{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,29]],"date-time":"2026-09-29T11:10:38Z","timestamp":1790680238468,"version":"4.1.0"},"reference-count":52,"publisher":"Elsevier BV","issue":"11","license":[{"start":{"date-parts":[[2020,11,1]],"date-time":"2020-11-01T00:00:00Z","timestamp":1604188800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2023,1,17]],"date-time":"2023-01-17T00:00:00Z","timestamp":1673913600000},"content-version":"vor","delay-in-days":807,"URL":"http:\/\/www.elsevier.com\/open-access\/userlicense\/1.0\/"}],"funder":[{"name":"R\u00e9gion Nouvelle Aquitain"},{"DOI":"10.13039\/501100008530","name":"FEDER","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100008530","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["The Journal of Nutrition"],"published-print":{"date-parts":[[2020,11]]},"DOI":"10.1093\/jn\/nxaa244","type":"journal-article","created":{"date-parts":[[2020,8,4]],"date-time":"2020-08-04T19:25:41Z","timestamp":1596569141000},"page":"2900-2911","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":16,"title":["Rapeseed Lecithin Increases Lymphatic Lipid Output and \u03b1-Linolenic Acid Bioavailability in Rats"],"prefix":"10.1016","volume":"150","author":[{"given":"Chlo\u00e9","family":"Robert","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Leslie","family":"Cou\u00ebdelo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Carole","family":"Knibbe","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Laurence","family":"Fonseca","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Charline","family":"Buisson","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Elisabeth","family":"Errazuriz-Cerda","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Emmanuelle","family":"Meugnier","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Emmanuelle","family":"Loizon","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Carole","family":"Vaysse","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marie-Caroline","family":"Michalski","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1093\/jn\/nxaa244_bib1","doi-asserted-by":"crossref","first-page":"177","DOI":"10.1016\/j.foodpol.2013.12.001","article-title":"Sustainability labels on food products: consumer motivation, understanding and use.","volume":"44","author":"Grunert","year":"2014","journal-title":"Food Policy"},{"issue":"7541","key":"10.1093\/jn\/nxaa244_bib2","doi-asserted-by":"crossref","first-page":"92","DOI":"10.1038\/nature14232","article-title":"Dietary emulsifiers impact the mouse gut microbiota promoting colitis and metabolic syndrome.","volume":"519","author":"Chassaing","year":"2015","journal-title":"Nature"},{"issue":"8","key":"10.1093\/jn\/nxaa244_bib3","doi-asserted-by":"crossref","first-page":"1414","DOI":"10.1136\/gutjnl-2016-313099","article-title":"Dietary emulsifiers directly alter human microbiota composition and gene expression ex vivo potentiating intestinal inflammation.","volume":"66","author":"Chassaing","year":"2017","journal-title":"Gut"},{"issue":"3","key":"10.1093\/jn\/nxaa244_bib4","first-page":"1461","article-title":"Scientific opinion on dietary reference values for fats, including saturated fatty acids, polyunsaturated fatty acids,monounsaturated fatty acids, trans fatty acids, and cholesterol.","volume":"8","year":"2010","journal-title":"EFSA J"},{"issue":"11","key":"10.1093\/jn\/nxaa244_bib5","doi-asserted-by":"crossref","first-page":"1","DOI":"10.3390\/molecules22111964","article-title":"Phospholipids of animal and marine origin: structure, function, and anti-inflammatory properties.","volume":"22","author":"Lordan","year":"2017","journal-title":"Molecules"},{"key":"10.1093\/jn\/nxaa244_bib6","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1186\/1476-511X-11-3","article-title":"Health effects of dietary phospholipids.","volume":"11","author":"K\u00fcllenberg","year":"2012","journal-title":"Lipids Health