{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,9,28]],"date-time":"2025-09-28T08:29:55Z","timestamp":1759048195512},"reference-count":38,"publisher":"Oxford University Press (OUP)","issue":"5","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J Neuropathol Exp Neurol"],"published-print":{"date-parts":[[2000,5]]},"DOI":"10.1093\/jnen\/59.5.368","type":"journal-article","created":{"date-parts":[[2016,1,11]],"date-time":"2016-01-11T23:39:44Z","timestamp":1452555584000},"page":"368-376","source":"Crossref","is-referenced-by-count":21,"title":["Role of TNF-\u03b1 in High-Dose Antigen Therapy in Experimental Autoimmune Neuritis: Inhibition of TNF-\u03b1 by Neutralizing Antibodies Reduces T-Cell Apoptosis and Prevents Liver Necrosis"],"prefix":"10.1093","volume":"59","author":[{"given":"Andreas","family":"Weishaupt","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ralf","family":"Gold","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Thomas","family":"Hartung","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Stefanie","family":"Gaupp","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Albrecht","family":"Wendel","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Wolfgang","family":"Br\u00fcck","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Klaus V.","family":"Toyka","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"286","published-online":{"date-parts":[[2000,5,1]]},"reference":[{"key":"2016011115393562000_59.5.368.1","unstructured":"Hartung HP Gold R Jung S . Local immune responses in the peripheral nervous system. In: Antel J, Birnbaum G, Hartung H-P, eds. Clinical neuroimmunology 1998;40\u201354"},{"key":"2016011115393562000_59.5.368.2","doi-asserted-by":"publisher","DOI":"10.1038\/277140a0"},{"key":"2016011115393562000_59.5.368.3","doi-asserted-by":"publisher","DOI":"10.1038\/268752a0"},{"key":"2016011115393562000_59.5.368.4","doi-asserted-by":"publisher","DOI":"10.1016\/0165-5728(95)00139-5"},{"key":"2016011115393562000_59.5.368.5","doi-asserted-by":"crossref","first-page":"1946","DOI":"10.4049\/jimmunol.133.4.1946","article-title":"A permanent rat T cell line that mediates experimental allergic neuritis in the Lewis rat in vivo","volume":"133","author":"Linington","year":"1984","journal-title":"J Immunol"},{"key":"2016011115393562000_59.5.368.6","doi-asserted-by":"crossref","first-page":"1359","DOI":"10.4049\/jimmunol.140.5.1359","article-title":"Antigen-induced suppression of the proliferation response of T cell clones","volume":"140","author":"Suzuki","year":"1988","journal-title":"J Immunol"},{"key":"2016011115393562000_59.5.368.7","doi-asserted-by":"publisher","DOI":"10.1126\/science.7509084"},{"key":"2016011115393562000_59.5.368.8","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.94.4.1338"},{"key":"2016011115393562000_59.5.368.9","doi-asserted-by":"crossref","first-page":"599","DOI":"10.1016\/S0167-5699(97)01171-7","article-title":"Systemic antigen in the treatment of T-cell-mediated autoimmune diseases","volume":"8","author":"Liblau","year":"1997","journal-title":"Immunol Today"},{"key":"2016011115393562000_59.5.368.10","doi-asserted-by":"crossref","first-page":"157","DOI":"10.1007\/978-1-4615-1891-4_18","article-title":"Amelioration of autoimmune reactions by antigen-induced apoptosis of T cells","volume":"VIII","author":"McFarland","year":"1995","journal-title":"Immunobiology of Proteins and Peptides."},{"key":"2016011115393562000_59.5.368.11","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.93.7.3031"},{"key":"2016011115393562000_59.5.368.12","doi-asserted-by":"publisher","DOI":"10.1126\/science.7533326"},{"key":"2016011115393562000_59.5.368.13","doi-asserted-by":"publisher","DOI":"10.1084\/jem.179.3.873"},{"key":"2016011115393562000_59.5.368.14","doi-asserted-by":"publisher","DOI":"10.1016\/0092-8674(93)90222-C"},{"key":"2016011115393562000_59.5.368.15","doi-asserted-by":"publisher","DOI":"10.1084\/jem.182.5.1223"},{"key":"2016011115393562000_59.5.368.16","doi-asserted-by":"crossref","first-page":"1307","DOI":"10.4049\/jimmunol.154.3.1307","article-title":"Activation of the 55 kDa TNF receptor is necessary and sufficient for TNF-induced liver failure, hepatocyte apoptosis, and nitrite release","volume":"154","author":"Leist","year":"1996","journal-title":"J Immunol"},{"key":"2016011115393562000_59.5.368.17","first-page":"817","article-title":"Tumour