{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,3]],"date-time":"2026-06-03T06:24:27Z","timestamp":1780467867178,"version":"3.54.1"},"reference-count":45,"publisher":"Oxford University Press (OUP)","issue":"2","license":[{"start":{"date-parts":[[2021,7,29]],"date-time":"2021-07-29T00:00:00Z","timestamp":1627516800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/journals\/pages\/open_access\/funder_policies\/chorus\/standard_publication_model"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2022,2,7]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>Early initiation of breast cancer screening is recommended for high-risk women, including survivors of childhood cancer treated with chest radiation. Recent studies suggest that female survivors of childhood leukemia or sarcoma treated without chest radiation are also at elevated early onset breast cancer risk. However, the potential clinical benefits and cost-effectiveness of early breast cancer screening among these women are uncertain.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Using data from the Childhood Cancer Survivor Study, we adapted 2 Cancer Intervention and Surveillance Modeling Network simulation models to reflect the elevated risks of breast cancer and competing mortality among leukemia and sarcoma survivors. Costs and utility weights were based on published studies and databases. Outcomes included breast cancer deaths averted, false-positive screening results, benign biopsies, and incremental cost-effectiveness ratios.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>In the absence of screening, the lifetime risk of dying from breast cancer among survivors was 6.8% to 7.0% across models. Early initiation of annual mammography with breast magnetic resonance imaging screening between ages 25 and 40 years would avert 52.6% to 64.3% of breast cancer deaths. When costs and quality-of-life impacts were considered, screening starting at age 40 years was the only strategy with an incremental cost-effectiveness ratio below the $100 000 per quality-adjusted life-year (QALY) gained cost-effectiveness threshold ($27 680 to $44 380 per QALY gained across models).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Among survivors of childhood leukemia or sarcoma, early initiation of breast cancer screening at age 40 years may reduce breast cancer deaths by half and is cost-effective. These findings could help inform screening guidelines for survivors treated without chest radiation.<\/jats:p><\/jats:sec>","DOI":"10.1093\/jnci\/djab149","type":"journal-article","created":{"date-parts":[[2021,7,26]],"date-time":"2021-07-26T19:11:57Z","timestamp":1627326717000},"page":"235-244","source":"Crossref","is-referenced-by-count":16,"title":["Breast Cancer Screening Among Childhood Cancer Survivors Treated Without Chest Radiation: Clinical Benefits and Cost-Effectiveness"],"prefix":"10.1093","volume":"114","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-2724-7404","authenticated-orcid":false,"given":"Jennifer M","family":"Yeh","sequence":"first","affiliation":[{"name":"Division of General Pediatrics, Department of Pediatrics, Boston Children\u2019s Hospital, Boston, MA, USA"},{"name":"Department of Pediatrics, Harvard Medical School, Boston, MA, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0840-7855","authenticated-orcid":false,"given":"Kathryn P","family":"Lowry","sequence":"additional","affiliation":[{"name":"Department of Radiology, University of Washington and Seattle Cancer Care Alliance, Seattle, WA, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0010-2827","authenticated-orcid":false,"given":"Clyde B","family":"Schechter","sequence":"additional","affiliation":[{"name":"Department of Family and Social Medicine, Albert Einstein College of Medicine, Bronx, NY, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lisa