Dis"},{"issue":"1","key":"10.1093\/jn\/nxaa244_bib7","doi-asserted-by":"crossref","first-page":"7","DOI":"10.1016\/j.lfs.2014.09.027","article-title":"Beneficial effects of phosphatidylcholine on high-fat diet-induced obesity, hyperlipidemia and fatty liver in mice.","volume":"118","author":"Lee","year":"2014","journal-title":"Life Sci"},{"issue":"9","key":"10.1093\/jn\/nxaa244_bib8","doi-asserted-by":"crossref","first-page":"461","DOI":"10.1016\/S0955-2863(00)00115-7","article-title":"Dietary soybean phosphatidylcholines lower lipidemia:mechanisms at the levels of intestine, endothelial cell, and hepato-biliary axis.","volume":"11","author":"Mastellone","year":"2000","journal-title":"J Nutr Biochem"},{"issue":"4","key":"10.1093\/jn\/nxaa244_bib9","doi-asserted-by":"crossref","first-page":"1218","DOI":"10.3390\/nu5041218","article-title":"Dyslipidemia in obesity: mechanisms and potential targets.","volume":"5","author":"Klop","year":"2013","journal-title":"Nutrients"},{"issue":"4","key":"10.1093\/jn\/nxaa244_bib10","doi-asserted-by":"crossref","first-page":"335","DOI":"10.1016\/j.jjcc.2015.12.001","article-title":"Postprandial hyperlipidemia as a potential residual risk factor.","volume":"67","author":"Nakamura","year":"2016","journal-title":"J Cardiol"},{"key":"10.1093\/jn\/nxaa244_bib11","doi-asserted-by":"crossref","first-page":"121","DOI":"10.1016\/j.biochi.2019.11.017","article-title":"Vegetable lecithins: a review of their compositional diversity, impact on lipid metabolism and potential in cardiometabolic disease prevention.","volume":"169","author":"Robert","year":"2020","journal-title":"Biochimie"},{"key":"10.1093\/jn\/nxaa244_bib12","series-title":"Food emulsifiers market report 2019\u20132025","first-page":"31","author":"Ahuja","year":"2019"},{"issue":"4","key":"10.1093\/jn\/nxaa244_bib13","first-page":"e04742","article-title":"Reevaluation of lecithins (E 322) as a food additive.","volume":"15","author":"Mortensen","year":"2017","journal-title":"EFSA J"},{"key":"10.1093\/jn\/nxaa244_bib14","first-page":"116","article-title":"Soybean polar lipids differently impact adipose tissue inflammation and the endotoxin transporters LBP and sCD14 in flaxseed vs. palm oil-rich diets.","volume":"43","author":"Lecomte","year":"2017","journal-title":"Biochem"},{"issue":"3","key":"10.1093\/jn\/nxaa244_bib15","doi-asserted-by":"crossref","first-page":"609","DOI":"10.1002\/mnfr.201500703","article-title":"Dietary emulsifiers from milk and soybean differently impact adiposity and inflammation in association with modulation of colonic goblet cells in high-fat fed mice.","volume":"60","author":"Lecomte","year":"2016","journal-title":"Mol Nutr Food Res"},{"issue":"4","key":"10.1093\/jn\/nxaa244_bib16","doi-asserted-by":"crossref","first-page":"325","DOI":"10.1007\/s11745-004-1236-0","article-title":"Dose effect of \u03b1-linolenic acid on PUFA conversion, bioavailability, and storage in the hamster.","volume":"39","author":"Morise","year":"2004","journal-title":"Lipids"},{"key":"10.1093\/jn\/nxaa244_bib17","unstructured":"ANSES. Actualisation des apports nutritionnels conseill\u00e9s pour les acides gras. 2011. Report No.: 2006-SA-0359."},{"key":"10.1093\/jn\/nxaa244_bib18","first-page":"1","article-title":"Fats and fatty acids in human nutrition. report of an expert consultation.","volume":"91","year":"2010","journal-title":"FAO Food Nutr Pap"},{"issue":"Suppl 2","key":"10.1093\/jn\/nxaa244_bib19","doi-asserted-by":"crossref","first-page":"95","DOI":"10.1016\/S0378-3782(01)00211-0","article-title":"Absorption and distribution of dietary fatty acids from different sources.","volume":"65","author":"Ram\u00edrez","year":"2001","journal-title":"Early Hum Dev"},{"issue":"5","key":"10.1093\/jn\/nxaa244_bib20","doi-asserted-by":"crossref","first-page":"1","DOI":"10.3390\/nu10050620","article-title":"Comparison of the incorporation of DHA in circulatory and neural tissue when provided as triacylglycerol (TAG), monoacylglycerol (MAG) or phospholipids (PL) provides new insight into fatty acid bioavailability.","volume":"10","author":"Destaillats","year":"2018","journal-title":"Nutrients"},{"key":"10.1093\/jn\/nxaa244_bib21","doi-asserted-by":"crossref","first-page":"511","DOI":"10.2147\/VHRM.S85165","article-title":"Comparison of bioavailability of krill oil versus fish oil and health effect.","volume":"11","author":"Ulven","year":"2015","journal-title":"Vasc Health Risk Manag"},{"issue":"97","key":"10.1093\/jn\/nxaa244_bib22","first-page":"1","article-title":"The mesenteric lymph duct cannulated rat model: application to the assessment of intestinal lymphatic drug transport.","author":"Trevaskis","year":"2015","journal-title":"J Vis Exp"},{"issue":"10","key":"10.1093\/jn\/nxaa244_bib23","first-page":"1349","article-title":"Techniques for the collection of lymph from the liver, small intestine, or thoracic duct of the rat.","volume":"33","author":"Bollman","year":"1948","journal-title":"J Lab Clin Med"},{"issue":"7","key":"10.1093\/jn\/nxaa244_bib24","doi-asserted-by":"crossref","first-page":"1026","DOI":"10.1017\/S000711451000454X","article-title":"Lymphatic absorption of \u03b1-linolenic acid in rats fed flaxseed oil-based emulsion.","volume":"105","author":"Cou\u00ebdelo","year":"2011","journal-title":"Br J Nutr"},{"issue":"2","key":"10.1093\/jn\/nxaa244_bib25","doi-asserted-by":"crossref","first-page":"227","DOI":"10.1016\/S0022-2275(20)38553-9","article-title":"Specific methylation of plasma nonesterified fatty acids in a one-step reaction.","volume":"29","author":"Lepage","year":"1988","journal-title":"J Lipid Res"},{"issue":"8","key":"10.1093\/jn\/nxaa244_bib26","doi-asserted-by":"crossref","first-page":"1770","DOI":"10.3945\/jn.115.212068","article-title":"Milk polar lipids affect in vitro digestive lipolysis and postprandial lipid metabolism in mice.","volume":"145","author":"Lecomte","year":"2015","journal-title":"J Nutr"},{"issue":"7","key":"10.1093\/jn\/nxaa244_bib27","doi-asserted-by":"crossref","first-page":"1093","DOI":"10.1007\/s11746-014-2455-9","article-title":"Mapping the chemical variability of vegetable lecithin..","volume":"91","author":"Nguyen","year":"2014","journal-title":"J Am Oil Chem Soc"},{"key":"10.1093\/jn\/nxaa244_bib28","doi-asserted-by":"crossref","first-page":"265","DOI":"10.1146\/annurev-nutr-071714-034338","article-title":"New insights into the regulation of chylomicron production.","volume":"35","author":"Dash","year":"2015","journal-title":"Annu Rev Nutr"},{"issue":"12","key":"10.1093\/jn\/nxaa244_bib29","doi-asserted-by":"crossref","first-page":"2696","DOI":"10.1016\/S0022-2275(20)37472-1","article-title":"Effects of particle size and number on the plasma clearance of chylomicrons and remnants.","volume":"37","author":"Martins","year":"1996","journal-title":"J Lipid Res"},{"issue":"12","key":"10.1093\/jn\/nxaa244_bib30","doi-asserted-by":"crossref","first-page":"775","DOI":"10.1038\/nrm3699","article-title":"The biophysics and cell biology of lipid droplets.","volume":"14","author":"Thiam","year":"2013","journal-title":"Nat Rev Mol Cell Biol"},{"issue":"3","key":"10.1093\/jn\/nxaa244_bib31","doi-asserted-by":"crossref","first-page":"565","DOI":"10.1079\/BJN2003946","article-title":"Enteral administration of soybean lecithin enhanced lymphatic absorption of triacylglycerol in rats.","volume":"90","author":"Nishimukai","year":"2003","journal-title":"Br J Nutr"},{"issue":"3","key":"10.1093\/jn\/nxaa244_bib32","doi-asserted-by":"crossref","first-page":"225","DOI":"10.1007\/s11745-013-3873-4","article-title":"Lymphatic transport of \u03b1-linolenic acid and its conversion to long chain n\u20133 fatty acids in rats fed microemulsions of linseed oil.","volume":"49","author":"Sugasini","year":"2014","journal-title":"Lipids"},{"issue":"9","key":"10.1093\/jn\/nxaa244_bib33","doi-asserted-by":"crossref","first-page":"2358","DOI":"10.1093\/jn\/131.9.2358","article-title":"Egg