{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,29]],"date-time":"2026-04-29T23:46:04Z","timestamp":1777506364339,"version":"3.51.4"},"reference-count":91,"publisher":"Oxford University Press (OUP)","issue":"6","license":[{"start":{"date-parts":[[2023,5,9]],"date-time":"2023-05-09T00:00:00Z","timestamp":1683590400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/pages\/standard-publication-reuse-rights"}],"funder":[{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","award":["NIH-DA4806"],"award-info":[{"award-number":["NIH-DA4806"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2023,7,5]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:sec>\n                  <jats:title>Objective<\/jats:title>\n                  <jats:p>The objective of this study is to investigate the effects of maternal perinatal depression symptoms and infant treatment status for neonatal abstinence syndrome (NAS) on maternal perceptions of infant regulatory behavior at 6 weeks of age.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Methods<\/jats:title>\n                  <jats:p>Mothers and their infants (N\u2009=\u2009106; 53 dyads) were recruited from a rural, White cohort in Northeast Maine. Mothers in medication-assisted treatment (methadone) and their infants (n\u2009=\u200935 dyads) were divided based on the infant\u2019s NAS pharmacological treatment (n\u2009=\u200920, NAS+ group; n\u2009=\u200915, NAS\u2212 group) and compared with a demographically similar, nonexposed comparison group (n\u2009=\u200918 dyads; COMP group). At 6 weeks postpartum, mothers reported their depression symptoms Beck Depression Inventory\u20142nd Edition) and infant regulatory behaviors [Mother and Baby Scales (MABS)]. Infant neurobehavior was assessed during the same visit using the Neonatal Network Neurobehavioral Scale (NNNS).<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Results<\/jats:title>\n                  <jats:p>Mothers in the NAS+ group showed significantly higher depression scores than the COMP group (p &amp;lt; .05) while the NAS\u2212 group did not. Across the sample, mothers with higher depression scores reported higher infant \u201cunsettled-irregularity\u201d MABS scores, regardless of group status. Agreement between maternal reports of infant regulatory behaviors and observer-assessed NNNS summary scares was poor in both the NAS+ and COMP groups.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Conclusions<\/jats:title>\n                  <jats:p>Postpartum women in opioid recovery with infants requiring pharmacological intervention for NAS are more at risk for depression which may adversely influence their perceptions of their infants\u2019 regulatory profiles. Unique, targeted attachment interventions may be needed for this population.<\/jats:p>\n               <\/jats:sec>","DOI":"10.1093\/jpepsy\/jsad023","type":"journal-article","created":{"date-parts":[[2023,5,11]],"date-time":"2023-05-11T03:07:46Z","timestamp":1683774466000},"page":"583-592","source":"Crossref","is-referenced-by-count":3,"title":["Effect of Neonatal Abstinence Syndrome Treatment Status and Maternal Depressive Symptomatology on Maternal Reports of Infant Behaviors"],"prefix":"10.1093","volume":"48","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-7325-6272","authenticated-orcid":false,"given":"Nicole A","family":"Heller","sequence":"first","affiliation":[{"name":"Department of Psychology, Siena College , USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Beth A","family":"Logan","sequence":"additional","affiliation":[{"name":"Department of Psychiatry and Behavioral Sciences, Boston Children\u2019s Hospital , USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hira","family":"Shrestha","sequence":"additional","affiliation":[{"name":"Department of Medical Oncology, Dana-Farber Cancer Institute , USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Deborah G","family":"Morrison","sequence":"additional","affiliation":[{"name":"Department of Psychiatry, University of Florida , USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Marie J","family":"Hayes","sequence":"additional","affiliation":[{"name":"Department of Psychology and Graduate School of Biomedical Sciences and Engineering, University of Maine , USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"286","published-online":{"date-parts":[[2023,5,9]]},"reference":[{"key":"2023070515060015300_jsad023-B1","doi-asserted-by":"crossref","first-page":"40","DOI":"10.1016\/j.jsat.2014.12.002","article-title":"Treating tobacco use disorder in pregnant women in medication-assisted 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