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The Electronic Surviving Cancer Competently Intervention Program (eSCCIP) is a psychosocial eHealth intervention for caregivers, developed using an iterative, user-centered process.<\/jats:p><\/jats:sec><jats:sec><jats:title>Method<\/jats:title><jats:p>eSCCIP was tested in a single-arm pilot trial at Nemours Children\u2019s Hospital, Delaware (NCT05333601). The primary outcomes were intervention acceptability and feasibility, assessed via enrollment and retention targets, and item-level acceptability ratings. Enrollment and retention targets of 45% were set based on previous work, and an item-level acceptability threshold of 80% was set. A secondary exploratory analysis was conducted examining acute distress, anxiety, symptoms of post-traumatic stress, and family functioning.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>44 caregivers enrolled in the study and 31 completed. The intervention was rated favorably by completers, with over 80% of the sample selecting \u201cmostly true\u201d or \u201cvery true\u201d for all items of the eSCCIP Evaluation Questionnaire, which was used to assess acceptability and feasibility. Enrollment and retention rates were 54% and 70%, respectively. Exploratory psychosocial outcomes showed statistically significant decreases from pre-intervention to post-intervention for overall symptoms of post-traumatic stress disorder (PTSD), cluster D symptoms of PTSD (negative mood and cognitions), and anxiety. Small-moderate effect sizes were observed for all psychosocial outcomes of interest.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>eSCCIP is an acceptable and feasible intervention for caregivers. Results are promising regarding reductions in symptoms of post-traumatic stress and anxiety.<\/jats:p><\/jats:sec>","DOI":"10.1093\/jpepsy\/jsac082","type":"journal-article","created":{"date-parts":[[2022,10,28]],"date-time":"2022-10-28T08:43:08Z","timestamp":1666946588000},"page":"216-227","source":"Crossref","is-referenced-by-count":6,"title":["Acceptability and Feasibility of eSCCIP: Results From a Pilot Study of the Electronic Surviving Cancer Competently Intervention Program"],"prefix":"10.1093","volume":"48","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-0811-4961","authenticated-orcid":false,"given":"Kimberly S","family":"Canter","sequence":"first","affiliation":[{"name":"Nemours Center for Healthcare Delivery Science, Nemours Children\u2019s Health , Wilmington, DE, USA"},{"name":"Department of Pediatrics, Thomas Jefferson University , Philadelphia, PA, 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