{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,21]],"date-time":"2026-10-21T01:18:37Z","timestamp":1792545517967,"version":"4.5.0"},"reference-count":63,"publisher":"Oxford University Press (OUP)","issue":"11","license":[{"start":{"date-parts":[[2018,5,19]],"date-time":"2018-05-19T00:00:00Z","timestamp":1526688000000},"content-version":"vor","delay-in-days":1,"URL":"https:\/\/academic.oup.com\/journals\/pages\/open_access\/funder_policies\/chorus\/standard_publication_model"}],"funder":[{"DOI":"10.13039\/100000054","name":"National Cancer Institute","doi-asserted-by":"publisher","award":["U54\u00a0CA155435-01"],"award-info":[{"award-number":["U54\u00a0CA155435-01"]}],"id":[{"id":"10.13039\/100000054","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000054","name":"National Cancer Institute","doi-asserted-by":"crossref","award":["F31CA183125"],"award-info":[{"award-number":["F31CA183125"]}],"id":[{"id":"10.13039\/100000054","id-type":"DOI","asserted-by":"crossref"}]},{"DOI":"10.13039\/100000054","name":"National Cancer Institute","doi-asserted-by":"crossref","award":["K07CA181323"],"award-info":[{"award-number":["K07CA181323"]}],"id":[{"id":"10.13039\/100000054","id-type":"DOI","asserted-by":"crossref"}]},{"DOI":"10.13039\/100000054","name":"National Cancer Institute","doi-asserted-by":"crossref","award":["K07CA178870"],"award-info":[{"award-number":["K07CA178870"]}],"id":[{"id":"10.13039\/100000054","id-type":"DOI","asserted-by":"crossref"}]},{"DOI":"10.13039\/100000054","name":"National Cancer Institute","doi-asserted-by":"crossref","award":["3U54 CA155435-04S1"],"award-info":[{"award-number":["3U54 CA155435-04S1"]}],"id":[{"id":"10.13039\/100000054","id-type":"DOI","asserted-by":"crossref"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2018,11,1]]},"DOI":"10.1093\/jnci\/djy040","type":"journal-article","created":{"date-parts":[[2018,3,2]],"date-time":"2018-03-02T20:11:17Z","timestamp":1520021477000},"page":"1239-1247","source":"Crossref","is-referenced-by-count":64,"title":["The Effects of Metformin and Weight Loss on Biomarkers Associated With Breast Cancer Outcomes"],"prefix":"10.1093","volume":"110","author":[{"given":"Ruth E","family":"Patterson","sequence":"first","affiliation":[{"name":"Department of Family Medicine and Public Health, La Jolla, CA"},{"name":"Moores UC San Diego Cancer Center, La Jolla, CA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Catherine R","family":"Marinac","sequence":"additional","affiliation":[{"name":"Department of Epidemiology, Harvard TH Chan School of Public Health, Boston, MA"},{"name":"Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dorothy D","family":"Sears","sequence":"additional","affiliation":[{"name":"Department of Family Medicine and Public Health, La Jolla, CA"},{"name":"Department of Medicine, La Jolla, CA"},{"name":"Moores UC San Diego Cancer Center, La Jolla, CA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jacqueline","family":"Kerr","sequence":"additional","affiliation":[{"name":"Department of Family Medicine and Public Health, La Jolla, CA"},{"name":"Moores UC San Diego Cancer Center, La Jolla, CA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sheri J","family":"Hartman","sequence":"additional","affiliation":[{"name":"Department of Family Medicine and Public Health, La Jolla, CA"},{"name":"Moores UC San Diego Cancer Center, La Jolla, CA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lisa","family":"Cadmus-Bertram","sequence":"additional","affiliation":[{"name":"Department of Kinesiology, University of Wisconsin, Madison, WI"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Adriana","family":"Villase\u00f1or","sequence":"additional","affiliation":[{"name":"Department of Family Medicine and Public Health, La