{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,1]],"date-time":"2026-11-01T04:04:26Z","timestamp":1793505866296,"version":"4.5.0"},"reference-count":30,"publisher":"Elsevier BV","issue":"7","license":[{"start":{"date-parts":[[2021,7,1]],"date-time":"2021-07-01T00:00:00Z","timestamp":1625097600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2023,2,6]],"date-time":"2023-02-06T00:00:00Z","timestamp":1675641600000},"content-version":"vor","delay-in-days":585,"URL":"http:\/\/www.elsevier.com\/open-access\/userlicense\/1.0\/"}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["The Journal of Nutrition"],"published-print":{"date-parts":[[2021,7]]},"DOI":"10.1093\/jn\/nxab069","type":"journal-article","created":{"date-parts":[[2021,2,24]],"date-time":"2021-02-24T20:11:41Z","timestamp":1614197501000},"page":"2075-2083","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":18,"title":["Predicting Protein and Fat Content in Human Donor Milk Using Machine Learning"],"prefix":"10.1016","volume":"151","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-1712-4179","authenticated-orcid":false,"given":"Rachel K","family":"Wong","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michael A","family":"Pitino","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rafid","family":"Mahmood","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ian Yihang","family":"Zhu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Debbie","family":"Stone","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6331-091X","authenticated-orcid":false,"given":"Deborah L","family":"O'Connor","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8091-5742","authenticated-orcid":false,"given":"Sharon","family":"Unger","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4128-1692","authenticated-orcid":false,"given":"Timothy C Y","family":"Chan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1093\/jn\/nxab069_bib1","doi-asserted-by":"crossref","first-page":"502","DOI":"10.1111\/j.1542-2011.2012.00267.x","article-title":"Nonprofit human milk banking in the United States.","volume":"58","author":"Updegrove","year":"2013","journal-title":"J Midwifery Womens Health."},{"key":"10.1093\/jn\/nxab069_bib2","doi-asserted-by":"crossref","first-page":"57","DOI":"10.1038\/jp.2008.117","article-title":"Role of human milk in extremely low birth weight infants\u2019 risk of necrotizing enterocolitis or death.","volume":"29","author":"Meinzen-Derr","year":"2009","journal-title":"J Perinatol."},{"key":"10.1093\/jn\/nxab069_bib3","first-page":"CD002971","article-title":"Formula versus donor breast milk for feeding preterm or low birth weight infants.","volume":"4","author":"Quigley","year":"2018","journal-title":"Cochrane Database Syst Rev."},{"key":"10.1093\/jn\/nxab069_bib4","doi-asserted-by":"crossref","first-page":"269","DOI":"10.1097\/MCO.0000000000000160","article-title":"Human milk pasteurization: benefits and risks.","volume":"18","author":"O'Connor","year":"2015","journal-title":"Curr Opin Clin Nutr Metab Care."},{"key":"10.1093\/jn\/nxab069_bib5","doi-asserted-by":"crossref","first-page":"e0210610","DOI":"10.1371\/journal.pone.0210610","article-title":"Macronutrient variability in human milk from donors to a milk bank: Implications for feeding preterm infants.","volume":"14","author":"John","year":"2019","journal-title":"PLoS One."},{"key":"10.1093\/jn\/nxab069_bib6","doi-asserted-by":"crossref","first-page":"F539","DOI":"10.1136\/archdischild-2013-304422","article-title":"Macronutrient content of donor human breast milk.","volume":"98","author":"Cooper","year":"2013","journal-title":"Arch Dis Child Fetal Neonatal Ed."},{"key":"10.1093\/jn\/nxab069_bib7","doi-asserted-by":"crossref","first-page":"76","DOI":"10.3389\/fped.2019.00076","article-title":"Fortification of human milk for preterm infants: update and recommendations of the European Milk Bank Association (EMBA) Working Group on Human Milk Fortification.","volume":"7","author":"Arslanoglu","year":"2019","journal-title":"Front Pediatr."