{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,2]],"date-time":"2026-11-02T17:26:30Z","timestamp":1793640390725,"version":"4.5.1"},"reference-count":37,"publisher":"Oxford University Press (OUP)","funder":[{"name":"the Intramural Research Program of the National Institutes of Health"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>In the United States, cervical cancer rates in women with HIV are notably higher than the general population. Including hysterectomized women in cervical cancer rates underestimates incidence and may misguide prevention programs. We estimated the hysterectomy-corrected incidence rates (IR) of cervical cancer among women with HIV.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>We used data from the HIV\/AIDS Cancer Match study, linking 14 HIV and cancer registries in the United States. We calculated age-standardized IRs (ASIRs) of cervical cancer before and after hysterectomy correction using hysterectomy prevalence estimates from the 2001 to 2019 Behavioral Risk Factor Surveillance System by age, race\/ethnicity, and histology. We used Poisson regression to estimate IR ratios (IRR) comparing 2005 to 2009, 2010 to 2014, and 2015 to 2019 to 2001 to 2004, adjusted for race\/ethnicity, age, and region.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>During 2001 to 2019, there were 933 cervical cancer cases in 1\u00a0966\u00a0943 person-years (uncorrected ASIR = 47.4 per 100\u00a0000) and 1\u00a0597\u00a0742 person-years after correction (ASIR = 58.4). Hysterectomy correction increased the ASIR by 28% among Black women (50.1 vs 64.1, P\u2009&amp;lt;\u2009.0001), 18% among Hispanic women (51.7 vs 61.2, P\u2009=\u2009.07), and 20% among White women (30.8 vs 36.9, P\u2009=\u2009.26). Uncorrected ASIRs peaked at ages 40-49 and declined at older ages, while hysterectomy-corrected ASIRs remained highest at ages 40-49 but declined less with age, with similar rates among women aged 50-59 and 60-84. Compared with 2001 to 2004, corrected ASIRs were lower in 2005 to 2009 (IRR = 0.79, 95% CI = 0.65 to 0.96); 2010 to 2014 (IRR = 0.75, 95% CI = 0.61 to 0.91); and 2015 to 2019 (IRR = 0.78, 95% CI = 0.63 to 0.97).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>Without hysterectomy correction, the most pronounced underestimation of cervical cancer ASIRs among women with HIV were observed among Black women and \u226550-year-old women.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1093\/jnci\/djag352","type":"journal-article","created":{"date-parts":[[2026,10,1]],"date-time":"2026-10-01T11:53:40Z","timestamp":1790855620000},"source":"Crossref","is-referenced-by-count":0,"title":["Hysterectomy-corrected incidence of cervical cancer among women with HIV in the United States, 2001-2019"],"prefix":"10.1093","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-9210-172X","authenticated-orcid":false,"given":"Adino Tesfahun","family":"Tsegaye","sequence":"first","affiliation":[{"name":"Division of Cancer Epidemiology and Genetics, National Cancer Institute , Rockville, MD,","place":["United States"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6073-2591","authenticated-orcid":false,"given":"Aim\u00e9e R","family":"Kreimer","sequence":"additional","affiliation":[{"name":"Division of Cancer Epidemiology and Genetics, National Cancer Institute , Rockville, MD,","place":["United States"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7064-4424","authenticated-orcid":false,"given":"Jaimie Z","family":"Shing","sequence":"additional","affiliation":[{"name":"Division of Cancer Epidemiology and Genetics, National Cancer Institute , Rockville, MD,","place":["United 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Patricia","family":"Ortiz","sequence":"additional","affiliation":[{"name":"Division of Cancer Control and Population Sciences, University of Puerto Rico Comprehensive Cancer Center , San Juan, PR,","place":["United States"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9019-8804","authenticated-orcid":false,"given":"Karen","family":"Pawlish","sequence":"additional","affiliation":[{"name":"New Jersey Department of Health, New Jersey State Cancer Registry , Trenton, NJ,","place":["United States"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1251-0836","authenticated-orcid":false,"given":"Nicolas","family":"Wentzensen","sequence":"additional","affiliation":[{"name":"Division of Cancer Epidemiology and Genetics, National Cancer Institute , Rockville, MD,","place":["United States"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eric A","family":"Engels","sequence":"additional","affiliation":[{"name":"Division of Cancer Epidemiology and Genetics, National Cancer Institute , Rockville, MD,","place":["United States"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Meredith S","family":"Shiels","sequence":"additional","affiliation":[{"name":"Division of Cancer Epidemiology and Genetics, National Cancer Institute , Rockville, MD,","place":["United States"]}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[2026,10,3]]},"reference":[{"key":"2026110211320337100_djag352-B1","doi-asserted-by":"publisher","first-page":"1851","DOI":"10.1097\/QAD.0000000000002962","article-title":"Cervical cancer incidence stratified by age in women with HIV compared with the general population in the United States, 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