{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,25]],"date-time":"2026-09-25T20:46:41Z","timestamp":1790369201439,"version":"4.1.0"},"reference-count":70,"publisher":"Oxford University Press (OUP)","issue":"12","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["JNCI Journal of the National Cancer Institute"],"published-print":{"date-parts":[[2003,6,18]]},"DOI":"10.1093\/jnci\/95.12.896","type":"journal-article","created":{"date-parts":[[2003,6,17]],"date-time":"2003-06-17T20:29:40Z","timestamp":1055881780000},"page":"896-905","source":"Crossref","is-referenced-by-count":101,"title":["Vitamin D2 Analog 19-nor-1,25-Dihydroxyvitamin D2: Antitumor Activity Against Leukemia, Myeloma, and Colon Cancer Cells"],"prefix":"10.1093","volume":"95","author":[{"given":"T.","family":"Kumagai","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J.","family":"O'Kelly","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J. W.","family":"Said","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"H. P.","family":"Koeffler","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","reference":[{"issue":"12","key":"1_13689520","first-page":"1399","volume":"69","author":"Koeffler","year":"1985","journal-title":"Cancer treatment reports","ISSN":"https:\/\/id.crossref.org\/issn\/0361-5960","issn-type":"print"},{"issue":"11","key":"2_13743008","first-page":"1339","volume":"69","author":"Staquet","year":"1985","journal-title":"Cancer treatment reports","ISSN":"https:\/\/id.crossref.org\/issn\/0361-5960","issn-type":"print"},{"issue":"12_Part_1","key":"3_23144452","first-page":"5624","volume":"44","author":"Koeffler","year":"1984","journal-title":"Cancer Research","ISSN":"https:\/\/id.crossref.org\/issn\/0008-5472","issn-type":"print"},{"issue":"2","key":"4_9519692","doi-asserted-by":"publisher","first-page":"832","DOI":"10.1210\/endo-129-2-832","volume":"129","author":"ABE","year":"1991","journal-title":"Endocrinology","ISSN":"https:\/\/id.crossref.org\/issn\/0013-7227","issn-type":"print"},{"issue":"1","key":"5_21319225","doi-asserted-by":"crossref","first-page":"75","DOI":"10.1182\/blood.V78.1.75.75","volume":"78","author":"Zhou","year":"1991","journal-title":"Blood","ISSN":"https:\/\/id.crossref.org\/issn\/0006-4971","issn-type":"print"},{"issue":"6","key":"6_15515479","doi-asserted-by":"publisher","first-page":"453","DOI":"10.1016\/0145-2126(94)90081-7","volume":"18","author":"Jung","year":"1994","journal-title":"Leukemia research","ISSN":"https:\/\/id.crossref.org\/issn\/0145-2126","issn-type":"print"},{"issue":"7","key":"7_14698434","first-page":"1653","volume":"54","author":"Anzano","year":"1994","journal-title":"Cancer Research","ISSN":"https:\/\/id.crossref.org\/issn\/0008-5472","issn-type":"print"},{"issue":"1","key":"8_15747799","doi-asserted-by":"publisher","first-page":"65","DOI":"10.1016\/0145-2126(94)00065-I","volume":"19","author":"Pakkala","year":"1995","journal-title":"Leukemia research","ISSN":"https:\/\/id.crossref.org\/issn\/0145-2126","issn-type":"print"},{"issue":"20","key":"9_5789399","first-page":"4545","volume":"57","author":"Koike","year":"1997","journal-title":"Cancer Research","ISSN":"https:\/\/id.crossref.org\/issn\/0008-5472","issn-type":"print"},{"issue":"15","key":"10_6110882","first-page":"3370","volume":"58","author":"Kubota","year":"1998","journal-title":"Cancer