{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,12,9]],"date-time":"2025-12-09T16:31:58Z","timestamp":1765297918629,"version":"3.46.0"},"reference-count":28,"publisher":"Oxford University Press (OUP)","issue":"6","license":[{"start":{"date-parts":[[2025,10,1]],"date-time":"2025-10-01T00:00:00Z","timestamp":1759276800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"National Cancer Institute of the National Institutes of Health","award":["P01CA233432","3P01CA233432-05S1"],"award-info":[{"award-number":["P01CA233432","3P01CA233432-05S1"]}]},{"name":"California Department of Public Health pursuant to California Health and Safety Code Section","award":["103885"],"award-info":[{"award-number":["103885"]}]},{"name":"Disease Control and Prevention\u2019s (CDC) National Program of Cancer Registries","award":["5NU58DP006344"],"award-info":[{"award-number":["5NU58DP006344"]}]},{"name":"National Cancer Institute\u2019s SEER","award":["HHSN261201800032I"],"award-info":[{"award-number":["HHSN261201800032I"]}]},{"DOI":"10.13039\/100005595","name":"University of California","doi-asserted-by":"publisher","award":["HHSN261201800015I"],"award-info":[{"award-number":["HHSN261201800015I"]}],"id":[{"id":"10.13039\/100005595","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100006034","name":"University of Southern California","doi-asserted-by":"publisher","award":["HHSN261201800009I"],"award-info":[{"award-number":["HHSN261201800009I"]}],"id":[{"id":"10.13039\/100006034","id-type":"DOI","asserted-by":"publisher"}]},{"name":"National Cancer Institute\u2019s SEER Program","award":["HHSN261201800016I"],"award-info":[{"award-number":["HHSN261201800016I"]}]},{"name":"US Centers for Disease Control and Prevention\u2019s National Program of Cancer Registries","award":["NU58DP007131"],"award-info":[{"award-number":["NU58DP007131"]}]},{"name":"University of Utah and Huntsman Cancer Foundation"},{"name":"University of Utah Huntsman Cancer Institute and the Huntsman Cancer Institute Cancer Center","award":["P30 CA2014"],"award-info":[{"award-number":["P30 CA2014"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2025,11,3]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>We examined late effects clustering among adolescent and young adult (AYA; age 15-39\u2009years at diagnosis) Hodgkin lymphoma (HL) survivors and identified characteristics associated with each cluster.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>We included AYAs with HL in 2006-2018 from the California and Utah Cancer Registries linked to statewide hospitalization, emergency department, and ambulatory surgery visit data. We identified severe late effects &amp;gt;2\u2009years after cancer diagnosis in 9 late effects categories. Latent class analysis (LCA) was used to identify late effects clusters. Multinomial logistic regression models estimated adjusted associations of demographic and treatment characteristics with LCA late effect group.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>We identified 4635 AYA HL survivors with median follow-up of 8.2\u2009years and 4 late effects groups: 77.1% had a low probability of any late effect (Low Morbidity), 12.8% had high probability of Thyroid disorders, 8.0% had high probability of Cardiovascular Disease (CVD), and 2.1% had high probability of Multiple Conditions (CVD, diabetes\/pancreatic, thyroid, and renal diseases). Publicly insured AYAs were more likely than those with private insurance to be in the CVD (OR\u2009=\u20091.53, 95% CI\u2009=\u20091.18 to 1.98) and Multiple Conditions (OR\u2009=\u20092.17, 95% CI\u2009=\u20091.29 to 3.66) than the Low Morbidity group. AYAs with radiation were more likely to be in the Multiple Conditions (OR\u2009=\u20092.31, 95% CI\u2009=\u20091.41 to 3.78) and Thyroid (OR\u2009=\u20092.81, 95% CI\u2009=\u20092.20 to 3.58) groups. Hematopoietic cell transplantation was associated with Multiple Conditions (OR\u2009=\u20099.50, 95% CI\u2009=\u20095.82 to 15.50), CVD (OR\u2009=\u20093.82, 95% CI\u2009=\u20092.96 to 4.93), and Thyroid (OR\u2009=\u20092.86, 95% CI\u2009=\u20092.12 to 3.85) groups.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>While most AYA HL survivors were in the Low Morbidity group, those with public insurance or intense treatment may be at higher risk for multiple conditions.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1093\/jncics\/pkaf094","type":"journal-article","created":{"date-parts":[[2025,9,27]],"date-time":"2025-09-27T11:52:07Z","timestamp":1758973927000},"source":"Crossref","is-referenced-by-count":0,"title":["Identifying clustering in patterns of late effects among survivors of adolescent and young adult Hodgkin lymphoma"],"prefix":"10.1093","volume":"9","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-3774-5992","authenticated-orcid":false,"given":"Kellee","family":"Parker","sequence":"first","affiliation":[{"name":"Department of Pediatrics, University of Utah , Salt Lake City, UT,","place":["United States"]},{"name":"Huntsman Cancer Institute, University of Utah , Salt Lake City, UT,","place":["United States"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9454-0857","authenticated-orcid":false,"given":"Mallorie B","family":"Heneghan","sequence":"additional","affiliation":[{"name":"Department of Pediatrics, University of Utah , Salt Lake City, UT,","place":["United States"]},{"name":"Huntsman Cancer Institute, University of Utah , Salt Lake City, UT,","place":["United States"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Qian W","family":"Li","sequence":"additional","affiliation":[{"name":"University of California, Davis 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