{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,7]],"date-time":"2026-08-07T14:37:03Z","timestamp":1786113423730,"version":"build-2736575974"},"reference-count":30,"publisher":"Oxford University Press (OUP)","issue":"8","license":[{"start":{"date-parts":[[2026,4,23]],"date-time":"2026-04-23T00:00:00Z","timestamp":1776902400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"NIA\/NIH","award":["U24 AG072122"],"award-info":[{"award-number":["U24 AG072122"]}]},{"name":"NIA-funded ADRCs","award":["P30 AG062429"],"award-info":[{"award-number":["P30 AG062429"]}]},{"name":"NIA-funded ADRCs","award":["P30 AG066468"],"award-info":[{"award-number":["P30 AG066468"]}]},{"name":"NIA-funded ADRCs","award":["P30 AG062421"],"award-info":[{"award-number":["P30 AG062421"]}]},{"name":"NIA-funded ADRCs","award":["P30 AG066509"],"award-info":[{"award-number":["P30 AG066509"]}]},{"name":"NIA-funded ADRCs","award":["P30 AG066514"],"award-info":[{"award-number":["P30 AG066514"]}]},{"name":"NIA-funded ADRCs","award":["P30 AG066530"],"award-info":[{"award-number":["P30 AG066530"]}]},{"name":"NIA-funded ADRCs","award":["P30 AG066507"],"award-info":[{"award-number":["P30 AG066507"]}]},{"name":"NIA-funded ADRCs","award":["P30 AG066444"],"award-info":[{"award-number":["P30 AG066444"]}]},{"name":"NIA-funded ADRCs","award":["P30 AG066518"],"award-info":[{"award-number":["P30 AG066518"]}]},{"name":"NIA-funded ADRCs","award":["P30 AG066512"],"award-info":[{"award-number":["P30 AG066512"]}]},{"name":"NIA-funded ADRCs","award":["P30 AG066462"],"award-info":[{"award-number":["P30 AG066462"]}]},{"name":"NIA-funded ADRCs","award":["P30 AG072979"],"award-info":[{"award-number":["P30 AG072979"]}]},{"name":"NIA-funded ADRCs","award":["P30 AG072972"],"award-info":[{"award-number":["P30 AG072972"]}]},{"name":"NIA-funded ADRCs","award":["P30 AG072976"],"award-info":[{"award-number":["P30 AG072976"]}]},{"name":"NIA-funded ADRCs","award":["P30 AG072975"],"award-info":[{"award-number":["P30 AG072975"]}]},{"name":"NIA-funded ADRCs","award":["P30 AG072978"],"award-info":[{"award-number":["P30 AG072978"]}]},{"name":"NIA-funded ADRCs","award":["P30 AG072977"],"award-info":[{"award-number":["P30 AG072977"]}]},{"name":"NIA-funded ADRCs","award":["P30 AG066519"],"award-info":[{"award-number":["P30 AG066519"]}]},{"name":"NIA-funded ADRCs","award":["P30 AG062677"],"award-info":[{"award-number":["P30 AG062677"]}]},{"name":"NIA-funded ADRCs","award":["P30 AG079280"],"award-info":[{"award-number":["P30 AG079280"]}]},{"name":"NIA-funded ADRCs","award":["P30 AG062422"],"award-info":[{"award-number":["P30 AG062422"]}]},{"name":"NIA-funded ADRCs","award":["P30 AG066511"],"award-info":[{"award-number":["P30 AG066511"]}]},{"name":"NIA-funded ADRCs","award":["P30 AG072946"],"award-info":[{"award-number":["P30 AG072946"]}]},{"name":"NIA-funded ADRCs","award":["P30 AG062715"],"award-info":[{"award-number":["P30 AG062715"]}]},{"name":"NIA-funded ADRCs","award":["P30 AG072973"],"award-info":[{"award-number":["P30 AG072973"]}]},{"name":"NIA-funded ADRCs","award":["P30 AG066506"],"award-info":[{"award-number":["P30 AG066506"]}]},{"name":"NIA-funded ADRCs","award":["P30 AG066508"],"award-info":[{"award-number":["P30 AG066508"]}]},{"name":"NIA-funded ADRCs","award":["P30 AG066515"],"award-info":[{"award-number":["P30 AG066515"]}]},{"name":"NIA-funded ADRCs","award":["P30 AG072947"],"award-info":[{"award-number":["P30 AG072947"]}]},{"name":"NIA-funded ADRCs","award":["P30 AG072931"],"award-info":[{"award-number":["P30 AG072931"]}]},{"name":"NIA-funded ADRCs","award":["P30 AG066546"],"award-info":[{"award-number":["P30 AG066546"]}]},{"name":"NIA-funded ADRCs","award":["P30 AG086401"],"award-info":[{"award-number":["P30 AG086401"]}]},{"name":"NIA-funded ADRCs","award":["P20 AG068082"],"award-info":[{"award-number":["P20 AG068082"]}]},{"name":"NIA-funded ADRCs","award":["P30 AG072958"],"award-info":[{"award-number":["P30 AG072958"]}]},{"name":"NIA-funded ADRCs","award":["P30 AG072959"],"award-info":[{"award-number":["P30 