R","family":"Diller","sequence":"additional","affiliation":[{"name":"Department of Pediatrics, Harvard Medical School, Boston, MA, USA"},{"name":"Dana-Farber\/Boston Children\u2019s Cancer and Blood Disorders Center, Boston, MA, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Grace","family":"O\u2019Brien","sequence":"additional","affiliation":[{"name":"Division of General Pediatrics, Department of Pediatrics, Boston Children\u2019s Hospital, Boston, MA, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5133-1382","authenticated-orcid":false,"given":"Oguzhan","family":"Alagoz","sequence":"additional","affiliation":[{"name":"Department of Industrial and Systems Engineering, University of Wisconsin-Madison, Madison, WI, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gregory T","family":"Armstrong","sequence":"additional","affiliation":[{"name":"Department of Epidemiology and Cancer Control, St. Jude Children\u2019s Research Hospital, Memphis, TN, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"John M","family":"Hampton","sequence":"additional","affiliation":[{"name":"Department of Population Health Sciences and Carbone Cancer Center, University of Wisconsin-Madison, Madison, WI, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6984-2407","authenticated-orcid":false,"given":"Melissa M","family":"Hudson","sequence":"additional","affiliation":[{"name":"Department of Epidemiology and Cancer Control, St. Jude Children\u2019s Research Hospital, Memphis, TN, USA"},{"name":"Department of Oncology, St. Jude Children\u2019s Research Hospital, Memphis, TN, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7405-0906","authenticated-orcid":false,"given":"Wendy","family":"Leisenring","sequence":"additional","affiliation":[{"name":"Fred Hutchinson Cancer Research Center, Seattle, WA, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7208-515X","authenticated-orcid":false,"given":"Qi","family":"Liu","sequence":"additional","affiliation":[{"name":"Department of Public Health Sciences, University of Alberta, Edmonton, Alberta, Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jeanne S","family":"Mandelblatt","sequence":"additional","affiliation":[{"name":"Lombardi Comprehensive Cancer Center, Georgetown University, Washington, DC, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Diana L","family":"Miglioretti","sequence":"additional","affiliation":[{"name":"Department of Public Health Sciences, University of California Davis School of Medicine, Davis, CA, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chaya S","family":"Moskowitz","sequence":"additional","affiliation":[{"name":"Department of Epidemiology and Biostatistics, Memorial Sloan Kettering Cancer Center, New York, NY, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Paul C","family":"Nathan","sequence":"additional","affiliation":[{"name":"The Hospital for Sick Children, Toronto, Ontario, Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Joseph P","family":"Neglia","sequence":"additional","affiliation":[{"name":"Department of Pediatrics, University of Minnesota Medical School"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0806-7894","authenticated-orcid":false,"given":"Kevin C","family":"Oeffinger","sequence":"additional","affiliation":[{"name":"Department of Medicine, Duke School of Medicine and Duke Cancer Institute, Durham, NC, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5971-4660","authenticated-orcid":false,"given":"Amy","family":"Trentham-Dietz","sequence":"additional","affiliation":[{"name":"Department of Population Health Sciences and Carbone Cancer Center, University of Wisconsin-Madison, Madison, WI, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Natasha K","family":"Stout","sequence":"additional","affiliation":[{"name":"Department of Population Medicine, Harvard Medical School and Harvard Pilgrim Health Care