{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,5]],"date-time":"2026-03-05T00:05:38Z","timestamp":1772669138478,"version":"3.50.1"},"reference-count":95,"publisher":"Oxford University Press (OUP)","license":[{"start":{"date-parts":[[2026,1,30]],"date-time":"2026-01-30T00:00:00Z","timestamp":1769731200000},"content-version":"am","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/pages\/standard-publication-reuse-rights"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>Pediatric Hodgkin lymphoma (pHL) is a highly curable malignancy in children, adolescents, and young adults, and current treatment strategies aim to minimize adverse late effects. Many patients are enrolled in clinical trials with centralized review for both initial and interim staging. Although academic guidelines provide a structured framework for image interpretation, real-world clinical scenarios sometimes present imaging pitfalls that require nuanced judgment. Morphological and metabolic imaging pitfalls refer to misinterpretation of findings that occur during staging, disease evaluation, or post-treatment surveillance. In pHL, such pitfalls may result from suboptimal imaging conditions, concurrent inflammatory, infectious, or other findings. These findings do not indicate neoplastic disease but rather are manifestations of other processes specific to each tissue or organ. This Staging, Evaluation, and Response Criteria Harmonization for Childhood, Adolescent, and Young Adult Hodgkin Lymphoma (SEARCH for CAYAHL) initiative represents a transatlantic collaboration among multidisciplinary professionals, aiming to disseminate the insights gained from decades of centralized review experience in North American and European clinical trials. This article aims to optimize patient care by integrating imaging and clinical expertise in disease staging and surveillance. Although not intended as a comprehensive staging guide, it highlights recurrent imaging pitfalls that may lead to incorrect staging or response assessment. By encouraging interdisciplinary exchange, this work seeks to complement existing literature and serve as a troubleshooting guide for situations where clinical realities diverge from academic paradigms.<\/jats:p>","DOI":"10.1093\/jnci\/djag016","type":"journal-article","created":{"date-parts":[[2026,1,27]],"date-time":"2026-01-27T12:10:18Z","timestamp":1769515818000},"source":"Crossref","is-referenced-by-count":0,"title":["Imaging pitfalls in pediatric, adolescent, and young adult Hodgkin lymphoma: a SEARCH for CAYAHL initiative to bridge multidisciplinary patient care"],"prefix":"10.1093","author":[{"ORCID":"https:\/\/orcid.org\/0009-0005-0407-3228","authenticated-orcid":false,"given":"Nawar","family":"Dakhallah","sequence":"first","affiliation":[{"name":"Division of Haematology\/Oncology, Department of Paediatrics, CHU Sainte-Justine , Montreal, Qu\u00e9bec,","place":["Canada"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5550-1481","authenticated-orcid":false,"given":"Jonas","family":"Steglich","sequence":"additional","affiliation":[{"name":"Department of Diagnostic and Interventional Radiology, Heart Center Leipzig , Leipzig,","place":["Germany"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0009-0008-8054-0635","authenticated-orcid":false,"given":"Claire","family":"Gowdy","sequence":"additional","affiliation":[{"name":"Department of Radiology and Nuclear Medicine, BC Children\u2019s Hospital , Vancouver,","place":["Canada"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0037-6967","authenticated-orcid":false,"given":"Sarah A","family":"Milgrom","sequence":"additional","affiliation":[{"name":"Department of Radiation Oncology, University of Colorado , Aurora, CO,","place":["United States"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1094-282X","authenticated-orcid":false,"given":"Adina L","family":"Alazraki","sequence":"additional","affiliation":[{"name":"Department of Radiology, Emory University School of Medicine , Atlanta, GA,","place":["United States"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8367-2002","authenticated-orcid":false,"given":"Sharon M","family":"Castellino","sequence":"additional","affiliation":[{"name":"Department of Pediatrics, Emory University School of Medicine and Aflac Cancer and Blood Disorders Center, Children\u2019s Healthcare of Atlanta , Atlanta, GA,","place":["United States"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Karin","family":"Dieckmann","sequence":"additional","affiliation":[{"name":"Department of Radiation Oncology, Medical University of Vienna , Vienna,","place":["Austria"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4182-9355","authenticated-orcid":false,"given":"Jamie E","family":"Flerlage","sequence":"additional","affiliation":[{"name":"Division of Pediatric Hematology\/Oncology, Department of Pediatrics, University of Rochester Medical Center , Rochester, NY,","place":["United States"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9454-0857","authenticated-orcid":false,"given":"Mallorie B","family":"Heneghan","sequence":"additional","affiliation":[{"name":"Division of Pediatric Hematology\/Oncology, Department of Pediatrics, Primary Children\u2019s Hospital, University of Utah , Salt Lake City, UT,","place":["United States"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1473-3937","authenticated-orcid":false,"given":"Kara M","family":"Kelly","sequence":"additional","affiliation":[{"name":"Department of Pediatrics, Roswell Park Comprehensive Cancer Center, University at Buffalo Jacobs School of Medicine and Biomedical Sciences , Buffalo, NY,","place":["United States"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6747-7338","authenticated-orcid":false,"given":"Hollie A","family":"Lai","sequence":"additional","affiliation":[{"name":"Department of Radiology, Children\u2019s Health of Orange County , Orange, CA,","place":["United States"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8205-8665","authenticated-orcid":false,"given":"Christine","family":"Mauz-K\u00f6rholz","sequence":"additional","affiliation":[{"name":"Pediatric Hematology and Oncology, Justus-Liebig-University of Giessen , Giessen,","place":["Germany"]},{"name":"Medical Faculty of the Martin-Luther University of Halle-Wittenberg , Halle,","place":["Germany"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kathleen M","family":"McCarten","sequence":"additional","affiliation":[{"name":"Quality Assurance Review Center (QARC)\/Imaging and Radiation Oncology Core Group (IROC), Diagnostic Imaging and Pediatrics, Warren Alpert Medical School , Providence, RI,","place":["United States"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0028-9724","authenticated-orcid":false,"given":"Reena","family":"Pabari","sequence":"additional","affiliation":[{"name":"Division of Haematology\/Oncology, Department of Paediatrics, Hospital for Sick Children, University of Toronto , Toronto, Ontario,","place":["Canada"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2624-0868","authenticated-orcid":false,"given":"Monica","family":"Palese","sequence":"additional","affiliation":[{"name":"Division of Pediatric Hematology\/Oncology, 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