{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,10]],"date-time":"2026-09-10T21:52:12Z","timestamp":1789077132305,"version":"build-2803163510"},"reference-count":87,"publisher":"Elsevier BV","issue":"4","license":[{"start":{"date-parts":[[2018,4,1]],"date-time":"2018-04-01T00:00:00Z","timestamp":1522540800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2023,1,19]],"date-time":"2023-01-19T00:00:00Z","timestamp":1674086400000},"content-version":"vor","delay-in-days":1754,"URL":"http:\/\/www.elsevier.com\/open-access\/userlicense\/1.0\/"}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["The Journal of Nutrition"],"published-print":{"date-parts":[[2018,4]]},"DOI":"10.1093\/jn\/nxy021","type":"journal-article","created":{"date-parts":[[2018,4,11]],"date-time":"2018-04-11T00:24:07Z","timestamp":1523406247000},"page":"650-657","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":51,"title":["Aspartame Consumption for 12 Weeks Does Not Affect Glycemia, Appetite, or Body Weight of Healthy, Lean Adults in a Randomized Controlled Trial"],"prefix":"10.1016","volume":"148","author":[{"given":"Kelly A","family":"Higgins","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Robert V","family":"Considine","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Richard D","family":"Mattes","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1093\/jn\/nxy021_bib1","doi-asserted-by":"crossref","DOI":"10.1016\/j.jand.2012.07.009","article-title":"Use of caloric and noncaloric sweeteners in US consumer packaged foods, 2005\u20132009","volume":"112","author":"Ng","year":"2012","journal-title":"J Acad Nutr Diet"},{"key":"10.1093\/jn\/nxy021_bib2","doi-asserted-by":"crossref","DOI":"10.1161\/CIRCRESAHA.115.306825","article-title":"Epidemiology of obesity and diabetes and their cardiovascular complications","volume":"118","author":"Bhupathiraju","year":"2016","journal-title":"Circ Res"},{"key":"10.1093\/jn\/nxy021_bib3","doi-asserted-by":"crossref","first-page":"S47","DOI":"10.2337\/dc16-S009","article-title":"Obesity management for the treatment of type 2 diabetes","volume":"39","year":"2016","journal-title":"Diabetes Care"},{"key":"10.1093\/jn\/nxy021_bib4","doi-asserted-by":"crossref","DOI":"10.3945\/ajcn.112.034751","article-title":"Low-calorie sweetener consumption is increasing in the United States","volume":"96","author":"Sylvetsky","year":"2012","journal-title":"Am J Clin Nutr"},{"key":"10.1093\/jn\/nxy021_bib5","doi-asserted-by":"crossref","first-page":"294","DOI":"10.1111\/j.2047-6310.2013.00153.x","article-title":"Trends in purchases and intake of foods and beverages containing caloric and low-calorie sweeteners over the last decade in the United States","volume":"8","author":"Piernas","year":"2013","journal-title":"Pediatr Obes"},{"key":"10.1093\/jn\/nxy021_bib6","doi-asserted-by":"crossref","first-page":"71","DOI":"10.1186\/s12986-016-0129-3","article-title":"Hormonal responses to non-nutritive sweeteners in water and diet soda","volume":"13","author":"Sylvetsky","year":"2016","journal-title":"Nutr Metab (Lond)"},{"key":"10.1093\/jn\/nxy021_bib7","doi-asserted-by":"crossref","DOI":"10.1016\/j.jand.2016.11.004","article-title":"Consumption of low-calorie sweeteners among children and adults in the United States","volume":"117","author":"Sylvetsky","year":"2017","journal-title":"J Acad Nutr Diet"},{"key":"10.1093\/jn\/nxy021_bib8","doi-asserted-by":"crossref","DOI":"10.3945\/ajcn.116.144402","article-title":"Widespread