Institute, Boston, MA, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[2021,7,29]]},"reference":[{"issue":"21","key":"2022020903140586300_djab149-B1","doi-asserted-by":"crossref","first-page":"2217","DOI":"10.1200\/JCO.2013.54.4601","article-title":"Breast cancer after chest radiation therapy for childhood cancer","volume":"32","author":"Moskowitz","year":"2014","journal-title":"J Clin Oncol"},{"key":"2022020903140586300_djab149-B2","year":"2018"},{"issue":"2","key":"2022020903140586300_djab149-B3","doi-asserted-by":"crossref","first-page":"75","DOI":"10.3322\/canjclin.57.2.75","article-title":"American Cancer Society guidelines for breast screening with MRI as an adjunct to mammography","volume":"57","author":"Saslow","year":"2007","journal-title":"CA Cancer J Clin"},{"key":"2022020903140586300_djab149-B4","year":"2019"},{"issue":"3, pt A","key":"2022020903140586300_djab149-B5","doi-asserted-by":"crossref","first-page":"408","DOI":"10.1016\/j.jacr.2017.11.034","article-title":"Breast cancer screening in women at higher-than-average risk: recommendations from the ACR","volume":"15","author":"Monticciolo","year":"2018","journal-title":"J Am Coll Radiol"},{"key":"2022020903140586300_djab149-B6","doi-asserted-by":"crossref","first-page":"4194","DOI":"10.1200\/JCO.20.00562","article-title":"Updated breast cancer surveillance recommendations for female survivors of childhood, adolescent, and young adult cancer from the International Guideline Harmonization Group","author":"Mulder","year":"2020","journal-title":"J Clin Oncol"},{"issue":"9","key":"2022020903140586300_djab149-B7","doi-asserted-by":"crossref","first-page":"910","DOI":"10.1200\/JCO.2015.62.3314","article-title":"Breast cancer risk in childhood cancer survivors without a history of chest radiotherapy: a report from the Childhood Cancer Survivor Study","volume":"34","author":"Henderson","year":"2016","journal-title":"J Clin Oncol"},{"issue":"34","key":"2022020903140586300_djab149-B8","doi-asserted-by":"crossref","first-page":"3310","DOI":"10.1200\/JCO.19.00129","article-title":"Chemotherapy and risk of subsequent malignant neoplasms in the Childhood Cancer Survivor Study cohort","volume":"37","author":"Turcotte","year":"2019","journal-title":"J Clin Oncol"},{"issue":"12","key":"2022020903140586300_djab149-B9","doi-asserted-by":"crossref","first-page":"1171","DOI":"10.1001\/jamapediatrics.2019.3807","article-title":"Association of breast cancer risk after childhood cancer with radiation dose to the breast and anthracycline use: a report from the Childhood Cancer Survivor Study","volume":"173","author":"Veiga","year":"2019","journal-title":"JAMA Pediatr"},{"issue":"20","key":"2022020903140586300_djab149-B10","doi-asserted-by":"crossref","first-page":"2288","DOI":"10.1200\/JCO.2016.71.6902","article-title":"Long-term risk of subsequent malignant neoplasms after treatment of childhood cancer in the DCOG LATER study cohort: role of chemotherapy","volume":"35","author":"Teepen","year":"2017","journal-title":"J Clin Oncol"},{"issue":"19","key":"2022020903140586300_djab149-B11","doi-asserted-by":"crossref","first-page":"1647","DOI":"10.1200\/JCO.18.01099","article-title":"Subsequent breast cancer in female childhood cancer survivors in the St Jude Lifetime Cohort Study (SJLIFE)","volume":"37","author":"Ehrhardt","year":"2019","journal-title":"J Clin Oncol"},{"issue":"24","key":"2022020903140586300_djab149-B12","doi-asserted-by":"crossref","first-page":"2120","DOI":"10.1200\/JCO.18.02219","article-title":"Mortality after breast cancer among survivors of childhood cancer: a report from the Childhood Cancer Survivor Study","volume":"37","author":"Moskowitz","year":"2019","journal-title":"J Clin Oncol"},{"issue":"34","key":"2022020903140586300_djab149-B13","doi-asserted-by":"crossref","first-page":"5088","DOI":"10.1200\/JCO.2010.29.5683","article-title":"Long-term survival among patients with Hodgkin\u2019s