{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,23]],"date-time":"2026-08-23T17:25:30Z","timestamp":1787505930844,"version":"build-2736575974"},"reference-count":38,"publisher":"Oxford University Press (OUP)","issue":"1","license":[{"start":{"date-parts":[[2024,12,30]],"date-time":"2024-12-30T00:00:00Z","timestamp":1735516800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"funder":[{"name":"Department of Defense Center of Excellence","award":["FEDDAMD17-02-1-0473-1"],"award-info":[{"award-number":["FEDDAMD17-02-1-0473-1"]}]},{"name":"Department of Defense Center of Excellence","award":["R01 CA46332"],"award-info":[{"award-number":["R01 CA46332"]}]},{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","award":["R01CA 229811"],"award-info":[{"award-number":["R01CA 229811"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","award":["BCTR99-3152"],"award-info":[{"award-number":["BCTR99-3152"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100009634","name":"Susan G. Komen Breast Cancer Foundation","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100009634","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100001006","name":"Breast Cancer Research Foundation","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100001006","id-type":"DOI","asserted-by":"publisher"}]},{"name":"Andersen Foundation"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2025,1,3]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Benign breast disease (BBD) increases breast cancer (BC) risk progressively for women diagnosed with nonproliferative change, proliferative disease without atypia (PDWA), and atypical hyperplasia (AH). Leveraging data from 18\u00a0704 women in the Mayo BBD Cohort (1967-2013), we evaluated temporal trends in BBD diagnoses and how they have influenced associated BC risk over 4 decades.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>BC risk trends associated with BBD were evaluated using standardized incidence ratios (SIRs) and age\u2013period\u2013cohort modeling across 4 eras\u2014premammogram (1967-1981), precore needle biopsy (CNB) (1982-1992), transition to CNB (1993-2001), and CNB era (2002-2013).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>With a median follow-up of 15.8\u2009years, 9.9% of women were diagnosed with BC (invasive and\/or DCIS). From the premammogram era to the CNB era, we observed a significant increase in BC risk, rising from an SIR of 1.61 to 1.99. The proportion of proliferative BBD diagnoses (PDWA or AH) increased markedly over time (28.1%-49.7%), as did the proportion of DCIS events (11%-28%; \u03c72 \u00a0P\u2009&amp;lt;\u2009.001). Within specific BBD categories, the risk of invasive BC increased modestly.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>Absolute risk of BC within BBD categories remained stable, but the relative risk of BC after BBD increased over time due to notable increases in higher risk BBD lesions, specifically PDWA and AH. These findings illustrate how evolving screening practices have changed the risk profile of BBD and should inform management strategies for patients with BBD in modern clinical settings.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1093\/jncics\/pkae128","type":"journal-article","created":{"date-parts":[[2024,12,23]],"date-time":"2024-12-23T15:30:37Z","timestamp":1734967837000},"source":"Crossref","is-referenced-by-count":3,"title":["Changes in breast cancer risk associated with benign breast disease from 1967 to 2013"],"prefix":"10.1093","volume":"9","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-2303-4946","authenticated-orcid":false,"given":"Amy C","family":"Degnim","sequence":"first","affiliation":[{"name":"Division of Breast and Melanoma Surgical Oncology, Mayo Clinic , Rochester, MN 55905,","place":["United States"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8356-0980","authenticated-orcid":false,"given":"Karthik","family":"Ghosh","sequence":"additional","affiliation":[{"name":"General Internal Medicine, Mayo Clinic, Rochester, MN 55905,","place":["United States"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6242-5221","authenticated-orcid":false,"given":"Robert A","family":"Vierkant","sequence":"additional","affiliation":[{"name":"Clinical Trials and Biostatistics, Mayo Clinic, Jacksonville, FL 32224,","place":["United