{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,28]],"date-time":"2026-09-28T18:42:47Z","timestamp":1790620967215,"version":"4.1.0"},"reference-count":45,"publisher":"Oxford University Press (OUP)","issue":"4","license":[{"start":{"date-parts":[[2025,12,26]],"date-time":"2025-12-26T00:00:00Z","timestamp":1766707200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/pages\/standard-publication-reuse-rights"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2026,4,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>Functional constipation is common in youth and negatively impacts quality of life. It is also linked to increased behavioral and emotional symptoms. While the impact of mental health problems on individual and family well-being is known, the combined association of youth behavioral\/emotional symptoms and constipation severity on family quality of life remains unclear. This study examined the relationship between these factors and constipation-related family quality of life.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>Participants were 231 children and adolescents (ages 2\u201318\u2009years; M\u2009=\u20097.62, SD\u2009=\u20093.41; 50.6% female; 63.2% white) seen for an initial visit in a pediatric multidisciplinary functional constipation clinic. Families completed questionnaires assessing constipation severity (bowel movement frequency, accidents, abdominal pain, withholding), behavioral\/emotional symptoms (Pediatric Symptom Checklist), and constipation-related health-related quality of life (Parental Opinions of Pediatric Constipation [POOPC]). Hierarchical linear regression was used to analyze the data.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Greater frequency of bowel accidents, greater withholding behaviors, and higher Pediatric Symptom Checklist total scores were each significantly and independently associated with higher POOPC scores (lower health-related quality of life). Together, these factors accounted for 37% of the variance in POOPC scores.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>In youth with functional constipation, bowel accidents, withholding, and parent-reported behavioral\/emotional symptoms are significant predictors of poorer constipation-related family quality of life, highlighting the importance of addressing both medical and behavioral aspects in this population.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1093\/jpepsy\/jsaf111","type":"journal-article","created":{"date-parts":[[2025,12,10]],"date-time":"2025-12-10T13:10:05Z","timestamp":1765372205000},"page":"368-374","source":"Crossref","is-referenced-by-count":1,"title":["Association between youth constipation, emotional\/behavioral symptoms, and family quality of life"],"prefix":"10.1093","volume":"51","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-5236-4533","authenticated-orcid":false,"given":"Erika","family":"Chiappini","sequence":"first","affiliation":[{"name":", Johns Hopkins University Department of Psychiatry and Behavioral Sciences , Baltimore, MD,","place":["United States"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Julia","family":"Modell","sequence":"additional","affiliation":[{"name":", Johns Hopkins University Department of Psychiatry and Behavioral Sciences , Baltimore, MD,","place":["United States"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Seoyeon","family":"Yoo","sequence":"additional","affiliation":[{"name":", Johns Hopkins University Department of Psychiatry and Behavioral Sciences , Baltimore, MD,","place":["United States"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lisa","family":"Santo Domingo","sequence":"additional","affiliation":[{"name":"The Johns Hopkins Hospital Division of Pediatric Gastroenterology, Hepatology and Nutrition, , Baltimore, MD,","place":["United States"]}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[2025,12,26]]},"reference":[{"key":"2026042203513967300_jsaf111-B98457664","doi-asserted-by":"publisher","first-page":"19","DOI":"10.1111\/j.1365-2214.2006.00591.x","article-title":"The psychosocial well-being of children with chronic disease, their parents and siblings: An overview of the research evidence base","volume":"32","author":"Barlow","year":"2006","journal-title":"Child: Care, Health and Development"},{"key":"2026042203513967300_jsaf111-B1","doi-asserted-by":"publisher","first-page":"448","DOI":"10.1097\/00005176-200411000-00002","article-title":"Childhood constipation: Is there new light in the tunnel?","volume":"39","author":"Benninga","year":"2004","journal-title":"Journal of Pediatric Gastroenterology and 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