lymphoma who developed breast cancer: a population-based study","volume":"28","author":"Milano","year":"2010","journal-title":"J Clin Oncol"},{"issue":"5","key":"2022020903140586300_djab149-B14","doi-asserted-by":"crossref","first-page":"331","DOI":"10.7326\/M19-3481","article-title":"Clinical benefits, harms, and cost-effectiveness of breast cancer screening for survivors of childhood cancer treated with chest radiation: a comparative modeling study","volume":"173","author":"Yeh","year":"2020","journal-title":"Ann Intern Med"},{"issue":"14","key":"2022020903140586300_djab149-B15","doi-asserted-by":"crossref","first-page":"2308","DOI":"10.1200\/JCO.2009.22.3339","article-title":"The Childhood Cancer Survivor Study: a National Cancer Institute-supported resource for outcome and intervention research","volume":"27","author":"Robison","year":"2009","journal-title":"J Clin Oncol"},{"issue":"10","key":"2022020903140586300_djab149-B16","doi-asserted-by":"crossref","first-page":"738","DOI":"10.7326\/0003-4819-151-10-200911170-00010","article-title":"Effects of mammography screening under different screening schedules: Model estimates of potential benefits and harms","volume":"151","author":"Mandelblatt","year":"2009","journal-title":"Ann Intern Med"},{"issue":"4","key":"2022020903140586300_djab149-B17","doi-asserted-by":"crossref","first-page":"215","DOI":"10.7326\/M15-1536","article-title":"Collaborative modeling of the benefits and harms associated with different U.S. breast cancer screening strategies","volume":"164","author":"Mandelblatt","year":"2016","journal-title":"Ann Intern Med"},{"issue":"3","key":"2022020903140586300_djab149-B18","doi-asserted-by":"crossref","first-page":"350","DOI":"10.1001\/jamaoncol.2019.5582","article-title":"Life expectancy of adult survivors of childhood cancer over 3 decades","volume":"6","author":"Yeh","year":"2020","journal-title":"JAMA Oncol"},{"key":"2022020903140586300_djab149-B19","doi-asserted-by":"crossref","first-page":"99S","DOI":"10.1177\/0272989X17711927","article-title":"The University of Wisconsin breast cancer epidemiology simulation model: an update","volume":"38(suppl 1","author":"Alagoz","year":"2018","journal-title":"Med Decis Making"},{"key":"2022020903140586300_djab149-B20","doi-asserted-by":"crossref","first-page":"9S","DOI":"10.1177\/0272989X17700624","article-title":"Common model inputs used in CISNET collaborative breast cancer modeling","volume":"38(suppl 1","author":"Mandelblatt","year":"2018","journal-title":"Med Decis Making"},{"key":"2022020903140586300_djab149-B21","doi-asserted-by":"crossref","first-page":"66S","DOI":"10.1177\/0272989X17698685","article-title":"Structure, function, and applications of the Georgetown-Einstein (GE) breast cancer simulation model","volume":"38(suppl 1","author":"Schechter","year":"2018","journal-title":"Med Decis Making"},{"issue":"2","key":"2022020903140586300_djab149-B22","doi-asserted-by":"crossref","first-page":"154","DOI":"10.1001\/jama.2017.19130","article-title":"Association of screening and treatment with breast cancer mortality by molecular subtype in US Women, 2000-2012","volume":"319","author":"Plevritis","year":"2018","journal-title":"JAMA"},{"key":"2022020903140586300_djab149-B23","doi-asserted-by":"crossref","first-page":"140S","DOI":"10.1177\/0272989X17718168","article-title":"Comparing CISNET breast cancer incidence and mortality predictions to observed clinical trial results of mammography screening from ages 40 to 49","volume":"38(suppl 1","author":"van den Broek","year":"2018","journal-title":"Med Decis Making"},{"key":"2022020903140586300_djab149-B24","author":"Mandelblatt","year":"2015"},{"issue":"6","key":"2022020903140586300_djab149-B25","doi-asserted-by":"crossref","first-page":"905","DOI":"10.1158\/1055-9965.EPI-14-1286","article-title":"The contribution of mammography screening to breast cancer incidence