AG072959"]}]},{"DOI":"10.13039\/100000002","name":"NIH","doi-asserted-by":"publisher","award":["U19AG066567"],"award-info":[{"award-number":["U19AG066567"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000002","name":"NIH","doi-asserted-by":"publisher","award":["U19AG060909"],"award-info":[{"award-number":["U19AG060909"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000002","name":"NIH","doi-asserted-by":"publisher","award":["UM1MH130981"],"award-info":[{"award-number":["UM1MH130981"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000002","name":"NIH","doi-asserted-by":"publisher","award":["UM1MH134812"],"award-info":[{"award-number":["UM1MH134812"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000002","name":"NIH","doi-asserted-by":"publisher","award":["U24AG072458"],"award-info":[{"award-number":["U24AG072458"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000002","name":"NIH","doi-asserted-by":"publisher","award":["U24NS133949"],"award-info":[{"award-number":["U24NS133949"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000002","name":"NIH","doi-asserted-by":"publisher","award":["U24NS133945"],"award-info":[{"award-number":["U24NS133945"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000002","name":"NIH","doi-asserted-by":"publisher","award":["U24NS135651"],"award-info":[{"award-number":["U24NS135651"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000002","name":"NIH","doi-asserted-by":"publisher","award":["R24AG073137"],"award-info":[{"award-number":["R24AG073137"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000002","name":"NIH","doi-asserted-by":"publisher","award":["U01NS137500"],"award-info":[{"award-number":["U01NS137500"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000002","name":"NIH","doi-asserted-by":"publisher","award":["U01NS137484"],"award-info":[{"award-number":["U01NS137484"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000002","name":"NIH","doi-asserted-by":"publisher","award":["U01AG082350"],"award-info":[{"award-number":["U01AG082350"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000002","name":"NIH","doi-asserted-by":"publisher","award":["R01AG082730"],"award-info":[{"award-number":["R01AG082730"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000002","name":"NIH","doi-asserted-by":"publisher","award":["R01AG087226"],"award-info":[{"award-number":["R01AG087226"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000002","name":"NIH","doi-asserted-by":"publisher","award":["R01AG088656"],"award-info":[{"award-number":["R01AG088656"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000002","name":"NIH","doi-asserted-by":"publisher","award":["R01AG060942"],"award-info":[{"award-number":["R01AG060942"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2026,8,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>We examined cognitive changes associated with several neuropathologic entities, alone and in combination. We studied 808 participants from the National Alzheimer\u2019s Coordinating Center to assess associations between neuropathologic diagnoses (from autopsy) and neuropsychologic test scores (trajectories over time for 5 domains: overall cognition, episodic memory, attention, language, executive function). Neuropathologies included: Alzheimer disease neuropathologic change (ADNC), Lewy body disease (LBD), vascular brain injury (VBI), and limbic-predominant age-related TDP43 encephalopathy neuropathologic change (LATE-NC). Using linear mixed-effects models, we examined trajectories of cognitive decline for ADNC alone compared to ADNC plus LBD, VBI, or LATE-NC. We also examined differences between observed trajectories and trajectories that would be expected if the neuropathologic entities exerted their effects independently (additively). ADNC+LBD had worse decline than ADNC alone for 4 of the 5 domains with rate of decline consistent with an additive model for all 4 domains. ADNC+LATE-NC had worse decline than ADNC alone for 3 domains with rate of decline additive for only one and &amp;lt;additive for 2. ADNC+VBI had worse decline than ADNC alone for only one domain, with rate of decline &amp;lt;additive. These findings are relevant for prognostication in clinical practice and for clinical trial design.