{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,17]],"date-time":"2026-07-17T14:27:02Z","timestamp":1784298422331,"version":"3.55.0"},"reference-count":39,"publisher":"Oxford University Press (OUP)","issue":"21","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["JNCI Journal of the National Cancer Institute"],"published-print":{"date-parts":[[1999,11,3]]},"DOI":"10.1093\/jnci\/91.21.1847","type":"journal-article","created":{"date-parts":[[2002,7,26]],"date-time":"2002-07-26T22:35:58Z","timestamp":1027722958000},"page":"1847-1856","source":"Crossref","is-referenced-by-count":326,"title":["Randomized Trial of Fenretinide to Prevent Second Breast Malignancy in Women With Early Breast Cancer"],"prefix":"10.1093","volume":"91","author":[{"given":"U.","family":"Veronesi","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"G.","family":"De Palo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"E.","family":"Marubini","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"A.","family":"Costa","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"F.","family":"Formelli","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"L.","family":"Mariani","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"A.","family":"Decensi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"T.","family":"Camerini","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M. R.","family":"Del Turco","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M. G.","family":"Di Mauro","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M. G.","family":"Muraca","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M.","family":"Del Vecchio","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"C.","family":"Pinto","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"G.","family":"D'Aiuto","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"C.","family":"Boni","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"T.","family":"Campa","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"A.","family":"Magni","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"R.","family":"Miceli","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M.","family":"Perloff","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"W. F.","family":"Malone","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M. B.","family":"Sporn","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","reference":[{"issue":"23_Part_1","key":"1_23139971","first-page":"6215","volume":"51","author":"Sporn","year":"1991","journal-title":"Cancer Research","ISSN":"https:\/\/id.crossref.org\/issn\/0008-5472","issn-type":"print"},{"issue":"2","key":"2_15654483","doi-asserted-by":"publisher","first-page":"193","DOI":"10.1016\/0092-8674(94)90189-9","volume":"79","author":"Gibbs","year":"1994","journal-title":"Cell","ISSN":"https:\/\/id.crossref.org\/issn\/0092-8674","issn-type":"print"},{"issue":"4","key":"3_15828967","doi-asserted-by":"crossref","first-page":"801","DOI":"10.1200\/JCO.1995.13.4.801","volume":"13","author":"Schipper","year":"1995","journal-title":"Journal of Clinical Oncology","ISSN":"https:\/\/id.crossref.org\/issn\/0732-183X","issn-type":"print"},{"issue":"5340","key":"4_5784044","doi-asserted-by":"publisher","first-page":"1073","DOI":"10.1126\/science.278.5340.1073","volume":"278","author":"Hong","year":"1997","journal-title":"Science","ISSN":"https:\/\/id.crossref.org\/issn\/0036-8075","issn-type":"print"},{"issue":"20","key":"5_6202593","doi-asserted-by":"publisher","first-page":"1514","DOI":"10.1093\/jnci\/90.20.1514","volume":"90","author":"Lippman","year":"1998","journal-title":"JNCI Journal of the National Cancer Institute","ISSN":"https:\/\/id.crossref.org\/issn\/0027-8874","issn-type":"print"},{"issue":"7","key":"6_9772178","first-page":"1651","volume":"52","author":"Boone","year":"1992","journal-title":"Cancer Research","ISSN":"https:\/\/id.crossref.org\/issn\/0008-5472","issn-type":"print"},{"issue":"18","key":"7_6158691","doi-asserted-by":"publisher","first-page":"1371","DOI":"10.1093\/jnci\/90.18.1371","volume":"90","author":"Fisher","year":"1998","journal-title":"JNCI Journal of the National Cancer Institute","ISSN":"https:\/\/id.crossref.org\/issn\/0027-8874","issn-type":"print"},{"issue":"4","key":"8_4746131","first-page":"1339","volume":"39","author":"Moon","year":"1979","journal-title":"Cancer Research","ISSN":"https:\/\/id.crossref.org\/issn\/0008-5472","issn-type":"print"},{"issue":"10","key":"10_14472507","doi-asserted-by":"crossref","first-page":"2036","DOI":"10.1200\/JCO.1993.11.10.2036","volume":"11","author":"Formelli","year":"1993","journal-title":"Journal