trends in the United States: an updated age-period-cohort model","volume":"24","author":"Gangnon","year":"2015","journal-title":"Cancer Epidemiol Biomarkers Prev"},{"issue":"18","key":"2022020903140586300_djab149-B26","doi-asserted-by":"crossref","first-page":"2466","DOI":"10.1200\/JCO.2010.32.4079","article-title":"Characteristics and outcomes of breast cancer in women with and without a history of radiation for Hodgkin\u2019s lymphoma: a multi-institutional, matched cohort study","volume":"29","author":"Elkin","year":"2011","journal-title":"J Clin Oncol"},{"issue":"11","key":"2022020903140586300_djab149-B27","doi-asserted-by":"crossref","DOI":"10.1093\/jnci\/dju289","article-title":"Effects of screening and systemic adjuvant therapy on ER-specific US breast cancer mortality","volume":"106","author":"Munoz","year":"2014","journal-title":"J Natl Cancer Inst"},{"issue":"suppl 1","key":"2022020903140586300_djab149-B28","doi-asserted-by":"crossref","first-page":"112S","DOI":"10.1177\/0272989X17743244","article-title":"Comparing CISNET breast cancer models using the maximum clinical incidence reduction methodology","volume":"38","author":"van den Broek","year":"2018","journal-title":"Med Decis Making"},{"issue":"4","key":"2022020903140586300_djab149-B29","doi-asserted-by":"crossref","first-page":"349","DOI":"10.1200\/JCO.2014.56.6232","article-title":"Magnetic resonance imaging improves breast screening sensitivity in BRCA mutation carriers age &gt;\/= 50 years: evidence from an individual patient data meta-analysis","volume":"33","author":"Phi","year":"2015","journal-title":"J Clin Oncol"},{"issue":"1","key":"2022020903140586300_djab149-B30","doi-asserted-by":"crossref","first-page":"44","DOI":"10.1148\/radiol.2017162033","article-title":"Performance benchmarks for screening breast MR imaging in community practice","volume":"285","author":"Lee","year":"2017","journal-title":"Radiology"},{"key":"2022020903140586300_djab149-B31","year":"2015"},{"issue":"9814","key":"2022020903140586300_djab149-B32","doi-asserted-by":"crossref","first-page":"432","DOI":"10.1016\/S0140-6736(11)61625-5","article-title":"Comparisons between different polychemotherapy regimens for early breast cancer: meta-analyses of long-term outcome among 100,000 women in 123 randomised trials","volume":"379","author":"Peto","year":"2012","journal-title":"Lancet"},{"key":"2022020903140586300_djab149-B33","doi-asserted-by":"crossref","first-page":"24S","DOI":"10.1177\/0272989X17717981","article-title":"Contribution of breast cancer to overall mortality for US women","volume":"38(suppl 1","author":"Gangnon","year":"2018","journal-title":"Med Decis Making"},{"issue":"6","key":"2022020903140586300_djab149-B34","doi-asserted-by":"crossref","first-page":"dju092","DOI":"10.1093\/jnci\/dju092","article-title":"Benefits, harms, and costs for breast cancer screening after US implementation of digital mammography","volume":"106","author":"Stout","year":"2014","journal-title":"J Natl Cancer Inst"},{"issue":"6","key":"2022020903140586300_djab149-B35","doi-asserted-by":"crossref","first-page":"582","DOI":"10.1093\/jnci\/djz184","article-title":"Long-term outcomes and cost-effectiveness of breast cancer screening with digital breast tomosynthesis in the United States","volume":"112","author":"Lowry","year":"2020","journal-title":"J Natl Cancer Inst"},{"issue":"55","key":"2022020903140586300_djab149-B36","doi-asserted-by":"crossref","first-page":"22","DOI":"10.1093\/jncimonographs\/lgz032","article-title":"Cancer-attributable medical costs for colorectal cancer patients by phases of care: what is the effect of a prior cancer history?","volume":"2020","author":"Mariotto","year":"2020","journal-title":"J Natl Cancer Inst Monogr"},{"issue":"7","key":"2022020903140586300_djab149-B37","doi-asserted-by":"crossref","first-page":"1304","DOI":"10.1158\/1055-9965.EPI-19-1534","article-title":"Medical