{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,1]],"date-time":"2026-10-01T16:40:00Z","timestamp":1790872800595,"version":"4.1.0"},"reference-count":131,"publisher":"Elsevier BV","issue":"6","license":[{"start":{"date-parts":[[2006,6,1]],"date-time":"2006-06-01T00:00:00Z","timestamp":1149120000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2023,2,1]],"date-time":"2023-02-01T00:00:00Z","timestamp":1675209600000},"content-version":"vor","delay-in-days":6089,"URL":"http:\/\/www.elsevier.com\/open-access\/userlicense\/1.0\/"}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["The Journal of Nutrition"],"published-print":{"date-parts":[[2006,6]]},"DOI":"10.1093\/jn\/136.6.1731s","type":"journal-article","created":{"date-parts":[[2018,1,16]],"date-time":"2018-01-16T01:53:41Z","timestamp":1516067621000},"page":"1731S-1740S","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":389,"title":["The Hordaland Homocysteine Study: A Community-Based Study of Homocysteine, Its Determinants, and Associations with Disease"],"prefix":"10.1016","volume":"136","author":[{"given":"Helga","family":"Refsum","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eha","family":"Nurk","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"A.","family":"David Smith","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Per M.","family":"Ueland","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Clara G.","family":"Gjesdal","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ingvar","family":"Bjelland","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Aage","family":"Tverdal","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Grethe S.","family":"Tell","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ottar","family":"Nyg\u00e5rd","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Stein E.","family":"Vollset","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1093\/jn\/136.6.1731S_bib1","doi-asserted-by":"crossref","first-page":"S33","DOI":"10.1007\/s11745-001-0679-7","article-title":"The Hordaland Homocysteine Studies","volume":"36","author":"Ueland","year":"2001","journal-title":"Lipids"},{"key":"10.1093\/jn\/136.6.1731S_bib2","first-page":"1","article-title":"The cardiovascular disease study in Norwegian counties. Background and organization","volume":"634","author":"Bjartveit","year":"1979","journal-title":"Acta Med Scand Suppl"},{"key":"10.1093\/jn\/136.6.1731S_bib3","doi-asserted-by":"crossref","first-page":"75","DOI":"10.1093\/oxfordjournals.aje.a009921","article-title":"Evaluation of a food frequency questionnaire with weighed records, fatty acids, and alpha-tocopherol in adipose tissue and serum","volume":"150","author":"Andersen","year":"1999","journal-title":"Am J Epidemiol"},{"key":"10.1093\/jn\/136.6.1731S_bib4","first-page":"809","article-title":"Accuracy of a quantitative food frequency questionnaire applied in elderly Norwegian women","volume":"46","author":"Nes","year":"1992","journal-title":"Eur J Clin Nutr"},{"key":"10.1093\/jn\/136.6.1731S_bib5","doi-asserted-by":"crossref","first-page":"1526","DOI":"10.1001\/jama.1995.03530190040032","article-title":"Total plasma homocysteine and cardiovascular risk profile.The Hordaland Homocysteine Study","volume":"274","author":"Nyg\u00e5rd","year":"1995","journal-title":"JAMA"},{"key":"10.1093\/jn\/136.6.1731S_bib6","doi-asserted-by":"crossref","first-page":"618","DOI":"10.1001\/archpsyc.60.6.618","article-title":"Folate, vitamin B12, homocysteine, and the MTHFR 677C->T polymorphism in anxiety and depression: the Hordaland Homocysteine Study","volume":"60","author":"Bjelland","year":"2003","journal-title":"Arch Gen Psychiatry"},{"key":"10.1093\/jn\/136.6.1731S_bib7","doi-asserted-by":"crossref","first-page":"847","DOI":"10.1002\/ana.20645","article-title":"Plasma total homocysteine and cognition in the elderly. The Hordaland Homocysteine Study","volume":"58","author":"Nurk","year":"2005","journal-title":"Ann Neurol"},{"key":"10.1093\/jn\/136.6.1731S_bib8","doi-asserted-by":"crossref","first-page":"88","DOI":"10.1001\/archinte.166.1.88","article-title":"Plasma total homocysteine and bone mineral density. The Hordaland Homocysteine Study","volume":"166","author":"Gjesdal","year":"2006","journal-title":"Arch Intern Med"},{"key":"10.1093\/jn\/136.6.1731S_bib9","doi-asserted-by":"crossref","first-page":"709","DOI":"10.1080\/00365510410003057","article-title":"Distribution and determinants of serum creatinine in the general population: the Hordaland Health Study","volume":"64","author":"Vikse","year":"2004","journal-title":"Scand J Clin Lab Invest"},{"key":"10.1093\/jn\/136.6.1731S_bib10","series-title":"Homocysteine metabolism. From basic science to clinical medicine","first-page":"177","article-title":"he Hordaland homocysteine study: Lifestyle and and plasma homocysteine in Western Norway","author":"Vollset","year":"1997"},{"key":"10.1093\/jn\/136.6.1731S_bib11","doi-asserted-by":"crossref","first-page":"136","DOI":"10.1093\/ajcn\/65.1.136","article-title":"Coffee consumption and plasma total homocysteine: The Hordaland Homocysteine Study","volume":"65","author":"Nyg\u00e5rd","year":"1997","journal-title":"Am J Clin Nutr"},{"key":"10.1093\/jn\/136.6.1731S_bib12","doi-asserted-by":"crossref","first-page":"263","DOI":"10.1093\/ajcn\/67.2.263","article-title":"Major lifestyle determinants of plasma total homocysteine distribution: the Hordaland Homocysteine Study","volume":"67","author":"Nyg\u00e5rd","year":"1998","journal-title":"Am J Clin Nutr"},{"key":"10.1093\/jn\/136.6.1731S_bib13","doi-asserted-by":"crossref","first-page":"1244S","DOI":"10.1093\/jn\/126.suppl_4.1244S","article-title":"The