of Clinical Oncology","ISSN":"https:\/\/id.crossref.org\/issn\/0732-183X","issn-type":"print"},{"issue":"22","key":"11_16064228","doi-asserted-by":"publisher","first-page":"1655","DOI":"10.1093\/jnci\/87.22.1655","volume":"87","author":"Lotan","year":"1995","journal-title":"JNCI Journal of the National Cancer Institute","ISSN":"https:\/\/id.crossref.org\/issn\/0027-8874","issn-type":"print"},{"issue":"37","key":"12_16393451","doi-asserted-by":"publisher","first-page":"22441","DOI":"10.1074\/jbc.271.37.22441","volume":"271","author":"Delia","year":"1996","journal-title":"Journal of Biological Chemistry","ISSN":"https:\/\/id.crossref.org\/issn\/0021-9258","issn-type":"print"},{"issue":"5","key":"13_9806150","doi-asserted-by":"crossref","first-page":"839","DOI":"10.1200\/JCO.1992.10.5.839","volume":"10","author":"Smith","year":"1992","journal-title":"Journal of Clinical Oncology","ISSN":"https:\/\/id.crossref.org\/issn\/0732-183X","issn-type":"print"},{"issue":"7","key":"15_15930796","doi-asserted-by":"publisher","first-page":"1578","DOI":"10.1200\/JCO.2005.03.115","volume":"13","author":"Broet","year":"1995","journal-title":"Journal of Clinical Oncology","ISSN":"https:\/\/id.crossref.org\/issn\/0732-183X","issn-type":"print"},{"issue":"8785","key":"17_9676435","doi-asserted-by":"crossref","first-page":"71","DOI":"10.1016\/0140-6736(92)90997-H","volume":"339","year":"1992","journal-title":"Lancet","ISSN":"https:\/\/id.crossref.org\/issn\/0140-6736","issn-type":"print"},{"issue":"8","key":"18_5138372","doi-asserted-by":"crossref","first-page":"479","DOI":"10.1056\/NEJM198902233200802","volume":"320","author":"Fisher","year":"1989","journal-title":"New England Journal of Medicine","ISSN":"https:\/\/id.crossref.org\/issn\/0028-4793","issn-type":"print"},{"issue":"6","key":"19_5942960","doi-asserted-by":"crossref","first-page":"884","DOI":"10.1177\/030089169708300603","volume":"83","author":"De Palo","year":"1997","journal-title":"Tumori","ISSN":"https:\/\/id.crossref.org\/issn\/0300-8916","issn-type":"print"},{"issue":"21","key":"21_5396063","first-page":"6149","volume":"49","author":"Formelli","year":"1989","journal-title":"Cancer Research","ISSN":"https:\/\/id.crossref.org\/issn\/0008-5472","issn-type":"print"},{"issue":"5","key":"22_5293631","doi-asserted-by":"publisher","first-page":"805","DOI":"10.1016\/0277-5379(89)90124-7","volume":"25","author":"Costa","year":"1989","journal-title":"European journal of cancer &amp; clinical oncology","ISSN":"https:\/\/id.crossref.org\/issn\/0277-5379","issn-type":"print"},{"issue":"2","key":"23_14663668","doi-asserted-by":"publisher","first-page":"105","DOI":"10.1093\/jnci\/86.2.105","volume":"86","author":"Decensi","year":"1994","journal-title":"JNCI Journal of the National Cancer Institute","ISSN":"https:\/\/id.crossref.org\/issn\/0027-8874","issn-type":"print"},{"issue":"2","key":"25_8440666","doi-asserted-by":"publisher","first-page":"111","DOI":"10.1016\/0197-2456(80)90014-8","volume":"1","author":"Wu","year":"1980","journal-title":"Controlled clinical trials","ISSN":"https:\/\/id.crossref.org\/issn\/0197-2456","issn-type":"print"},{"issue":"2","key":"26_16854981","doi-asserted-by":"publisher","first-page":"167","DOI":"10.1023\/A:1005765403093","volume":"44","author":"Mariani","year":"1997","journal-title":"Breast cancer research and treatment","ISSN":"https:\/\/id.crossref.org\/issn\/0167-6806","issn-type":"print"},{"issue":"20","key":"27_14463579","first-page":"4769","volume":"53","author":"Torrisi","year":"1993","journal-title":"Cancer Research","ISSN":"https:\/\/id.crossref.org\/issn\/0008-5472","issn-type":"print"},{"issue":"6","key":"28_6040540","doi-asserted-by":"publisher","first-page":"787","DOI":"10.1002\/(SICI)1097-0215(19980610)76:6<787::AID-IJC3>3.0.CO;2-U","volume":"76","author":"Torrisi","year":"1998","journal-title":"International journal of cancer. Journal international du