{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,10]],"date-time":"2025-10-10T07:26:19Z","timestamp":1760081179348},"reference-count":15,"publisher":"Oxford University Press (OUP)","issue":"12","license":[{"start":{"date-parts":[[2019,10,11]],"date-time":"2019-10-11T00:00:00Z","timestamp":1570752000000},"content-version":"vor","delay-in-days":23,"URL":"https:\/\/academic.oup.com\/journals\/pages\/open_access\/funder_policies\/chorus\/standard_publication_model"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2019,12,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:p>Dural extranodal marginal zone lymphoma of mucosa-associated lymphoid tissue (MALT lymphoma) is a rare entity without an associated recurrent genetic abnormality. Only one case has been described in a woman with history of breast carcinoma without a known genetic predisposition. Here, we report a case of a 56-year-old woman heterozygous for XRCC2 mutation with a history of Graves\u2019 disease and bilateral breast carcinomas, who was found to have a diffusely infiltrative extra-axial mass in the high parietal convexity with infiltration into the adjacent superior sagittal sinus. The morphologic, immunophenotypic, and molecular findings were diagnostic of MALT lymphoma. Staging bone marrow demonstrated involvement by the neoplasm. Although the study was limited to only the clinically significant laboratory evaluation, it may serve as an important addition to the current knowledge of the pathogenic potential of a loss of function mutation in this rarely reported cancer predisposition gene.<\/jats:p>","DOI":"10.1093\/jnen\/nlz092","type":"journal-article","created":{"date-parts":[[2019,10,11]],"date-time":"2019-10-11T14:06:28Z","timestamp":1570802788000},"page":"1174-1177","source":"Crossref","is-referenced-by-count":3,"title":["Dural Extranodal Marginal Zone Lymphoma in an XRCC2 Mutation Carrier"],"prefix":"10.1093","volume":"78","author":[{"given":"Kristina","family":"Gvozdjan","sequence":"first","affiliation":[{"name":"Department of Pathology"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Brad E","family":"Zacharia","sequence":"additional","affiliation":[{"name":"Department of Pathology"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Michael G","family":"Bayerl","sequence":"additional","affiliation":[{"name":"Department of Pathology"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Adeola","family":"Tomi-Olugbodi","sequence":"additional","affiliation":[{"name":"Department of Pathology"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Cinda","family":"Boyer","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery, Pennsylvania State University, Penn State Milton S. Hershey Medical Center, Hershey, Pennsylvania"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Charles S","family":"Specht","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery, Pennsylvania State University, Penn State Milton S. Hershey Medical Center, Hershey, Pennsylvania"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"286","published-online":{"date-parts":[[2019,9,18]]},"reference":[{"key":"2019112008501831500_nlz092-B1","first-page":"272","volume-title":"World Health Organization Classification of Tumours of the Central Nervous System","author":"Deckert","year":"2016"},{"key":"2019112008501831500_nlz092-B2","doi-asserted-by":"crossref","first-page":"326","DOI":"10.1200\/JCO.2007.14.0236","article-title":"Primary dural marginal zone lymphoma in a woman with inflammatory breast cancer","volume":"26","author":"Ancheta","year":"2008","journal-title":"J Clin Oncol"},{"key":"2019112008501831500_nlz092-B3","doi-asserted-by":"crossref","first-page":"2609","DOI":"10.1016\/j.humpath.2013.04.016","article-title":"Marginal zone B-cell lymphoma involving a longstanding fibrous meningioma: An initial manifestation of systemic disease","volume":"44","author":"Martin","year":"2013","journal-title":"Hum Pathol"},{"key":"2019112008501831500_nlz092-B4","doi-asserted-by":"crossref","first-page":"e10","DOI":"10.4081\/hr.2010.e10","article-title":"Dural MALT lymphoma with disseminated disease","volume":"2","author":"Matmati","year":"2010","journal-title":"Hematol Rep"},{"key":"2019112008501831500_nlz092-B5","doi-asserted-by":"crossref","first-page":"672","DOI":"10.1136\/jmedgenet-2016-103847","article-title":"Complementation of hypersensitivity to DNA interstrand crosslinking agents demonstrates that XRCC2 is a Fanconi anaemia gene","volume":"53","author":"Park","year":"2016","journal-title":"J Med Genet"},{"key":"2019112008501831500_nlz092-B6","doi-asserted-by":"crossref","first-page":"734","DOI":"10.1016\/j.ajhg.2012.02.027","article-title":"Rare mutations in XRCC2 increase the risk of breast cancer","volume":"90","author":"Park","year":"2012","journal-title":"Am J Hum Genet"},{"key":"2019112008501831500_nlz092-B7","volume-title":"Genomic Data Commons Data Portal [Database Online]","year":"2018"},{"key":"2019112008501831500_nlz092-B8","first-page":"259","volume-title":"World Health Organization Classification of Tumours of Haematopoietic and Lymphoid Tissues","author":"Cook","year":"2017"},{"key":"2019112008501831500_nlz092-B9","doi-asserted-by":"crossref","first-page":"447","DOI":"10.1038\/nri3700","article-title":"Ectopic lymphoid-like structures in infection, cancer and autoimmunity","volume":"14","author":"Pitzalis","year":"2014","journal-title":"Nat Rev Immunol"},{"key":"2019112008501831500_nlz092-B10","doi-asserted-by":"crossref","first-page":"49","DOI":"10.1016\/j.semcancer.2016.07.003","article-title":"MALT lymphoma: A paradigm of NF-\u03baB dysregulation","volume":"39","author":"Du","year":"2016","journal-title":"Semin Cancer Biol"},{"key":"2019112008501831500_nlz092-B11","doi-asserted-by":"crossref","first-page":"4299","DOI":"10.1128\/IAI.00477-13","article-title":"Deciphering the contribution of human meningothelial cells to the inflammatory and antimicrobial response at the meninges","volume":"81","author":"Royer","year":"2013","journal-title":"Infect Immun"},{"key":"2019112008501831500_nlz092-B12","doi-asserted-by":"crossref","first-page":"578","DOI":"10.3389\/fimmu.2016.00578","article-title":"Increased toll-like receptors activity and TLR ligands in patients with autoimmune thyroid diseases","volume":"7","author":"Peng","year":"2016","journal-title":"Front Immunol"},{"key":"2019112008501831500_nlz092-B13","first-page":"1752s","article-title":"BRCA1, BRCA2, and Rad51 operate in a common DNA damage response pathway","volume":"59","author":"Chen","year":"1999","journal-title":"Cancer Res"},{"key":"2019112008501831500_nlz092-B14","doi-asserted-by":"crossref","first-page":"26333","DOI":"10.1074\/jbc.M303076200","article-title":"BRCA1 augments transcription by the NF-kappaB transcription factor by binding to the Rel domain of the p65\/RelA subunit","volume":"278","author":"Benezra","year":"2003","journal-title":"J Biol Chem"},{"key":"2019112008501831500_nlz092-B15","doi-asserted-by":"crossref","first-page":"1729","DOI":"10.1084\/jem.20122842","article-title":"DNA repair genes are selectively mutated in diffuse large B cell lymphomas","volume":"210","author":"de Miranda","year":"2013","journal-title":"J Exp Med"}],"container-title":["Journal of Neuropathology &amp; 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