sucralose exposure in a randomized clinical trial in healthy young adults","volume":"105","author":"Sylvetsky","year":"2017","journal-title":"Am J Clin Nutr"},{"key":"10.1093\/jn\/nxy021_bib9","doi-asserted-by":"crossref","DOI":"10.3945\/ajcn.113.082826","article-title":"Low-calorie sweeteners and body weight and composition: a meta-analysis of randomized controlled trials and prospective cohort studies","volume":"100","author":"Miller","year":"2014","journal-title":"Am J Clin Nutr"},{"key":"10.1093\/jn\/nxy021_bib10","doi-asserted-by":"crossref","DOI":"10.1038\/ijo.2015.177","article-title":"Does low-energy sweetener consumption affect energy intake and body weight? A systematic review, including meta-analyses, of the evidence from human and animal studies","volume":"40","author":"Rogers","year":"2016","journal-title":"Int J Obes (Lond)"},{"key":"10.1093\/jn\/nxy021_bib11","doi-asserted-by":"crossref","DOI":"10.1002\/oby.20834","article-title":"Low\/no calorie sweetened beverage consumption in the National Weight Control Registry","volume":"22","author":"Catenacci","year":"2014","journal-title":"Obesity (Silver Spring)"},{"key":"10.1093\/jn\/nxy021_bib12","doi-asserted-by":"crossref","DOI":"10.1161\/CIR.0b013e31825c42ee","article-title":"Nonnutritive sweeteners: current use and health perspectives: a scientific statement from the American Heart Association and the American Diabetes Association","volume":"126","author":"Gardner","year":"2012","journal-title":"Circulation"},{"key":"10.1093\/jn\/nxy021_bib13","doi-asserted-by":"crossref","DOI":"10.1016\/j.jand.2012.03.009","article-title":"Position of the Academy of Nutrition and Dietetics: use of nutritive and nonnutritive sweeteners","volume":"112","author":"Fitch","year":"2012","journal-title":"J Acad Nutr Diet"},{"key":"10.1093\/jn\/nxy021_bib14","article-title":"Canadian Diabetes Association National Nutrition Committee technical review: non-nutritive intense sweeteners in diabetes management","volume":"28","author":"Gougeon","year":"2004","journal-title":"Can J Diabetes"},{"key":"10.1093\/jn\/nxy021_bib15","doi-asserted-by":"crossref","first-page":"37","DOI":"10.1016\/j.appet.2010.03.009","article-title":"Effects of stevia, ASP, and sucrose on food intake, satiety, and postprandial glucose and insulin levels","volume":"55","author":"Anton","year":"2010","journal-title":"Appetite"},{"key":"10.1093\/jn\/nxy021_bib16","article-title":"Effect of Stevia rebaudiana on glucose tolerance in normal adult humans","volume":"19","author":"Curi","year":"1986","journal-title":"Braz J Med Biol Res"},{"key":"10.1093\/jn\/nxy021_bib17","doi-asserted-by":"crossref","DOI":"10.3390\/nu6104389","article-title":"Consumption of low-calorie sweeteners among U.S. adults is associated with higher Healthy Eating Index (HEI 2005) scores and more physical activity","volume":"6","author":"Drewnowski","year":"2014","journal-title":"Nutrients"},{"key":"10.1093\/jn\/nxy021_bib18","first-page":"38","article-title":"Hitting the health and wellness target","volume":"71","author":"Kuhn","year":"2017","journal-title":"Food Technol"},{"key":"10.1093\/jn\/nxy021_bib19","doi-asserted-by":"crossref","DOI":"10.1016\/j.nlm.2013.07.014","article-title":"An application of Pavlovian principles to the problems of obesity and cognitive decline","volume":"108","author":"Davidson","year":"2014","journal-title":"Neurobiol Learn