{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,12]],"date-time":"2026-05-12T17:05:21Z","timestamp":1778605521810,"version":"3.51.4"},"reference-count":40,"publisher":"Oxford University Press (OUP)","issue":"3","license":[{"start":{"date-parts":[[2021,10,1]],"date-time":"2021-10-01T00:00:00Z","timestamp":1633046400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/journals\/pages\/open_access\/funder_policies\/chorus\/standard_publication_model"}],"funder":[{"name":"National Cancer Institute of Canada through the Canadian Cancer Society (NCIC","award":["12018"],"award-info":[{"award-number":["12018"]}]},{"name":"NCIC","award":["13010"],"award-info":[{"award-number":["13010"]}]},{"name":"NCIC","award":["17323"],"award-info":[{"award-number":["17323"]}]},{"name":"Alberta Cancer Board (ACB","award":["22190"],"award-info":[{"award-number":["22190"]}]},{"name":"Canadian Institutes of Health Research and the Alberta Heritage Foundation for Medical Research\/Alberta Innovates (AHFMR\/Alberta Innovates"},{"name":"Cook and KS Courneya held Canada Research Chairs and LS Cook also received career award funding from AHFMR"},{"DOI":"10.13039\/100000054","name":"US National Cancer Institute (NCI","doi-asserted-by":"crossref","award":["P30CA118100"],"award-info":[{"award-number":["P30CA118100"]}],"id":[{"id":"10.13039\/100000054","id-type":"DOI","asserted-by":"crossref"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2022,3,8]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>Disease-free survival (DFS) and overall survival (OS) associations with anthropometric measures of obesity and changes in these exposures remain unknown among endometrial cancer survivors.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Endometrial cancer survivors diagnosed between 2002 and 2006 completed direct anthropometric measurements and self-reported lifetime weight history during in-person interviews approximately 4\u2009months after diagnosis (peridiagnosis) and approximately 3\u2009years after diagnosis (follow-up). Participants were followed-up until death or March 20, 2019. Cox proportional regression was used to estimate multivariable-adjusted hazard ratios (HRs) and 95% confidence intervals (CIs) for body mass index (BMI), weight, waist circumference, and waist-hip ratio with DFS and OS. Statistical tests were 2-sided.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>A total of 540 and 425 cancer survivors were assessed peridiagnosis and follow-up, respectively. During the median 14.2\u2009years of follow-up (range\u2009=\u20090.3-16.5\u2009years), 132 participants had a recurrence and\/or died (DFS), with 111 deaths overall (OS). Reduced DFS was noted with greater recalled weight 1 year before diagnosis (HR\u2009=\u20091.88, 95% CI\u2009=\u20091.15 to 3.07), BMI 1 year before diagnosis (HR\u2009=\u20091.88, 95% CI\u2009=\u20091.09 to 3.22), and measured peridiagnosis BMI (HR\u2009=\u20092.04, 95% CI\u2009=\u20091.18 to 3.53). Measured peridiagnosis waist circumference of at least 88\u2009cm was associated with decreased DFS (HR\u2009=\u20091.94, 95% CI\u2009=\u20091.24 to 3.03) and OS (HR\u2009=\u20091.90, 95% CI\u2009=\u20091.16 to 3.13). A twofold decrease in DFS and OS was associated with a BMI of at least 5% or weight change from 1 year before diagnosis to peridiagnosis. No associations were observed for the assessment during follow-up.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>One-year before- and peridiagnosis anthropometric measures of obesity were associated with reduced survival among endometrial cancer survivors. Anthropometric changes from 1 year before to peridiagnosis may provide an important indication of future survival in this population.<\/jats:p><\/jats:sec>","DOI":"10.1093\/jnci\/djab197","type":"journal-article","created":{"date-parts":[[2021,9,30]],"date-time":"2021-09-30T16:01:46Z","timestamp":1633017706000},"page":"409-418","source":"Crossref","is-referenced-by-count":14,"title":["Prospective Cohort Study of Pre- and Postdiagnosis Obesity and Endometrial Cancer Survival"],"prefix":"10.1093","volume":"114","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-1723-8421","authenticated-orcid":false,"given":"Ren\u00e9e L","family":"Kokts-Porietis","sequence":"first","affiliation":[{"name":"Department of Cancer Epidemiology and Prevention Research, Cancer Care Alberta, Alberta Health Services, Calgary, AB, Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jessica","family":"McNeil","sequence":"additional","affiliation":[{"name":"Department of Kinesiology, Faculty of 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