<\/jats:p>","DOI":"10.1093\/jnen\/nlag033","type":"journal-article","created":{"date-parts":[[2026,4,3]],"date-time":"2026-04-03T11:43:11Z","timestamp":1775216591000},"page":"857-867","source":"Crossref","is-referenced-by-count":0,"title":["Effects of concurrent neuropathologies with Alzheimer disease neuropathologic change on cognitive decline: Minimal impact of vascular brain injury compared with other combinations"],"prefix":"10.1093","volume":"85","author":[{"ORCID":"https:\/\/orcid.org\/0009-0000-6770-1758","authenticated-orcid":false,"given":"Sarah M","family":"Yasuda","sequence":"first","affiliation":[{"name":"Department of Epidemiology, National Alzheimer\u2019s Coordinating Center, University of Washington , Seattle, WA,","place":["United States"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Charles","family":"Mock","sequence":"additional","affiliation":[{"name":"Department of Epidemiology, National Alzheimer\u2019s Coordinating Center, University of Washington , Seattle, WA,","place":["United States"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kathryn","family":"Gauthreaux","sequence":"additional","affiliation":[{"name":"Department of Epidemiology, National Alzheimer\u2019s Coordinating Center, University of Washington , Seattle, WA,","place":["United States"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kwun C G","family":"Chan","sequence":"additional","affiliation":[{"name":"Department of Epidemiology, National Alzheimer\u2019s Coordinating Center, University of Washington , Seattle, WA,","place":["United States"]},{"name":"Department of Biostatistics, University of Washington , Seattle, WA,","place":["United States"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"C Dirk","family":"Keene","sequence":"additional","affiliation":[{"name":"Department of Laboratory Medicine and Pathology, University of Washington , Seattle, WA,","place":["United States"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jessica E","family":"Culhane","sequence":"additional","affiliation":[{"name":"Department of Epidemiology, National Alzheimer\u2019s Coordinating Center, University of Washington , Seattle, WA,","place":["United States"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yen-Chi","family":"Chen","sequence":"additional","affiliation":[{"name":"Department of Epidemiology, National Alzheimer\u2019s Coordinating Center, University of Washington , Seattle, WA,","place":["United States"]},{"name":"Department of Statistics, University of Washington , Seattle, WA,","place":["United States"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Walter","family":"Kukull","sequence":"additional","affiliation":[{"name":"Department of Neurology, Washington University School of Medicine , St. Louis, MO,","place":["United States"]}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[2026,4,23]]},"reference":[{"key":"2026080515013468400_nlag033-B1","doi-asserted-by":"crossref","first-page":"1966","DOI":"10.1002\/alz.12362","article-title":"Population estimate of people with clinical AD and mild cognitive impairment in the United States (2020\u20132060)","volume":"17","author":"Rajan","year":"2021","journal-title":"Alzheimers Dement"},{"key":"2026080515013468400_nlag033-B2","doi-asserted-by":"crossref","first-page":"171","DOI":"10.1007\/s00401-017-1717-7","article-title":"Impact of multiple pathologies on the threshold for clinically overt dementia","volume":"134","author":"Kapasi","year":"2017","journal-title":"Acta Neuropathol"},{"key":"2026080515013468400_nlag033-B3","doi-asserted-by":"crossref","first-page":"1773","DOI":"10.1212\/WNL.0000000000004567","article-title":"Mixed neuropathologies and associations with domain-specific cognitive decline","volume":"89","author":"Brenowitz","year":"2017","journal-title":"Neurology"},{"key":"2026080515013468400_nlag033-B4","doi-asserted-by":"crossref","first-page":"74","DOI":"10.1002\/ana.25123","article-title":"Person-specific contribution of neuropathologies to cognitive loss in old age","volume":"83","author":"Boyle","year":"2018","journal-title":"Ann Neurol"},{"key":"2026080515013468400_nlag033-B5","doi-asserted-by":"crossref","first-page":"314","DOI":"10.1002\/ana.26823","article-title":"Relative contributions of mixed pathologies to cognitive and functional symptoms in brain donors exposed to repetitive head impacts","volume":"95","author":"Saltiel","year":"2024","journal-title":"Ann Neurol"},{"key":"2026080515013468400_nlag033-B6","doi-asserted-by":"crossref","first-page":"58","DOI":"10.1007\/s00401-024-02716-y","article-title":"Disentangling and quantifying