Research","ISSN":"https:\/\/id.crossref.org\/issn\/0008-5472","issn-type":"print"},{"issue":"16","key":"11_10940330","first-page":"4023","volume":"59","author":"Hisatake","year":"1999","journal-title":"Cancer Research","ISSN":"https:\/\/id.crossref.org\/issn\/0008-5472","issn-type":"print"},{"issue":"8","key":"12_21330402","doi-asserted-by":"publisher","first-page":"2427","DOI":"10.1182\/blood.V97.8.2427","volume":"97","author":"Hisatake","year":"2001","journal-title":"Blood","ISSN":"https:\/\/id.crossref.org\/issn\/0006-4971","issn-type":"print"},{"issue":"2 Suppl 2","key":"13_6219979","doi-asserted-by":"crossref","first-page":"S48","DOI":"10.1053\/ajkd.1998.v32.pm9808143","volume":"32","author":"Llach","year":"1998","journal-title":"American journal of kidney diseases : the official journal of the National Kidney Foundation","ISSN":"https:\/\/id.crossref.org\/issn\/0272-6386","issn-type":"print"},{"issue":"8","key":"14_6108812","doi-asserted-by":"crossref","first-page":"1427","DOI":"10.1681\/ASN.V981427","volume":"9","author":"Martin","year":"1998","journal-title":"Journal of the American Society of Nephrology","ISSN":"https:\/\/id.crossref.org\/issn\/1046-6673","issn-type":"print"},{"issue":"3","key":"15_6530225","first-page":"901","volume":"6","author":"Chen","year":"2000","journal-title":"Clinical Cancer Research","ISSN":"https:\/\/id.crossref.org\/issn\/1078-0432","issn-type":"print"},{"issue":"8","key":"16_17008944","doi-asserted-by":"publisher","first-page":"1091","DOI":"10.1172\/JCI200212392","volume":"109","author":"O'Kelly","year":"2002","journal-title":"Journal of Clinical Investigation","ISSN":"https:\/\/id.crossref.org\/issn\/0021-9738","issn-type":"print"},{"issue":"9","key":"17_11294555","doi-asserted-by":"crossref","first-page":"897","DOI":"10.1080\/00365520121464","volume":"36","author":"van Rees","year":"2001","journal-title":"Scandinavian journal of gastroenterology","ISSN":"https:\/\/id.crossref.org\/issn\/0036-5521","issn-type":"print"},{"issue":"3","key":"18_16902554","first-page":"632","volume":"62","author":"Ristimaki","year":"2002","journal-title":"Cancer Research","ISSN":"https:\/\/id.crossref.org\/issn\/0008-5472","issn-type":"print"},{"issue":"4","key":"19_6202623","doi-asserted-by":"crossref","first-page":"1193","DOI":"10.1152\/physrev.1998.78.4.1193","volume":"78","author":"JONES","year":"1998","journal-title":"Physiological Reviews","ISSN":"https:\/\/id.crossref.org\/issn\/0031-9333","issn-type":"print"},{"issue":"3","key":"20_14673504","doi-asserted-by":"publisher","first-page":"900","DOI":"10.1073\/pnas.91.3.900","volume":"91","author":"Zierold","year":"1994","journal-title":"PNAS","ISSN":"https:\/\/id.crossref.org\/issn\/0027-8424","issn-type":"print"},{"issue":"14","key":"21_14704242","doi-asserted-by":"crossref","first-page":"10545","DOI":"10.1016\/S0021-9258(17)34094-2","volume":"269","author":"Ohyama","year":"1994","journal-title":"Journal of Biological Chemistry","ISSN":"https:\/\/id.crossref.org\/issn\/0021-9258","issn-type":"print"},{"issue":"2","key":"22_16144967","first-page":"264","volume":"56","author":"Wang","year":"1996","journal-title":"Cancer