Mem"},{"key":"10.1093\/jn\/nxy021_bib20","doi-asserted-by":"crossref","DOI":"10.1016\/j.physbeh.2016.04.047","article-title":"Low-calorie sweetener use and energy balance: results from experimental studies in animals, and large-scale prospective studies in humans","volume":"164","author":"Fowler","year":"2016","journal-title":"Physiol Behav"},{"key":"10.1093\/jn\/nxy021_bib21","doi-asserted-by":"crossref","DOI":"10.1038\/oby.2008.284","article-title":"Fueling the obesity epidemic? Artificially sweetened beverage use and long-term weight gain","volume":"16","author":"Fowler","year":"2008","journal-title":"Obesity (Silver Spring)"},{"key":"10.1093\/jn\/nxy021_bib22","doi-asserted-by":"crossref","first-page":"82","DOI":"10.1016\/j.appet.2014.08.003","article-title":"The effect of non-caloric sweeteners on cognition, choice, and post-consumption satisfaction","volume":"83","author":"Hill","year":"2014","journal-title":"Appetite"},{"key":"10.1093\/jn\/nxy021_bib23","doi-asserted-by":"crossref","first-page":"e109841","DOI":"10.1371\/journal.pone.0109841","article-title":"Low-dose ASP consumption differentially affects gut microbiota-host metabolic interactions in the diet-induced obese rat","volume":"9","author":"Palmnas","year":"2014","journal-title":"PLoS One"},{"key":"10.1093\/jn\/nxy021_bib24","doi-asserted-by":"crossref","DOI":"10.1097\/MCO.0b013e3283468e7e","article-title":"Non-nutritive sweeteners, energy balance, and glucose homeostasis","volume":"14","author":"Pepino","year":"2011","journal-title":"Curr Opin Clin Nutr Metab Care"},{"key":"10.1093\/jn\/nxy021_bib25","doi-asserted-by":"crossref","first-page":"e20153603","DOI":"10.1542\/peds.2015-3603","article-title":"Early exposure to nonnutritive sweeteners and long-term metabolic health: a systematic review","volume":"137","author":"Reid","year":"2016","journal-title":"Pediatrics"},{"key":"10.1093\/jn\/nxy021_bib26","doi-asserted-by":"crossref","DOI":"10.1093\/chemse\/bjs053","article-title":"Rationale for further medical and health research on high-potency sweeteners","volume":"37","author":"Schiffman","year":"2012","journal-title":"Chem Senses"},{"key":"10.1093\/jn\/nxy021_bib27","doi-asserted-by":"crossref","DOI":"10.1038\/nature13793","article-title":"Artificial sweeteners induce glucose intolerance by altering the gut microbiota","volume":"514","author":"Suez","year":"2014","journal-title":"Nature"},{"key":"10.1093\/jn\/nxy021_bib28","doi-asserted-by":"crossref","DOI":"10.1016\/j.tem.2013.05.005","article-title":"Artificial sweeteners produce the counterintuitive effect of inducing metabolic derangements","volume":"24","author":"Swithers","year":"2013","journal-title":"Trends Endocrinol Metab"},{"key":"10.1093\/jn\/nxy021_bib29","article-title":"Gain weight by \u201cgoing diet?\u201d Artificial sweeteners and the neurobiology of sugar cravings: neuroscience 2010","volume":"83","author":"Yang","year":"2010","journal-title":"Yale J Biol Med"},{"key":"10.1093\/jn\/nxy021_bib30","doi-asserted-by":"crossref","DOI":"10.1016\/j.physbeh.2016.02.039","article-title":"The safety and regulatory process for low calorie sweeteners in the United States","volume":"164","author":"Roberts","year":"2016","journal-title":"Physiol Behav"},{"key":"10.1093\/jn\/nxy021_bib31","doi-asserted-by":"crossref","DOI":"10.1038\/ejcn.2014.19","article-title":"Non-nutritive sweeteners: no class effect on the glycaemic or appetite responses to ingested glucose","volume":"68","author":"Bryant","year":"2014","journal-title":"Eur J Clin