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For participants with CF, disease characteristics were collected from the Canadian Cystic Fibrosis Registry. Linear regression models were used to determine differences between groups and to examine associations between sleep and mental health outcomes.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Eighty-six participants, 45 with CF (median age\u2009=\u200919 years, IQR\u2009=\u20096 years, 51.1% female, 82.2% on elexacaftor\/tezacaftor\/ivacaftor, ETI) and 41 healthy comparator participants (median age\u2009=\u200916 years, IQR\u2009=\u20094 years, 53.7% female) participated. No significant differences were found between groups in actigraphically measured sleep, self-reported sleep, or anxiety or depression symptoms. In participants with CF, poorer self-reported sleep quality was significantly associated with greater anxiety (p &amp;lt; .001) and depression symptoms (p &amp;lt; .001), but actigraphically measured sleep was not.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>AYA with CF had comparable sleep, anxiety, and depression outcomes as their healthy peers. Only self-reported sleep had a significant relationship with mental health symptoms. These findings stress the importance of concurrent assessment of sleep and mental health in the clinical setting and may inform future longitudinal research. Better understanding relationships between sleep and mental health in AYA with CF could have a significant impact on well-being and quality of life.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1093\/jpepsy\/jsaf103","type":"journal-article","created":{"date-parts":[[2025,11,15]],"date-time":"2025-11-15T19:57:04Z","timestamp":1763236624000},"page":"144-154","source":"Crossref","is-referenced-by-count":0,"title":["Associations between actigraphic and self-reported sleep and mental health in adolescents and young adults with cystic fibrosis"],"prefix":"10.1093","volume":"51","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-1937-6561","authenticated-orcid":false,"given":"Jordana","family":"McMurray","sequence":"first","affiliation":[{"name":"Lawrence Bloomberg Faculty of Nursing, University of Toronto , Toronto, 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