Hordaland homocysteine study: the opposite tails odds ratios reveal differential effects of gender and intake of vitamin supplements at high and low plasma total homocysteine concentrations","volume":"126","author":"Refsum","year":"1996","journal-title":"J Nutr"},{"key":"10.1093\/jn\/136.6.1731S_bib14","doi-asserted-by":"crossref","first-page":"687","DOI":"10.1111\/j.1530-0277.1993.tb00820.x","article-title":"Elevated plasma homocysteine in alcoholics","volume":"17","author":"Hultberg","year":"1993","journal-title":"Alcohol Clin Exp Res"},{"key":"10.1093\/jn\/136.6.1731S_bib15","doi-asserted-by":"crossref","first-page":"215","DOI":"10.1055\/s-2005-872407","article-title":"Homocysteine-lowering trials for prevention of heart disease and stroke","volume":"5","author":"Clarke","year":"2005","journal-title":"Semin Vasc Med"},{"key":"10.1093\/jn\/136.6.1731S_bib16","doi-asserted-by":"crossref","first-page":"812","DOI":"10.1093\/ajcn\/79.5.812","article-title":"Changes in lifestyle and plasma total homocysteine: the Hordaland Homocysteine Study","volume":"79","author":"Nurk","year":"2004","journal-title":"Am J Clin Nutr"},{"key":"10.1093\/jn\/136.6.1731S_bib17","doi-asserted-by":"crossref","first-page":"2174","DOI":"10.1172\/JCI119024","article-title":"Determinants and vitamin responsiveness of intermediate hyperhomocysteinemia (\u226540 micromol\/liter). The Hordaland Homocysteine Study","volume":"98","author":"Guttormsen","year":"1996","journal-title":"J Clin Invest"},{"key":"10.1093\/jn\/136.6.1731S_bib18","doi-asserted-by":"crossref","first-page":"709","DOI":"10.1056\/NEJM198509193131201","article-title":"Heterozygosity for homocystinuria in premature peripheral and cerebral occlusive arterial disease","volume":"313","author":"Boers","year":"1985","journal-title":"N Engl J Med"},{"key":"10.1093\/jn\/136.6.1731S_bib19","doi-asserted-by":"crossref","first-page":"1764","DOI":"10.1093\/clinchem\/39.9.1764","article-title":"Total homocysteine in plasma or serum: methods and clinical applications","volume":"39","author":"Ueland","year":"1993","journal-title":"Clin Chem"},{"key":"10.1093\/jn\/136.6.1731S_bib20","doi-asserted-by":"crossref","first-page":"2693","DOI":"10.1001\/jama.1993.03510220049033","article-title":"Vitamin status and intake as primary determinants of homocysteinemia in an elderly population","volume":"270","author":"Selhub","year":"1993","journal-title":"JAMA"},{"key":"10.1093\/jn\/136.6.1731S_bib21","doi-asserted-by":"crossref","first-page":"482","DOI":"10.1093\/ajcn\/69.3.482","article-title":"Serum total homocysteine concentrations in adolescent and adult Americans: results from the third National Health and Nutrition Examination Survey","volume":"69","author":"Jacques","year":"1999","journal-title":"Am J Clin Nutr"},{"key":"10.1093\/jn\/136.6.1731S_bib22","doi-asserted-by":"crossref","first-page":"2643","DOI":"10.1093\/jn\/133.8.2643","article-title":"Serum total homocysteine concentrations in children and adolescents: results from the third National Health and Nutrition Examination Survey (NHANES III)","volume":"133","author":"Must","year":"2003","journal-title":"J Nutr"},{"key":"10.1093\/jn\/136.6.1731S_bib23","doi-asserted-by":"crossref","first-page":"3416","DOI":"10.1093\/jn\/133.11.3416","article-title":"Age and gender affect the relation between methylenetetrahydrofolate reductase C677T genotype and fasting plasma homocysteine concentrations in the Framingham Offspring Study Cohort","volume":"133","author":"Russo","year":"2003","journal-title":"J Nutr"},{"key":"10.1093\/jn\/136.6.1731S_bib24","doi-asserted-by":"crossref","first-page":"3","DOI":"10.1373\/clinchem.2003.021634","article-title":"Facts and recommendations about total homocysteine determinations: an expert opinion","volume":"50","author":"Refsum","year":"2004","journal-title":"Clin Chem"},{"key":"10.1093\/jn\/136.6.1731S_bib25","doi-asserted-by":"crossref","first-page":"480","DOI":"10.1038\/sj.ejcn.1602097","article-title":"Prevalences of hyperhomocysteinemia, unfavorable cholesterol profile and hypertension in European populations","volume":"59","author":"de Bree","year":"2005","journal-title":"Eur J Clin Nutr"},{"key":"10.1093\/jn\/136.6.1731S_bib26","doi-asserted-by":"crossref","first-page":"2473","DOI":"10.1161\/01.STR.29.12.2473","article-title":"Total homocyst(e)ine concentration and the likelihood of nonfatal stroke: results from the Third National Health and Nutrition Examination Survey, 1988\u20131994","volume":"29","author":"Giles","year":"1998","journal-title":"Stroke"},{"key":"10.1093\/jn\/136.6.1731S_bib27","doi-asserted-by":"crossref","first-page":"826","DOI":"10.1093\/ajcn\/77.4.826","article-title":"Demographic, health, lifestyle, and blood vitamin determinants of serum total homocysteine concentrations in the third National Health and Nutrition Examination Survey, 1988\u20131994","volume":"77","author":"Ganji","year":"2003","journal-title":"Am J Clin Nutr"},{"key":"10.1093\/jn\/136.6.1731S_bib28","doi-asserted-by":"crossref","first-page":"124","DOI":"10.1055\/s-2005-872398","article-title":"Effect of drugs on homocysteine concentrations","volume":"5","author":"Dierkes","year":"2005","journal-title":"Semin Vasc Med"},{"key":"10.1093\/jn\/136.6.1731S_bib29","doi-asserted-by":"crossref","first-page":"825","DOI":"10.1177\/0091270003255920","article-title":"Comparative effects of atorvastatin, simvastatin, and fenofibrate on serum homocysteine levels in patients with primary hyperlipidemia","volume":"43","author":"Milionis","year":"2003","journal-title":"J Clin Pharmacol"},{"key":"10.1093\/jn\/136.6.1731S_bib30","doi-asserted-by":"crossref","first-page":"172","DOI":"10.1055\/s-2005-872402","article-title":"Homocysteine