Nutr"},{"key":"10.1093\/jn\/nxy021_bib32","doi-asserted-by":"crossref","DOI":"10.1038\/ijo.2014.109","article-title":"Nonnutritive sweeteners are not supernormal stimuli","volume":"39","author":"Antenucci","year":"2015","journal-title":"Int J Obes (Lond)"},{"key":"10.1093\/jn\/nxy021_bib33","doi-asserted-by":"crossref","DOI":"10.1016\/j.neuropharm.2007.09.009","article-title":"ASP decreases evoked extracellular dopamine levels in the rat brain: an in vivo voltammetry study","volume":"53","author":"Bergstrom","year":"2007","journal-title":"Neuropharmacology"},{"key":"10.1093\/jn\/nxy021_bib34","doi-asserted-by":"crossref","DOI":"10.1002\/syn.21519","article-title":"Sucrose-predictive cues evoke greater phasic dopamine release than saccharin-predictive cues","volume":"66","author":"McCutcheon","year":"2012","journal-title":"Synapse"},{"key":"10.1093\/jn\/nxy021_bib35","doi-asserted-by":"crossref","DOI":"10.1093\/ajcn\/65.3.737","article-title":"Cephalic phase responses to sweet taste","volume":"65","author":"Abdallah","year":"1997","journal-title":"Am J Clin Nutr"},{"key":"10.1093\/jn\/nxy021_bib36","doi-asserted-by":"crossref","DOI":"10.1055\/s-2007-978628","article-title":"Food-related sensory stimuli are able to promote pancreatic polypeptide elevation without evident cephalic phase insulin secretion in human obesity","volume":"32","author":"Morricone","year":"2000","journal-title":"Horm Metab Res"},{"key":"10.1093\/jn\/nxy021_bib37","doi-asserted-by":"crossref","DOI":"10.1016\/0031-9384(94)00373-D","article-title":"Sweet taste: effect on cephalic phase insulin release in men","volume":"57","author":"Teff","year":"1995","journal-title":"Physiol Behav"},{"key":"10.1093\/jn\/nxy021_bib38","doi-asserted-by":"crossref","DOI":"10.1016\/j.appet.2008.04.271","article-title":"Cephalic phase insulin release in healthy humans after taste stimulation?","volume":"51","author":"Just","year":"2008","journal-title":"Appetite"},{"key":"10.1093\/jn\/nxy021_bib39","article-title":"The effect of artificial sweetener on insulin secretion. 1. The effect of acesulfame K on insulin secretion in the rat (studies in vivo)","volume":"19","author":"Liang","year":"1987","journal-title":"Horm Metab Res"},{"key":"10.1093\/jn\/nxy021_bib40","doi-asserted-by":"crossref","DOI":"10.14712\/23362936.2014.11","article-title":"The role of taste in cephalic phase of insulin secretion","volume":"114","author":"Duskova","year":"2013","journal-title":"Prague Med Rep"},{"key":"10.1093\/jn\/nxy021_bib41","article-title":"The influence of sweetener solutions on the secretion of insulin and the blood glucose level","volume":"40","author":"Hartel","year":"1993","journal-title":"Ernahrungsumschau"},{"key":"10.1093\/jn\/nxy021_bib42","doi-asserted-by":"crossref","first-page":"194","DOI":"10.1016\/j.appet.2007.10.006","article-title":"Anticipatory physiological regulation in feeding biology: cephalic phase responses","volume":"50","author":"Power","year":"2008","journal-title":"Appetite"},{"key":"10.1093\/jn\/nxy021_bib43","doi-asserted-by":"crossref","first-page":"73","DOI":"10.1016\/j.metabol.2003.07.013","article-title":"Antihyperglycemic effects of stevioside in type 2 diabetic subjects","volume":"53","author":"Gregersen","year":"2004","journal-title":"Metabolism"},{"key":"10.1093\/jn\/nxy021_bib44","doi-asserted-by":"crossref","DOI":"10.1038\/ejcn.2014.208","article-title":"Sucralose enhances GLP-1 release and lowers blood glucose in the presence of carbohydrate