{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,23]],"date-time":"2026-10-23T11:41:16Z","timestamp":1792755676132,"version":"4.5.0"},"reference-count":30,"publisher":"Oxford University Press (OUP)","license":[{"start":{"date-parts":[[2026,8,25]],"date-time":"2026-08-25T00:00:00Z","timestamp":1787616000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/pages\/standard-publication-reuse-rights"}],"funder":[{"DOI":"10.13039\/501100001807","name":"S\u00e3o Paulo Research Foundation","doi-asserted-by":"publisher","award":["2023\/16119-9"],"award-info":[{"award-number":["2023\/16119-9"]}],"id":[{"id":"10.13039\/501100001807","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Patients on peritoneal dialysis (PD) are at risk of reduced muscle strength and mass. The clinical usefulness of a muscle quality index (MQI), which integrates muscle quantity and function, remains unclear on PD. We evaluated the association between MQI, clinical, nutritional, and physical function parameters on PD.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>Study involving adult patients initiating PD. MQI was calculated as handgrip strength divided by absolute appendicular muscle mass; where higher ratio indicates better muscle quality. Association analyses with MQI were performed with age, sex, albumin, bicarbonate, glycated hemoglobin (HbA1c), interleukin-6, leptin, C-reactive protein, body mass index, body fat percentage, protein equivalent of nitrogen appearance (PNA), phase angle, gait speed, sit-to-stand, and Short Physical Performance Battery (SPPB).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>47 patients (58 \u00b1 15 years; 50% male) were included. Absolute appendicular muscle mass was 20 \u00b1 6.5\u2005kg, handgrip strength 22 [16\u201330] kg, and MQI 1.2 \u00b1 0.4\u2005kgf\/kg. MQI was significantly correlated with age (r = \u22120.550), HbA1c (r = \u22120.450), interleukin-6 (r = \u22120.415), gait speed (r = 0.617), phase angle (r = 0.647), SPPB (r = 0.481), and PNA (g\/day) (r = 0.319). In linear regression models adjusted for age and sex, HbA1c (\u03b2 = \u22120.383; 95% CI, \u22120.132 to \u22120.033, R2 = 0.414), phase angle (\u03b2 = 0.520; 95% CI, 0.90 to 0.304, R2 = 0.446), and gait speed (\u03b2 = 0.448; 95% CI, 0.174 to 1.048, R2 = 0.417) remained associated with MQI (P &amp;lt; .01).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>Patients initiating PD with higher age and HbA1c had lower MQI, while those with higher phase angle and gait speed had higher MQI. These results highlight the role of age, glycemic control, nutritional factors, and physical function in determining muscle quality, aggregating MQI as clinically useful in patients on PD.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1093\/joneph\/aajag231","type":"journal-article","created":{"date-parts":[[2026,8,22]],"date-time":"2026-08-22T11:45:08Z","timestamp":1787399108000},"source":"Crossref","is-referenced-by-count":0,"title":["Muscle quality index in patients on peritoneal dialysis: association with clinical and nutritional factors"],"prefix":"10.1093","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-6602-3625","authenticated-orcid":false,"given":"Maryanne Zilli Canedo","family":"Silva","sequence":"first","affiliation":[{"name":"Internal Medicine Department, Botucatu Medical School, S\u00e3o Paulo State University, UNESP , Botucatu 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Louren\u00e7o","family":"Costa","sequence":"additional","affiliation":[{"name":"Internal Medicine Department, Botucatu Medical School, S\u00e3o Paulo State University, UNESP , Botucatu ,","place":["Brazil"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4979-4836","authenticated-orcid":false,"given":"Pasqual","family":"Barretti","sequence":"additional","affiliation":[{"name":"Internal Medicine Department, Botucatu Medical School, S\u00e3o Paulo State University, UNESP , Botucatu ,","place":["Brazil"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0093-9515","authenticated-orcid":false,"given":"Jacqueline Costa Teixeira","family":"Caramori","sequence":"additional","affiliation":[{"name":"Internal Medicine Department, Botucatu Medical School, S\u00e3o Paulo State University, UNESP , Botucatu 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