phosphatidylcholine decreases the lymphatic absorption of cholesterol in rats.","volume":"131","author":"Jiang","year":"2001","journal-title":"J Nutr"},{"issue":"5","key":"10.1093\/jn\/nxaa244_bib34","doi-asserted-by":"crossref","first-page":"1726","DOI":"10.1039\/C5FO00070J","article-title":"Impact of various emulsifiers on ALA bioavailability and chylomicron synthesis through changes in gastrointestinal lipolysis.","volume":"6","author":"Cou\u00ebdelo","year":"2015","journal-title":"Food Funct"},{"key":"10.1093\/jn\/nxaa244_bib35","article-title":"Impact m\u00e9tabolique des mati\u00e8res grasses alimentaires: vers le concept des lipides rapides\/lipides lents et l'effet matrice.","volume":"39","author":"Michalski","year":"2018","journal-title":"Lipid Nutri"},{"issue":"5","key":"10.1093\/jn\/nxaa244_bib36","doi-asserted-by":"crossref","first-page":"537","DOI":"10.1039\/c2fo10248j","article-title":"Coupling in vitro gastrointestinal lipolysis and Caco-2 cell cultures for testing the absorption of different food emulsions.","volume":"3","author":"Vors","year":"2012","journal-title":"Food Funct"},{"issue":"3","key":"10.1093\/jn\/nxaa244_bib37","doi-asserted-by":"crossref","first-page":"419","DOI":"10.1016\/0005-2760(86)90234-1","article-title":"Importance of human gastric lipase for intestinal lipolysis: an in vitro study.","volume":"879","author":"Gargouri","year":"1986","journal-title":"Biochim Biophys Acta"},{"key":"10.1093\/jn\/nxaa244_bib38","doi-asserted-by":"crossref","first-page":"90","DOI":"10.1016\/j.cocis.2009.11.006","article-title":"The influence of emulsion structure and stability on lipid digestion.","volume":"15","author":"Golding","year":"2010","journal-title":"Curr Opin Colloid Interface Sci"},{"issue":"6","key":"10.1093\/jn\/nxaa244_bib39","doi-asserted-by":"crossref","first-page":"1096","DOI":"10.1093\/ajcn\/70.6.1096","article-title":"Digestion and absorption of 2 fat emulsions with different droplet sizes in the human digestive tract.","volume":"70","author":"Armand","year":"1999","journal-title":"Am J Clin Nutr"},{"issue":"6","key":"10.1093\/jn\/nxaa244_bib40","doi-asserted-by":"crossref","first-page":"324","DOI":"10.1051\/ocl.2011.0415","article-title":"Organisation structurale et mol\u00e9culaire des lipides dans les aliments: impacts possibles sur leur digestion et leur assimilation par l'Homme.","volume":"18","author":"Raynal-Ljutovac","year":"2011","journal-title":"OCL"},{"issue":"4","key":"10.1093\/jn\/nxaa244_bib41","doi-asserted-by":"crossref","first-page":"354","DOI":"10.1016\/j.plipres.2013.04.004","article-title":"Multiscale structures of lipids in foods as parameters affecting fatty acid bioavailability and lipid metabolism.","volume":"52","author":"Michalski","year":"2013","journal-title":"Prog Lipid Res"},{"issue":"11","key":"10.1093\/jn\/nxaa244_bib42","doi-asserted-by":"crossref","first-page":"15401","DOI":"10.3390\/ijms131115401","article-title":"Marine omega-3 phospholipids:metabolism and biological activities.","volume":"13","author":"Burri","year":"2012","journal-title":"Int J Mol Sci"},{"key":"10.1093\/jn\/nxaa244_bib43","first-page":"1","article-title":"In vitro lipolysis and lymphatic absorption of n\u20133 long-chain polyunsaturated fatty acids in the rat: influence of the molecular lipid species as carrier.","author":"Sehl","year":"2019","journal-title":"Br J Nutr"},{"issue":"5","key":"10.1093\/jn\/nxaa244_bib44","doi-asserted-by":"crossref","first-page":"551","DOI":"10.1007\/s11745-003-1341-0","article-title":"Marine lipid-based liposomes increase in vivo FA bioavailability.","volume":"38","author":"Cansell","year":"2003","journal-title":"Lipids"},{"issue":"8","key":"10.1093\/jn\/nxaa244_bib45","doi-asserted-by":"crossref","first-page":"465","DOI":"10.1007\/s00394-009-0037-7","article-title":"Hepatic lipid metabolism response to dietary fatty acids is differently modulated by PPARalpha