in healthy subjects but not in patients with type 2 diabetes","volume":"69","author":"Temizkan","year":"2015","journal-title":"Eur J Clin Nutr"},{"key":"10.1093\/jn\/nxy021_bib45","doi-asserted-by":"crossref","DOI":"10.1016\/j.physbeh.2004.08.028","article-title":"Sweet and sour preferences in young children and adults: role of repeated exposure","volume":"83","author":"Liem","year":"2004","journal-title":"Physiol Behav"},{"key":"10.1093\/jn\/nxy021_bib46","doi-asserted-by":"crossref","DOI":"10.1016\/j.physbeh.2016.04.041","article-title":"Circuit organization of sugar reinforcement","volume":"164","author":"de Araujo","year":"2016","journal-title":"Physiol Behav"},{"key":"10.1093\/jn\/nxy021_bib47","doi-asserted-by":"crossref","DOI":"10.1016\/j.neuron.2008.01.032","article-title":"Food reward in the absence of taste receptor signaling","volume":"57","author":"de Araujo","year":"2008","journal-title":"Neuron"},{"key":"10.1093\/jn\/nxy021_bib48","doi-asserted-by":"crossref","first-page":"e81924","DOI":"10.1371\/journal.pone.0081924","article-title":"Effect of replacing sugar with non-caloric sweeteners in beverages on the reward value after repeated exposure","volume":"8","author":"Griffioen-Roose","year":"2013","journal-title":"PLoS One"},{"key":"10.1093\/jn\/nxy021_bib49","doi-asserted-by":"crossref","first-page":"53","DOI":"10.1016\/S0195-6663(80)80009-2","article-title":"Gustatory responses and eating duration of obese and lean adults","volume":"1","author":"Witherly","year":"1980","journal-title":"Appetite"},{"key":"10.1093\/jn\/nxy021_bib50","doi-asserted-by":"crossref","DOI":"10.1152\/ajpregu.00090.2009","article-title":"Sweetness and bitterness taste of meals per se does not mediate gastric emptying in humans","volume":"297","author":"Little","year":"2009","journal-title":"Am J Physiol Regul Integr Comp Physiol"},{"key":"10.1093\/jn\/nxy021_bib51","doi-asserted-by":"crossref","DOI":"10.1016\/0031-9384(88)90207-7","article-title":"Uncoupling sweet taste and calories: comparison of the effects of glucose and three intense sweeteners on hunger and food intake","volume":"43","author":"Rogers","year":"1988","journal-title":"Physiol Behav"},{"key":"10.1093\/jn\/nxy021_bib52","doi-asserted-by":"crossref","DOI":"10.1113\/jphysiol.2007.130906","article-title":"Sweet taste receptors in rat small intestine stimulate glucose absorption through apical GLUT2","volume":"582","author":"Mace","year":"2007","journal-title":"J Physiol"},{"key":"10.1093\/jn\/nxy021_bib53","doi-asserted-by":"crossref","DOI":"10.2337\/dc09-1185","article-title":"Ingestion of diet soda before a glucose load augments glucagon-like peptide-1 secretion","volume":"32","author":"Brown","year":"2009","journal-title":"Diabetes Care"},{"key":"10.1093\/jn\/nxy021_bib54","doi-asserted-by":"crossref","DOI":"10.1017\/S0007114510001327","article-title":"Effect of the artificial sweetener, sucralose, on small intestinal glucose absorption in healthy human subjects","volume":"104","author":"Ma","year":"2010","journal-title":"Br J Nutr"},{"key":"10.1093\/jn\/nxy021_bib55","doi-asserted-by":"crossref","first-page":"78","DOI":"10.3945\/ajcn.111.021543","article-title":"Effects of different sweet preloads on incretin hormone secretion, gastric emptying, and postprandial glycemia in healthy humans","volume":"95","author":"Wu","year":"2012","journal-title":"Am J Clin Nutr"},{"key":"10.1093\/jn\/nxy021_bib56","doi-asserted-by":"crossref","DOI":"10.1016\/j.jand.2013.07.045","article-title":"Effects