{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,29]],"date-time":"2026-07-29T19:27:18Z","timestamp":1785353238845,"version":"3.55.0"},"reference-count":42,"publisher":"Oxford University Press (OUP)","issue":"1","license":[{"start":{"date-parts":[[2024,4,29]],"date-time":"2024-04-29T00:00:00Z","timestamp":1714348800000},"content-version":"vor","delay-in-days":119,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"funder":[{"name":"Akita Prefecture Technology Innovation Creation and Utilisation Promotion Project-The Industry-Academic Government Collaboration Booster Project"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2024,1,4]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:sec>\n                  <jats:title>Objectives<\/jats:title>\n                  <jats:p>Despite the recent increase in infertility and perinatal complications, preconception care is not commonly available in Japan. Working women are considered to have the greatest need for preconception care, as increasingly they marry and have children later in life. This study aimed to assess the feasibility and effectiveness of preconception check-ups in the workplace.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Methods<\/jats:title>\n                  <jats:p>We provided 51 female employees aged 18-39\u00a0years with free preconception check-ups, including additional blood tests and an online medical questionnaire, during mandatory health check-ups at their workplace. A doctor provided online counseling based on the check-up results. We assessed fertility knowledge using the Cardiff Fertility Knowledge Scale (CFKS-J) and childbearing desire pre- and postintervention.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Results<\/jats:title>\n                  <jats:p>Preconception check-ups revealed various potential risk factors for future pregnancies, including underweight (12%), obesity (20%), Chlamydia trachomatis IgG antibody positivity (22%), low rubella IgG antibody levels (47%), iron deficiency (12%), and 25-hydroxyvitamin D levels &amp;lt;30\u00a0ng\/mL (98%). Postintervention, the participants reported high satisfaction with the check-ups and significantly advanced their reproductive plans (P\u2009=\u2009.008). Furthermore, 95% of the participants indicated an intention to seek medical attention or make lifestyle changes. The postintervention CFKS-J score (mean [SD]) was higher than the preintervention score (71.7 [19.3] vs 63.0 [22.0]; P\u2009=\u2009.006).<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Conclusions<\/jats:title>\n                  <jats:p>We developed a preconception check-up package that can be integrated into workplace health examinations, complemented by tailored counseling. This novel check-up package is a feasible and effective approach for improving preconception health and fertility awareness.<\/jats:p>\n               <\/jats:sec>","DOI":"10.1093\/joccuh\/uiae021","type":"journal-article","created":{"date-parts":[[2024,4,29]],"date-time":"2024-04-29T21:31:40Z","timestamp":1714426300000},"source":"Crossref","is-referenced-by-count":2,"title":["Feasibility and effectiveness of preconception check-ups at workplaces in Japan"],"prefix":"10.1093","volume":"66","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-8609-484X","authenticated-orcid":false,"given":"Akiko","family":"Fujishima","sequence":"first","affiliation":[{"name":"Akita University Graduate School of Medicine Department of Obstetrics and Gynaecology, , 1-1-1, Hondo, Akita-shi, Akita 010-8543, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eri","family":"Maeda","sequence":"additional","affiliation":[{"name":"Hokkaido University Department of Public Health, Faculty of Medicine, , Kita 15, Nishi 7, Kita-ku, Sapporo, Hokkaido 060-8638, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Koki","family":"Sato","sequence":"additional","affiliation":[{"name":"Specified Non-profit Corporation FORECIA , Yamani Building 6F, 2-2-23, Nakadori, Akita-shi, Akita 010-0001, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hidekazu","family":"Saito","sequence":"additional","affiliation":[{"name":"Umegaoka Women\u2019s Clinic , Tokyo, 1-33-3, Umegaoka, Setagaya-ku, Tokyo 154-0022, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chihiro","family":"Ozeki","sequence":"additional","affiliation":[{"name":"Akita University School of Medicine , Department of Medicine, 1-1-1, Hondo, Akita-shi, Akita 010-8543, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yukihiro","family":"Terada","sequence":"additional","affiliation":[{"name":"Akita University Graduate School of Medicine Department of Obstetrics and Gynaecology, , 1-1-1, Hondo, Akita-shi, Akita 010-8543, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[2024,4,29]]},"reference":[{"issue":"3","key":"2024071808420048900_ref1","doi-asserted-by":"crossref","first-page":"633","DOI":"10.1016\/j.fertnstert.2013.12.032","article-title":"Female age-related fertility decline. 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Pregnancy at age 35 years or older: ACOG obstetric care consensus No. 11","volume":"140","year":"2022","journal-title":"Obstet Gynecol"},{"key":"2024071808420048900_ref3","author":"National Institute of Population and Social Security Research"},{"key":"2024071808420048900_ref4","author":"Minister of Health, Labour and Welfare","year":"2017"},{"issue":"11","key":"2024071808420048900_ref5","doi-asserted-by":"crossref","first-page":"1255","DOI":"10.3111\/13696998.2013.830974","article-title":"Burden of menstrual symptoms in Japanese women: results from a survey-based study","volume":"16","author":"Tanaka","year":"2013","journal-title":"J Med Econ"},{"key":"2024071808420048900_ref6","author":"Centers for Disease Control and Prevention","year":"2023"},{"issue":"10132","key":"2024071808420048900_ref7","doi-asserted-by":"crossref","first-page":"1830","DOI":"10.1016\/S0140-6736(18)30311-8","article-title":"Before the beginning: nutrition and lifestyle in the preconception period and its importance for future health","volume":"391","author":"Stephenson","year":"2018","journal-title":"Lancet"},{"issue":"1","key":"2024071808420048900_ref8","doi-asserted-by":"crossref","first-page":"133","DOI":"10.1097\/AOG.0000000000000591","article-title":"Risk of adverse pregnancy outcomes by prepregnancy body mass index: a population-based study to inform prepregnancy weight loss counselling","volume":"125","author":"Schummers","year":"2015","journal-title":"Obstet Gynecol"},{"issue":"12","key":"2024071808420048900_ref9","article-title":"Effects and safety of periconceptional oral folate supplementation for preventing birth defects","volume":"2015","author":"De-Regil","year":"2015","journal-title":"Cochrane Database Syst Rev"},{"key":"2024071808420048900_ref10","author":"World Health Organization","year":"2018"},{"issue":"RR06","key":"2024071808420048900_ref11","first-page":"1","article-title":"Recommendations to improve preconception health and health care\u2014United States. 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