necrosis factor: Clinical relevance","volume":"8","author":"Jones","year":"1989","journal-title":"Cancer Surv"},{"key":"2016011115393562000_59.5.368.18","doi-asserted-by":"crossref","first-page":"1778","DOI":"10.4049\/jimmunol.153.4.1778","article-title":"Murine hepatocyte apoptosis induced in vitro and in vivo by TNF-\u03b1 requires transcriptional arrest","volume":"153","author":"Leist","year":"1994","journal-title":"J Immunol"},{"key":"2016011115393562000_59.5.368.19","doi-asserted-by":"publisher","DOI":"10.1093\/brain\/122.3.523"},{"key":"2016011115393562000_59.5.368.20","doi-asserted-by":"publisher","DOI":"10.1002\/eji.1830251027"},{"key":"2016011115393562000_59.5.368.21","doi-asserted-by":"publisher","DOI":"10.1016\/0006-2952(91)90298-J"},{"key":"2016011115393562000_59.5.368.22","doi-asserted-by":"publisher","DOI":"10.1097\/00005072-199507000-00008"},{"key":"2016011115393562000_59.5.368.23","doi-asserted-by":"publisher","DOI":"10.1016\/0014-4886(85)90129-3"},{"key":"2016011115393562000_59.5.368.24","first-page":"1039","article-title":"The role of macrophages and eicosanoids in the pathogenesis of experimental allergic neuritis","volume":"111","author":"Hartung","year":"1988","journal-title":"Serial clinical, electrophysiological, biochemical and morphological observations. Brain"},{"key":"2016011115393562000_59.5.368.25","unstructured":"Bergmeyer HU . Methods of enzymatic analysis. 3rd Ed. Verlag Chemie Weinheim, 1984;Vol. 82"},{"key":"2016011115393562000_59.5.368.26","doi-asserted-by":"publisher","DOI":"10.1084\/jem.169.1.73"},{"key":"2016011115393562000_59.5.368.27","first-page":"219","article-title":"Differentiation between cellular apoptosis and necrosis by the combined use of in situ tailing and nick translation technique","volume":"71","author":"Gold","year":"1994","journal-title":"Lab Invest"},{"key":"2016011115393562000_59.5.368.28","first-page":"162","article-title":"Homing to central nervous system vasculature by antigen-specific lymphocytes","volume":"63","author":"Cross","year":"1990","journal-title":"Lab Invest"},{"key":"2016011115393562000_59.5.368.29","doi-asserted-by":"publisher","DOI":"10.1084\/jem.185.9.1573"},{"key":"2016011115393562000_59.5.368.30","doi-asserted-by":"publisher","DOI":"10.1038\/nm0198-078"},{"key":"2016011115393562000_59.5.368.31","doi-asserted-by":"publisher","DOI":"10.1002\/(SICI)1521-4141(199902)29:02<626::AID-IMMU626>3.0.CO;2-A"},{"key":"2016011115393562000_59.5.368.32","doi-asserted-by":"publisher","DOI":"10.1016\/0165-5728(93)90178-2"},{"key":"2016011115393562000_59.5.368.33","doi-asserted-by":"publisher","DOI":"10.1084\/jem.172.4.1193"},{"key":"2016011115393562000_59.5.368.34","doi-asserted-by":"publisher","DOI":"10.1002\/eji.1830270822"},{"key":"2016011115393562000_59.5.368.35","doi-asserted-by":"publisher","DOI":"10.1002\/eji.1830240916"},{"key":"2016011115393562000_59.5.368.36","doi-asserted-by":"publisher","DOI":"10.1212\/WNL.53.3.457"},{"key":"2016011115393562000_59.5.368.37","doi-asserted-by":"crossref","first-page":"2624","DOI":"10.1002\/eji.1830261113","article-title":"Differential activation of human autoreactive T cell clones by altered peptide ligands derived from myelin basic protein peptide (87\u201399)","volume":"11","author":"Vergelli","year":"1996","journal-title":"Eur J Immunol"},{"key":"2016011115393562000_59.5.368.38","doi-asserted-by":"publisher","DOI":"10.1093\/intimm\/10.3.333"}],"container-title":["Journal of Neuropathology &amp; Experimental Neurology"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/academic.oup.com\/jnen\/article-pdf\/59\/5\/368\/8132397\/59-5-368.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,8,16]],"date-time":"2023-08-16T12:59:51Z","timestamp":1692190791000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/jnen\/article-lookup\/doi\/10.1093\/jnen\/59.5.368"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2000,5]]},"references-count":38,"journal-issue":{"issue":"5","published-online":{"date-parts":[[2000,5,1]]},"published-print":{"date-parts":[[2000,5]]}},"alternative-id":["10.1093\/jnen\/59.5.368"],"URL":"https:\/\/doi.org\/10.1093\/jnen\/59.5.368","relation":{},"ISSN":["0022-3069","1554-6578"],"issn-type":[{"value":"0022-3069","type":"print"},{"value":"1554-6578","type":"electronic"}],"subject":[],"published":{"date-parts":[[2000,5]]}}}