of para-aminobenzoic acid (PABA) form and administration mode on PABA recovery in 24-hour urine collections","volume":"114","author":"Sharma","year":"2014","journal-title":"J Acad Nutr Diet"},{"key":"10.1093\/jn\/nxy021_bib57","doi-asserted-by":"crossref","first-page":"16","DOI":"10.1016\/j.nut.2007.09.001","article-title":"Sensitivity and specificity of published strategies using urinary creatinine to identify incomplete 24-h urine collection","volume":"24","author":"Murakami","year":"2008","journal-title":"Nutrition"},{"key":"10.1093\/jn\/nxy021_bib58","doi-asserted-by":"crossref","first-page":"629","DOI":"10.1080\/10408440701516184","article-title":"ASP: a safety evaluation based on current use levels, regulations, and toxicological and epidemiological studies","volume":"37","author":"Magnuson","year":"2007","journal-title":"Crit Rev Toxicol"},{"key":"10.1093\/jn\/nxy021_bib59","doi-asserted-by":"crossref","DOI":"10.2337\/diacare.19.9.1004","article-title":"Glycemic effect of a single high oral dose of the novel sweetener sucralose in patients with diabetes","volume":"19","author":"Mezitis","year":"1996","journal-title":"Diabetes Care"},{"key":"10.1093\/jn\/nxy021_bib60","doi-asserted-by":"crossref","DOI":"10.1016\/0031-9384(94)90021-3","article-title":"Intense sweeteners, food intake, and the weight of a body of evidence","volume":"55","author":"Renwick","year":"1994","journal-title":"Physiol Behav"},{"key":"10.1093\/jn\/nxy021_bib61","doi-asserted-by":"crossref","first-page":"78","DOI":"10.1124\/mi.8.2.5","article-title":"Taste cells of the gut and gastrointestinal chemosensation","volume":"8","author":"Egan","year":"2008","journal-title":"Mol Interv"},{"key":"10.1093\/jn\/nxy021_bib62","doi-asserted-by":"crossref","DOI":"10.1073\/pnas.0706890104","article-title":"Gut-expressed gustducin and taste receptors regulate secretion of glucagon-like peptide-1","volume":"104","author":"Jang","year":"2007","journal-title":"Proc Natl Acad Sci USA"},{"key":"10.1093\/jn\/nxy021_bib63","doi-asserted-by":"crossref","DOI":"10.1073\/pnas.0706678104","article-title":"T1R3 and gustducin in gut sense sugars to regulate expression of Na+-glucose cotransporter 1","volume":"104","author":"Margolskee","year":"2007","journal-title":"Proc Natl Acad Sci USA"},{"key":"10.1093\/jn\/nxy021_bib64","doi-asserted-by":"crossref","DOI":"10.1152\/ajpendo.90636.2008","article-title":"Incretin release from gut is acutely enhanced by sugar but not by sweeteners in vivo","volume":"296","author":"Fujita","year":"2009","journal-title":"Am J Physiol Endocrinol Metab"},{"key":"10.1093\/jn\/nxy021_bib65","doi-asserted-by":"crossref","DOI":"10.1017\/S000711451000512X","article-title":"Effects of carbohydrate sugars and artificial sweeteners on appetite and the secretion of gastrointestinal satiety peptides","volume":"105","author":"Steinert","year":"2011","journal-title":"Br J Nutr"},{"key":"10.1093\/jn\/nxy021_bib66","doi-asserted-by":"crossref","DOI":"10.2337\/dc12-2221","article-title":"Sucralose affects glycemic and hormonal responses to an oral glucose load","volume":"36","author":"Pepino","year":"2013","journal-title":"Diabetes Care"},{"key":"10.1093\/jn\/nxy021_bib67","doi-asserted-by":"crossref","DOI":"10.2337\/dc11-2424","article-title":"Effects of diet soda on gut hormones in youths with diabetes","volume":"35","author":"Brown","year":"2012","journal-title":"Diabetes