the relative cognitive impact of concurrent mixed neurodegenerative pathologies","volume":"147","author":"Maldonado-D\u00edaz","year":"2024","journal-title":"Acta Neuropathol"},{"key":"2026080515013468400_nlag033-B7","doi-asserted-by":"crossref","first-page":"2403","DOI":"10.1002\/alz.12516","article-title":"Neuropathological lesions and their contribution to dementia and cognitive impairment in a heterogeneous clinical population","volume":"18","author":"Godrich","year":"2022","journal-title":"Alzheimers Dement"},{"key":"2026080515013468400_nlag033-B8","doi-asserted-by":"crossref","first-page":"975","DOI":"10.1093\/jnen\/nlac093","article-title":"Symptomatic profile and cognitive performance in autopsy-confirmed limbic-predominant age-related TDP-43 encephalopathy with comorbid Alzheimer disease","volume":"81","author":"Gauthreaux","year":"2022","journal-title":"J Neuropathol Exp Neurol"},{"key":"2026080515013468400_nlag033-B9","doi-asserted-by":"crossref","first-page":"900","DOI":"10.1016\/j.jalz.2016.04.006","article-title":"Microinfarcts are common and strongly related to dementia in the oldest-old: the 90+ Study","volume":"12","author":"Corrada","year":"2016","journal-title":"Alzheimers Dement"},{"key":"2026080515013468400_nlag033-B10","doi-asserted-by":"crossref","first-page":"789","DOI":"10.1001\/jamaneurol.2015.0606","article-title":"Clinical features of Alzheimer disease with and without Lewy bodies","volume":"72","author":"Chung","year":"2015","journal-title":"JAMA Neurol"},{"key":"2026080515013468400_nlag033-B11","doi-asserted-by":"crossref","first-page":"2","DOI":"10.1093\/jnen\/nlad098","article-title":"Cognitive symptoms progress with limbic-predominant age-related TDP-43 encephalopathy stage and co-occurrence with Alzheimer disease","volume":"83","author":"Hiya","year":"2023","journal-title":"J Neuropathol Exp Neurol"},{"key":"2026080515013468400_nlag033-B12","doi-asserted-by":"crossref","first-page":"e1422","DOI":"10.1212\/WNL.0000000000200001","article-title":"Limbic-predominant age-related TDP-43 encephalopathy","volume":"98","author":"Gauthreaux","year":"2022","journal-title":"Neurology"},{"key":"2026080515013468400_nlag033-B13","doi-asserted-by":"crossref","first-page":"107255","DOI":"10.1016\/j.parkreldis.2024.107255","article-title":"The effect of amyloid and tau co-pathology on disease progression in Lewy body dementia: a systematic review","volume":"131","author":"Tan","year":"2025","journal-title":"Parkinsonism Relat Disord"},{"key":"2026080515013468400_nlag033-B14","author":"Beach","year":"2024"},{"key":"2026080515013468400_nlag033-B15","doi-asserted-by":"crossref","first-page":"158","DOI":"10.1016\/j.jalz.2018.07.222","article-title":"Vascular dysfunction\u2014the disregarded partner of Alzheimer\u2019s disease","volume":"15","author":"Sweeney","year":"2019","journal-title":"Alzheimers Dement J Alzheimers Assoc"},{"key":"2026080515013468400_nlag033-B16","doi-asserted-by":"crossref","first-page":"761","DOI":"10.1093\/brain\/awu393","article-title":"Vascular and amyloid pathologies are independent predictors of cognitive decline in normal elderly","volume":"138","author":"Vemuri","year":"2015","journal-title":"Brain"},{"key":"2026080515013468400_nlag033-B17","doi-asserted-by":"crossref","first-page":"3005","DOI":"10.1093\/brain\/aws234","article-title":"Cognitive impairment, decline and fluctuations in older community-dwelling subjects with Lewy bodies","volume":"135","author":"Schneider","year":"2012","journal-title":"Brain"},{"key":"2026080515013468400_nlag033-B18","doi-asserted-by":"crossref","first-page":"1503","DOI":"10.1093\/brain\/awz099","article-title":"Limbic-predominant age-related TDP-43 encephalopathy (LATE): consensus working group report","volume":"142","author":"Nelson","year":"2019","journal-title":"Brain"},{"key":"2026080515013468400_nlag033-B19","first-page":"270","article-title":"The National Alzheimer\u2019s Coordinating Center (NACC) Database: an Alzheimer disease database","volume":"18","author":"Beekly","year":"2004","journal-title":"Alzheimer Dis Assoc Disord"},{"key":"2026080515013468400_nlag033-B20","doi-asserted-by":"crossref","first-page":"210","DOI":"10.1097\/01.wad.0000213865.09806.92","article-title":"The Uniform Data Set (UDS): clinical and cognitive variables and