Research","ISSN":"https:\/\/id.crossref.org\/issn\/0008-5472","issn-type":"print"},{"issue":"6","key":"23_21324947","doi-asserted-by":"crossref","first-page":"2201","DOI":"10.1182\/blood.V88.6.2201.bloodjournal8862201","volume":"88","author":"Munker","year":"1996","journal-title":"Blood","ISSN":"https:\/\/id.crossref.org\/issn\/0006-4971","issn-type":"print"},{"issue":"11","key":"24_15635229","first-page":"3397","volume":"9","author":"Jiang","year":"1994","journal-title":"Oncogene","ISSN":"https:\/\/id.crossref.org\/issn\/0950-9232","issn-type":"print"},{"issue":"3","key":"25_16370909","doi-asserted-by":"publisher","first-page":"248","DOI":"10.1002\/(SICI)1096-9896(199607)179:3<248::AID-PATH571>3.0.CO;2-6","volume":"179","author":"Doglioni","year":"1996","journal-title":"The Journal of pathology","ISSN":"https:\/\/id.crossref.org\/issn\/0022-3417","issn-type":"print"},{"issue":"10","key":"26_16083026","doi-asserted-by":"publisher","first-page":"1052","DOI":"10.1038\/nm1095-1052","volume":"1","author":"Yang","year":"1995","journal-title":"Nature medicine","ISSN":"https:\/\/id.crossref.org\/issn\/1078-8956","issn-type":"print"},{"issue":"2","key":"27_10978988","doi-asserted-by":"publisher","first-page":"226","DOI":"10.1002\/(SICI)1097-4644(19991101)75:2<226::AID-JCB5>3.0.CO;2-L","volume":"75","author":"Harrison","year":"1999","journal-title":"Journal of cellular biochemistry","ISSN":"https:\/\/id.crossref.org\/issn\/0730-2312","issn-type":"print"},{"issue":"8","key":"28_10784267","doi-asserted-by":"publisher","first-page":"4240","DOI":"10.1073\/pnas.96.8.4240","volume":"96","author":"Cantley","year":"1999","journal-title":"PNAS","ISSN":"https:\/\/id.crossref.org\/issn\/0027-8424","issn-type":"print"},{"issue":"4","key":"29_6485173","doi-asserted-by":"publisher","first-page":"387","DOI":"10.1016\/S0092-8674(00)80674-1","volume":"100","author":"Di Cristofano","year":"2000","journal-title":"Cell","ISSN":"https:\/\/id.crossref.org\/issn\/0092-8674","issn-type":"print"},{"issue":"5308","key":"30_16723028","doi-asserted-by":"publisher","first-page":"1943","DOI":"10.1126\/science.275.5308.1943","volume":"275","author":"Li","year":"1997","journal-title":"Science","ISSN":"https:\/\/id.crossref.org\/issn\/0036-8075","issn-type":"print"},{"issue":"23","key":"31_5818179","first-page":"5221","volume":"57","author":"Teng","year":"1997","journal-title":"Cancer Research","ISSN":"https:\/\/id.crossref.org\/issn\/0008-5472","issn-type":"print"},{"issue":"10","key":"32_6018571","first-page":"2095","volume":"58","author":"Obata","year":"1998","journal-title":"Cancer Research","ISSN":"https:\/\/id.crossref.org\/issn\/0008-5472","issn-type":"print"},{"issue":"9","key":"33_21327530","doi-asserted-by":"crossref","first-page":"3410","DOI":"10.1182\/blood.V92.9.3410","volume":"92","author":"Sakai","year":"1998","journal-title":"Blood","ISSN":"https:\/\/id.crossref.org\/issn\/0006-4971","issn-type":"print"},{"issue":"13","key":"34_6073102","first-page":"2720","volume":"58","author":"Vlietstra","year":"1998","journal-title":"Cancer Research","ISSN":"https:\/\/id.crossref.org\/issn\/0008-5472","issn-type":"print"},{"issue":"2","key":"35_10722232","doi-asserted-by":"publisher","first-page":"185","DOI":"10.1093\/hmg\/8.2.185","volume":"8","author":"Dahia","year":"1999","journal-title":"Human Molecular Genetics","ISSN":"https:\/\/id.crossref.org\/issn\/0964-6906","issn-type":"print"},{"issue":"4","key":"36_6499717","doi-asserted-by":"publisher","first-page":"170","DOI":"10.1002\/(SICI)1096-8652(200004)63:4<170::AID-AJH2>3.0.CO;2-0","volume":"63","author":"Liu","year":"2000","journal-title":"American