Care"},{"key":"10.1093\/jn\/nxy021_bib68","doi-asserted-by":"crossref","DOI":"10.1038\/ijo.2016.225","article-title":"Effects of ASP-, monk fruit-, stevia- and sucrose-sweetened beverages on postprandial glucose, insulin and energy intake","volume":"41","author":"Tey","year":"2017","journal-title":"Int J Obes (Lond)"},{"key":"10.1093\/jn\/nxy021_bib69","doi-asserted-by":"crossref","DOI":"10.1016\/0031-9384(93)90139-7","article-title":"Consuming ASP with and without taste: differential effects on appetite and food intake of young adult males","volume":"53","author":"Black","year":"1993","journal-title":"Physiol Behav"},{"key":"10.1093\/jn\/nxy021_bib70","article-title":"Paradoxical effects of an intense sweetener (ASP) on appetite","volume":"1","author":"Blundell","year":"1986","journal-title":"Lancet"},{"key":"10.1093\/jn\/nxy021_bib71","doi-asserted-by":"crossref","DOI":"10.1016\/0031-9384(90)90126-O","article-title":"Oral stimulation with ASP increases hunger","volume":"47","author":"Tordoff","year":"1990","journal-title":"Physiol Behav"},{"key":"10.1093\/jn\/nxy021_bib72","doi-asserted-by":"crossref","DOI":"10.1016\/0031-9384(91)90321-E","article-title":"Soft drinks with ASP: effect on subjective hunger, food selection, and food intake of young adult males","volume":"49","author":"Black","year":"1991","journal-title":"Physiol Behav"},{"key":"10.1093\/jn\/nxy021_bib73","doi-asserted-by":"crossref","DOI":"10.1093\/ajcn\/53.5.1159","article-title":"Effects of consumption of caloric vs noncaloric sweet drinks on indices of hunger and food consumption in normal adults","volume":"53","author":"Canty","year":"1991","journal-title":"Am J Clin Nutr"},{"key":"10.1093\/jn\/nxy021_bib74","article-title":"Sweeteners and food intake: relevance to obesity","author":"Anderson","year":"1996","journal-title":"Progress in obesity research."},{"key":"10.1093\/jn\/nxy021_bib75","doi-asserted-by":"crossref","first-page":"691","DOI":"10.1038\/sj.ejcn.1602649","article-title":"Intense sweeteners, energy intake and the control of body weight","volume":"61","author":"Bellisle","year":"2007","journal-title":"Eur J Clin Nutr"},{"key":"10.1093\/jn\/nxy021_bib76","doi-asserted-by":"crossref","first-page":"63","DOI":"10.1079\/NRR200494","article-title":"Can artificial sweeteners help control body weight and prevent obesity?","volume":"18","author":"Benton","year":"2005","journal-title":"Nutr Res Rev"},{"key":"10.1093\/jn\/nxy021_bib77","article-title":"Overconsumption as a cause of weight gain: behavioural-physiological interactions in the control of food intake (appetite)","volume":"201","author":"Blundell","year":"1996","journal-title":"Ciba Found Symp"},{"key":"10.1093\/jn\/nxy021_bib78","doi-asserted-by":"crossref","DOI":"10.1111\/j.1467-3010.2006.00564.x","article-title":"A review of the effectiveness of ASP in helping with weight control","volume":"31","author":"de la Hunty","year":"2006","journal-title":"Nutr Bull"},{"key":"10.1093\/jn\/nxy021_bib79","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1111\/j.1753-4887.1995.tb01468.x","article-title":"Intense sweeteners and the control of appetite","volume":"53","author":"Drewnowski","year":"1995","journal-title":"Nutr Rev"},{"key":"10.1093\/jn\/nxy021_bib80","article-title":"Evaluation of the influence of intense sweeteners on the short-term control of appetite and caloric intake: a psychobiological approach","author":"Rogers","year":"1989","journal-title":"Progress in