{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,1]],"date-time":"2026-11-01T03:12:14Z","timestamp":1793502734253,"version":"4.5.0"},"reference-count":39,"publisher":"Oxford University Press (OUP)","issue":"6","license":[{"start":{"date-parts":[[2023,11,20]],"date-time":"2023-11-20T00:00:00Z","timestamp":1700438400000},"content-version":"vor","delay-in-days":20,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2023,10,31]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:sec>\n                  <jats:title>Background<\/jats:title>\n                  <jats:p>Adolescent and young adult cancer survivors experience mental health challenges, yet little is known about the evolution of these difficulties. This study explored mental health symptoms and utilization among long-term adolescent and young adult cancer survivors.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Methods<\/jats:title>\n                  <jats:p>Using 30\u200a432 respondents from the 2019 National Health Interview Survey, this study compared adults with a history of adolescent and young adult cancer (diagnosed when patients were between 15 and 39 years of age) to adults without adolescent and young adult cancer. Mental health symptom severity was measured using the Patient Health Questionnaire depression scale and 7-item Generalized Anxiety Disorder questionnaires. Care utilization constituted psychotherapy and mental health medication use. Inverse propensity score weights were used to balance demographics and combined with survey weights. Descriptive statistics, multivariable generalized linear models, and structural equation modeling with 2-sided tests were used for analysis.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Results<\/jats:title>\n                  <jats:p>We compared 639 adolescent and young adult survivors with 29\u200a793 controls. Survivors were, on average, 20.5\u2009years (SE\u2009=\u20090.74) past their cancer diagnosis dates. After adjusting for survey and propensity score weights, adolescent and young adult survivors reported more severe depression (incidence rate ratio\u2009=\u20091.42, 95% confidence interval [CI]\u2009=\u20091.09 to 1.84, P\u2009&amp;lt;\u2009.01) and anxiety (incidence rate ratio\u2009=\u20091.85, 95% CI\u2009=\u20091.55 to 2.21, P\u2009&amp;lt;\u2009.001). They were more likely to use psychotherapy (odds ratio\u2009=\u20091.91, 95% CI\u2009=\u20091.16 to 3.17, P\u2009&amp;lt;\u2009.05) and mental health medications (odds ratio\u2009=\u20091.89, 95% CI\u2009=\u20091.15 to 3.11, P\u2009&amp;lt;\u2009.05). Time since diagnosis was negatively associated with symptoms and utilization. Structural equation modeling demonstrated mediation of utilization effect by symptom severity.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Conclusions<\/jats:title>\n                  <jats:p>Adolescent and young adult survivors experience worse mental health in late survivorship, despite small improvements over time. We highlight the importance of survivorship care that addresses the long-term mental health needs of these survivors.<\/jats:p>\n               <\/jats:sec>","DOI":"10.1093\/jncics\/pkad098","type":"journal-article","created":{"date-parts":[[2023,11,20]],"date-time":"2023-11-20T20:34:26Z","timestamp":1700512466000},"source":"Crossref","is-referenced-by-count":17,"title":["Mental health and care utilization in survivors of adolescent and young adult cancer"],"prefix":"10.1093","volume":"7","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-5001-9699","authenticated-orcid":false,"given":"Nikita V","family":"Baclig","sequence":"first","affiliation":[{"name":"Department of Health Policy and Management, UCLA Fielding School of Public Health , Los Angeles, CA, USA"},{"name":"Division of Hematology and Oncology, Department of Medicine, David Geffen School of Medicine, University of California Los Angeles , Los Angeles, CA, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1340-6371","authenticated-orcid":false,"given":"Warren Scott","family":"Comulada","sequence":"additional","affiliation":[{"name":"Department of Health Policy and Management, UCLA Fielding School of Public Health , Los Angeles, CA, USA"},{"name":"Department of Psychiatry and Biobehavioral Sciences, David Geffen School of Medicine, University of California Los Angeles , Los Angeles, CA, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1841-4143","authenticated-orcid":false,"given":"Patricia A","family":"Ganz","sequence":"additional","affiliation":[{"name":"Department of Health Policy and Management, UCLA Fielding School of Public Health , Los Angeles, CA, USA"},{"name":"Division of Hematology and Oncology, Department of Medicine, David Geffen School of Medicine, University of California Los Angeles , Los Angeles, CA, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[2023,11,20]]},"reference":[{"issue":"5","key":"2023122122392946600_pkad098-B1","doi-asserted-by":"publisher","first-page":"235","DOI":"10.1200\/JOP.19.00075","article-title":"Overview of adolescent and young adult oncology","volume":"15","author":"Coccia","year":"2019","journal-title":"J Oncol Pract"},{"issue":"1","key":"2023122122392946600_pkad098-B2","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1002\/mpo.1257","article-title":"Cancer in older adolescents and young adults: epidemiology, diagnosis, treatment, survival, and importance of clinical trials","volume":"38","author":"Bleyer","year":"2002","journal-title":"Med Pediatr Oncol"},{"issue":"7","key":"2023122122392946600_pkad098-B3","doi-asserted-by":"publisher","first-page":"1017","DOI":"10.1002\/cncr.29871","article-title":"Biologic and clinical characteristics of adolescent and young adult cancers: acute lymphoblastic leukemia, colorectal cancer, breast cancer, melanoma, and sarcoma","volume":"122","author":"Tricoli","year":"2016","journal-title":"Cancer"},{"key":"2023122122392946600_pkad098-B4","author":"U.S. Department of Health and Human Services, National Institutes of Health, National Cancer Institute, LIVESTRONG Young Adult Alliance. 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