Jolla, CA"},{"name":"Moores UC San Diego Cancer Center, La Jolla, CA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shirley W","family":"Flatt","sequence":"additional","affiliation":[{"name":"Moores UC San Diego Cancer Center, La Jolla, CA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Suneeta","family":"Godbole","sequence":"additional","affiliation":[{"name":"UC San Diego, La Jolla, CA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hongying","family":"Li","sequence":"additional","affiliation":[{"name":"UC San Diego, La Jolla, CA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gail A","family":"Laughlin","sequence":"additional","affiliation":[{"name":"Department of Family Medicine and Public Health, La Jolla, CA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jesica","family":"Oratowski-Coleman","sequence":"additional","affiliation":[{"name":"Moores UC San Diego Cancer Center, La Jolla, CA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Barbara A","family":"Parker","sequence":"additional","affiliation":[{"name":"Department of Medicine, La Jolla, CA"},{"name":"Moores UC San Diego Cancer Center, La Jolla, CA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Loki","family":"Natarajan","sequence":"additional","affiliation":[{"name":"Department of Family Medicine and Public Health, La Jolla, CA"},{"name":"Moores UC San Diego Cancer Center, La Jolla, CA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[2018,5,18]]},"reference":[{"issue":"4","key":"key\n\t\t\t\t2018111418570180400_djy040-B1","doi-asserted-by":"crossref","first-page":"271","DOI":"10.3322\/caac.21349","article-title":"Cancer treatment and survivorship statistics, 2016","volume":"66","author":"Miller","year":"2016","journal-title":"CA Cancer J Clin."},{"key":"key\n\t\t\t\t2018111418570180400_djy040-B2","author":"National Cancer Institute"},{"issue":"7","key":"key\n\t\t\t\t2018111418570180400_djy040-B3","doi-asserted-by":"crossref","first-page":"646","DOI":"10.1200\/JCO.2015.64.7503","article-title":"Obesity and breast cancer outcomes: How much evidence is needed to change practice?","volume":"34","author":"Goodwin","year":"2016","journal-title":"J Clin Oncol."},{"issue":"12","key":"key\n\t\t\t\t2018111418570180400_djy040-B4","doi-asserted-by":"crossref","DOI":"10.1093\/jnci\/djv275","article-title":"Weight gain after breast cancer diagnosis and all-cause mortality: Systematic review and meta-analysis","volume":"107","author":"Playdon","year":"2015","journal-title":"J Natl Cancer Inst."},{"issue":"10","key":"key\n\t\t\t\t2018111418570180400_djy040-B5","doi-asserted-by":"crossref","first-page":"1901","DOI":"10.1093\/annonc\/mdu042","article-title":"Body mass index and survival in women with breast cancer-systematic literature review and meta-analysis of 82 follow-up studies","volume":"25","author":"Chan","year":"2014","journal-title":"Ann Oncol."},{"key":"key\n\t\t\t\t2018111418570180400_djy040-B6","doi-asserted-by":"crossref","first-page":"177","DOI":"10.1007\/978-3-319-16366-6_12","article-title":"Modifiable lifestyle factors and breast cancer outcomes: Current controversies and research recommendations","volume":"862","author":"Goodwin","year":"2015","journal-title":"Adv Exp Med Biol."},{"key":"key\n\t\t\t\t2018111418570180400_djy040-B7","volume-title":"Breast Cancer 2010 Report: Food, Nutrition, Physical Activity and the Prevention of Breast Cancer.","author":"World Cancer Research Fund, American Institute for Cancer Research","year":"2010"},{"issue":"7","key":"key\n\t\t\t\t2018111418570180400_djy040-B8","doi-asserted-by":"crossref","first-page":"1674","DOI":"10.2337\/dc10-0666","article-title":"Diabetes and cancer: A consensus report","volume":"33","author":"Giovannucci","year":"2010","journal-title":"Diabetes Care."