journal of hematology","ISSN":"https:\/\/id.crossref.org\/issn\/0361-8609","issn-type":"print"},{"issue":"4","key":"37_6108842","doi-asserted-by":"publisher","first-page":"348","DOI":"10.1038\/1235","volume":"19","author":"Di Cristofano","year":"1998","journal-title":"Nature genetics","ISSN":"https:\/\/id.crossref.org\/issn\/1061-4036","issn-type":"print"},{"issue":"21","key":"38_6215063","doi-asserted-by":"publisher","first-page":"1169","DOI":"10.1016\/S0960-9822(07)00488-5","volume":"8","author":"Suzuki","year":"1998","journal-title":"Current biology : CB","ISSN":"https:\/\/id.crossref.org\/issn\/0960-9822","issn-type":"print"},{"issue":"2","key":"39_10452130","doi-asserted-by":"publisher","first-page":"109","DOI":"10.1034\/j.1600-0609.2000.90181.x","volume":"65","author":"Aggerholm","year":"2000","journal-title":"European journal of haematology","ISSN":"https:\/\/id.crossref.org\/issn\/0902-4441","issn-type":"print"},{"issue":"1","key":"40_15737834","doi-asserted-by":"publisher","first-page":"20","DOI":"10.1210\/en.136.1.20","volume":"136","author":"Skowronski","year":"1995","journal-title":"Endocrinology","ISSN":"https:\/\/id.crossref.org\/issn\/0013-7227","issn-type":"print"},{"issue":"13","key":"41_15528044","first-page":"3413","volume":"54","author":"Danielpour","year":"1994","journal-title":"Cancer Research","ISSN":"https:\/\/id.crossref.org\/issn\/0008-5472","issn-type":"print"},{"issue":"3","key":"42_16877546","doi-asserted-by":"publisher","first-page":"413","DOI":"10.1002\/(SICI)1097-4644(19970901)66:3<413::AID-JCB13>3.0.CO;2-F","volume":"66","author":"Campbell","year":"1997","journal-title":"Journal of cellular biochemistry","ISSN":"https:\/\/id.crossref.org\/issn\/0730-2312","issn-type":"print"},{"issue":"2","key":"43_6411447","doi-asserted-by":"publisher","first-page":"283","DOI":"10.1093\/hmg\/9.2.283","volume":"9","author":"Guanti","year":"2000","journal-title":"Human Molecular Genetics","ISSN":"https:\/\/id.crossref.org\/issn\/0964-6906","issn-type":"print"},{"issue":"18","key":"44_5742859","first-page":"3935","volume":"57","author":"Tashiro","year":"1997","journal-title":"Cancer Research","ISSN":"https:\/\/id.crossref.org\/issn\/0008-5472","issn-type":"print"},{"issue":"5","key":"45_16118482","doi-asserted-by":"publisher","first-page":"619","DOI":"10.1016\/0955-0674(95)80102-2","volume":"7","author":"Takeichi","year":"1995","journal-title":"Current opinion in cell biology","ISSN":"https:\/\/id.crossref.org\/issn\/0955-0674","issn-type":"print"},{"issue":"3","key":"46_16198043","doi-asserted-by":"publisher","first-page":"345","DOI":"10.1016\/S0092-8674(00)81279-9","volume":"84","author":"Gumbiner","year":"1996","journal-title":"Cell","ISSN":"https:\/\/id.crossref.org\/issn\/0092-8674","issn-type":"print"},{"issue":"6672","key":"47_5932545","doi-asserted-by":"publisher","first-page":"190","DOI":"10.1038\/32433","volume":"392","author":"Perl","year":"1998","journal-title":"Nature; Physical Science (London)","ISSN":"https:\/\/id.crossref.org\/issn\/1476-4687","issn-type":"print"},{"issue":"2","key":"48_10768441","doi-asserted-by":"publisher","first-page":"73","DOI":"10.1016\/S0968-0004(98)01343-7","volume":"24","author":"Christofori","year":"1999","journal-title":"Trends in biochemical