States"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8492-9102","authenticated-orcid":false,"given":"Stacey J","family":"Winham","sequence":"additional","affiliation":[{"name":"Quantitative Health Sciences, Mayo Clinic, Rochester, MN 55905,","place":["United States"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7429-7674","authenticated-orcid":false,"given":"Tanya L","family":"Hoskin","sequence":"additional","affiliation":[{"name":"Clinical Trials and Biostatistics, Mayo Clinic, Jacksonville, FL 32224,","place":["United States"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5973-0732","authenticated-orcid":false,"given":"Jodi M","family":"Carter","sequence":"additional","affiliation":[{"name":"Laboratory Medicine and Pathology, Mayo Clinic, Rochester, MN 55905,","place":["United States"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4014-2663","authenticated-orcid":false,"given":"Bryan M","family":"McCauley","sequence":"additional","affiliation":[{"name":"Clinical Trials and Biostatistics, Mayo Clinic, Jacksonville, FL 32224,","place":["United States"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Matt R","family":"Jensen","sequence":"additional","affiliation":[{"name":"Clinical Trials and Biostatistics, Mayo Clinic, Jacksonville, FL 32224,","place":["United States"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Teresa","family":"Allers","sequence":"additional","affiliation":[{"name":"Surgery Clinical Research, Mayo Clinic, Rochester, MN 55905,","place":["United States"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marlene","family":"Frost","sequence":"additional","affiliation":[{"name":"Division of Medical Oncology, Mayo Clinic, Rochester, MN 55905,","place":["United States"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Denice L","family":"Gehling","sequence":"additional","affiliation":[{"name":"Surgery Clinical Research, Mayo Clinic, Rochester, MN 55905,","place":["United States"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jessica L","family":"Fischer","sequence":"additional","affiliation":[{"name":"Surgery Clinical Research, Mayo Clinic, Rochester, MN 55905,","place":["United States"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lisa R","family":"Seymour","sequence":"additional","affiliation":[{"name":"Surgery Clinical Research, Mayo Clinic, Rochester, MN 55905,","place":["United States"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6531-8840","authenticated-orcid":false,"given":"Laura M","family":"Pacheco-Spann","sequence":"additional","affiliation":[{"name":"Clinical Trials and Biostatistics, Mayo Clinic, Jacksonville, FL 32224,","place":["United States"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6349-9126","authenticated-orcid":false,"given":"Philip S","family":"Rosenberg","sequence":"additional","affiliation":[{"name":"Biostatistics Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, MD 20892,","place":["United States"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lori A","family":"Denison","sequence":"additional","affiliation":[{"name":"Information Technology, Mayo Clinic, Rochester, MN 55905,","place":["United States"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1962-9322","authenticated-orcid":false,"given":"Celine M","family":"Vachon","sequence":"additional","affiliation":[{"name":"Quantitative Health Sciences, Mayo Clinic, Rochester, MN 55905,","place":["United States"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lynn C","family":"Hartmann","sequence":"additional","affiliation":[{"name":"Division of Medical Oncology, Mayo Clinic, Rochester, MN 55905,","place":["United States"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1962-8784","authenticated-orcid":false,"given":"Derek C","family":"Radisky","sequence":"additional","affiliation":[{"name":"Cancer Biology, Mayo Clinic, Jacksonville, FL 32224,","place":["United States"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9222-8808","authenticated-orcid":false,"given":"Mark E","family":"Sherman","sequence":"additional","affiliation":[{"name":"Quantitative Health Sciences, Mayo Clinic, Jacksonville, FL 32224,","place":["United States"]}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[2024,12,30]]},"reference":[{"key":"2025030418403208500_pkae128-B1","doi-asserted-by":"publisher","first-page":"229","DOI":"10.1056\/NEJMoa044383","article-title":"Benign