},{"issue":"8","key":"key\n\t\t\t\t2018111418570180400_djy040-B9","doi-asserted-by":"crossref","first-page":"1065","DOI":"10.1007\/s10552-015-0599-z","article-title":"Associations between diabetes medication use and risk of second breast cancer events and mortality","volume":"26","author":"Calip","year":"2015","journal-title":"Cancer Causes Control."},{"issue":"5","key":"key\n\t\t\t\t2018111418570180400_djy040-B10","doi-asserted-by":"crossref","first-page":"263","DOI":"10.1055\/s-0042-100910","article-title":"Diabetes and cancer: A review of current knowledge","volume":"124","author":"Wojciechowska","year":"2016","journal-title":"Exp Clin Endocrinol Diabetes."},{"issue":"8","key":"key\n\t\t\t\t2018111418570180400_djy040-B11","doi-asserted-by":"crossref","first-page":"1915","DOI":"10.1002\/ijc.29944","article-title":"Diabetes, metformin and incidence of and death from invasive cancer in postmenopausal women: Results from the Women's Health Initiative","volume":"138","author":"Gong","year":"2016","journal-title":"Int J Cancer."},{"issue":"3","key":"key\n\t\t\t\t2018111418570180400_djy040-B12","doi-asserted-by":"crossref","first-page":"639","DOI":"10.1007\/s10549-012-2170-x","article-title":"Metformin and breast cancer risk: A meta-analysis and critical literature review","volume":"135","author":"Col","year":"2012","journal-title":"Breast Cancer Res Treat."},{"issue":"10","key":"key\n\t\t\t\t2018111418570180400_djy040-B13","doi-asserted-by":"crossref","first-page":"3018","DOI":"10.2337\/dc12-2535","article-title":"Association between metformin therapy and mortality after breast cancer: A population-based study","volume":"36","author":"Lega","year":"2013","journal-title":"Diabetes Care."},{"issue":"2","key":"key\n\t\t\t\t2018111418570180400_djy040-B14","doi-asserted-by":"crossref","first-page":"427","DOI":"10.1007\/s10549-015-3331-5","article-title":"The association between glucose-lowering drug use and mortality among breast cancer patients with type 2 diabetes","volume":"150","author":"Vissers","year":"2015","journal-title":"Breast Cancer Res Treat."},{"issue":"3","key":"key\n\t\t\t\t2018111418570180400_djy040-B15","doi-asserted-by":"crossref","first-page":"143","DOI":"10.1038\/nrendo.2013.256","article-title":"Metformin\u2014mode of action and clinical implications for diabetes and cancer","volume":"10","author":"Pernicova","year":"2014","journal-title":"Nat Rev Endocrinol."},{"issue":"7436","key":"key\n\t\t\t\t2018111418570180400_djy040-B16","doi-asserted-by":"crossref","first-page":"256","DOI":"10.1038\/nature11808","article-title":"Biguanides suppress hepatic glucagon signalling by decreasing production of cyclic AMP","volume":"494","author":"Miller","year":"2013","journal-title":"Nature."},{"issue":"2","key":"key\n\t\t\t\t2018111418570180400_djy040-B17","doi-asserted-by":"crossref","first-page":"173","DOI":"10.1007\/s11684-015-0384-0","article-title":"Metformin and metabolic diseases: A focus on hepatic aspects","volume":"9","author":"Zheng","year":"2015","journal-title":"Front Med."},{"issue":"4","key":"key\n\t\t\t\t2018111418570180400_djy040-B18","doi-asserted-by":"crossref","first-page":"279","DOI":"10.1007\/s10059-013-0169-8","article-title":"Metabolic roles of AMPK and metformin in cancer cells","volume":"36","author":"Choi","year":"2013","journal-title":"Mol Cells."},{"issue":"2","key":"key\n\t\t\t\t2018111418570180400_djy040-B19","first-page":"197","article-title":"AMP-activated protein kinase and energy balance in breast cancer","volume":"9","author":"Zhao","year":"2017","journal-title":"Am J Transl Res."},{"issue":"6","key":"key\n\t\t\t\t2018111418570180400_djy040-B20","doi-asserted-by":"crossref","first-page":"433","DOI":"10.1016\/j.clbc.2013.08.012","article-title":"Metformin decreases circulating androgen and estrogen levels in nondiabetic women with breast cancer","volume":"13","author":"Campagnoli","year":"2013","journal-title":"Clin Breast Cancer."