{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,23]],"date-time":"2026-10-23T20:06:34Z","timestamp":1792785994974,"version":"4.5.0"},"reference-count":18,"publisher":"Oxford University Press (OUP)","issue":"2","funder":[{"name":"Surveillance Research Program, Division of Cancer Control and Population Sciences"},{"DOI":"10.13039\/100000054","name":"National Cancer Institute","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100000054","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2024,2,8]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>The COVID-19 pandemic has had a profound global impact on health-care systems and patient outcomes. However, the specific effects of the pandemic on cancer incidence rates in the United States during its initial year remain unknown.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>In this study, we analyzed data from the Surveillance, Epidemiology, and End Results\u201322 registries, which encompass approximately 50% of the US population. We investigated changes in monthly incidence rates stratified by various factors, including cancer type, stage, age group, sex, race and ethnicity, socioeconomic status, rural-urban status, and registry locations. We compared the incidence rates observed during the pandemic with those from the previous year.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Our findings revealed a decline in incidence rates for all cancer sites combined starting in March 2020, coinciding with the implementation of stay-at-home orders. This decline reached its lowest point in April 2020 and persisted at a lower level until May 2020. Notably, compared with April 2019, the incidence rates in April 2020 dropped by 48.1% and did not consistently return to prepandemic levels. The reduction in cancer rates was more pronounced in urban and affluent counties. Across all cancer types, there was a statistically significant decrease in incidence rates during the pandemic, with the largest declines observed in thyroid (71.2%), prostate (57.9%), breast (54.9%), and colon and rectum cancers (54.1%). Furthermore, these decreases were primarily observed in early stage rather than late-stage disease.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>The COVID-19 pandemic had a statistically significant impact on cancer outcomes. Monitoring long-term consequences of the pandemic on cancer incidence, stage at diagnosis, and mortality trends will be crucial.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1093\/jnci\/djad205","type":"journal-article","created":{"date-parts":[[2023,9,29]],"date-time":"2023-09-29T16:29:15Z","timestamp":1696004955000},"page":"208-215","source":"Crossref","is-referenced-by-count":48,"title":["Cancer and COVID-19: US cancer incidence rates during the first year of the pandemic"],"prefix":"10.1093","volume":"116","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-1989-1478","authenticated-orcid":false,"given":"Nadia","family":"Howlader","sequence":"first","affiliation":[{"name":"Surveillance Research Program, Division of Cancer Control and Population Sciences, National Cancer Institute , Rockville, MD, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3116-6065","authenticated-orcid":false,"given":"Manami","family":"Bhattacharya","sequence":"additional","affiliation":[{"name":"Surveillance Research Program, Division of Cancer Control and Population Sciences, National Cancer Institute , Rockville, MD, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Steve","family":"Scoppa","sequence":"additional","affiliation":[{"name":"Information Management Services , Calverton, MD, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Daniel","family":"Miller","sequence":"additional","affiliation":[{"name":"Information Management Services , Calverton, MD, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6997-4004","authenticated-orcid":false,"given":"Anne-Michelle","family":"Noone","sequence":"additional","affiliation":[{"name":"Surveillance Research Program, Division of Cancer Control and Population Sciences, National Cancer Institute , Rockville, MD, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2477-0379","authenticated-orcid":false,"given":"Serban","family":"Negoita","sequence":"additional","affiliation":[{"name":"Surveillance Research Program, Division of Cancer Control and Population Sciences, National Cancer Institute , Rockville, MD, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kathy","family":"Cronin","sequence":"additional","affiliation":[{"name":"Surveillance Research Program, Division of Cancer Control and Population Sciences, National Cancer Institute , Rockville, MD, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2423-1834","authenticated-orcid":false,"given":"Angela","family":"Mariotto","sequence":"additional","affiliation":[{"name":"Surveillance Research Program, Division of Cancer Control and Population Sciences, National Cancer Institute , Rockville, MD, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[2023,10,5]]},"reference":[{"issue":"6","key":"2024020820201026700_djad205-B1","doi-asserted-by":"publisher","first-page":"907","DOI":"10.1093\/jnci\/djab122","article-title":"Association of the COVID-19 Pandemic With Patterns of Statewide Cancer Services","volume":"114","author":"Yabroff","year":"2022","journal-title":"J Natl Cancer Inst"},{"key":"2024020820201026700_djad205-B2","doi-asserted-by":"publisher","author":"Negoita","DOI":"10.1002\/cncr.35026"},{"issue":"4","key":"2024020820201026700_djad205-B3","doi-asserted-by":"publisher","first-page":"2087","DOI":"10.1245\/s10434-022-12935-w","article-title":"Evaluation of the impact of the COVID-19 pandemic on reliability of cancer surveillance data in the national cancer database","volume":"30","author":"Nogueira","year":"2023","journal-title":"Ann Surg 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