sciences","ISSN":"https:\/\/id.crossref.org\/issn\/0167-7640","issn-type":"print"},{"issue":"14","key":"49_15549643","first-page":"3929","volume":"54","author":"Umbas","year":"1994","journal-title":"Cancer Research","ISSN":"https:\/\/id.crossref.org\/issn\/0008-5472","issn-type":"print"},{"issue":"2","key":"50_15751181","doi-asserted-by":"crossref","first-page":"376","DOI":"10.1038\/bjc.1995.76","volume":"71","author":"Katagiri","year":"1995","journal-title":"British Journal of Cancer","ISSN":"https:\/\/id.crossref.org\/issn\/1532-1827","issn-type":"print"},{"issue":"3","key":"51_11045749","first-page":"513","volume":"18","author":"Yoshida","year":"2001","journal-title":"International journal of oncology","ISSN":"https:\/\/id.crossref.org\/issn\/1019-6439","issn-type":"print"},{"issue":"15","key":"52_10416047","doi-asserted-by":"crossref","first-page":"1837","DOI":"10.1101\/gad.14.15.1837","volume":"14","author":"Polakis","year":"2000","journal-title":"Genes &amp; Development","ISSN":"https:\/\/id.crossref.org\/issn\/0890-9369","issn-type":"print"},{"issue":"23","key":"53_5843468","doi-asserted-by":"publisher","first-page":"2833","DOI":"10.1038\/sj.onc.1201462","volume":"15","author":"Porfiri","year":"1997","journal-title":"Oncogene","ISSN":"https:\/\/id.crossref.org\/issn\/0950-9232","issn-type":"print"},{"issue":"1","key":"54_11130549","doi-asserted-by":"publisher","first-page":"53","DOI":"10.1038\/88264","volume":"28","author":"Hovanes","year":"2001","journal-title":"Nature genetics","ISSN":"https:\/\/id.crossref.org\/issn\/1061-4036","issn-type":"print"},{"issue":"6726","key":"55_10781768","doi-asserted-by":"publisher","first-page":"422","DOI":"10.1038\/18884","volume":"398","author":"Tetsu","year":"1999","journal-title":"Nature; Physical Science (London)","ISSN":"https:\/\/id.crossref.org\/issn\/1476-4687","issn-type":"print"},{"issue":"5382","key":"56_6141114","doi-asserted-by":"publisher","first-page":"1509","DOI":"10.1126\/science.281.5382.1509","volume":"281","author":"He","year":"1998","journal-title":"Science","ISSN":"https:\/\/id.crossref.org\/issn\/0036-8075","issn-type":"print"},{"issue":"2","key":"57_20049179","doi-asserted-by":"publisher","first-page":"369","DOI":"10.1083\/jcb.200102028","volume":"154","year":"2001","journal-title":"The Journal of Cell Biology","ISSN":"https:\/\/id.crossref.org\/issn\/0021-9525","issn-type":"print"},{"issue":"3","key":"58_10383860","doi-asserted-by":"publisher","first-page":"576","DOI":"10.1046\/j.1365-2141.2000.02046.x","volume":"109","author":"Park","year":"2000","journal-title":"British journal of haematology","ISSN":"https:\/\/id.crossref.org\/issn\/0007-1048","issn-type":"print"},{"issue":"5","key":"59_10547238","doi-asserted-by":"publisher","first-page":"431","DOI":"10.1080\/10408360091174286","volume":"37","author":"Fosslien","year":"2000","journal-title":"Critical reviews in clinical laboratory sciences","ISSN":"https:\/\/id.crossref.org\/issn\/1040-8363","issn-type":"print"},{"issue":"1","key":"60_16962556","doi-asserted-by":"publisher","first-page":"11","DOI":"10.1038\/35094017","volume":"1","author":"Gupta","year":"2001","journal-title":"Nature reviews. Cancer","ISSN":"https:\/\/id.crossref.org\/issn\/1474-175X","issn-type":"print"},{"key":"61_5963366","doi-asserted-by":"crossref","first-page":"167","DOI":"10.1007\/978-1-4615-5325-0_24","volume":"400A","author":"Seibert","year":"1997","journal-title":"Advances