},{"key":"key\n\t\t\t\t2018111418570180400_djy040-B21","doi-asserted-by":"crossref","first-page":"64","DOI":"10.1016\/j.cct.2015.12.009","article-title":"Recruitment strategies, design, and participant characteristics in a trial of weight-loss and metformin in breast cancer survivors","volume":"47","author":"Patterson","year":"2016","journal-title":"Contemp Clin Trials."},{"issue":"9","key":"key\n\t\t\t\t2018111418570180400_djy040-B22","doi-asserted-by":"crossref","first-page":"1997","DOI":"10.2337\/dc06-0454","article-title":"Adherence to preventive medications: Predictors and outcomes in the Diabetes Prevention Program","volume":"29","author":"Walker","year":"2006","journal-title":"Diabetes Care."},{"key":"key\n\t\t\t\t2018111418570180400_djy040-B23","volume-title":"Social Foundations of Thought and Action: A Social Cognitive Theory.","author":"Bandura","year":"1986"},{"issue":"5","key":"key\n\t\t\t\t2018111418570180400_djy040-B24","doi-asserted-by":"crossref","first-page":"373","DOI":"10.7326\/0003-4819-157-5-201209040-00475","article-title":"Screening for and management of obesity in adults: U.S. Preventive Services Task Force recommendation statement","volume":"157","author":"Moyer","year":"2012","journal-title":"Ann Intern Med."},{"issue":"8","key":"key\n\t\t\t\t2018111418570180400_djy040-B25","doi-asserted-by":"crossref","first-page":"328","DOI":"10.1016\/j.tem.2006.08.006","article-title":"Obesity and cancer risk: The role of the insulin-IGF axis","volume":"17","author":"Renehan","year":"2006","journal-title":"Trends Endocrinol Metab."},{"key":"key\n\t\t\t\t2018111418570180400_djy040-B26","doi-asserted-by":"crossref","first-page":"301","DOI":"10.1146\/annurev.med.080708.082713","article-title":"Biological mechanisms linking obesity and cancer risk: New perspectives","volume":"61","author":"Roberts","year":"2010","journal-title":"Annu Rev Med."},{"issue":"2","key":"key\n\t\t\t\t2018111418570180400_djy040-B27","doi-asserted-by":"crossref","first-page":"86","DOI":"10.1080\/13813450902878054","article-title":"Obesity related hyperinsulinaemia and hyperglycaemia and cancer development","volume":"115","author":"Becker","year":"2009","journal-title":"Arch Physiol Biochem."},{"issue":"4","key":"key\n\t\t\t\t2018111418570180400_djy040-B28","doi-asserted-by":"crossref","first-page":"956","DOI":"10.1002\/jcb.21911","article-title":"Leptin signaling in breast cancer: An overview","volume":"105","author":"Cirillo","year":"2008","journal-title":"J Cell Biochem."},{"issue":"9","key":"key\n\t\t\t\t2018111418570180400_djy040-B29","doi-asserted-by":"crossref","first-page":"1221","DOI":"10.1038\/sj.bjc.6603051","article-title":"Adiponectin and cancer: A systematic review","volume":"94","author":"Kelesidis","year":"2006","journal-title":"Br J Cancer."},{"issue":"7203","key":"key\n\t\t\t\t2018111418570180400_djy040-B30","doi-asserted-by":"crossref","first-page":"436","DOI":"10.1038\/nature07205","article-title":"Cancer-related inflammation","volume":"454","author":"Mantovani","year":"2008","journal-title":"Nature."},{"key":"key\n\t\t\t\t2018111418570180400_djy040-B31","doi-asserted-by":"crossref","first-page":"29","DOI":"10.1007\/978-1-60327-530-9_3","article-title":"Obesity provides a permissive milieu in inflammation-associated carcinogenesis: Analysis of insulin and IGF pathways","volume":"512","author":"Nunez","year":"2009","journal-title":"Methods Mol Biol."},{"issue":"1","key":"key\n\t\t\t\t2018111418570180400_djy040-B32","doi-asserted-by":"crossref","first-page":"71","DOI":"10.1080\/13813450801954303","article-title":"Obesity and cancer: Pathophysiological and biological mechanisms","volume":"114","author":"Renehan","year":"2008","journal-title":"Arch Physiol Biochem."