and endothelial function in human studies","volume":"5","author":"Moat","year":"2005","journal-title":"Semin Vasc Med"},{"key":"10.1093\/jn\/136.6.1731S_bib31","doi-asserted-by":"crossref","first-page":"1408","DOI":"10.1515\/CCLM.2003.216","article-title":"Does homocysteine cause hypertension?","volume":"41","author":"Stehouwer","year":"2003","journal-title":"Clin Chem Lab Med"},{"key":"10.1093\/jn\/136.6.1731S_bib32","doi-asserted-by":"crossref","first-page":"1114","DOI":"10.1016\/0735-1097(90)90542-W","article-title":"Plasma homocyst(e)ine levels in men with premature coronary artery disease","volume":"16","author":"Genest","year":"1990","journal-title":"J Am Coll Cardiol"},{"key":"10.1093\/jn\/136.6.1731S_bib33","doi-asserted-by":"crossref","first-page":"128","DOI":"10.1016\/0741-5214(91)90020-U","article-title":"The association of elevated plasma homocyst(e)ine with progression of symptomatic peripheral arterial disease","volume":"13","author":"Taylor","year":"1991","journal-title":"J Vasc Surg"},{"key":"10.1093\/jn\/136.6.1731S_bib34","doi-asserted-by":"crossref","first-page":"232","DOI":"10.1161\/01.ATV.15.2.232","article-title":"Redox status and protein binding of plasma homocysteine and other aminothiols in patients with early-onset peripheral vascular disease. Homocysteine and peripheral vascular disease","volume":"15","author":"Mansoor","year":"1995","journal-title":"Arterioscler Thromb Vasc Biol"},{"key":"10.1093\/jn\/136.6.1731S_bib35","doi-asserted-by":"crossref","first-page":"150","DOI":"10.1093\/aje\/154.2.150","article-title":"Lifestyle factors and plasma homocysteine concentrations in a general population sample","volume":"154","author":"de Bree","year":"2001","journal-title":"Am J Epidemiol"},{"key":"10.1093\/jn\/136.6.1731S_bib36","doi-asserted-by":"crossref","first-page":"613","DOI":"10.1093\/ajcn\/73.3.613","article-title":"Determinants of plasma total homocysteine concentration in the Framingham Offspring cohort","volume":"73","author":"Jacques","year":"2001","journal-title":"Am J Clin Nutr"},{"key":"10.1093\/jn\/136.6.1731S_bib37","doi-asserted-by":"crossref","first-page":"1142","DOI":"10.1038\/sj.ejcn.1601942","article-title":"Effect of lifestyle factors on plasma total homocysteine concentrations in relation to MTHFR(C677T) genotype.Inter99 (7)","volume":"58","author":"Husemoen","year":"2004","journal-title":"Eur J Clin Nutr"},{"key":"10.1093\/jn\/136.6.1731S_bib38","doi-asserted-by":"crossref","first-page":"117","DOI":"10.1191\/1358863x04vm542oa","article-title":"The associations between smoking, physical activity, dietary habits and plasma homocysteine levels in cardiovascular disease-free people: the \u2018ATTICA\u2019 study","volume":"9","author":"Chrysohoou","year":"2004","journal-title":"Vasc Med"},{"key":"10.1093\/jn\/136.6.1731S_bib39","doi-asserted-by":"crossref","first-page":"279","DOI":"10.1080\/003655102760145834","article-title":"Does short-term smoking cessation reduce plasma total homocysteine concentrations?","volume":"62","author":"Tonstad","year":"2002","journal-title":"Scand J Clin Lab Invest"},{"key":"10.1093\/jn\/136.6.1731S_bib40","doi-asserted-by":"crossref","first-page":"23","DOI":"10.1002\/clc.4950250107","article-title":"Smoking cessation, but not smoking reduction, reduces plasma homocysteine levels","volume":"25","author":"Stein","year":"2002","journal-title":"Clin Cardiol"},{"key":"10.1093\/jn\/136.6.1731S_bib41","doi-asserted-by":"crossref","first-page":"1279","DOI":"10.1093\/ajcn\/76.6.1279","article-title":"Homocysteine, cardiovascular disease risk factors, and habitual diet in the French Supplementation with Antioxidant Vitamins and Minerals Study","volume":"76","author":"Mennen","year":"2002","journal-title":"Am J Clin Nutr"},{"key":"10.1093\/jn\/136.6.1731S_bib42","doi-asserted-by":"crossref","first-page":"1518","DOI":"10.1515\/CCLM.2003.233","article-title":"Homocysteine increases during endurance exercise","volume":"41","author":"Herrmann","year":"2003","journal-title":"Clin Chem Lab Med"},{"key":"10.1093\/jn\/136.6.1731S_bib43","doi-asserted-by":"crossref","first-page":"114","DOI":"10.1159\/000070032","article-title":"Influence of training volume and acute physical exercise on the homocysteine levels in endurance-trained men: interactions with plasma folate and vitamin B12","volume":"47","author":"Konig","year":"2003","journal-title":"Ann Nutr Metab"},{"key":"10.1093\/jn\/136.6.1731S_bib44","doi-asserted-by":"crossref","first-page":"467","DOI":"10.1093\/ajcn\/69.3.467","article-title":"Association of dietary protein intake and coffee consumption with serum homocysteine concentrations in an older population","volume":"69","author":"Stolzenberg-Solomon","year":"1999","journal-title":"Am J Clin Nutr"},{"key":"10.1093\/jn\/136.6.1731S_bib45","doi-asserted-by":"crossref","first-page":"480","DOI":"10.1093\/ajcn\/71.2.480","article-title":"Unfiltered coffee increases plasma homocysteine concentrations in healthy volunteers: a randomized trial","volume":"71","author":"Grubben","year":"2000","journal-title":"Am J Clin Nutr"},{"key":"10.1093\/jn\/136.6.1731S_bib46","doi-asserted-by":"crossref","first-page":"1107","DOI":"10.1093\/ajcn\/72.5.1107","article-title":"Heavy coffee consumption and plasma homocysteine: a randomized controlled trial in healthy volunteers","volume":"72","author":"Urgert","year":"2000","journal-title":"Am J Clin Nutr"},{"key":"10.1093\/jn\/136.6.1731S_bib47","doi-asserted-by":"crossref","first-page":"532","DOI":"10.1093\/ajcn\/73.3.532","article-title":"Consumption of high doses of chlorogenic acid, present in coffee, or of black tea