{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,30]],"date-time":"2026-10-30T08:33:51Z","timestamp":1793349231598,"version":"4.5.0"},"reference-count":0,"publisher":"Oxford University Press (OUP)","issue":"3","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[1966,9,1]]},"abstract":"<jats:title>Summary<\/jats:title>\n                  <jats:p>In a series of 10 independent experiments, performed on 314 adult and 105 newborn BALB\/c mice, preinoculation with lymphocytic choriomeningitis (LCM) virus induced a significant protection against the leukemic disease due to infection with Rauscher virus. This protection was evidenced by lower incidence of leukemia, marked prolongation of incubation period, and delayed mortality. A significant proportion of LCM-pretreated animals remained free of leukemia symptoms for their lifespan. The protection was effective in adult mice when LCM virus was inoculated 1 to 5 days before Rauscher virus, being most effective when done 1 or 2 days in advance. In newborn mice the shielding effect of LCM infection persisted longer. It is concluded that concomitant infection with LCM and Rauscher viruses represents a working model demonstrating an efficient and sparing interference by a nonlethal and even asymptomatic viral infection with the development of usually fatal malignancy induced by an oncogenic virus.<\/jats:p>","DOI":"10.1093\/jnci\/37.3.381","type":"journal-article","created":{"date-parts":[[2017,2,2]],"date-time":"2017-02-02T17:04:48Z","timestamp":1486055088000},"page":"381-388","source":"Crossref","is-referenced-by-count":15,"title":["Interference Between Lymphocytic Choriomeningitis and Rauscher Leukemia in Mice"],"prefix":"10.1093","volume":"37","author":[{"given":"Jung Koo","family":"Youn","sequence":"first","affiliation":[{"name":"Tissue Culture and Virus Laboratory, Institut Gustave-Roussy , 94 Villejuif and C.N.R.S., France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Georges","family":"Barski","sequence":"additional","affiliation":[{"name":"Tissue Culture and Virus Laboratory, Institut Gustave-Roussy , 94 Villejuif and C.N.R.S., France"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[1966,9,1]]},"container-title":["JNCI: Journal of the National Cancer Institute"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/academic.oup.com\/jnci\/article-pdf\/37\/3\/381\/72611581\/jnci_37_3_381.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/academic.oup.com\/jnci\/article-pdf\/37\/3\/381\/72611581\/jnci_37_3_381.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,10,30]],"date-time":"2026-10-30T08:07:29Z","timestamp":1793347649000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/jnci\/article\/37\/3\/381\/1016338"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1966,9,1]]},"references-count":0,"journal-issue":{"issue":"3","published-online":{"date-parts":[[1966,9,1]]},"published-print":{"date-parts":[[1966,9,1]]}},"URL":"https:\/\/doi.org\/10.1093\/jnci\/37.3.381","relation":{},"ISSN":["0027-8874","1460-2105"],"issn-type":[{"value":"0027-8874","type":"print"},{"value":"1460-2105","type":"electronic"}],"subject":[],"published-other":{"date-parts":[[1966,9]]},"published":{"date-parts":[[1966,9,1]]}}}