, Cambridge."},{"key":"10.1093\/jn\/134.10.2678_bib20","doi-asserted-by":"crossref","first-page":"235","DOI":"10.1002\/(SICI)1099-1050(200004)9:3<235::AID-HEC502>3.0.CO;2-O","article-title":"Development of WHO guidelines on generalized cost-effectiveness analysis","volume":"9","author":"Murray","year":"2000","journal-title":"Health Econ"},{"key":"10.1093\/jn\/134.10.2678_bib21","unstructured":"WHO-CHOICE: Choosing Interventions that are Cost-Effective [Online]. http:\/\/www.who.int\/evidence\/cea [accessed April 24, 2004]."},{"key":"10.1093\/jn\/134.10.2678_bib22","unstructured":"Stoltzfus, R. & Dreyfuss, M. (1998) Guidelines for the Use of Iron Supplements to Prevent and Treat Iron Deficiency Anemia. The International Nutritional Anemia Consultative Group (INACG\/WHO\/UNICEF), Washington, DC."},{"key":"10.1093\/jn\/134.10.2678_bib23","doi-asserted-by":"crossref","first-page":"381","DOI":"10.1016\/0277-9536(94)90135-X","article-title":"Determinants of compliance with iron supplementation: supplies, side effects, or psychology?","volume":"39","author":"Galloway","year":"1994","journal-title":"Soc. Sci. Med"},{"key":"10.1093\/jn\/134.10.2678_bib24","doi-asserted-by":"crossref","unstructured":"Hurrell, R., Bothwell, T., Cook, J. D., Dary, O., Davidsson, L., FairweatherTait, S., Hallberg, L., Lynch, S., Rosado, J., et al. (2002) SUSTAIN Task Force. The usefulness of elemental iron for cereal flour fortification: a SUSTAIN Task Force report. Sharing United States Technology to Aid in the Improvement of Nutrition. Nutr. Rev. 60: 391\u2013406.","DOI":"10.1301\/002966402320964061"},{"key":"10.1093\/jn\/134.10.2678_bib25","unstructured":"Allen, L. H. & Gillespie, S. R. (2001) What works. A review of the efficacy and effectiveness of nutrition interventions. Asian Development Bank, Manila, Philippines."},{"key":"10.1093\/jn\/134.10.2678_bib26","doi-asserted-by":"crossref","first-page":"274","DOI":"10.1093\/ajcn\/78.2.274","article-title":"Iron absorption from fish sauce and soy sauce fortified with sodium iron EDTA","volume":"78","author":"Fidler","year":"2003","journal-title":"Am. J. Clin. Nutr"},{"key":"10.1093\/jn\/134.10.2678_bib27","doi-asserted-by":"crossref","first-page":"284","DOI":"10.1093\/ajcn\/78.2.284","article-title":"Regular consumption of NaFeEDTA-fortified fish sauce improves iron status and reduces the prevalence of anemia in anemic Vietnamese women","volume":"78","author":"Thuy","year":"2003","journal-title":"Am. J. Clin. Nutr"},{"key":"10.1093\/jn\/134.10.2678_bib28","doi-asserted-by":"crossref","first-page":"425","DOI":"10.1093\/ajcn\/77.2.425","article-title":"Dual fortification of salt with iodine and microencapsulated iron: a randomized, double-blind, controlled trial in Moroccan schoolchildren","volume":"77","author":"Zimmermann","year":"2003","journal-title":"Am. J. Clin. Nutr"},{"key":"10.1093\/jn\/134.10.2678_bib29","doi-asserted-by":"crossref","first-page":"3","DOI":"10.1186\/1478-7547-1-3","article-title":"Econometric estimation of country-specific hospital costs","volume":"1","author":"Adam","year":"2002","journal-title":"Cost Eff. Resour. Alloc"},{"key":"10.1093\/jn\/134.10.2678_bib30","unstructured":"Online Pharmacy and Drugstore [Online]. http:\/\/www.drugstore.com[accessed April 24, 2004]."},{"key":"10.1093\/jn\/134.10.2678_bib31","unstructured":"International Drug Price Indicator Guide [Online]. http:\/\/www.erc.msh.org [accessed April 24, 2004]."},{"key":"10.1093\/jn\/134.10.2678_bib32","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1186\/1478-7547-1-1","article-title":"Program costs in the economic evaluation of health interventions","volume":"1","author":"Johns","year":"2003","journal-title":"Cost Eff. Resour. Alloc"},{"key":"10.1093\/jn\/134.10.2678_bib33","unstructured":"Nestel, P. & Nalubola, R. (2002) Manual for Wheat Flour Fortification with Iron. U.S. Agency for International Development, Arlington, VA."},{"key":"10.1093\/jn\/134.10.2678_bib34","unstructured":"WHO Commission on Macroeconomics and Health (2001) Macroeconomics and Health: Investing in Health for Economic Development. Report of the Commission on Macroeconomics and Health. World Health Organization, Geneva, Switzerland."},{"key":"10.1093\/jn\/134.10.2678_bib35","unstructured":"OMNI\/Roche\/USAID (1997) Fortification Basics: Choosing a Vehicle."},{"key":"10.1093\/jn\/134.10.2678_bib36","doi-asserted-by":"crossref","first-page":"288","DOI":"10.2105\/AJPH.92.2.288","article-title":"Effects of iron supplementation on maternal haematologic status in pregnancy","volume":"92","author":"Sloan","year":"2002","journal-title":"Am. J. Public Health"},{"key":"10.1093\/jn\/134.10.2678_bib37","doi-asserted-by":"crossref","first-page":"1392","DOI":"10.1093\/ajcn\/76.6.1392","article-title":"Efficacy and trial effectiveness of weekly and daily iron supplementation among pregnant women in rural Bangladesh: disentangling the issues","volume":"76","author":"Ekstrom","year":"2002","journal-title":"Am. J. Clin. Nutr"}],"container-title":["The Journal of Nutrition"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0022316623031061?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0022316623031061?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/academic.oup.com\/jn\/article-pdf\/134\/10\/2678\/24027501\/z4w01004002678.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,6,30]],"date-time":"2024-06-30T17:07:15Z","timestamp":1719767235000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0022316623031061"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2004,10]]},"references-count":37,"journal-issue":{"issue":"10","published-print":{"date-parts":[[2004,10]]}},"alternative-id":["S0022316623031061"],"URL":"https:\/\/doi.org\/10.1093\/jn\/134.10.2678","relation":{},"ISSN":["0022-3166"],"issn-type":[{"value":"0022-3166","type":"print"}],"subject":[],"published":{"date-parts":[[2004,10]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Iron Fortification and Iron Supplementation are Cost-Effective Interventions to Reduce Iron Deficiency in Four Subregions of the World","name":"articletitle","label":"Article Title"},{"value":"The Journal of Nutrition","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1093\/jn\/134.10.2678","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2004 American Society for Nutrition. Published by Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}]}}