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Herein we review the occurrence, morphology, and consequences of stenotic glomerulotubular necks, and propose future investigations.<\/jats:p>","DOI":"10.1093\/joneph\/aajag165","type":"journal-article","created":{"date-parts":[[2026,6,16]],"date-time":"2026-06-16T12:19:39Z","timestamp":1781612379000},"source":"Crossref","is-referenced-by-count":0,"title":["Stenosis of the glomerulotubular neck with chronic kidney disease"],"prefix":"10.1093","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-4299-2290","authenticated-orcid":false,"given":"Eric P","family":"Cohen","sequence":"first","affiliation":[{"name":"Nephrology Division, Manhattan VAMC, New York University School of Medicine , New York, NY ,","place":["United States"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ian W","family":"Gibson","sequence":"additional","affiliation":[{"name":"Department of Pathology, MS-336C Electron Microscopy Lab, Health Sciences Centre, University of Manitoba , Winnipeg, MB ,","place":["Canada"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9157-5405","authenticated-orcid":false,"given":"Aleksandar","family":"Denic","sequence":"additional","affiliation":[{"name":"Division of Nephrology and Hypertension, Mayo Clinic , Rochester, MN ,","place":["United States"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8512-9238","authenticated-orcid":false,"given":"Chetan","family":"Poudel","sequence":"additional","affiliation":[{"name":"Department of Medicine, Indiana University School of Medicine , Indianapolis, IN ,","place":["United States"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andrew D","family":"Rule","sequence":"additional","affiliation":[{"name":"Division of Nephrology and Hypertension, Mayo Clinic , Rochester, MN ,","place":["United States"]}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[2026,8,25]]},"reference":[{"key":"2026082508464973000_aajag165-B1","author":"Mehta","year":"2025"},{"key":"2026082508464973000_aajag165-B2","doi-asserted-by":"publisher","first-page":"171","DOI":"10.1038\/s41581-021-00510-7","article-title":"Nephron overload as a therapeutic target to maximize kidney lifespan","volume":"18","author":"Luyckx","year":"2022","journal-title":"Nat Rev Nephrol"},{"key":"2026082508464973000_aajag165-B3","doi-asserted-by":"publisher","first-page":"917","DOI":"10.1093\/ndt\/gfae234","article-title":"Stenosis of the glomerulotubular neck in progressive chronic kidney disease","volume":"40","author":"Cohen","year":"2025","journal-title":"Nephrol Dial Transplant"},{"key":"2026082508464973000_aajag165-B4","doi-asserted-by":"publisher","first-page":"567","DOI":"10.1016\/S0022-2143(97)90011-1","article-title":"Stenosis of the tubular neck: a possible mechanism for progressive renal failure","volume":"129","author":"Cohen","year":"1997","journal-title":"J Lab Clin Med"},{"key":"2026082508464973000_aajag165-B5","doi-asserted-by":"publisher","first-page":"409","DOI":"10.1097\/HP.0000000000000935","article-title":"Radiation nephropathy in a nonhuman primate model of partial-body irradiation with minimal bone marrow sparing-part 2: histopathology, mediators, and mechanisms","volume":"116","author":"Parker","year":"2019","journal-title":"Health Phys"},{"key":"2026082508464973000_aajag165-B6","author":"Cohen","year":"2024"},{"key":"2026082508464973000_aajag165-B7","doi-asserted-by":"publisher","first-page":"14","DOI":"10.1002\/path.1085","article-title":"Glomerulo-tubular junction stenosis as a factor contributing to glomerular obsolescence in IgA nephropathy","volume":"197","author":"Sato","year":"2002","journal-title":"J Pathol"},{"key":"2026082508464973000_aajag165-B8","first-page":"155","article-title":"Renal microdissection studies in congenital nephrotic syndrome. 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