increases plasma total homocysteine concentrations in humans","volume":"73","author":"Olthof","year":"2001","journal-title":"Am J Clin Nutr"},{"key":"10.1093\/jn\/136.6.1731S_bib48","doi-asserted-by":"crossref","first-page":"1244","DOI":"10.1093\/ajcn\/76.6.1244","article-title":"Contribution of caffeine to the homocysteine-raising effect of coffee: a randomized controlled trial in humans","volume":"76","author":"Verhoef","year":"2002","journal-title":"Am J Clin Nutr"},{"key":"10.1093\/jn\/136.6.1731S_bib49","doi-asserted-by":"crossref","first-page":"1253","DOI":"10.1038\/sj.ejcn.1601957","article-title":"Trigonelline is not responsible for the acute increase in plasma homocysteine following ingestion of instant coffee","volume":"58","author":"Slow","year":"2004","journal-title":"Eur J Clin Nutr"},{"key":"10.1093\/jn\/136.6.1731S_bib50","doi-asserted-by":"crossref","first-page":"155","DOI":"10.1093\/ajcn\/82.1.155","article-title":"Alcohol intake and methylenetetrahydrofolate reductase polymorphism modify the relation of folate intake to plasma homocysteine","volume":"82","author":"Chiuve","year":"2005","journal-title":"Am J Clin Nutr"},{"key":"10.1093\/jn\/136.6.1731S_bib51","doi-asserted-by":"crossref","first-page":"334","DOI":"10.1093\/ajcn\/78.2.334","article-title":"Relation between homocysteine concentrations and the consumption of different types of alcoholic beverages: the French Supplementation with Antioxidant Vitamins and Minerals Study","volume":"78","author":"Mennen","year":"2003","journal-title":"Am J Clin Nutr"},{"key":"10.1093\/jn\/136.6.1731S_bib52","doi-asserted-by":"crossref","first-page":"1522","DOI":"10.1016\/S0140-6736(00)02172-3","article-title":"Effect of consumption of red wine, spirits, and beer on serum homocysteine","volume":"355","author":"van der Gaag","year":"2000","journal-title":"Lancet"},{"key":"10.1093\/jn\/136.6.1731S_bib53","doi-asserted-by":"crossref","first-page":"201","DOI":"10.1055\/s-2005-872405","article-title":"Homocysteine and methionine metabolism in renal failure","volume":"5","author":"van Guldener","year":"2005","journal-title":"Semin Vasc Med"},{"key":"10.1093\/jn\/136.6.1731S_bib54","doi-asserted-by":"crossref","first-page":"98","DOI":"10.1055\/s-2005-872396","article-title":"Genetic determinants of plasma total homocysteine","volume":"5","author":"Gellekink","year":"2005","journal-title":"Semin Vasc Med"},{"key":"10.1093\/jn\/136.6.1731S_bib55","doi-asserted-by":"crossref","first-page":"1069","DOI":"10.1515\/CCLM.2005.187","article-title":"Betaine: a key modulator of one-carbon metabolism and homocysteine status","volume":"43","author":"Ueland","year":"2005","journal-title":"Clin Chem Lab Med"},{"key":"10.1093\/jn\/136.6.1731S_bib56","doi-asserted-by":"crossref","first-page":"110","DOI":"10.1055\/s-2005-872397","article-title":"Dietary determinants of plasma homocysteine concentrations","volume":"5","author":"Verhoef","year":"2005","journal-title":"Semin Vasc Med"},{"key":"10.1093\/jn\/136.6.1731S_bib57","first-page":"1","article-title":"The natural history of homocystinuria due to cystathionine beta-synthase deficiency","volume":"37","author":"Mudd","year":"1985","journal-title":"Am J Hum Genet"},{"key":"10.1093\/jn\/136.6.1731S_bib58","doi-asserted-by":"crossref","first-page":"738","DOI":"10.1023\/A:1005445132327","article-title":"Homocystinuria due to cystathionine beta-synthase deficiency in Ireland: 25 years' experience of a newborn screened and treated population with reference to clinical outcome and biochemical control","volume":"21","author":"Yap","year":"1998","journal-title":"J Inherit Metab Dis"},{"key":"10.1093\/jn\/136.6.1731S_bib59","doi-asserted-by":"crossref","first-page":"2080","DOI":"10.1161\/hq1201.100225","article-title":"Vascular outcome in patients with homocystinuria due to cystathionine beta-synthase deficiency treated chronically: a multicenter observational study","volume":"21","author":"Yap","year":"2001","journal-title":"Arterioscler Thromb Vasc Biol"},{"key":"10.1093\/jn\/136.6.1731S_bib60","doi-asserted-by":"crossref","first-page":"962","DOI":"10.1093\/ajcn\/71.4.962","article-title":"Plasma total homocysteine, pregnancy complications, and adverse pregnancy outcomes: the Hordaland Homocysteine study","volume":"71","author":"Vollset","year":"2000","journal-title":"Am J Clin Nutr"},{"key":"10.1093\/jn\/136.6.1731S_bib61","doi-asserted-by":"crossref","first-page":"26","DOI":"10.1016\/j.amjmed.2004.01.019","article-title":"Associations between maternal methylenetetrahydrofolate reductase polymorphisms and adverse outcomes of pregnancy: the Hordaland Homocysteine Study","volume":"117","author":"Nurk","year":"2004","journal-title":"Am J Med"},{"key":"10.1093\/jn\/136.6.1731S_bib62","doi-asserted-by":"crossref","first-page":"2719","DOI":"10.2174\/1381612043383692","article-title":"Consequences of elevated homocysteine during embryonic development and possible modes of action","volume":"10","author":"Brauer","year":"2004","journal-title":"Curr Pharm Des"},{"key":"10.1093\/jn\/136.6.1731S_bib63","doi-asserted-by":"crossref","first-page":"1293","DOI":"10.1373\/clinchem.2004.035709","article-title":"Homocysteine and folate in pregnancy","volume":"50","author":"Ueland","year":"2004","journal-title":"Clin Chem"},{"key":"10.1093\/jn\/136.6.1731S_bib64","doi-asserted-by":"crossref","first-page":"190","DOI":"10.1055\/s-2005-872404","article-title":"Homocysteine and folic acid: implications for pregnancy","volume":"5","author":"Daly","year":"2005","journal-title":"Semin Vasc Med"},{"key":"10.1093\/jn\/136.6.1731S_bib65","doi-asserted-by":"crossref","first-page":"411","DOI":"10.1097\/01.AOG.0000151117.52952.b6","article-title":"Mapping