},{"key":"10.1093\/jn\/nxab069_bib8","doi-asserted-by":"crossref","first-page":"1155","DOI":"10.1017\/S0007114519002228","article-title":"Macronutrient content of donor milk from a regional human milk bank: variation with donor mother\u2013infant characteristics.","volume":"122","author":"Mills","year":"2019","journal-title":"Br J Nutr."},{"key":"10.1093\/jn\/nxab069_bib9","doi-asserted-by":"crossref","first-page":"529S","DOI":"10.3945\/ajcn.112.042689","article-title":"Variability in human milk composition: benefit of individualized fortification in very-low-birth-weight infants.","volume":"98","author":"de Halleux","year":"2013","journal-title":"Am J Clin Nutr."},{"key":"10.1093\/jn\/nxab069_bib10","doi-asserted-by":"crossref","first-page":"1133","DOI":"10.1136\/bmj.39034.651563.80","article-title":"Donor breast milk banking.","volume":"333","author":"Modi","year":"2006","journal-title":"BMJ."},{"key":"10.1093\/jn\/nxab069_bib11","doi-asserted-by":"crossref","first-page":"370","DOI":"10.1089\/bfm.2020.0046","article-title":"Fat and protein variability in donor human milk and associations with milk banking processes.","volume":"15","author":"Friend","year":"2020","journal-title":"Breastfeed Med."},{"key":"10.1093\/jn\/nxab069_bib12","doi-asserted-by":"crossref","first-page":"54","DOI":"10.1016\/j.jpeds.2019.07.042","article-title":"Effect of pooling practices and time postpartum of milk donations on the energy, macronutrient, and zinc concentrations of resultant donor human milk pools.","volume":"214","author":"Young","year":"2019","journal-title":"J Pediatr."},{"key":"10.1093\/jn\/nxab069_bib13","doi-asserted-by":"crossref","first-page":"1884","DOI":"10.3390\/nu11081884","article-title":"Macronutrient analysis of target-pooled donor breast milk and corresponding growth in very low birth weight infants.","volume":"11","author":"Fu TT","year":"2019","journal-title":"Nutrients."},{"key":"10.1093\/jn\/nxab069_bib14","doi-asserted-by":"crossref","first-page":"21","DOI":"10.1186\/s13690-018-0264-6","article-title":"Bayesian Gaussian regression analysis of malnutrition for children under five years of age in Ethiopia, EMDHS 2014.","volume":"76","author":"Mohammed","year":"2018","journal-title":"Arch Public Health."},{"key":"10.1093\/jn\/nxab069_bib15","doi-asserted-by":"crossref","DOI":"10.1007\/978-981-15-6318-8_7","article-title":"Nutritional status prediction in neonate using machine learning techniques: a comparative study.","author":"Hussain","year":"2020"},{"key":"10.1093\/jn\/nxab069_bib16","doi-asserted-by":"crossref","first-page":"1179","DOI":"10.1017\/S0007114509371755","article-title":"Growth and nutrient intake among very-low-birth-weight infants fed fortified human milk during hospitalisation.","volume":"102","author":"Henriksen","year":"2009","journal-title":"Br J Nutr."},{"key":"10.1093\/jn\/nxab069_bib17","doi-asserted-by":"crossref","first-page":"229","DOI":"10.1097\/00005176-199008000-00013","article-title":"Variation in macronutrients in human bank milk: influencing factors and implications for human milk banking.","volume":"11","author":"Michaelsen","year":"1990","journal-title":"J Pediatr Gastroenterol Nutr."},{"key":"10.1093\/jn\/nxab069_bib18","doi-asserted-by":"crossref","first-page":"49","DOI":"10.1186\/s13006-020-00291-y","article-title":"Circadian changes in the composition of human milk macronutrients depending on pregnancy duration: a cross-sectional study.","volume":"15","author":"Paulaviciene","year":"2020","journal-title":"Int Breastfeed J."},{"key":"10.1093\/jn\/nxab069_bib19","doi-asserted-by":"crossref","first-page":"421","DOI":"10.3390\/nu12020421","article-title":"Role of daily milk volume and period of lactation in nutrient content of human milk: results from a prospective study.","volume":"12","author":"Rigourd","year":"2020","journal-title":"Nutrients."},{"key":"10.1093\/jn\/nxab069_bib20","first-page":"2825","article-title":"Scikit-learn: machine learning in Python.","volume":"12","author":"Pedregosa","year":"2011","journal-title":"J Mach Learn Res."},{"key":"10.1093\/jn\/nxab069_bib21","doi-asserted-by":"crossref","first-page":"216","DOI":"10.1186\/1471-2431-14-216","article-title":"A systematic review and meta-analysis of the nutrient content of preterm and term breast milk.","volume":"14","author":"Gidrewicz","year":"2014","journal-title":"BMC Pediatr."