sweeteners"},{"key":"10.1093\/jn\/nxy021_bib81","doi-asserted-by":"crossref","DOI":"10.1093\/ajcn\/53.4.872","article-title":"Effects of intense sweeteners on hunger, food intake, and body weight: a review","volume":"53","author":"Rolls","year":"1991","journal-title":"Am J Clin Nutr"},{"key":"10.1093\/jn\/nxy021_bib82","doi-asserted-by":"crossref","first-page":"91","DOI":"10.1046\/j.1467-789X.2003.00102.x","article-title":"Effects of sugar intake on body weight: a review","volume":"4","author":"Vermunt","year":"2003","journal-title":"Obes Rev"},{"key":"10.1093\/jn\/nxy021_bib83","doi-asserted-by":"crossref","DOI":"10.1016\/0031-9384(91)90312-C","article-title":"Further analysis of the short-term inhibition of food intake in humans by the dipeptide L-aspartyl-L-phenylalanine methyl ester (ASP)","volume":"49","author":"Rogers","year":"1991","journal-title":"Physiol Behav"},{"key":"10.1093\/jn\/nxy021_bib84","doi-asserted-by":"crossref","DOI":"10.1016\/0031-9384(90)90377-G","article-title":"ASP ingested without tasting inhibits hunger and food intake","volume":"47","author":"Rogers","year":"1990","journal-title":"Physiol Behav"},{"key":"10.1093\/jn\/nxy021_bib85","doi-asserted-by":"crossref","DOI":"10.1093\/ajcn\/76.4.721","article-title":"Sucrose compared with artificial sweeteners: different effects on ad libitum food intake and body weight after 10 wk of supplementation in overweight subjects","volume":"76","author":"Raben","year":"2002","journal-title":"Am J Clin Nutr"},{"key":"10.1093\/jn\/nxy021_bib86","doi-asserted-by":"crossref","DOI":"10.1503\/cmaj.161390","article-title":"Nonnutritive sweeteners and cardiometabolic health: a systematic review and meta-analysis of randomized controlled trials and prospective cohort studies","volume":"189","author":"Azad","year":"2017","journal-title":"CMAJ"},{"key":"10.1093\/jn\/nxy021_bib87","doi-asserted-by":"crossref","DOI":"10.1016\/j.jand.2015.01.006","article-title":"Substitution of sugar-sweetened beverages with other beverage alternatives: a review of long-term health outcomes","volume":"115","author":"Zheng","year":"2015","journal-title":"J Acad Nutr Diet"}],"container-title":["The Journal of Nutrition"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0022316622108151?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0022316622108151?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/academic.oup.com\/jn\/article-pdf\/148\/4\/650\/24583892\/nxy021.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,6,13]],"date-time":"2023-06-13T23:42:46Z","timestamp":1686699766000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0022316622108151"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,4]]},"references-count":87,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2018,4]]}},"alternative-id":["S0022316622108151"],"URL":"https:\/\/doi.org\/10.1093\/jn\/nxy021","relation":{},"ISSN":["0022-3166"],"issn-type":[{"value":"0022-3166","type":"print"}],"subject":[],"published":{"date-parts":[[2018,4]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Aspartame Consumption for 12 Weeks Does Not Affect Glycemia, Appetite, or Body Weight of Healthy, Lean Adults in a Randomized Controlled Trial","name":"articletitle","label":"Article Title"},{"value":"The Journal of Nutrition","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1093\/jn\/nxy021","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2018 American Society for Nutrition. Published by Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}]}}