{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,26]],"date-time":"2026-08-26T14:54:11Z","timestamp":1787756051750,"version":"build-2784847793"},"reference-count":23,"publisher":"Oxford University Press (OUP)","issue":"4","license":[{"start":{"date-parts":[[2025,6,10]],"date-time":"2025-06-10T00:00:00Z","timestamp":1749513600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/100000054","name":"National Cancer Institute","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100000054","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","award":["R01CA211093"],"award-info":[{"award-number":["R01CA211093"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2025,7,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:sec>\n                  <jats:title>Background<\/jats:title>\n                  <jats:p>Evidence of the success of in vitro fertilization (IVF) procedures is critical for informed decision making before and after cancer treatment. We compared IVF outcomes between women with and without cancer.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Methods<\/jats:title>\n                  <jats:p>Using data from a national IVF database\u2014the Society for Assisted Reproductive Clinic Outcomes Reporting System, linked to statewide cancer registries and birth certificates in 9 states\u2014we identified women who initiated IVF after a cancer diagnosis. Fertility preservation was defined as oocyte retrieval \u226490\u2009days after cancer diagnosis, and IVF after cancer treatment as retrieval &amp;gt;90\u2009days postdiagnosis. Number of oocytes retrieved and conception and livebirth rates were compared between these groups and a comparison group of women without cancer in couples with male factor infertility only.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Results<\/jats:title>\n                  <jats:p>Compared with retrievals for male factor infertility only (n\u2009=\u200981\u200a370), the number of oocytes retrieved was not significantly different for women who underwent retrieval for fertility preservation (n\u2009=\u20092941) but was significantly lower for women who underwent retrievals after cancer treatment (n\u2009=\u20092479) (mean difference = \u22122.99, 95% confidence interval [CI] = \u22123.40 to 2.59). Rate of conception as a function of transfer attempts and likelihood of livebirth after conception also did not significantly differ for fertility preservation (n\u2009=\u2009291) compared with male factor infertility only (n\u2009=\u200934\u200a410). Women with IVF after cancer treatment (n\u2009=\u2009672) had a lower rate of conception (hazard ratio\u2009=\u20090.70, 95% CI = 0.61 to 0.79) but a similar overall likelihood of a livebirth after conception, relative to the group with male factor infertility only.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Conclusion<\/jats:title>\n                  <jats:p>IVF outcomes may be maximized when ovarian retrieval is initiated before cancer treatment.<\/jats:p>\n               <\/jats:sec>","DOI":"10.1093\/jncics\/pkaf057","type":"journal-article","created":{"date-parts":[[2025,6,10]],"date-time":"2025-06-10T15:14:09Z","timestamp":1749568449000},"source":"Crossref","is-referenced-by-count":4,"title":["Fertility preservation and in vitro fertilization (IVF) success rates after cancer"],"prefix":"10.1093","volume":"9","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-6535-481X","authenticated-orcid":false,"given":"Chelsea","family":"Anderson","sequence":"first","affiliation":[{"name":"Center for Gastrointestinal Biology and Disease, University of North Carolina at Chapel Hill School of Medicine , Chapel Hill, NC,","place":["United States"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1413-3464","authenticated-orcid":false,"given":"Alexis C","family":"Wardell","sequence":"additional","affiliation":[{"name":"Lineberger Comprehensive Cancer Center, School of Medicine, University of North Carolina at Chapel Hill , Chapel Hill, NC,","place":["United States"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3526-3938","authenticated-orcid":false,"given":"Allison M","family":"Deal","sequence":"additional","affiliation":[{"name":"Lineberger Comprehensive Cancer Center, School of Medicine, University of North Carolina at Chapel Hill , Chapel Hill, NC,","place":["United States"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jennifer E","family":"Mersereau","sequence":"additional","affiliation":[{"name":"Shady Grove Fertility , Carolinas, Cary, NC,","place":["United States"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0859-0741","authenticated-orcid":false,"given":"Katie","family":"Cameron","sequence":"additional","affiliation":[{"name":"Division of Reproductive Endocrinology and Infertility, Department of Gynecology and Obstetrics, Johns Hopkins University School of Medicine , Baltimore, MD,","place":["United States"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Steven D","family":"Spandorfer","sequence":"additional","affiliation":[{"name":"The Center for Reproductive Medicine and Infertility, Cornell University Medical Center , New York, NY,","place":["United States"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1762-7339","authenticated-orcid":false,"given":"Valerie L","family":"Baker","sequence":"additional","affiliation":[{"name":"Division of Reproductive Endocrinology and Infertility, Department of Gynecology and Obstetrics, Johns Hopkins University School of Medicine , Baltimore, MD,","place":["United States"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0721-1375","authenticated-orcid":false,"given":"Sara","family":"Mitra","sequence":"additional","affiliation":[{"name":"Lineberger Comprehensive Cancer Center, School of Medicine, University of North Carolina at Chapel Hill , Chapel Hill, NC,","place":["United 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Epidemiology, University of North Carolina Gillings School of Global Public Health , Chapel Hill, NC,","place":["United States"]}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[2025,6,10]]},"reference":[{"key":"2025071113363535000_pkaf057-B1","first-page":"213","author":"Benedict"},{"key":"2025071113363535000_pkaf057-B2","doi-asserted-by":"crossref","first-page":"426","DOI":"10.1093\/jnci\/djx206","article-title":"Long-term safety of pregnancy following breast cancer according to estrogen receptor status","volume":"110","author":"Lambertini","year":"2018","journal-title":"J Natl Cancer Inst"},{"key":"2025071113363535000_pkaf057-B3","doi-asserted-by":"crossref","first-page":"274","DOI":"10.1007\/s11764-010-0135-9","article-title":"Fertility in patients treated for testicular cancer","volume":"4","author":"Matos","year":"2010","journal-title":"J Cancer 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