{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,20]],"date-time":"2026-08-20T14:36:19Z","timestamp":1787236579773,"version":"build-2736575974"},"reference-count":22,"publisher":"Oxford University Press (OUP)","issue":"4","license":[{"start":{"date-parts":[[2026,5,1]],"date-time":"2026-05-01T00:00:00Z","timestamp":1777593600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/pages\/standard-publication-reuse-rights"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2026,8,20]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>It has been over 60\u2005years since the first kidney transplant in Ireland was carried out in 1964. We examined the Irish cohort of individuals with allografts functioning for more than 40\u2005years. We sought to describe the features of these patients and identify clinical factors associated with ultra-long-term allograft survival.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>This retrospective analysis of the Irish National Kidney Transplant Registry included kidney transplants performed in Ireland between January 1st, 1970, and March 31st, 1983. Follow-up analysis was until March 31st, 2023.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>There were 428 transplants in 394 patients. Longitudinal data were available for 390 (98.9%) patients. Thirty-three (33\/428, 7.7%) kidney transplant grafts survived for 40\u2005years or more, with 25 grafts functioning at date of analysis. Multivariable analysis identified transplant type\u2014living donor versus deceased donor (odds ratio [OR] 3.51, confidence interval [CI] 1.17\u201311.1, P = .027) as significantly associated with long-term graft survival. The median serum creatinine of patients with surviving transplants was 107\u2005\u00b5mol\/L (range 66\u2013322\u2005\u00b5mol\/L). Non-melanoma skin cancer was common, affecting 22\/33 (67%) patients.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>For ultra-long survivors, graft function is excellent if patients are maintained on low-level immunosuppression. Living donor transplantation, but not donor or recipient age or sex, was associated with improved graft survival.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1093\/joneph\/aajag020","type":"journal-article","created":{"date-parts":[[2026,1,21]],"date-time":"2026-01-21T12:39:35Z","timestamp":1768999175000},"page":"834-841","source":"Crossref","is-referenced-by-count":0,"title":["Ultra-long survivors of kidney transplantation: forty years and more of graft function"],"prefix":"10.1093","volume":"39","author":[{"ORCID":"https:\/\/orcid.org\/0009-0004-8791-4290","authenticated-orcid":false,"given":"Michelle","family":"Madden","sequence":"first","affiliation":[{"name":"Department of Transplant, Urology, and Nephrology, Beaumont Hospital , Dublin ,","place":["Ireland"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gavin","family":"Comerford","sequence":"additional","affiliation":[{"name":"Department of Transplant, Urology, and Nephrology, Beaumont Hospital , Dublin 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