},{"issue":"3","key":"key\n\t\t\t\t2018111418570180400_djy040-B33","doi-asserted-by":"crossref","first-page":"347","DOI":"10.1079\/BJN20041213","article-title":"Adipokines: Inflammation and the pleiotropic role of white adipose tissue","volume":"92","author":"Trayhurn","year":"2004","journal-title":"Br J Nutr."},{"issue":"6","key":"key\n\t\t\t\t2018111418570180400_djy040-B34","doi-asserted-by":"crossref","first-page":"384","DOI":"10.1093\/jnci\/djp018","article-title":"Prevention of breast cancer in postmenopausal women: Approaches to estimating and reducing risk","volume":"101","author":"Cummings","year":"2009","journal-title":"J Natl Cancer Inst."},{"issue":"1","key":"key\n\t\t\t\t2018111418570180400_djy040-B35","doi-asserted-by":"crossref","first-page":"42","DOI":"10.1200\/JCO.2002.20.1.42","article-title":"Fasting insulin and outcome in early-stage breast cancer: Results of a prospective cohort study","volume":"20","author":"Goodwin","year":"2002","journal-title":"J Clin Oncol."},{"issue":"8","key":"key\n\t\t\t\t2018111418570180400_djy040-B36","doi-asserted-by":"crossref","first-page":"606","DOI":"10.1093\/jnci\/94.8.606","article-title":"Endogenous sex hormones and breast cancer in postmenopausal women: Reanalysis of nine prospective studies","volume":"94","author":"Key","year":"2002","journal-title":"J Natl Cancer Inst."},{"issue":"21","key":"key\n\t\t\t\t2018111418570180400_djy040-B37","doi-asserted-by":"crossref","first-page":"3437","DOI":"10.1200\/JCO.2008.18.9068","article-title":"Elevated biomarkers of inflammation are associated with reduced survival among breast cancer patients","volume":"27","author":"Pierce","year":"2009","journal-title":"J Clin Oncol."},{"issue":"16","key":"key\n\t\t\t\t2018111418570180400_djy040-B38","doi-asserted-by":"crossref","first-page":"1218","DOI":"10.1093\/jnci\/djg022","article-title":"Body mass index, serum sex hormones, and breast cancer risk in postmenopausal women","volume":"95","author":"Key","year":"2003","journal-title":"J Natl Cancer Inst."},{"issue":"6","key":"key\n\t\t\t\t2018111418570180400_djy040-B39","doi-asserted-by":"crossref","first-page":"801","DOI":"10.1016\/0022-4731(82)90038-3","article-title":"Calculation of free and bound fractions of testosterone and estradiol-17 beta to human plasma proteins at body temperature","volume":"16","author":"Sodergard","year":"1982","journal-title":"J Steroid Biochem."},{"key":"key\n\t\t\t\t2018111418570180400_djy040-B40","doi-asserted-by":"crossref","DOI":"10.1093\/oso\/9780198524847.001.0001","volume-title":"Analysis of Longitudinal Data.","author":"Diggle","year":"2002"},{"issue":"3","key":"key\n\t\t\t\t2018111418570180400_djy040-B41","doi-asserted-by":"crossref","DOI":"10.1093\/jnci\/djv006","article-title":"Effect of metformin vs placebo on weight and metabolic factors in NCIC CTG MA.32","volume":"107","author":"Goodwin","year":"2015","journal-title":"J Natl Cancer Inst."},{"issue":"3","key":"key\n\t\t\t\t2018111418570180400_djy040-B42","doi-asserted-by":"crossref","first-page":"175","DOI":"10.1016\/j.clbc.2012.03.004","article-title":"Effect of different doses of metformin on serum testosterone and insulin in non-diabetic women with breast cancer: A randomized study","volume":"12","author":"Campagnoli","year":"2012","journal-title":"Clin Breast Cancer."},{"issue":"8","key":"key\n\t\t\t\t2018111418570180400_djy040-B43","doi-asserted-by":"crossref","first-page":"2853","DOI":"10.1210\/jc.2012-1233","article-title":"Endogenous sex hormone changes in postmenopausal women in the diabetes prevention program","volume":"97","author":"Kim","year":"2012","journal-title":"J Clin Endocrinol Metab."