the theories of preeclampsia: the role of homocysteine","volume":"105","author":"Mignini","year":"2005","journal-title":"Obstet Gynecol"},{"key":"10.1093\/jn\/136.6.1731S_bib66","doi-asserted-by":"crossref","first-page":"1776","DOI":"10.1001\/archinte.162.15.1776","article-title":"Association between folic acid food fortification and hypertension or preeclampsia in pregnancy","volume":"162","author":"Ray","year":"2002","journal-title":"Arch Intern Med"},{"key":"10.1093\/jn\/136.6.1731S_bib67","doi-asserted-by":"crossref","first-page":"796","DOI":"10.1016\/S0140-6736(01)05969-4","article-title":"Folic acid supplements during pregnancy and risk of miscarriage","volume":"358","author":"Gindler","year":"2001","journal-title":"Lancet"},{"key":"10.1093\/jn\/136.6.1731S_bib68","doi-asserted-by":"crossref","first-page":"112","DOI":"10.1111\/j.1365-3016.2005.00633.x","article-title":"Folic acid supplements in pregnancy and birth outcome: re-analysis of a large randomised controlled trial and update of Cochrane review","volume":"19","author":"Charles","year":"2005","journal-title":"Paediatr Perinat Epidemiol"},{"key":"10.1093\/jn\/136.6.1731S_bib69","doi-asserted-by":"crossref","first-page":"806","DOI":"10.1093\/aje\/kwf129","article-title":"Risk of gestational hypertension in relation to folic acid supplementation during pregnancy","volume":"156","author":"Hernandez-Diaz","year":"2002","journal-title":"Am J Epidemiol"},{"key":"10.1093\/jn\/136.6.1731S_bib70","doi-asserted-by":"crossref","first-page":"1081","DOI":"10.1038\/sj.ejcn.1602215","article-title":"Effects of prenatal multimicronutrient supplements on birth weight and perinatal mortality: a randomised, controlled trial in Guinea-Bissau","volume":"59","author":"Kaestel","year":"2005","journal-title":"Eur J Clin Nutr"},{"key":"10.1093\/jn\/136.6.1731S_bib71","doi-asserted-by":"crossref","first-page":"1776","DOI":"10.1093\/jn\/135.7.1776","article-title":"Multivitamin supplementation of HIV-positive women during pregnancy reduces hypertension","volume":"135","author":"Merchant","year":"2005","journal-title":"J Nutr"},{"key":"10.1093\/jn\/136.6.1731S_bib72","doi-asserted-by":"crossref","first-page":"130","DOI":"10.1093\/ajcn\/74.1.130","article-title":"Plasma total homocysteine and cardiovascular and noncardiovascular mortality: the Hordaland Homocysteine Study","volume":"74","author":"Vollset","year":"2001","journal-title":"Am J Clin Nutr"},{"key":"10.1093\/jn\/136.6.1731S_bib73","doi-asserted-by":"crossref","first-page":"1374","DOI":"10.1001\/archinte.162.12.1374","article-title":"Plasma total homocysteine and hospitalizations for cardiovascular disease: the Hordaland Homocysteine Study","volume":"162","author":"Nurk","year":"2002","journal-title":"Arch Intern Med"},{"key":"10.1093\/jn\/136.6.1731S_bib74","doi-asserted-by":"crossref","first-page":"230","DOI":"10.1056\/NEJM199707243370403","article-title":"Plasma homocysteine levels and mortality in patients with coronary artery disease","volume":"337","author":"Nyg\u00e5rd","year":"1997","journal-title":"N Engl J Med"},{"key":"10.1093\/jn\/136.6.1731S_bib75","doi-asserted-by":"crossref","first-page":"1077","DOI":"10.1001\/archinte.159.10.1077","article-title":"Nonfasting plasma total homocysteine levels and all-cause and cardiovascular disease mortality in elderly Framingham men and women","volume":"159","author":"Bostom","year":"1999","journal-title":"Arch Intern Med"},{"key":"10.1093\/jn\/136.6.1731S_bib76","doi-asserted-by":"crossref","first-page":"321","DOI":"10.7326\/0003-4819-131-5-199909070-00002","article-title":"Nonfasting plasma total homocysteine level and mortality in middle-aged and elderly men and women in Jerusalem","volume":"131","author":"Kark","year":"1999","journal-title":"Ann Intern Med"},{"key":"10.1093\/jn\/136.6.1731S_bib77","doi-asserted-by":"crossref","first-page":"862","DOI":"10.1001\/archinte.158.8.862","article-title":"Homocysteine and ischemic heart disease: results of a prospective study with implications regarding prevention","volume":"158","author":"Wald","year":"1998","journal-title":"Arch Intern Med"},{"key":"10.1093\/jn\/136.6.1731S_bib78","doi-asserted-by":"crossref","first-page":"255","DOI":"10.1111\/j.1365-2796.2005.01450.x","article-title":"Homocysteine as a risk factor for CVD mortality in men with other CVD risk factors: the Kuopio Ischaemic Heart Disease Risk Factor (KIHD) Study","volume":"257","author":"Virtanen","year":"2005","journal-title":"J Intern Med"},{"key":"10.1093\/jn\/136.6.1731S_bib79","doi-asserted-by":"crossref","first-page":"601","DOI":"10.1161\/01.CIR.0000112581.96154.EA","article-title":"Serum homocysteine in relation to mortality and morbidity from coronary heart disease: a 24-year follow-up of the population study of women in Gothenburg","volume":"109","author":"Zylberstein","year":"2004","journal-title":"Circulation"},{"key":"10.1093\/jn\/136.6.1731S_bib80","doi-asserted-by":"crossref","first-page":"591","DOI":"10.1016\/S0002-9149(02)02561-4","article-title":"Relation of plasma total homocysteine to cardiovascular mortality in a French population","volume":"90","author":"Blacher","year":"2002","journal-title":"Am J Cardiol"},{"key":"10.1093\/jn\/136.6.1731S_bib81","doi-asserted-by":"crossref","first-page":"369","DOI":"10.1016\/S0021-9150(02)00373-8","article-title":"Coronary heart disease mortality, plasma homocysteine, and B-vitamins: a prospective study","volume":"166","author":"de Bree","year":"2003","journal-title":"Atherosclerosis"},{"key":"10.1093\/jn\/136.6.1731S_bib82","doi-asserted-by":"crossref","first-page":"2015","DOI":"10.1001\/jama.288.16.2015","article-title":"Homocysteine