{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,9]],"date-time":"2026-10-09T19:49:08Z","timestamp":1791575348296,"version":"4.3.4"},"reference-count":27,"publisher":"Oxford University Press (OUP)","issue":"5","license":[{"start":{"date-parts":[[2026,8,19]],"date-time":"2026-08-19T00:00:00Z","timestamp":1787097600000},"content-version":"vor","delay-in-days":1,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/100000054","name":"National Cancer Institute","doi-asserted-by":"publisher","award":["R01CA219389"],"award-info":[{"award-number":["R01CA219389"]}],"id":[{"id":"10.13039\/100000054","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2026,9,3]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>Chemotherapy-induced nausea and vomiting are among the most distressing side effects of cancer therapy. Younger age is a risk factor for chemotherapy-induced nausea and vomiting, and cancer incidence is rising among young adults ages 18-39 years. However, the comparative burden of chemotherapy-induced nausea and vomiting in young adults vs non-young adults remains insufficiently understood. This study compared acute and delayed chemotherapy-induced nausea and vomiting between young adults and non-young adults (ie, ages 40 years and older) after the first infusion of moderately or highly emetogenic chemotherapy. Of 1609 participants, 159 (10%) were young adults. Rates of guideline-consistent antiemetic prophylactic care were similar between groups (65% young adults, 71% non-young adults; P\u2009=\u2009.11). Despite this, acute nausea was more prevalent (69% vs 40%; P\u2009&amp;lt;\u2009.001) and severe (mean [SD]\u2009=\u20093.9 [2.6] vs mean = 3.0 [2.3] on 0-10 scale; P\u2009&amp;lt;\u2009.001) among young adults vs non-young adults. Similarly, delayed nausea was more prevalent (85% vs 69%; P\u2009&amp;lt;\u2009.001) and severe (mean = 4.5 [2.4] vs mean = 3.7 [2.5]; P\u2009&amp;lt;\u2009.001) among young adults. Findings may inform clinical approaches to managing chemotherapy-induced nausea and vomiting among young adults.<\/jats:p>","DOI":"10.1093\/jncics\/pkag082","type":"journal-article","created":{"date-parts":[[2026,8,12]],"date-time":"2026-08-12T11:52:20Z","timestamp":1786535540000},"source":"Crossref","is-referenced-by-count":1,"title":["Comparing chemotherapy-induced nausea and vomiting between young adult vs non-young adult cancer patients"],"prefix":"10.1093","volume":"10","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-6281-2512","authenticated-orcid":false,"given":"Laura B","family":"Oswald","sequence":"first","affiliation":[{"name":"Department of Health Outcomes and Behavior, Moffitt Cancer Center , Tampa, FL,","place":["United States"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Aasha I","family":"Hoogland","sequence":"additional","affiliation":[{"name":"Department of Health Outcomes and Behavior, Moffitt Cancer Center , Tampa, FL,","place":["United 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Behavior, Moffitt Cancer Center , Tampa, FL,","place":["United States"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Samantha","family":"Reese","sequence":"additional","affiliation":[{"name":"Department of Health Outcomes and Behavior, Moffitt Cancer Center , Tampa, FL,","place":["United States"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Paige W","family":"Lake","sequence":"additional","affiliation":[{"name":"Department of Health Outcomes and Behavior, Moffitt Cancer Center , Tampa, FL,","place":["United States"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Brian D","family":"Gonzalez","sequence":"additional","affiliation":[{"name":"Department of Health Outcomes and Behavior, Moffitt Cancer Center , Tampa, FL,","place":["United 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