{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,20]],"date-time":"2026-02-20T04:25:49Z","timestamp":1771561549718,"version":"3.50.1"},"reference-count":10,"publisher":"Oxford University Press (OUP)","issue":"7","license":[{"start":{"date-parts":[[2019,10,12]],"date-time":"2019-10-12T00:00:00Z","timestamp":1570838400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/journals\/pages\/open_access\/funder_policies\/chorus\/standard_publication_model"}],"funder":[{"DOI":"10.13039\/100006545","name":"National Institute on Minority Health and Health Disparities","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100006545","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100006545","name":"NIMHD","doi-asserted-by":"publisher","award":["#1R01MD010728-01"],"award-info":[{"award-number":["#1R01MD010728-01"]}],"id":[{"id":"10.13039\/100006545","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100006108","name":"NCATS","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100006108","id-type":"DOI","asserted-by":"publisher"}]},{"name":"University of Kansas for\u00a0Frontiers"},{"name":"University of Kansas Clinical and Translational Science Institute","award":["#KL2TR002367"],"award-info":[{"award-number":["#KL2TR002367"]}]},{"DOI":"10.13039\/100000097","name":"National Center for Research Resources","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100000097","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100006108","name":"National Center for Advancing Translational Sciences","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100006108","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","award":["#KL2TR001438"],"award-info":[{"award-number":["#KL2TR001438"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2020,7,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:p>Guidelines recommend using caution in co-prescribing opioids with benzodiazepines, yet, in practice, the extent of concurrent prescribing is poorly understood. Notably, no population-based studies, to our knowledge, have investigated concurrent prescribing among patients with cancer. We conducted a retrospective cohort study using data from the Surveillance, Epidemiology, and End Results (SEER) database linked with Medicare claims (2012\u20132016) for women diagnosed with breast cancer. We used modified Poisson regression to examine predictors of any concurrent prescriptions in the year post-diagnosis and Poisson regression to examine predictors of the number of overlapping days. We found that 13.0% of the 19\u2009267 women in our sample had concurrent prescriptions. Women who underwent more extensive treatment and those with previous use of opioids or benzodiazepines were at increased risk for concurrent prescriptions (adjusted risk ratio of previous benzodiazepine use vs no previous use = 15.05, 95% confidence interval = 13.19 to 17.19). Among women with concurrent prescriptions, overlap was most pronounced among low-income, rural, and Hispanic women (adjusted incidence rate ratio of Hispanic vs non-Hispanic white = 1.25, 95% confidence interval = 1.20 to 1.30). Our results highlight opportunities to reduce patients\u2019 unnecessary exposure to this combination.<\/jats:p>","DOI":"10.1093\/jnci\/djz201","type":"journal-article","created":{"date-parts":[[2019,10,9]],"date-time":"2019-10-09T19:28:38Z","timestamp":1570649318000},"page":"765-768","source":"Crossref","is-referenced-by-count":13,"title":["Concurrent Opioid and Benzodiazepine Prescriptions Among Older Women Diagnosed With Breast Cancer"],"prefix":"10.1093","volume":"112","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-0673-879X","authenticated-orcid":false,"given":"Devon K","family":"Check","sequence":"first","affiliation":[{"name":"Department of Population Health Sciences, Duke University School of Medicine, Duke Cancer Institute, Durham, NC"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Aaron N","family":"Winn","sequence":"first","affiliation":[{"name":"Department of Clinical Sciences, School of Pharmacy, Center for Advancing Population Science, Medical College of Wisconsin, Wauwatosa, WI"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nicole","family":"Fergestrom","sequence":"first","affiliation":[{"name":"Center for Advancing Population Science, Medical College of Wisconsin, Wauwatosa, WI"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Katherine E","family":"Reeder-Hayes","sequence":"first","affiliation":[{"name":"Division