breast disease and the risk of breast cancer","volume":"353","author":"Hartmann","year":"2005","journal-title":"N Engl J Med"},{"key":"2025030418403208500_pkae128-B2","doi-asserted-by":"publisher","first-page":"146","DOI":"10.1056\/NEJM198501173120303","article-title":"Risk factors for breast cancer in women with proliferative breast disease","volume":"312","author":"Dupont","year":"1985","journal-title":"N Engl J Med"},{"key":"2025030418403208500_pkae128-B3","doi-asserted-by":"publisher","first-page":"193","DOI":"10.1001\/jamasurg.2023.6382","article-title":"Benign breast disease and breast cancer risk in the percutaneous biopsy era","volume":"159","author":"Sherman","year":"2024","journal-title":"JAMA Surg"},{"key":"2025030418403208500_pkae128-B4","doi-asserted-by":"crossref","first-page":"2698","DOI":"10.1002\/1097-0142(19850601)55:11<2698::AID-CNCR2820551127>3.0.CO;2-A","article-title":"Atypical hyperplastic lesions of the female breast. A long-term follow-up study","volume":"55","author":"Page","year":"1985","journal-title":"Cancer"},{"key":"2025030418403208500_pkae128-B5","doi-asserted-by":"crossref","first-page":"467","DOI":"10.1093\/oxfordjournals.aje.a114995","article-title":"A prospective study of the development of breast cancer in 16,692 women with benign breast disease","volume":"128","author":"Carter","year":"1988","journal-title":"Am J Epidemiol"},{"key":"2025030418403208500_pkae128-B6","doi-asserted-by":"publisher","first-page":"769","DOI":"10.1093\/oxfordjournals.aje.a114594","article-title":"Breast cancer risk associated with proliferative disease, age at first birth, and a family history of breast cancer","volume":"125","author":"Dupont","year":"1987","journal-title":"Am J Epidemiol"},{"key":"2025030418403208500_pkae128-B7","doi-asserted-by":"publisher","first-page":"619","DOI":"10.1093\/oxfordjournals.aje.a116341","article-title":"Risk of breast cancer after benign breast diseases. Variation by histologic type, degree of atypia, age at biopsy, and length of follow-up","volume":"135","author":"Krieger","year":"1992","journal-title":"Am J Epidemiol"},{"key":"2025030418403208500_pkae128-B8","doi-asserted-by":"publisher","first-page":"1408","DOI":"10.1002\/1097-0142(19920315)69:6&lt;1408::aid-cncr2820690617&gt;3.0.co;2-c","article-title":"Histologic types of benign breast disease and the risk for breast cancer. The Cancer and Steroid Hormone Study Group","volume":"69","author":"McDivitt","year":"1992","journal-title":"Cancer"},{"key":"2025030418403208500_pkae128-B9","doi-asserted-by":"publisher","first-page":"821","DOI":"10.1007\/s10552-010-9508-7","article-title":"A multi-center prospective cohort study of benign breast disease and risk of subsequent breast cancer","volume":"21","author":"Kabat","year":"2010","journal-title":"Cancer Causes Control"},{"key":"2025030418403208500_pkae128-B10","doi-asserted-by":"publisher","first-page":"569","DOI":"10.1007\/s10549-014-3254-6","article-title":"Breast cancer risk associated with benign breast disease: systematic review and meta-analysis","volume":"149","author":"Dyrstad","year":"2015","journal-title":"Breast Cancer Res Treat"},{"key":"2025030418403208500_pkae128-B11","doi-asserted-by":"crossref","first-page":"941","DOI":"10.1001\/jama.1992.03480070057030","article-title":"A prospective study of benign breast disease and the risk of breast cancer","volume":"267","author":"London","year":"1992","journal-title":"JAMA"},{"key":"2025030418403208500_pkae128-B12","first-page":"621, 627","article-title":"Use of mammography\u2014United States, 1990","volume":"39","author":"Centers for Disease Control (CDC)","year":"1990","journal-title":"MMWR Morb Mortal Wkly Rep"},{"key":"2025030418403208500_pkae128-B13","first-page":"57","article-title":"Prevention. Trends in cancer screening\u2014United States, 1987 and 1992","volume":"45","author":"Centers for Disease Control","year":"1996","journal-title":"MMWR Morb Mortal Wkly Rep"},{"key":"2025030418403208500_pkae128-B14","doi-asserted-by":"publisher","first-page":"1773","DOI":"10.1056\/NEJMoa052911","article-title":"Diagnostic performance of digital versus film mammography for breast-cancer screening","volume":"353","author":"Pisano","year":"2005","journal-title":"N Engl J