and risk of ischemic heart disease and stroke: a meta-analysis","volume":"288","year":"2002","journal-title":"JAMA"},{"key":"10.1093\/jn\/136.6.1731S_bib83","doi-asserted-by":"crossref","first-page":"292","DOI":"10.1111\/j.1538-7836.2005.01141.x","article-title":"Homocysteine, MTHFR and risk of venous thrombosis: a meta-analysis of published epidemiological studies","volume":"3","author":"Den Heijer","year":"2005","journal-title":"J Thromb Haemost"},{"key":"10.1093\/jn\/136.6.1731S_bib84","doi-asserted-by":"crossref","first-page":"1202","DOI":"10.1136\/bmj.325.7374.1202","article-title":"Homocysteine and cardiovascular disease: evidence on causality from a meta-analysis","volume":"325","author":"Wald","year":"2002","journal-title":"BMJ"},{"key":"10.1093\/jn\/136.6.1731S_bib85","doi-asserted-by":"crossref","first-page":"2023","DOI":"10.1001\/jama.288.16.2023","article-title":"MTHFR 677C\u2192T polymorphism and risk of coronary heart disease: a meta-analysis","volume":"288","author":"Klerk","year":"2002","journal-title":"JAMA"},{"key":"10.1093\/jn\/136.6.1731S_bib86","doi-asserted-by":"crossref","first-page":"445","DOI":"10.1093\/aje\/kwh228","article-title":"An integrated approach to the meta-analysis of genetic association studies using Mendelian randomization","volume":"160","author":"Minelli","year":"2004","journal-title":"Am J Epidemiol"},{"key":"10.1093\/jn\/136.6.1731S_bib87","doi-asserted-by":"crossref","first-page":"1053","DOI":"10.1136\/bmj.38611.658947.55","article-title":"Meta-analysis of MTHFR 677C->T polymorphism and coronary heart disease: does totality of evidence support causal role for homocysteine and preventive potential of folate?","volume":"331","author":"Lewis","year":"2005","journal-title":"BMJ"},{"key":"10.1093\/jn\/136.6.1731S_bib88","doi-asserted-by":"crossref","first-page":"973","DOI":"10.1001\/jama.288.8.973","article-title":"Effect of homocysteine-lowering therapy with folic acid, vitamin B12, and vitamin B6 on clinical outcome after percutaneous coronary intervention: the Swiss Heart study: a randomized controlled trial","volume":"288","author":"Schnyder","year":"2002","journal-title":"JAMA"},{"key":"10.1093\/jn\/136.6.1731S_bib89","doi-asserted-by":"crossref","first-page":"2673","DOI":"10.1056\/NEJMoa032845","article-title":"Folate therapy and in-stent restenosis after coronary stenting","volume":"350","author":"Lange","year":"2004","journal-title":"N Engl J Med"},{"key":"10.1093\/jn\/136.6.1731S_bib90","doi-asserted-by":"crossref","first-page":"565","DOI":"10.1001\/jama.291.5.565","article-title":"Lowering homocysteine in patients with ischemic stroke to prevent recurrent stroke, myocardial infarction, and death: the Vitamin Intervention for Stroke Prevention (VISP) randomized controlled trial","volume":"291","author":"Toole","year":"2004","journal-title":"JAMA"},{"key":"10.1093\/jn\/136.6.1731S_bib91","doi-asserted-by":"crossref","first-page":"1578","DOI":"10.1056\/NEJMoa055227","article-title":"Homocysteine lowering and cardiovascular events after acute myocardial infarction","volume":"354","author":"Bonaa","year":"2006","journal-title":"N Engl J Med"},{"key":"10.1093\/jn\/136.6.1731S_bib92","doi-asserted-by":"crossref","first-page":"2404","DOI":"10.1161\/01.STR.0000185929.38534.f3","article-title":"Vitamin Intervention For Stroke Prevention trial: an efficacy analysis","volume":"36","author":"Spence","year":"2005","journal-title":"Stroke"},{"key":"10.1093\/jn\/136.6.1731S_bib93","doi-asserted-by":"crossref","first-page":"1449","DOI":"10.1056\/NEJM199905133401901","article-title":"The effect of folic acid fortification on plasma folate and total homocysteine concentrations","volume":"340","author":"Jacques","year":"1999","journal-title":"N Engl J Med"},{"key":"10.1093\/jn\/136.6.1731S_bib94","doi-asserted-by":"crossref","first-page":"1335","DOI":"10.1161\/CIRCULATIONAHA.105.570846","article-title":"Improvement in stroke mortality in Canada and the United States, 1990 to 2002","volume":"113","author":"Yang","year":"2006","journal-title":"Circulation"},{"key":"10.1093\/jn\/136.6.1731S_bib95","doi-asserted-by":"crossref","first-page":"158","DOI":"10.1016\/j.amjmed.2003.10.024","article-title":"Effect of folic acid fortification of food on homocysteine-related mortality","volume":"116","author":"Anderson","year":"2004","journal-title":"Am J Med"},{"key":"10.1093\/jn\/136.6.1731S_bib96","doi-asserted-by":"crossref","first-page":"34","DOI":"10.1016\/j.ahj.2004.02.004","article-title":"Homocysteine and cardiovascular disease: biological mechanisms, observational epidemiology, and the need for randomized trials","volume":"148","author":"Splaver","year":"2004","journal-title":"Am Heart J"},{"key":"10.1093\/jn\/136.6.1731S_bib97","doi-asserted-by":"crossref","first-page":"163","DOI":"10.1055\/s-2005-872401","article-title":"Mechanisms of the atherogenic effects of elevated homocysteine in experimental models","volume":"5","author":"Wilson","year":"2005","journal-title":"Semin Vasc Med"},{"key":"10.1093\/jn\/136.6.1731S_bib98","doi-asserted-by":"crossref","first-page":"1076","DOI":"10.1515\/CCLM.2005.188","article-title":"Molecular targeting by homocysteine: a mechanism for vascular pathogenesis","volume":"43","author":"Jacobsen","year":"2005","journal-title":"Clin Chem Lab Med"},{"key":"10.1093\/jn\/136.6.1731S_bib99","doi-asserted-by":"crossref","first-page":"477","DOI":"10.1002\/hup.614","article-title":"Folic acid: neurochemistry, metabolism and relationship to depression","volume":"19","author":"Paul","year":"2004","journal-title":"Hum