{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,10]],"date-time":"2025-10-10T12:17:29Z","timestamp":1760098649080,"version":"3.41.2"},"reference-count":25,"publisher":"Oxford University Press (OUP)","issue":"4","license":[{"start":{"date-parts":[[2019,8,7]],"date-time":"2019-08-07T00:00:00Z","timestamp":1565136000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"funder":[{"name":"Genentech. Dr Killelea"},{"name":"National Comprehensive Cancer"},{"name":"Johnson & Johnson, Inc"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2019,12,1]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>The use of sentinel lymph node biopsy (SLNB) for ductal carcinoma in situ (DCIS) is controversial. Using population-cohort data, we examined whether SLNB improves long-term outcomes among patients with DCIS who underwent breast-conserving surgery. We identified 12\u2009776 women aged 67\u201394 years diagnosed during 2001\u20132013 with DCIS who underwent breast-conserving surgery from the US Surveillance, Epidemiology, and End Results-Medicare dataset, 1992 (15.6%) of whom underwent SLNB (median\u00a0follow-up: 69\u2009months). Tests of statistical significance are two-sided. Patients with and without SLNB did not differ statistically\u00a0significantly regarding treated recurrence (3.9% vs 3.7%; P = .62), ipsilateral invasive occurrence (1.4% vs 1.7%, P = .33), or breast cancer mortality (1.0% vs 0.9%, P = .86). With Mahalanobis-matching and competing-risks survival analyses, SLNB was not statistically significantly associated with treated recurrence, ipsilateral invasive occurrence, or breast cancer mortality (P\u2009\u2265\u2009.27). Our findings do not support the routine performance of SLNB for older patients with DCIS amenable to breast conservation.<\/jats:p>","DOI":"10.1093\/jncics\/pkz052","type":"journal-article","created":{"date-parts":[[2019,8,7]],"date-time":"2019-08-07T13:44:40Z","timestamp":1565185480000},"source":"Crossref","is-referenced-by-count":8,"title":["Long-Term Outcomes of Sentinel Lymph Node Biopsy for Ductal Carcinoma in Situ"],"prefix":"10.1093","volume":"3","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-1529-0819","authenticated-orcid":false,"given":"Peiyin","family":"Hung","sequence":"first","affiliation":[{"name":"Department of Health Services Policy and Management, Arnold School of Public Health, University of South Carolina, Columbia, SC"},{"name":"Department of Chronic Disease Epidemiology, Yale School of Public Health, New Haven, CT"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shi-Yi","family":"Wang","sequence":"first","affiliation":[{"name":"Cancer Outcomes, Public Policy, and Effectiveness Research (COPPER) Center, Yale Cancer Center, New Haven, CT"},{"name":"Department of Chronic Disease Epidemiology, Yale School of Public Health, New Haven, CT"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Brigid K","family":"Killelea","sequence":"first","affiliation":[{"name":"Cancer Outcomes, Public Policy, and Effectiveness Research (COPPER) Center, Yale Cancer Center, New Haven, CT"},{"name":"Department of Surgery, Yale School of Medicine, New Haven, CT"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sarah S","family":"Mougalian","sequence":"first","affiliation":[{"name":"Cancer Outcomes, Public Policy, and Effectiveness Research (COPPER) Center, Yale Cancer Center, New Haven, CT"},{"name":"Section of Medical Oncology, Department of Internal Medicine, Yale School of Medicine, New Haven, CT"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Suzanne B","family":"Evans","sequence":"first","affiliation":[{"name":"Cancer Outcomes, Public Policy, and Effectiveness Research (COPPER) Center, Yale Cancer Center, New Haven, CT"},{"name":"Department of Therapeutic Radiology, Yale School of Medicine, New Haven, CT"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tannaz","family":"Sedghi","sequence":"first","affiliation":[{"name":"Cancer Outcomes, Public Policy, and Effectiveness Research (COPPER) Center, Yale Cancer Center, New Haven, CT"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Cary P","family":"Gross","sequence":"first","affiliation":[{"name":"Cancer Outcomes, Public Policy, and Effectiveness Research (COPPER) Center, Yale Cancer Center, New Haven, CT"},{"name":"Section of General Internal Medicine, Department of Internal Medicine, Yale School of Medicine, New Haven, 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