care costs associated with cancer survivorship in the United States","volume":"29","author":"Mariotto","year":"2020","journal-title":"Cancer Epidemiol Biomarkers Prev"},{"issue":"9","key":"2022020903140586300_djab149-B38","doi-asserted-by":"crossref","DOI":"10.1093\/jnci\/djw046","article-title":"Chronic conditions and utility-based health-related quality of life in adult childhood cancer survivors","volume":"108","author":"Yeh","year":"2016","journal-title":"J Natl Cancer Inst"},{"issue":"4","key":"2022020903140586300_djab149-B39","doi-asserted-by":"crossref","first-page":"538","DOI":"10.1002\/ijc.2910490411","article-title":"The impact of a breast cancer screening programme on quality-adjusted life-years","volume":"49","author":"de Haes","year":"1991","journal-title":"Int J Cancer"},{"issue":"11","key":"2022020903140586300_djab149-B40","doi-asserted-by":"crossref","first-page":"774","DOI":"10.1093\/jnci\/djj210","article-title":"Retrospective cost-effectiveness analysis of screening mammography","volume":"98","author":"Stout","year":"2006","journal-title":"J Natl Cancer Inst"},{"key":"2022020903140586300_djab149-B41","volume-title":"Cost-Effectiveness in Health and Medicine","author":"Neumann","year":"2017","edition":"2nd ed"},{"issue":"6","key":"2022020903140586300_djab149-B42","doi-asserted-by":"crossref","first-page":"796","DOI":"10.1016\/j.jval.2012.06.012","article-title":"Modeling good research practices\u2013overview: a report of the ISPOR-SMDM Modeling Good Research Practices Task Force\u20131","volume":"15","author":"Caro","year":"2012","journal-title":"Value Health"},{"issue":"9","key":"2022020903140586300_djab149-B43","doi-asserted-by":"crossref","first-page":"796","DOI":"10.1056\/NEJMp1405158","article-title":"Updating cost-effectiveness\u2013the curious resilience of the $50,000-per-QALY threshold","volume":"371","author":"Neumann","year":"2014","journal-title":"N Engl J Med"},{"key":"2022020903140586300_djab149-B44","doi-asserted-by":"crossref","first-page":"926","DOI":"10.1200\/PO.20.00141","article-title":"Subsequent neoplasm risk associated with rare variants in DNA damage response and clinical radiation sensitivity syndrome genes in the Childhood Cancer Survivor Study","volume":"4","author":"Morton","year":"2020","journal-title":"J Clin Oncol Precis Oncol"},{"issue":"15","key":"2022020903140586300_djab149-B45","doi-asserted-by":"crossref","first-page":"1599","DOI":"10.1001\/jama.2015.12783","article-title":"Breast cancer screening for women at average risk: 2015 guideline update from the American Cancer Society","volume":"314","author":"Oeffinger","year":"2015","journal-title":"JAMA"}],"container-title":["JNCI: Journal of the National Cancer Institute"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/academic.oup.com\/jnci\/advance-article-pdf\/doi\/10.1093\/jnci\/djab149\/40349999\/djab149.pdf","content-type":"application\/pdf","content-version":"am","intended-application":"syndication"},{"URL":"https:\/\/academic.oup.com\/jnci\/article-pdf\/114\/2\/235\/42424881\/djab149.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/academic.oup.com\/jnci\/article-pdf\/114\/2\/235\/42424881\/djab149.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,9,5]],"date-time":"2024-09-05T02:54:47Z","timestamp":1725504887000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/jnci\/article\/114\/2\/235\/6330765"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,7,29]]},"references-count":45,"journal-issue":{"issue":"2","published-online":{"date-parts":[[2021,7,29]]},"published-print":{"date-parts":[[2022,2,7]]}},"URL":"https:\/\/doi.org\/10.1093\/jnci\/djab149","relation":{},"ISSN":["0027-8874","1460-2105"],"issn-type":[{"value":"0027-8874","type":"print"},{"value":"1460-2105","type":"electronic"}],"subject":[],"published-other":{"date-parts":[[2022,2,1]]},"published":{"date-parts":[[2021,7,29]]}}}