descriptive data from Alzheimer Disease Centers","volume":"20","author":"Morris","year":"2006","journal-title":"Alzheimer Dis Assoc Disord"},{"key":"2026080515013468400_nlag033-B21","doi-asserted-by":"crossref","first-page":"249","DOI":"10.1097\/WAD.0b013e318142774e","article-title":"The National Alzheimer\u2019s Coordinating Center (NACC) database: the Uniform Data Set","volume":"21","author":"Beekly","year":"2007","journal-title":"Alzheimer Dis Assoc Disord"},{"key":"2026080515013468400_nlag033-B22","doi-asserted-by":"crossref","first-page":"351","DOI":"10.1097\/WAD.0000000000000279","article-title":"Version 3 of the National Alzheimer\u2019s Coordinating Center\u2019s Uniform Data Set","volume":"32","author":"Besser","year":"2018","journal-title":"Alzheimer Dis Assoc Disord"},{"key":"2026080515013468400_nlag033-B23","doi-asserted-by":"crossref","first-page":"717","DOI":"10.1093\/jnen\/nly049","article-title":"The revised National Alzheimer\u2019s Coordinating Center\u2019s Neuropathology Form\u2014available data and new analyses","volume":"77","author":"Besser","year":"2018","journal-title":"J Neuropathol Exp Neurol"},{"key":"2026080515013468400_nlag033-B24","year":"2025"},{"key":"2026080515013468400_nlag033-B25","doi-asserted-by":"crossref","first-page":"128","DOI":"10.1097\/WAD.0b013e3181ffa76d","article-title":"Factor structure of the National Alzheimer\u2019s Coordinating Centers uniform dataset neuropsychological battery: an evaluation of invariance between and within groups over time","volume":"25","author":"Hayden","year":"2011","journal-title":"Alzheimer Dis Assoc Disord"},{"key":"2026080515013468400_nlag033-B26","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.jalz.2011.10.007","article-title":"National Institute on Aging\u2013Alzheimer\u2019s Association guidelines for the neuropathologic assessment of Alzheimer\u2019s disease","volume":"8","author":"Hyman","year":"2012","journal-title":"Alzheimers Dement"},{"key":"2026080515013468400_nlag033-B27","doi-asserted-by":"crossref","first-page":"e12923","DOI":"10.1111\/nan.12923","article-title":"Insights into the pathological basis of dementia from population-based neuropathology studies","volume":"49","author":"Wharton","year":"2023","journal-title":"Neuropathol Appl Neurobiol"},{"key":"2026080515013468400_nlag033-B28","doi-asserted-by":"crossref","first-page":"187","DOI":"10.3233\/JAD-180965","article-title":"Vascular burden score impacts cognition independent of amyloid PET and MRI measures of Alzheimer\u2019s disease and vascular brain injury","volume":"68","author":"DeCarli","year":"2019","journal-title":"J Alzheimers Dis"},{"key":"2026080515013468400_nlag033-B29","doi-asserted-by":"crossref","first-page":"1005","DOI":"10.3233\/JAD-200339","article-title":"The contribution of vascular pathology toward cognitive impairment in older individuals with intermediate Braak stage tau pathology","volume":"77","author":"Robinson","year":"2020","journal-title":"J Alzheimers Dis"},{"key":"2026080515013468400_nlag033-B30","doi-asserted-by":"crossref","first-page":"607","DOI":"10.1002\/ana.26447","article-title":"Associations of vascular risk and amyloid burden with subsequent dementia","volume":"92","author":"Gottesman","year":"2022","journal-title":"Ann Neurol"}],"container-title":["Journal of Neuropathology &amp; Experimental Neurology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/academic.oup.com\/jnen\/article-pdf\/85\/8\/857\/68143808\/nlag033.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/academic.oup.com\/jnen\/article-pdf\/85\/8\/857\/68143808\/nlag033.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,8,5]],"date-time":"2026-08-05T19:01:47Z","timestamp":1785956507000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/jnen\/article\/85\/8\/857\/8661470"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,4,23]]},"references-count":30,"journal-issue":{"issue":"8","published-online":{"date-parts":[[2026,4,23]]},"published-print":{"date-parts":[[2026,8,1]]}},"URL":"https:\/\/doi.org\/10.1093\/jnen\/nlag033","relation":{},"ISSN":["0022-3069","1554-6578"],"issn-type":[{"value":"0022-3069","type":"print"},{"value":"1554-6578","type":"electronic"}],"subject":[],"published-other":{"date-parts":[[2026,8]]},"published":{"date-parts":[[2026,4,23]]}}}