},{"key":"key\n\t\t\t\t2018111418570180400_djy040-B44","doi-asserted-by":"crossref","first-page":"120","DOI":"10.1186\/s13058-015-0633-9","article-title":"Effect of weight loss, with or without exercise, on body composition and sex hormones in postmenopausal women: The SHAPE-2 trial","volume":"17","author":"van Gemert","year":"2015","journal-title":"Breast Cancer Res."},{"issue":"8","key":"key\n\t\t\t\t2018111418570180400_djy040-B45","doi-asserted-by":"crossref","first-page":"2404","DOI":"10.2337\/diabetes.54.8.2404","article-title":"Role of insulin secretion and sensitivity in the evolution of type 2 diabetes in the diabetes prevention program: Effects of lifestyle intervention and metformin","volume":"54","author":"Kitabchi","year":"2005","journal-title":"Diabetes."},{"issue":"19","key":"key\n\t\t\t\t2018111418570180400_djy040-B46","doi-asserted-by":"crossref","first-page":"2314","DOI":"10.1200\/JCO.2011.37.9792","article-title":"Reduced-calorie dietary weight loss, exercise, and sex hormones in postmenopausal women: Randomized controlled trial","volume":"30","author":"Campbell","year":"2012","journal-title":"J Clin Oncol."},{"issue":"9","key":"key\n\t\t\t\t2018111418570180400_djy040-B47","doi-asserted-by":"crossref","first-page":"2314","DOI":"10.1158\/0008-5472.CAN-11-3092","article-title":"Effects of a caloric restriction weight loss diet and exercise on inflammatory biomarkers in overweight\/obese postmenopausal women: A randomized controlled trial","volume":"72","author":"Imayama","year":"2012","journal-title":"Cancer Res."},{"key":"key\n\t\t\t\t2018111418570180400_djy040-B48","doi-asserted-by":"crossref","first-page":"204","DOI":"10.3389\/fphys.2017.00204","article-title":"Pro-angiogenic role of insulin: From physiology to pathology","volume":"8","author":"Escudero","year":"2017","journal-title":"Front Physiol."},{"issue":"6","key":"key\n\t\t\t\t2018111418570180400_djy040-B49","doi-asserted-by":"crossref","first-page":"R225","DOI":"10.1530\/ERC-12-0203","article-title":"The cellular and molecular mechanisms by which insulin influences breast cancer risk and progression","volume":"19","author":"Rose","year":"2012","journal-title":"Endocr Relat Cancer."},{"key":"key\n\t\t\t\t2018111418570180400_djy040-B50","author":"National Cancer Institute"},{"issue":"2","key":"key\n\t\t\t\t2018111418570180400_djy040-B51","first-page":"157","article-title":"The etiology of breast cancer\u2014from epidemiology to prevention","volume":"23","author":"Kuller","year":"1995","journal-title":"Public Health Rev."},{"issue":"19","key":"key\n\t\t\t\t2018111418570180400_djy040-B52","doi-asserted-by":"crossref","first-page":"1406","DOI":"10.1093\/jnci\/djj376","article-title":"Endogenous steroid hormone concentrations and risk of breast cancer among premenopausal women","volume":"98","author":"Eliassen","year":"2006","journal-title":"J Natl Cancer Inst."},{"issue":"3","key":"key\n\t\t\t\t2018111418570180400_djy040-B53","doi-asserted-by":"crossref","first-page":"291","DOI":"10.1016\/j.maturitas.2015.06.002","article-title":"Testosterone and breast cancer prevention","volume":"82","author":"Glaser","year":"2015","journal-title":"Maturitas."},{"issue":"4","key":"key\n\t\t\t\t2018111418570180400_djy040-B54","doi-asserted-by":"crossref","first-page":"1071","DOI":"10.1677\/erc.1.01038","article-title":"Postmenopausal serum androgens, oestrogens and breast cancer risk: The European prospective investigation into cancer and nutrition","volume":"12","author":"Kaaks","year":"2005","journal-title":"Endocr Relat Cancer."},{"issue":"12","key":"key\n\t\t\t\t2018111418570180400_djy040-B55","doi-asserted-by":"crossref","first-page":"1823","DOI":"10.1200\/JCO.2005.03.7432","article-title":"Endogenous steroid hormone concentrations and risk of breast cancer: Does the association vary by a woman's predicted breast cancer risk?","volume":"24","author":"Eliassen","year":"2006","journal-title":"J Clin Oncol."