cancer","ISSN":"https:\/\/id.crossref.org\/issn\/0020-7136","issn-type":"print"},{"issue":"9113","key":"29_6006613","doi-asserted-by":"publisher","first-page":"1393","DOI":"10.1016\/S0140-6736(97)10384-1","volume":"351","author":"Hankinson","year":"1998","journal-title":"Lancet","ISSN":"https:\/\/id.crossref.org\/issn\/0140-6736","issn-type":"print"},{"issue":"1","key":"30_21360864","doi-asserted-by":"publisher","first-page":"239","DOI":"10.1093\/biomet\/69.1.239","volume":"69","author":"SCHOENFELD","year":"1982","journal-title":"Biometrika","ISSN":"https:\/\/id.crossref.org\/issn\/0006-3444","issn-type":"print"},{"issue":"2","key":"31_13585424","doi-asserted-by":"publisher","first-page":"361","DOI":"10.2307\/2530862","volume":"41","author":"Gail","year":"1985","journal-title":"Biometrics","ISSN":"https:\/\/id.crossref.org\/issn\/0006-341X","issn-type":"print"},{"issue":"5","key":"32_5270838","doi-asserted-by":"crossref","first-page":"551","DOI":"10.1002\/sim.4780080504","volume":"8","author":"Durrleman","year":"1989","journal-title":"Statistics in medicine","ISSN":"https:\/\/id.crossref.org\/issn\/0277-6715","issn-type":"print"},{"issue":"2","key":"37_15829265","doi-asserted-by":"publisher","first-page":"146","DOI":"10.1093\/jnci\/87.2.146","volume":"87","author":"DE PALO","year":"1995","journal-title":"JNCI Journal of the National Cancer Institute","ISSN":"https:\/\/id.crossref.org\/issn\/0027-8874","issn-type":"print"},{"issue":"11_Part_2","key":"39_23090976","first-page":"3351","volume":"35","author":"de Waard","year":"1975","journal-title":"Cancer Research","ISSN":"https:\/\/id.crossref.org\/issn\/0008-5472","issn-type":"print"},{"issue":"6","key":"40_5463601","doi-asserted-by":"crossref","first-page":"1133","DOI":"10.1093\/oxfordjournals.aje.a115440","volume":"130","author":"SWANSON","year":"1989","journal-title":"American Journal of Epidemiology","ISSN":"https:\/\/id.crossref.org\/issn\/0002-9262","issn-type":"print"},{"issue":"20","key":"41_5433324","doi-asserted-by":"publisher","first-page":"2853","DOI":"10.1001\/jama.1989.03430200097033","volume":"262","author":"London","year":"1989","journal-title":"JAMA","ISSN":"https:\/\/id.crossref.org\/issn\/0098-7484","issn-type":"print"},{"issue":"1","key":"42_16000116","doi-asserted-by":"publisher","first-page":"19","DOI":"10.1093\/jnci\/87.1.19","volume":"87","author":"Veronesi","year":"1995","journal-title":"JNCI Journal of the National Cancer Institute","ISSN":"https:\/\/id.crossref.org\/issn\/0027-8874","issn-type":"print"},{"issue":"19","key":"43_5760745","first-page":"4158","volume":"57","author":"Widschwendter","year":"1997","journal-title":"Cancer Research","ISSN":"https:\/\/id.crossref.org\/issn\/0008-5472","issn-type":"print"},{"issue":"5","key":"44_16604714","doi-asserted-by":"crossref","first-page":"444","DOI":"10.1177\/030089169608200506","volume":"82","author":"Mariani","year":"1996","journal-title":"Tumori","ISSN":"https:\/\/id.crossref.org\/issn\/0300-8916","issn-type":"print"},{"issue":"16","key":"46_5307496","first-page":"4472","volume":"49","author":"Ratko","year":"1989","journal-title":"Cancer Research","ISSN":"https:\/\/id.crossref.org\/issn\/0008-5472","issn-type":"print"},{"issue":"7","key":"47_16052374","first-page":"863","volume":"6","author":"Pellegrini","year":"1995","journal-title":"Cell Growth &amp; Differentiation","ISSN":"https:\/\/id.crossref.org\/issn\/1044-9523","issn-type":"print"},{"issue":"5182","key":"48_15638334","doi-asserted-by":"publisher","first-page":"66","DOI":"10.1126\/science.7545954","volume":"266","author":"Miki","year":"1994","journal-title":"Science","ISSN":"https:\/\/id.crossref.org\/issn\/0036-8075","issn-type":"print"},{"issue":"20","key":"49_16018837","first-page":"4561","volume":"55","author":"Gudas","year":"1995","journal-title":"Cancer Research","ISSN":"https:\/\/id.crossref.org\/issn\/0008-5472","issn-type":"print"},{"key":"50_23957220","doi-asserted-by":"crossref","first-page":"862","DOI":"10.1093\/jnci\/90.11.862a","volume":"90","year":"1998","journal-title":"JNCI Journal of the National Cancer Institute","ISSN":"https:\/\/id.crossref.org\/issn\/0027-8874","issn-type":"print"}],"container-title":["JNCI Journal of the National Cancer Institute"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/academic.oup.com\/jnci\/article-pdf\/91\/21\/1847\/8119009\/1847.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2017,12,7]],"date-time":"2017-12-07T18:33:58Z","timestamp":1512671638000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/jnci\/article-lookup\/doi\/10.1093\/jnci\/91.21.1847"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1999,11,3]]},"references-count":39,"journal-issue":{"issue":"21","published-print":{"date-parts":[[1999,11,3]]}},"URL":"https:\/\/doi.org\/10.1093\/jnci\/91.21.1847","relation":{},"ISSN":["0027-8874","1460-2105"],"issn-type":[{"value":"0027-8874","type":"print"},{"value":"1460-2105","type":"electronic"}],"subject":[],"published":{"date-parts":[[1999,11,3]]}}}