Med"},{"key":"2025030418403208500_pkae128-B15","doi-asserted-by":"publisher","first-page":"e2011792","DOI":"10.1001\/jamanetworkopen.2020.11792","article-title":"Screening performance of digital breast tomosynthesis vs digital mammography in community practice by patient age, screening round, and breast density","volume":"3","author":"Lowry","year":"2020","journal-title":"JAMA Netw Open"},{"key":"2025030418403208500_pkae128-B16","doi-asserted-by":"publisher","first-page":"3116","DOI":"10.1002\/cncr.23913","article-title":"The American Cancer Society guidelines for breast screening with magnetic resonance imaging: an argument for genetic testing","volume":"113","author":"Murphy","year":"2008","journal-title":"Cancer"},{"key":"2025030418403208500_pkae128-B17","doi-asserted-by":"publisher","first-page":"580","DOI":"10.7326\/0003-4819-158-8-201304160-00002","article-title":"Short-term outcomes of screening mammography using computer-aided detection: a population-based study of Medicare enrollees","volume":"158","author":"Fenton","year":"2013","journal-title":"Ann Intern Med"},{"key":"2025030418403208500_pkae128-B18","doi-asserted-by":"publisher","first-page":"103","DOI":"10.1007\/s10549-006-9305-x","article-title":"Ultrasound-guided vacuum-assisted core breast biopsy: experience with 406 cases","volume":"102","author":"Cassano","year":"2007","journal-title":"Breast Cancer Res Treat"},{"key":"2025030418403208500_pkae128-B19","doi-asserted-by":"publisher","first-page":"641","DOI":"10.1148\/radiol.2213010364","article-title":"Clinical utility of bilateral whole-breast US in the evaluation of women with dense breast tissue","volume":"221","author":"Kaplan","year":"2001","journal-title":"Radiology"},{"key":"2025030418403208500_pkae128-B20","author":"American Cancer Society"},{"key":"2025030418403208500_pkae128-B21","doi-asserted-by":"publisher","first-page":"53","DOI":"10.1056\/NEJM198601023140111","article-title":"Screening mammography\u2014potential problems on the horizon","volume":"314","author":"Hall","year":"1986","journal-title":"N Engl J Med"},{"key":"2025030418403208500_pkae128-B22","doi-asserted-by":"publisher","first-page":"1593","DOI":"10.1001\/archinte.165.14.1593","article-title":"Breast biopsy utilization: a population-based study","volume":"165","author":"Ghosh","year":"2005","journal-title":"Arch Intern Med"},{"key":"2025030418403208500_pkae128-B23","doi-asserted-by":"publisher","first-page":"3243","DOI":"10.1001\/jama.289.24.3243","article-title":"Influence of estrogen plus progestin on breast cancer and mammography in healthy postmenopausal women: the Women\u2019s Health Initiative Randomized Trial","volume":"289","author":"Chlebowski","year":"2003","journal-title":"JAMA"},{"key":"2025030418403208500_pkae128-B24","doi-asserted-by":"publisher","first-page":"3235","DOI":"10.1200\/JCO.2008.20.5179","article-title":"American Society of Clinical Oncology clinical practice guideline update on the use of pharmacologic interventions including tamoxifen, raloxifene, and aromatase inhibition for breast cancer risk reduction","volume":"27","author":"Visvanathan","year":"2009","journal-title":"J Clin Oncol"},{"key":"2025030418403208500_pkae128-B25","doi-asserted-by":"publisher","first-page":"S51","DOI":"10.1016\/j.breast.2015.07.013","article-title":"Impact of preventive therapy on the risk of breast cancer among women with benign breast disease","volume":"24(suppl 2)","author":"Cuzick","year":"2015","journal-title":"Breast"},{"key":"2025030418403208500_pkae128-B26","doi-asserted-by":"publisher","first-page":"65","DOI":"10.1023\/a:1018435205695","article-title":"A prospective study of oral contraceptive use and risk of breast cancer (Nurses\u2019 Health Study, United States)","volume":"8","author":"Hankinson","year":"1997","journal-title":"Cancer Causes Control"},{"key":"2025030418403208500_pkae128-B27","doi-asserted-by":"publisher","first-page":"794","DOI":"10.1056\/NEJMsr1606602","article-title":"Body fatness and cancer\u2014viewpoint of the IARC Working Group","volume":"375","author":"Lauby-Secretan","year":"2016","journal-title":"N Engl J Med"},{"key":"2025030418403208500_pkae128-B28","doi-asserted-by":"publisher","first-page":"1149","DOI":"10.1080\/13548506.2016.1271438","article-title":"Positive and negative mood following imaging-guided core needle breast biopsy and receipt of biopsy