of Hematology and Oncology, Department of Medicine, University of North Carolina at Chapel Hill (UNC-CH) School of Medicine, UNC-CH Lineberger Comprehensive Cancer Center, Chapel Hill, NC"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0031-5988","authenticated-orcid":false,"given":"Joan M","family":"Neuner","sequence":"first","affiliation":[{"name":"Department of Medicine, Division of General Internal Medicine, Center for Advancing Population Science, Medical College of Wisconsin, Wauwatosa, WI"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Andrew W","family":"Roberts","sequence":"first","affiliation":[{"name":"Department of Population Health and Department of Anesthesiology, University of Kansas Medical Center (KUMC), KU Cancer Center, KUMC, Kansas City, KS"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"286","published-online":{"date-parts":[[2019,10,12]]},"reference":[{"issue":"27","key":"2020071308424952700_djz201-B1","doi-asserted-by":"crossref","first-page":"3325","DOI":"10.1200\/JCO.2016.68.5206","article-title":"Management of chronic pain in survivors of adult cancers: American Society of Clinical Oncology Clinical Practice Guideline","volume":"34","author":"Paice","year":"2016","journal-title":"J Clin Oncol"},{"key":"2020071308424952700_djz201-B2"},{"key":"2020071308424952700_djz201-B3"},{"issue":"10","key":"2020071308424952700_djz201-B4","doi-asserted-by":"crossref","first-page":"1685","DOI":"10.1007\/s11606-018-4463-1","article-title":"Transitions of care for postoperative opioid prescribing in previously opioid-naive patients in the USA: a retrospective review","volume":"33","author":"Klueh","year":"2018","journal-title":"J Gen Intern Med"},{"issue":"2","key":"2020071308424952700_djz201-B5","doi-asserted-by":"crossref","first-page":"164","DOI":"10.1007\/s11606-015-3470-8","article-title":"Provider patient-sharing networks and multiple-provider prescribing of benzodiazepines","volume":"31","author":"Ong","year":"2016","journal-title":"J Gen Intern Med"},{"issue":"3","key":"2020071308424952700_djz201-B6","doi-asserted-by":"crossref","first-page":"263","DOI":"10.1007\/s40264-016-0490-1","article-title":"The impact of provider networks on the co-prescriptions of interacting drugs: a claims-based analysis","volume":"40","author":"Ong","year":"2017","journal-title":"Drug Saf"},{"key":"2020071308424952700_djz201-B7","first-page":"IV3","article-title":"Overview of the SEER-Medicare data: content, research applications, and generalizability to the United States elderly population","volume":"40(8 Suppl)","author":"Warren","year":"2002","journal-title":"Med Care"},{"key":"2020071308424952700_djz201-B8","doi-asserted-by":"crossref","DOI":"10.1007\/978-1-4757-3656-4","volume-title":"AJCC Cancer Staging Manual","author":"Green","year":"2002","edition":"6th ed"},{"issue":"7","key":"2020071308424952700_djz201-B9","doi-asserted-by":"crossref","first-page":"702","DOI":"10.1093\/aje\/kwh090","article-title":"A modified Poisson regression approach to prospective studies with binary data","volume":"159","author":"Zou","year":"2004","journal-title":"Am J Epidemiol"},{"key":"2020071308424952700_djz201-B10"}],"container-title":["JNCI: Journal of the National Cancer Institute"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/academic.oup.com\/jnci\/advance-article-pdf\/doi\/10.1093\/jnci\/djz201\/32370582\/djz201.pdf","content-type":"application\/pdf","content-version":"am","intended-application":"syndication"},{"URL":"http:\/\/academic.oup.com\/jnci\/article-pdf\/112\/7\/765\/33490440\/djz201.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"http:\/\/academic.oup.com\/jnci\/article-pdf\/112\/7\/765\/33490440\/djz201.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2020,7,13]],"date-time":"2020-07-13T12:47:02Z","timestamp":1594644422000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/jnci\/article\/112\/7\/765\/5586329"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,10,12]]},"references-count":10,"journal-issue":{"issue":"7","published-online":{"date-parts":[[2019,10,12]]},"published-print":{"date-parts":[[2020,7,1]]}},"URL":"https:\/\/doi.org\/10.1093\/jnci\/djz201","relation":{},"ISSN":["0027-8874","1460-2105"],"issn-type":[{"value":"0027-8874","type":"print"},{"value":"1460-2105","type":"electronic"}],"subject":[],"published-other":{"date-parts":[[2020,7]]},"published":{"date-parts":[[2019,10,12]]}}}