Psychopharmacol"},{"key":"10.1093\/jn\/136.6.1731S_bib100","doi-asserted-by":"crossref","first-page":"386","DOI":"10.1111\/j.1600-0447.1992.tb03285.x","article-title":"Plasma homocysteine in vascular disease and in nonvascular dementia of depressed elderly people","volume":"86","author":"Bell","year":"1992","journal-title":"Acta Psychiatr Scand"},{"key":"10.1093\/jn\/136.6.1731S_bib101","doi-asserted-by":"crossref","first-page":"426","DOI":"10.1176\/ajp.154.3.426","article-title":"Folate, vitamin B12, and homocysteine in major depressive disorder","volume":"154","author":"Fava","year":"1997","journal-title":"Am J Psychiatry"},{"key":"10.1093\/jn\/136.6.1731S_bib102","doi-asserted-by":"crossref","first-page":"715","DOI":"10.1176\/appi.ajp.157.5.715","article-title":"Vitamin B(12) deficiency and depression in physically disabled older women: epidemiologic evidence from the Women's Health and Aging Study","volume":"157","author":"Penninx","year":"2000","journal-title":"Am J Psychiatry"},{"key":"10.1093\/jn\/136.6.1731S_bib103","doi-asserted-by":"crossref","first-page":"529","DOI":"10.1017\/S0033291704003721","article-title":"Relationship of homocysteine, folic acid and vitamin B12 with depression in a middle-aged community sample","volume":"35","author":"Sachdev","year":"2005","journal-title":"Psychol Med"},{"key":"10.1093\/jn\/136.6.1731S_bib104","doi-asserted-by":"crossref","first-page":"2099","DOI":"10.1176\/appi.ajp.159.12.2099","article-title":"Vitamin B12, folate, and homocysteine in depression: the Rotterdam Study","volume":"159","author":"Tiemeier","year":"2002","journal-title":"Am J Psychiatry"},{"key":"10.1093\/jn\/136.6.1731S_bib105","doi-asserted-by":"crossref","first-page":"1574","DOI":"10.1093\/ajcn\/80.6.1574","article-title":"Association between depressive symptoms and serum concentrations of homocysteine in men: a population study","volume":"80","author":"Tolmunen","year":"2004","journal-title":"Am J Clin Nutr"},{"key":"10.1093\/jn\/136.6.1731S_bib106","doi-asserted-by":"crossref","first-page":"80","DOI":"10.1159\/000068692","article-title":"Depression and folate status in the US Population","volume":"72","author":"Morris","year":"2003","journal-title":"Psychother Psychosom"},{"key":"10.1093\/jn\/136.6.1731S_bib107","doi-asserted-by":"crossref","first-page":"1024","DOI":"10.1093\/ajcn\/80.4.1024","article-title":"Plasma folate concentrations are associated with depressive symptoms in elderly Latina women despite folic acid fortification","volume":"80","author":"Ramos","year":"2004","journal-title":"Am J Clin Nutr"},{"key":"10.1093\/jn\/136.6.1731S_bib108","doi-asserted-by":"crossref","first-page":"1103","DOI":"10.1016\/j.pnpbp.2005.06.021","article-title":"Homocysteine and folate metabolism in depression","volume":"29","author":"Bottiglieri","year":"2005","journal-title":"Prog Neuropsychopharmacol Biol Psychiatry"},{"key":"10.1093\/jn\/136.6.1731S_bib109","doi-asserted-by":"crossref","first-page":"785","DOI":"10.1093\/ajcn\/75.5.785","article-title":"Homocysteine, B vitamins, and cognitive deficit in the elderly","volume":"75","author":"Smith","year":"2002","journal-title":"Am J Clin Nutr"},{"key":"10.1093\/jn\/136.6.1731S_bib110","doi-asserted-by":"crossref","first-page":"425","DOI":"10.1016\/S1474-4422(03)00438-1","article-title":"Homocysteine and Alzheimer's disease","volume":"2","author":"Morris","year":"2003","journal-title":"Lancet Neurol"},{"key":"10.1093\/jn\/136.6.1731S_bib111","doi-asserted-by":"crossref","first-page":"209","DOI":"10.1055\/s-2005-872406","article-title":"Homocysteine and cognitive function","volume":"5","author":"Troen","year":"2005","journal-title":"Semin Vasc Med"},{"key":"10.1093\/jn\/136.6.1731S_bib112","doi-asserted-by":"crossref","first-page":"636","DOI":"10.1093\/ajcn\/82.3.636","article-title":"Homocysteine and folate as risk factors for dementia and Alzheimer disease","volume":"82","author":"Ravaglia","year":"2005","journal-title":"Am J Clin Nutr"},{"key":"10.1093\/jn\/136.6.1731S_bib113","doi-asserted-by":"crossref","first-page":"1449","DOI":"10.1001\/archneur.55.11.1449","article-title":"Folate, vitamin B12, and serum total homocysteine levels in confirmed Alzheimer disease","volume":"55","author":"Clarke","year":"1998","journal-title":"Arch Neurol"},{"key":"10.1093\/jn\/136.6.1731S_bib114","doi-asserted-by":"crossref","first-page":"440","DOI":"10.1093\/ageing\/31.6.440","article-title":"Minimal hippocampal width relates to plasma homocysteine in community-dwelling older people","volume":"31","author":"Williams","year":"2002","journal-title":"Age Ageing"},{"key":"10.1093\/jn\/136.6.1731S_bib115","doi-asserted-by":"crossref","first-page":"170","DOI":"10.1093\/brain\/awg006","article-title":"Homocysteine and brain atrophy on MRI of non-demented elderly","volume":"126","author":"den Heijer","year":"2003","journal-title":"Brain"},{"key":"10.1093\/jn\/136.6.1731S_bib116","doi-asserted-by":"crossref","first-page":"1752","DOI":"10.1523\/JNEUROSCI.22-05-01752.2002","article-title":"Folic acid deficiency and homocysteine impair DNA repair in hippocampal neurons and sensitize them to amyloid toxicity in experimental models of Alzheimer's disease","volume":"22","author":"Kruman","year":"2002","journal-title":"J Neurosci"},{"key":"10.1093\/jn\/136.6.1731S_bib117","doi-asserted-by":"crossref","first-page":"1073","DOI":"10.1016\/0026-0495(85)90082-4","article-title":"Folic acid responsive postmenopausal homocysteinemia","volume":"34","author":"Brattstrom","year":"1985","journal-title":"Metabolism"},{"key":"10.1093\/jn\/136.6.1731S_bib118","doi-asserted-by":"crossref","first-page":"190","DOI":"10.1007\/s002230010038","article-title":"Association of methylenetetrahydrofolate reductase (MTHFR) polymorphism