{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,10]],"date-time":"2026-11-10T18:33:00Z","timestamp":1794335580648,"version":"4.9.0"},"reference-count":33,"publisher":"Oxford University Press (OUP)","issue":"5","license":[{"start":{"date-parts":[[2024,8,8]],"date-time":"2024-08-08T00:00:00Z","timestamp":1723075200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/100000968","name":"American Heart Association","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100000968","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2024,9,2]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:p>The role of social determinants of health (SDOH) in controlling hypertension (HTN) in cancer patients is unknown. We hypothesize that high SDOH scores correlate with uncontrolled HTN in hypertensive cancer patients. In our prospective study, patients completed\u00a0the Protocol for Responding to &amp; Assessing Patients\u2019 Assets, Risks &amp; Experiences questionnaire. After integrating home and clinic blood pressure readings, uncontrolled HTN was defined as systolic blood pressure greater than or equal to 140\u2009mm Hg and\/or diastolic blood pressure greater than or equal to 90\u2009mm Hg. Using Cox regression, we analyzed the impact of SDOH on HTN control, adjusting for relevant factors. The study involved 318 participants (median age 66.4, median follow-up 166\u2009days, SDOH score 6.5\u2009\u00b1\u20093.2), with stress, educational insecurity, and social isolation as prevalent adverse SDOH. High SDOH scores led to 77% increased risk of uncontrolled HTN (adjusted hazards ratio = 1.77; 95% confidence interval = 1.10 to 2.83, P\u2009=\u2009.018). Urban residents with high SDOH scores were at an even greater risk. Identifying SDOH and mitigating underlying factors may help control HTN, the most typical disease process treated in all cardio-oncology clinics.<\/jats:p>","DOI":"10.1093\/jncics\/pkae064","type":"journal-article","created":{"date-parts":[[2024,8,8]],"date-time":"2024-08-08T22:32:40Z","timestamp":1723156360000},"source":"Crossref","is-referenced-by-count":4,"title":["Adverse social determinants of health elevate uncontrolled hypertension risk: a cardio-oncology prospective cohort study"],"prefix":"10.1093","volume":"8","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-0008-0779","authenticated-orcid":false,"given":"Priyanshu","family":"Nain","sequence":"first","affiliation":[{"name":"Department of Medicine, Division of Cardiology, and Vascular Biology Center, Medical College of Georgia at Augusta University , Augusta, GA, USA"},{"name":"Cardio-Oncology Program, Department of Medicine, Cardiology Division, Medical College of Georgia at Augusta University , Augusta, GA, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nickolas","family":"Stabellini","sequence":"additional","affiliation":[{"name":"Cardio-Oncology Program, Department of Medicine, Cardiology Division, Medical College of Georgia at Augusta University , Augusta, GA, USA"},{"name":"Division of Hematology and Oncology, Department of Medicine, University Hospitals\/Seidman Cancer Center, Case Western Reserve University School of Medicine , Cleveland, OH, USA"},{"name":"Faculdade Israelita de Ci\u00eancias da Sa\u00fade Albert Einstein, Hospital Israelita Albert Einstein , S\u00e3o Paulo, SP, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Omar M","family":"Makram","sequence":"additional","affiliation":[{"name":"Department of Medicine, Division of Cardiology, and Vascular Biology Center, Medical College of Georgia at Augusta University , Augusta, GA, USA"},{"name":"Cardio-Oncology Program, Department of Medicine, Cardiology Division, Medical College of Georgia at Augusta University , Augusta, GA, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Johnathan","family":"Rast","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine, Medical College of Georgia at Augusta University , Augusta, GA, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sandeep","family":"Yerraguntla","sequence":"additional","affiliation":[{"name":"Medical College of Georgia at Augusta University , Augusta, GA, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gaurav","family":"Gopu","sequence":"additional","affiliation":[{"name":"Medical College of Georgia at Augusta University , Augusta, GA, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Aditya","family":"Bhave","sequence":"additional","affiliation":[{"name":"Medical College of Georgia at Augusta University , Augusta, GA, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lakshya","family":"Seth","sequence":"additional","affiliation":[{"name":"Medical College of Georgia at Augusta University , Augusta, GA, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Vraj","family":"Patel","sequence":"additional","affiliation":[{"name":"Medical College of Georgia at Augusta University , Augusta, GA, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Stephanie","family":"Jiang","sequence":"additional","affiliation":[{"name":"Medical College of Georgia at Augusta University , Augusta, GA, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sarah","family":"Malik","sequence":"additional","affiliation":[{"name":"Medical College of Georgia at Augusta University , Augusta, GA, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ahmed","family":"Shetewi","sequence":"additional","affiliation":[{"name":"Medical College of Georgia at Augusta University , Augusta, GA, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alberto J","family":"Montero","sequence":"additional","affiliation":[{"name":"Division of Hematology and Oncology, Department of Medicine, University Hospitals\/Seidman Cancer Center, Case Western Reserve University School of Medicine , Cleveland, OH, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jennifer","family":"Cullen","sequence":"additional","affiliation":[{"name":"Cancer Population Sciences, Case Comprehensive Cancer Center, Case Western Reserve University , Cleveland, OH, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1076-0428","authenticated-orcid":false,"given":"Neeraj","family":"Agarwal","sequence":"additional","affiliation":[{"name":"Division of Medical Oncology, Department of Internal Medicine, Huntsman Cancer Institute, University of Utah , Salt Lake City, UT, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiaoling","family":"Wang","sequence":"additional","affiliation":[{"name":"Georgia Prevention Institute, Medical College of Georgia at Augusta University , Augusta, GA, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bonnie","family":"Ky","sequence":"additional","affiliation":[{"name":"Department of Biostatistics, Epidemiology, & Informatics, Perelman School of Medicine, University of Pennsylvania , Philadelphia, PA, USA"},{"name":"Division of Cardiology, Department of Medicine, Perelman School of Medicine, University of Pennsylvania , Philadelphia, PA, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4173-3449","authenticated-orcid":false,"given":"Lauren A","family":"Baldassarre","sequence":"additional","affiliation":[{"name":"Section of Cardiovascular Medicine, Department of Medicine and Department of Radiology and Biomedical Imaging, Yale University School of Medicine , New Haven, CT, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Neal L","family":"Weintraub","sequence":"additional","affiliation":[{"name":"Department of Medicine, Division of Cardiology, and Vascular Biology Center, Medical College of Georgia at Augusta University , Augusta, GA, USA"},{"name":"Cardio-Oncology Program, Department of Medicine, Cardiology Division, Medical College of Georgia at Augusta University , Augusta, GA, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ryan A","family":"Harris","sequence":"additional","affiliation":[{"name":"Georgia Prevention Institute, Medical College of Georgia at Augusta University , Augusta, GA, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0253-1174","authenticated-orcid":false,"given":"Avirup","family":"Guha","sequence":"additional","affiliation":[{"name":"Department of Medicine, Division of Cardiology, and Vascular 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