{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,5,13]],"date-time":"2025-05-13T23:59:23Z","timestamp":1747180763129,"version":"3.40.5"},"reference-count":17,"publisher":"Elsevier BV","issue":"3","license":[{"start":{"date-parts":[[2021,3,1]],"date-time":"2021-03-01T00:00:00Z","timestamp":1614556800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2023,1,17]],"date-time":"2023-01-17T00:00:00Z","timestamp":1673913600000},"content-version":"vor","delay-in-days":687,"URL":"http:\/\/www.elsevier.com\/open-access\/userlicense\/1.0\/"}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["The Journal of Nutrition"],"published-print":{"date-parts":[[2021,3]]},"DOI":"10.1093\/jn\/nxaa422","type":"journal-article","created":{"date-parts":[[2020,12,3]],"date-time":"2020-12-03T20:17:37Z","timestamp":1607026657000},"page":"465-467","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":1,"title":["Towards an Integrated Mathematical Model of Nutrient Metabolism: Linking \u03b2-Carotene and Vitamin A"],"prefix":"10.1016","volume":"151","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-1781-9242","authenticated-orcid":false,"given":"Bryan M","family":"Gannon","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1093\/jn\/nxaa422_bib1","doi-asserted-by":"crossref","first-page":"158754","DOI":"10.1016\/j.bbalip.2020.158754","article-title":"Biology of carotenoids in mammals.","volume":"1865","author":"von Lintig","year":"2020","journal-title":"Biochim Biophys Acta Mol Cell Biol Lipids."},{"key":"10.1093\/jn\/nxaa422_bib2","doi-asserted-by":"crossref","first-page":"e528","DOI":"10.1016\/S2214-109X(15)00039-X","article-title":"Trends and mortality effects of vitamin A deficiency in children in 138 low-income and middle-income countries between 1991 and 2013: a pooled analysis of population-based surveys.","volume":"3","author":"Stevens","year":"2015","journal-title":"Lancet Glob Health."},{"key":"10.1093\/jn\/nxaa422_bib3","doi-asserted-by":"crossref","first-page":"500","DOI":"10.1126\/science.abc4765","article-title":"COVID-19 risks to global food security.","volume":"369","author":"Laborde","year":"2020","journal-title":"Science."},{"key":"10.1093\/jn\/nxaa422_bib4","doi-asserted-by":"crossref","first-page":"S75","DOI":"10.1177\/0379572116630481","article-title":"A changing landscape for vitamin A programs: implications for optimal intervention packages, program monitoring, and safety.","volume":"37","author":"Klemm","year":"2016","journal-title":"Food Nutr Bull."},{"key":"10.1093\/jn\/nxaa422_bib5","doi-asserted-by":"crossref","first-page":"1816s","DOI":"10.3945\/jn.115.229708","article-title":"Biomarkers of Nutrition for Development (BOND)\u2014vitamin A review.","volume":"146","author":"Tanumihardjo","year":"2016","journal-title":"J Nutr."},{"key":"10.1093\/jn\/nxaa422_bib6","doi-asserted-by":"crossref","first-page":"2268S","DOI":"10.3945\/jn.109.119024","article-title":"Beta-carotene is an important vitamin A source for humans.","volume":"140","author":"Grune","year":"2010","journal-title":"J Nutr."},{"key":"10.1093\/jn\/nxaa422_bib7","doi-asserted-by":"crossref","first-page":"18","DOI":"10.1016\/j.abb.2018.06.001","article-title":"Carotenoids in human nutrition and health.","volume":"652","author":"Eggersdorfer","year":"2018","journal-title":"Arch Biochem Biophys."},{"key":"10.1093\/jn\/nxaa422_bib8","doi-asserted-by":"crossref","first-page":"nzaa142","DOI":"10.1093\/cdn\/nzaa142","article-title":"Vitamin A requirements in pregnancy and lactation.","volume":"4","author":"Gannon","year":"2020","journal-title":"Curr Dev Nutr."},{"key":"10.1093\/jn\/nxaa422_bib9","doi-asserted-by":"crossref","first-page":"nzaa096","DOI":"10.1093\/cdn\/nzaa096","article-title":"Our current Dietary Reference Intakes for vitamin A\u2014now 20 years old.","volume":"4","author":"Ross","year":"2020","journal-title":"Curr Dev Nutr."