in experimental medicine and biology","ISSN":"https:\/\/id.crossref.org\/issn\/0065-2598","issn-type":"print"},{"key":"62_15856702","first-page":"125","volume":"23","author":"Seibert","year":"1995","journal-title":"Advances in prostaglandin, thromboxane, and leukotriene research","ISSN":"https:\/\/id.crossref.org\/issn\/0732-8141","issn-type":"print"},{"issue":"22","key":"63_6204598","doi-asserted-by":"publisher","first-page":"13313","DOI":"10.1073\/pnas.95.22.13313","volume":"95","author":"Smith","year":"1998","journal-title":"PNAS","ISSN":"https:\/\/id.crossref.org\/issn\/0027-8424","issn-type":"print"},{"issue":"55","key":"64_6428510","doi-asserted-by":"publisher","first-page":"7908","DOI":"10.1038\/sj.onc.1203286","volume":"18","author":"Williams","year":"1999","journal-title":"Oncogene","ISSN":"https:\/\/id.crossref.org\/issn\/0950-9232","issn-type":"print"},{"issue":"5","key":"65_16538354","doi-asserted-by":"publisher","first-page":"803","DOI":"10.1016\/S0092-8674(00)81988-1","volume":"87","author":"Oshima","year":"1996","journal-title":"Cell","ISSN":"https:\/\/id.crossref.org\/issn\/0092-8674","issn-type":"print"},{"issue":"26","key":"66_10362655","doi-asserted-by":"publisher","first-page":"1946","DOI":"10.1056\/NEJM200006293422603","volume":"342","author":"Steinbach","year":"2000","journal-title":"New England Journal of Medicine","ISSN":"https:\/\/id.crossref.org\/issn\/0028-4793","issn-type":"print"},{"issue":"3","key":"67_16902572","first-page":"741","volume":"62","author":"Huerta","year":"2002","journal-title":"Cancer Research","ISSN":"https:\/\/id.crossref.org\/issn\/0008-5472","issn-type":"print"},{"issue":"5","key":"68_16610939","doi-asserted-by":"publisher","first-page":"249","DOI":"10.1006\/scbi.1996.0033","volume":"7","author":"Bilger","year":"1996","journal-title":"Seminars in cancer biology","ISSN":"https:\/\/id.crossref.org\/issn\/1044-579X","issn-type":"print"},{"issue":"1","key":"69_5641767","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1016\/0303-7207(90)90053-B","volume":"70","author":"Koeffler","year":"1990","journal-title":"Molecular and cellular endocrinology","ISSN":"https:\/\/id.crossref.org\/issn\/0303-7207","issn-type":"print"},{"issue":"3-8","key":"70_9793806","doi-asserted-by":"publisher","first-page":"231","DOI":"10.1016\/0960-0760(92)90349-N","volume":"41","author":"Norman","year":"1992","journal-title":"The Journal of steroid biochemistry and molecular biology","ISSN":"https:\/\/id.crossref.org\/issn\/0960-0760","issn-type":"print"}],"container-title":["JNCI Journal of the National Cancer Institute"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/academic.oup.com\/jnci\/article-pdf\/95\/12\/896\/9835201\/896.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,4,26]],"date-time":"2023-04-26T12:20:26Z","timestamp":1682511626000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/jnci\/article-lookup\/doi\/10.1093\/jnci\/95.12.896"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2003,6,18]]},"references-count":70,"journal-issue":{"issue":"12","published-print":{"date-parts":[[2003,6,18]]}},"URL":"https:\/\/doi.org\/10.1093\/jnci\/95.12.896","relation":{},"ISSN":["0027-8874","1460-2105"],"issn-type":[{"value":"0027-8874","type":"print"},{"value":"1460-2105","type":"electronic"}],"subject":[],"published":{"date-parts":[[2003,6,18]]}}}