in male and female mice.","volume":"48","author":"Morise","year":"2009","journal-title":"Eur J Nutr"},{"issue":"3","key":"10.1093\/jn\/nxaa244_bib46","doi-asserted-by":"crossref","first-page":"161","DOI":"10.1016\/j.plefa.2006.05.013","article-title":"Metabolism of \u03b1-linolenic acid in humans.","volume":"75","author":"Burdge","year":"2006","journal-title":"Prostaglandins Leukot Essent Fatty Acids"},{"issue":"4","key":"10.1093\/jn\/nxaa244_bib47","doi-asserted-by":"crossref","first-page":"601","DOI":"10.1016\/S0022-2275(20)41168-X","article-title":"Interconversion of alpha-linolenic acid in rat intestinal mucosa: studies in vivo and in isolated villus and crypt cells.","volume":"35","author":"Chen","year":"1994","journal-title":"J Lipid Res"},{"issue":"4","key":"10.1093\/jn\/nxaa244_bib48","doi-asserted-by":"crossref","first-page":"411","DOI":"10.1079\/BJN2002689","article-title":"Conversion of alpha-linolenic acid to eicosapentaenoic, docosapentaenoic and docosahexaenoic acids in young women.","volume":"88","author":"Burdge","year":"2002","journal-title":"Br J Nutr"},{"issue":"3","key":"10.1093\/jn\/nxaa244_bib49","doi-asserted-by":"crossref","first-page":"140","DOI":"10.1038\/nrendo.2017.161","article-title":"Animal models of obesity and diabetes mellitus.","volume":"14","author":"Kleinert","year":"2018","journal-title":"Nat Rev Endocrinol"},{"issue":"1","key":"10.1093\/jn\/nxaa244_bib50","doi-asserted-by":"crossref","first-page":"38","DOI":"10.1016\/0005-2760(88)90147-6","article-title":"Lingual and gastric lipases: species differences in the origin of prepancreatic digestive lipases and in the localization of gastric lipase.","volume":"959","author":"DeNigris","year":"1988","journal-title":"Biochim Biophys Acta"},{"issue":"5","key":"10.1093\/jn\/nxaa244_bib51","doi-asserted-by":"crossref","first-page":"351","DOI":"10.1002\/bdd.2510160502","article-title":"Comparison of the gastrointestinal anatomy, physiology, and biochemistry of humans and commonly used laboratory animals.","volume":"16","author":"Kararli","year":"1995","journal-title":"Biopharm Drug Dispos"},{"issue":"4","key":"10.1093\/jn\/nxaa244_bib52","doi-asserted-by":"crossref","first-page":"329","DOI":"10.1111\/nbu.12408","article-title":"Food additives: assessing the impact of exposure to permitted emulsifiers on bowel and metabolic health\u2014introducing the FADiets study.","volume":"44","author":"Partridge","year":"2019","journal-title":"Nutr Bull"}],"container-title":["The Journal of Nutrition"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S002231662202363X?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S002231662202363X?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/academic.oup.com\/jn\/article-pdf\/150\/11\/2900\/34390913\/nxaa244.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"http:\/\/academic.oup.com\/jn\/article-pdf\/150\/11\/2900\/34390913\/nxaa244.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,5]],"date-time":"2023-10-05T08:08:08Z","timestamp":1696493288000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S002231662202363X"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,11]]},"references-count":52,"journal-issue":{"issue":"11","published-print":{"date-parts":[[2020,11]]}},"alternative-id":["S002231662202363X"],"URL":"https:\/\/doi.org\/10.1093\/jn\/nxaa244","relation":{},"ISSN":["0022-3166"],"issn-type":[{"value":"0022-3166","type":"print"}],"subject":[],"published":{"date-parts":[[2020,11]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Rapeseed Lecithin Increases Lymphatic Lipid Output and \u03b1-Linolenic Acid Bioavailability in Rats","name":"articletitle","label":"Article Title"},{"value":"The Journal of Nutrition","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1093\/jn\/nxaa244","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2020 American Society for Nutrition. Published by Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}]}}