},{"key":"10.1093\/jn\/nxaa422_bib10","article-title":"A compartmental model describing the kinetics of \u03b2-carotene and \u03b2-carotene-derived retinol in healthy older adults.","author":"Green","year":"2020","journal-title":"J Nutr."},{"key":"10.1093\/jn\/nxaa422_bib11","doi-asserted-by":"crossref","first-page":"259","DOI":"10.1093\/ajcn\/78.2.259","article-title":"Short-term (intestinal) and long-term (postintestinal) conversion of beta-carotene to retinol in adults as assessed by a stable-isotope reference method.","volume":"78","author":"Tang","year":"2003","journal-title":"Am J Clin Nutr."},{"key":"10.1093\/jn\/nxaa422_bib12","doi-asserted-by":"crossref","first-page":"971","DOI":"10.1093\/jn\/138.5.971","article-title":"Kinetic analysis shows that vitamin A disposal rate in humans is positively correlated with vitamin A stores.","volume":"138","author":"Cifelli","year":"2008","journal-title":"J Nutr."},{"key":"10.1093\/jn\/nxaa422_bib13","doi-asserted-by":"crossref","first-page":"2065","DOI":"10.1093\/jn\/nxz112","article-title":"Addition of vitamin A intake data during compartmental modeling of retinol kinetics in theoretical humans leads to accurate prediction of vitamin A total body stores and kinetic parameters in studies of reasonable duration.","volume":"149","author":"Ford","year":"2019","journal-title":"J Nutr."},{"key":"10.1093\/jn\/nxaa422_bib14","doi-asserted-by":"crossref","first-page":"904","DOI":"10.1194\/jlr.M600528-JLR200","article-title":"Model-based compartmental analysis indicates a reduced mobilization of hepatic vitamin A during inflammation in rats.","volume":"48","author":"Gieng","year":"2007","journal-title":"J Lipid Res."},{"key":"10.1093\/jn\/nxaa422_bib15","doi-asserted-by":"crossref","first-page":"51","DOI":"10.1002\/mas.20108","article-title":"Mass spectrometry-based metabolomics.","volume":"26","author":"Dettmer","year":"2007","journal-title":"Mass Spectrom Rev."},{"key":"10.1093\/jn\/nxaa422_bib16","doi-asserted-by":"crossref","first-page":"855","DOI":"10.1038\/nrg2897","article-title":"Phenomics: the next challenge.","volume":"11","author":"Houle","year":"2010","journal-title":"Nat Rev Genet."},{"year":"2011","series-title":"Toward precision medicine: building a knowledge network for biomedical research and a new taxonomy of disease.","key":"10.1093\/jn\/nxaa422_bib17"}],"container-title":["The Journal of Nutrition"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S002231662200075X?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S002231662200075X?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/academic.oup.com\/jn\/article-pdf\/151\/3\/465\/36547429\/nxaa422.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"http:\/\/academic.oup.com\/jn\/article-pdf\/151\/3\/465\/36547429\/nxaa422.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,6,13]],"date-time":"2023-06-13T16:46:06Z","timestamp":1686674766000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S002231662200075X"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,3]]},"references-count":17,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2021,3]]}},"alternative-id":["S002231662200075X"],"URL":"https:\/\/doi.org\/10.1093\/jn\/nxaa422","relation":{},"ISSN":["0022-3166"],"issn-type":[{"type":"print","value":"0022-3166"}],"subject":[],"published":{"date-parts":[[2021,3]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Towards an Integrated Mathematical Model of Nutrient Metabolism: Linking \u03b2-Carotene and Vitamin A","name":"articletitle","label":"Article Title"},{"value":"The Journal of Nutrition","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1093\/jn\/nxaa422","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2021 American Society for Nutrition. Published by Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}]}}