},{"key":"10.1093\/jn\/nxab069_bib22","doi-asserted-by":"crossref","first-page":"1885","DOI":"10.1162\/089976699300016007","article-title":"Combined 5x2 cv F Test for comparing supervised classification learning algorithms.","volume":"11","author":"Alpayd\u0131n","year":"1999","journal-title":"Nerual Comput."},{"key":"10.1093\/jn\/nxab069_bib23","doi-asserted-by":"crossref","first-page":"1340","DOI":"10.1093\/bioinformatics\/btq134","article-title":"Permutation importance: a corrected feature importance measure.","volume":"26","author":"Altmann","year":"2010","journal-title":"Bioinformatics."},{"key":"10.1093\/jn\/nxab069_bib24","article-title":"Miris human milk analyzer user manual.","year":"2017"},{"key":"10.1093\/jn\/nxab069_bib25","doi-asserted-by":"crossref","first-page":"nzz116","DOI":"10.1093\/cdn\/nzz116","article-title":"Accuracy and reliability of infrared analyzers for measuring human milk macronutrients in a milk bank setting.","volume":"3","author":"Perrin","year":"2019","journal-title":"Curr Dev Nutr."},{"key":"10.1093\/jn\/nxab069_bib26","doi-asserted-by":"crossref","first-page":"579115","DOI":"10.3389\/fnut.2020.579115","article-title":"Milk bank pooling practices impact concentrations and variability of bioactive components of donor human milk.","volume":"7","author":"Young","year":"2020","journal-title":"Front Nutr."},{"key":"10.1093\/jn\/nxab069_bib27","doi-asserted-by":"crossref","first-page":"1302","DOI":"10.1080\/14767058.2016.1212329","article-title":"The impact of maternal- and neonatal-associated factors on human milk's macronutrients and energy.","volume":"30","author":"Dritsakou","year":"2017","journal-title":"J Matern Fetal Neonatal Med."},{"key":"10.1093\/jn\/nxab069_bib28","doi-asserted-by":"crossref","first-page":"1385","DOI":"10.1080\/14767058.2017.1315660","article-title":"Content fat and calorie of human milk is affected by interactions between maternal age and body mass index.","volume":"31","author":"Hahn","year":"2018","journal-title":"J Matern Fetal Neonatal Med."},{"key":"10.1093\/jn\/nxab069_bib29","doi-asserted-by":"crossref","first-page":"47","DOI":"10.1177\/0890334413508237","article-title":"Donor human milk bank data collection in North America: an assessment of current status and future needs.","volume":"30","author":"Brownell","year":"2014","journal-title":"J Hum Lact."},{"key":"10.1093\/jn\/nxab069_bib30","doi-asserted-by":"crossref","first-page":"137","DOI":"10.1016\/j.jada.2008.10.008","article-title":"Macronutrient analysis of a nationwide sample of donor breast milk.","volume":"109","author":"Wojcik","year":"2009","journal-title":"J Am Diet Assoc."}],"container-title":["The Journal of Nutrition"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0022316622002437?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0022316622002437?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/academic.oup.com\/jn\/article-pdf\/151\/7\/2075\/38844589\/nxab069.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"http:\/\/academic.oup.com\/jn\/article-pdf\/151\/7\/2075\/38844589\/nxab069.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,6,13]],"date-time":"2023-06-13T21:12:51Z","timestamp":1686690771000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0022316622002437"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,7]]},"references-count":30,"journal-issue":{"issue":"7","published-print":{"date-parts":[[2021,7]]}},"alternative-id":["S0022316622002437"],"URL":"https:\/\/doi.org\/10.1093\/jn\/nxab069","relation":{},"ISSN":["0022-3166"],"issn-type":[{"value":"0022-3166","type":"print"}],"subject":[],"published":{"date-parts":[[2021,7]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Predicting Protein and Fat Content in Human Donor Milk Using Machine Learning","name":"articletitle","label":"Article Title"},{"value":"The Journal of Nutrition","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1093\/jn\/nxab069","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2021 American Society for Nutrition. Published by Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}]}}