results","volume":"22","author":"Perlman","year":"2017","journal-title":"Psychol Health Med"},{"key":"2025030418403208500_pkae128-B29","author":"Surveillance, Epidemiology and End Results (SEER) Program","year":"2022"},{"key":"2025030418403208500_pkae128-B30","doi-asserted-by":"publisher","first-page":"695","DOI":"10.1002\/(sici)1097-0258(19990330)18:6&lt;695::aid-sim60&gt;3.0.co;2-o","article-title":"Estimation of failure probabilities in the presence of competing risks: new representations of old estimators","volume":"18","author":"Gooley","year":"1999","journal-title":"Statist Med"},{"key":"2025030418403208500_pkae128-B31","first-page":"101","article-title":"The relative survival rate: a statistical methodology","volume":"6","author":"Ederer","year":"1961","journal-title":"Natl Cancer Inst Monogr"},{"key":"2025030418403208500_pkae128-B32","doi-asserted-by":"publisher","first-page":"2296","DOI":"10.1158\/1055-9965.EPI-14-0300","article-title":"A web tool for age-period-cohort analysis of cancer incidence and mortality rates","volume":"23","author":"Rosenberg","year":"2014","journal-title":"Cancer Epidemiol Biomarkers Prev"},{"key":"2025030418403208500_pkae128-B33","doi-asserted-by":"publisher","first-page":"912","DOI":"10.2214\/AJR.20.23314","article-title":"Digital mammography has persistently increased high-grade and overall DCIS detection without altering upgrade rate","volume":"216","author":"Neal","year":"2021","journal-title":"AJR Am J Roentgenol"},{"key":"2025030418403208500_pkae128-B34","doi-asserted-by":"publisher","first-page":"411","DOI":"10.1148\/radiology.170.2.2536185","article-title":"Ductal carcinoma in situ: Mammographic findings and clinical implications","volume":"170","author":"Dershaw","year":"1989","journal-title":"Radiology"},{"key":"2025030418403208500_pkae128-B35","doi-asserted-by":"publisher","first-page":"e026797","DOI":"10.1136\/bmjopen-2018-026797","article-title":"The COMET (Comparison of Operative versus Monitoring and Endocrine Therapy) trial: a phase III randomised controlled clinical trial for low-risk ductal carcinoma in situ (DCIS)","volume":"9","author":"Hwang","year":"2019","journal-title":"BMJ Open"},{"key":"2025030418403208500_pkae128-B36","doi-asserted-by":"publisher","first-page":"1497","DOI":"10.1016\/j.ejca.2015.05.008","article-title":"Feasibility of a prospective, randomised, open-label, international multicentre, phase III, non-inferiority trial to assess the safety of active surveillance for low risk ductal carcinoma in situ\u2014the LORD study","volume":"51","author":"Elshof","year":"2015","journal-title":"Eur J Cancer"},{"key":"2025030418403208500_pkae128-B37","doi-asserted-by":"publisher","first-page":"1089","DOI":"10.1056\/NEJM199804163381601","article-title":"Ten-year risk of false positive screening mammograms and clinical breast examinations","volume":"338","author":"Elmore","year":"1998","journal-title":"N Engl J Med"},{"key":"2025030418403208500_pkae128-B38","doi-asserted-by":"publisher","first-page":"712","DOI":"10.1001\/archsurg.134.7.712","article-title":"Histological correlation of microcalcifications in breast biopsy specimens","volume":"134","author":"Johnson","year":"1999","journal-title":"Arch Surg"}],"container-title":["JNCI Cancer Spectrum"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/academic.oup.com\/jncics\/advance-article-pdf\/doi\/10.1093\/jncics\/pkae128\/61293211\/pkae128.pdf","content-type":"application\/pdf","content-version":"am","intended-application":"syndication"},{"URL":"https:\/\/academic.oup.com\/jncics\/article-pdf\/9\/1\/pkae128\/61293211\/pkae128.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/academic.oup.com\/jncics\/article-pdf\/9\/1\/pkae128\/61293211\/pkae128.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,3,4]],"date-time":"2025-03-04T15:47:17Z","timestamp":1741103237000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/jncics\/article\/doi\/10.1093\/jncics\/pkae128\/7934485"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,12,30]]},"references-count":38,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2025,1,3]]}},"URL":"https:\/\/doi.org\/10.1093\/jncics\/pkae128","relation":{},"ISSN":["2515-5091"],"issn-type":[{"value":"2515-5091","type":"electronic"}],"subject":[],"published-other":{"date-parts":[[2025,2]]},"published":{"date-parts":[[2024,12,30]]},"article-number":"pkae128"}}