with bone mineral density in postmenopausal Japanese women","volume":"66","author":"Miyao","year":"2000","journal-title":"Calcif Tissue Int"},{"key":"10.1093\/jn\/136.6.1731S_bib119","doi-asserted-by":"crossref","first-page":"2033","DOI":"10.1056\/NEJMoa032546","article-title":"Homocysteine levels and the risk of osteoporotic fracture","volume":"350","author":"van Meurs","year":"2004","journal-title":"N Engl J Med"},{"key":"10.1093\/jn\/136.6.1731S_bib120","doi-asserted-by":"crossref","first-page":"2042","DOI":"10.1056\/NEJMoa032739","article-title":"Homocysteine as a predictive factor for hip fracture in older persons","volume":"350","author":"McLean","year":"2004","journal-title":"N Engl J Med"},{"key":"10.1093\/jn\/136.6.1731S_bib121","doi-asserted-by":"crossref","first-page":"1894","DOI":"10.1007\/s00198-005-1961-x","article-title":"Association of red blood cell 5-methyltetrahydrofolate folate with bone mineral density in postmenopausal Iranian women","volume":"16","author":"Golbahar","year":"2005","journal-title":"Osteoporos Int"},{"key":"10.1093\/jn\/136.6.1731S_bib122","doi-asserted-by":"crossref","first-page":"234","DOI":"10.1016\/j.bone.2005.04.017","article-title":"Relation between homocysteine and B-vitamin status indicators and bone mineral density in older Americans","volume":"37","author":"Morris","year":"2005","journal-title":"Bone"},{"key":"10.1093\/jn\/136.6.1731S_bib123","doi-asserted-by":"crossref","first-page":"341","DOI":"10.1007\/s00394-004-0531-x","article-title":"Low bone mineral density and bone mineral content are associated with low cobalamin status in adolescents","volume":"44","author":"Dhonukshe-Rutten","year":"2005","journal-title":"Eur J Nutr"},{"key":"10.1093\/jn\/136.6.1731S_bib124","doi-asserted-by":"crossref","first-page":"1082","DOI":"10.1001\/jama.293.9.1082","article-title":"Effect of folate and mecobalamin on hip fractures in patients with stroke: a randomized controlled trial","volume":"293","author":"Sato","year":"2005","journal-title":"JAMA"},{"key":"10.1093\/jn\/136.6.1731S_bib125","doi-asserted-by":"crossref","first-page":"159","DOI":"10.1016\/0925-4439(95)00119-0","article-title":"Evidence for McKusick's hypothesis of deficient collagen cross-linking in patients with homocystinuria","volume":"1315","author":"Lubec","year":"1996","journal-title":"Biochim Biophys Acta"},{"key":"10.1093\/jn\/136.6.1731S_bib126","doi-asserted-by":"crossref","first-page":"921","DOI":"10.1359\/JBMR.050202","article-title":"Homocysteine and vitamin B12 status relate to bone turnover markers, broadband ultrasound attenuation, and fractures in healthy elderly people","volume":"20","author":"Dhonukshe-Rutten","year":"2005","journal-title":"J Bone Miner Res"},{"key":"10.1093\/jn\/136.6.1731S_bib127","doi-asserted-by":"crossref","first-page":"1118","DOI":"10.1515\/CCLM.2005.195","article-title":"Relation between homocysteine and biochemical bone turnover markers and bone mineral density in peri- and post-menopausal women","volume":"43","author":"Herrmann","year":"2005","journal-title":"Clin Chem Lab Med"},{"key":"10.1093\/jn\/136.6.1731S_bib128","doi-asserted-by":"crossref","first-page":"12","DOI":"10.1016\/j.bbadis.2005.03.004","article-title":"Homocysteine attenuates the expression of osteocalcin but enhances osteopontin in MC3T3\u2013E1 preosteoblastic cells","volume":"1740","author":"Sakamoto","year":"2005","journal-title":"Biochim Biophys Acta"},{"key":"10.1093\/jn\/136.6.1731S_bib129","doi-asserted-by":"crossref","first-page":"2348","DOI":"10.1373\/clinchem.2005.053363","article-title":"Increased osteoclast activity in the presence of increased homocysteine concentrations","volume":"51","author":"Herrmann","year":"2005","journal-title":"Clin Chem"},{"key":"10.1093\/jn\/136.6.1731S_bib130","doi-asserted-by":"crossref","first-page":"1190","DOI":"10.1093\/gerona\/60.9.1190","article-title":"The role of homocysteine in multisystem age-related problems: a systematic review","volume":"60","author":"Kuo","year":"2005","journal-title":"J Gerontol A Biol Sci Med Sci"},{"key":"10.1093\/jn\/136.6.1731S_bib131","first-page":"2855","article-title":"[Occurrence of musculoskeletal complaints in Hordaland](Nor)","volume":"123","author":"Sirnes","year":"2003","journal-title":"Tidsskr Nor Laegeforen"}],"container-title":["The Journal of Nutrition"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S002231662208316X?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S002231662208316X?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/academic.oup.com\/jn\/article-pdf\/136\/6\/1731S\/23897088\/1731s.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,6,12]],"date-time":"2023-06-12T11:02:49Z","timestamp":1686567769000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S002231662208316X"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2006,6]]},"references-count":131,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2006,6]]}},"alternative-id":["S002231662208316X"],"URL":"https:\/\/doi.org\/10.1093\/jn\/136.6.1731s","relation":{},"ISSN":["0022-3166"],"issn-type":[{"value":"0022-3166","type":"print"}],"subject":[],"published":{"date-parts":[[2006,6]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"The Hordaland Homocysteine Study: A Community-Based Study of Homocysteine, Its Determinants, and Associations with Disease","name":"articletitle","label":"Article Title"},{"value":"The Journal of Nutrition","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1093\/jn\/136.6.1731S","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2006 American Society of Nutrition. Published by Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}]}}