{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,24]],"date-time":"2026-08-24T23:33:56Z","timestamp":1787614436133,"version":"build-2736575974"},"reference-count":23,"publisher":"Oxford University Press (OUP)","issue":"8","license":[{"start":{"date-parts":[[2026,1,7]],"date-time":"2026-01-07T00:00:00Z","timestamp":1767744000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/pages\/standard-publication-reuse-rights"}],"funder":[{"name":"Intramural Research Department"},{"DOI":"10.13039\/100000048","name":"American Cancer Society","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100000048","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000054","name":"National Cancer Institute","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100000054","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100011541","name":"Division of Cancer Epidemiology and Genetics","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100011541","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2026,8,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>Previous cervical cancer incidence trend analyses primarily used period-based approaches, limiting assessment of generational risk shifts against the backdrop of human papillomavirus (HPV) vaccination. Using US Cancer Statistics data and age-period-cohort modeling, we estimated fitted incidence rates at ages 30-31 across birth cohorts (1917-1919 to 1999-2001), adjusted for period deviation. Incidence rates decreased by 1.9% per birth year (95% confidence interval [CI] = \u22122.1% to \u22121.8%) up to 1951-1953 cohorts, then decelerated to 0.3% annually (95% CI = \u22120.4% to \u22120.2%). Starting with 1987-1989 cohorts, incidence rates dropped sharply by 10.5% annually (95% CI = \u221212.7% to \u22128.4%). Compared with 1970-1979 cohorts, 1990-1999 cohorts had a 54% lower incidence rate (10.2 vs. 4.7 per 100\u2009000; rate ratio\u2009=\u20090.46; 95% CI = 0.42 to 0.50). The markedly lower risk among post\u20131987-1989 cohorts suggests a future reduction in population-level burden as these cohorts age. The finding also has implications for reinforcing HPV vaccination efforts and informing discussions on raising the screening initiation age.<\/jats:p>","DOI":"10.1093\/jnci\/djaf374","type":"journal-article","created":{"date-parts":[[2026,1,5]],"date-time":"2026-01-05T12:19:29Z","timestamp":1767615569000},"page":"1532-1536","source":"Crossref","is-referenced-by-count":2,"title":["Cervical cancer incidence rates by birth cohort against the backdrop of human papillomavirus vaccination in the United States"],"prefix":"10.1093","volume":"118","author":[{"ORCID":"https:\/\/orcid.org\/0009-0007-9457-0950","authenticated-orcid":false,"given":"Chenxi","family":"Jiang","sequence":"first","affiliation":[{"name":"Surveillance, Prevention, & Health Services Research, American Cancer Society , Atlanta, GA,","place":["United States"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6349-9126","authenticated-orcid":false,"given":"Philip 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