},{"issue":"19","key":"key\n\t\t\t\t2018111418570180400_djy040-B56","doi-asserted-by":"crossref","first-page":"2685","DOI":"10.1200\/JCO.2006.09.0118","article-title":"Plasma testosterone and prognosis of postmenopausal breast cancer patients","volume":"25","author":"Micheli","year":"2007","journal-title":"J Clin Oncol."},{"issue":"3","key":"key\n\t\t\t\t2018111418570180400_djy040-B57","doi-asserted-by":"crossref","first-page":"614","DOI":"10.1158\/1055-9965.EPI-07-0761","article-title":"Reproductive steroid hormones and recurrence-free survival in women with a history of breast cancer","volume":"17","author":"Rock","year":"2008","journal-title":"Cancer Epidemiol Biomarkers Prev."},{"issue":"3","key":"key\n\t\t\t\t2018111418570180400_djy040-B58","doi-asserted-by":"crossref","first-page":"931","DOI":"10.1007\/s10549-013-2499-9","article-title":"Adjuvant endocrine therapy initiation and persistence in a diverse sample of patients with breast cancer","volume":"138","author":"Friese","year":"2013","journal-title":"Breast Cancer Res Treat."},{"issue":"8","key":"key\n\t\t\t\t2018111418570180400_djy040-B59","doi-asserted-by":"crossref","first-page":"1411","DOI":"10.2337\/diacare.24.8.1411","article-title":"Utilization of oral hypoglycemic agents in a drug-insured U.S. population","volume":"24","author":"Boccuzzi","year":"2001","journal-title":"Diabetes Care."},{"issue":"5","key":"key\n\t\t\t\t2018111418570180400_djy040-B60","doi-asserted-by":"crossref","first-page":"579","DOI":"10.1093\/ajcn\/74.5.579","article-title":"Long-term weight-loss maintenance: A meta-analysis of US studies","volume":"74","author":"Anderson","year":"2001","journal-title":"Am J Clin Nutr."},{"issue":"suppl 1","key":"key\n\t\t\t\t2018111418570180400_djy040-B61","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1111\/obr.12250","article-title":"Pathways from dieting to weight regain, to obesity and to the metabolic syndrome: An overview","volume":"16","author":"Dulloo","year":"2015","journal-title":"Obes Rev."},{"issue":"2","key":"key\n\t\t\t\t2018111418570180400_djy040-B62","doi-asserted-by":"crossref","first-page":"207","DOI":"10.4158\/EP161682.CS","article-title":"Consensus statement by the American Association of Clinical Endocrinologists and American College of Endocrinology on the comprehensive type 2 diabetes management algorithm - 2017 executive summary","volume":"23","author":"Garber","year":"2017","journal-title":"Endocr Pract."},{"issue":"10","key":"key\n\t\t\t\t2018111418570180400_djy040-B63","first-page":"790","article-title":"Obesity and breast cancer: Risk, outcomes, and future considerations","volume":"14","author":"Yung","year":"2016","journal-title":"Clin Adv Hematol Oncol."}],"container-title":["JNCI: Journal of the National Cancer Institute"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/academic.oup.com\/jnci\/article-pdf\/110\/11\/1239\/26555281\/djy040.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,7,2]],"date-time":"2025-07-02T08:49:28Z","timestamp":1751446168000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/jnci\/article\/110\/11\/1239\/4999668"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,5,18]]},"references-count":63,"journal-issue":{"issue":"11","published-online":{"date-parts":[[2018,5,18]]},"published-print":{"date-parts":[[2018,11,1]]}},"URL":"https:\/\/doi.org\/10.1093\/jnci\/djy040","relation":{},"ISSN":["0027-8874","1460-2105"],"issn-type":[{"value":"0027-8874","type":"print"},{"value":"1460-2105","type":"electronic"}],"subject":[],"published-other":{"date-parts":[[2018,11]]},"published":{"date-parts":[[2018,5,18]]}}}