{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,19]],"date-time":"2026-10-19T19:43:56Z","timestamp":1792439036152,"version":"4.5.0"},"reference-count":44,"publisher":"Oxford University Press (OUP)","issue":"10","license":[{"start":{"date-parts":[[2026,7,22]],"date-time":"2026-07-22T00:00:00Z","timestamp":1784678400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/pages\/standard-publication-reuse-rights"}],"funder":[{"name":"Society of Pediatric Psychology Drotar-Crawford Postdoctoral Fellowship Research Grant"},{"name":"CHOP Bridge to Faculty Program"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2026,10,1]]},"abstract":"Abstract<\/jats:title>\n \n Objective<\/jats:title>\n The transition from pediatric to adult medical care is associated with increased symptoms of anxiety, depression, and experiences with disease stigma for adolescents and young adults (AYA) with sickle cell disease (SCD). Community-informed conceptual frameworks suggest that caregiver communication could play an important role in enhancing AYA well-being during this critical period; yet this association has yet to be empirically investigated in this population. This study examined the influence of caregiver\u2013AYA communication on psychosocial outcomes among AYA with SCD.<\/jats:p>\n <\/jats:sec>\n \n Methods<\/jats:title>\n AYA with SCD ages 16\u201325 were enrolled in a prospective, 3-month study. Participants completed baseline (T1) and follow-up surveys 3\u2009months later (T2). Measures included the Parent-Adolescent Communication Scale, PROMIS Anxiety and Depression short forms, Measure of Sickle Cell Stigma, and Sickle Cell Self-Efficacy Scale. Cross-sectional and prospective bivariate and multivariate associations were investigated.<\/jats:p>\n <\/jats:sec>\n \n Results<\/jats:title>\n Bivariate correlations showed that open caregiver\u2013AYA communication at T1 was cross-sectionally associated with lower anxiety (r\u2009=\u2009\u2212.35, p\u2009=\u2009.016), and prospectively associated with lower anxiety (r\u2009=\u2009\u2212.31, p\u2009=\u2009.047), depression (r\u2009=\u2009\u2212.31, p\u2009=\u2009.045), total stigma (r\u2009=\u2009\u2212.36, p\u2009=\u2009.016) expected discrimination stigma (r\u2009=\u2009\u2212.30, p\u2009=\u2009.048), and internalized stigma (r\u2009=\u2009 .40, p\u2009=\u2009.008). Communication at T1 remained negatively associated with total stigma (\u03b2 = \u2212.21, p\u2009=\u2009\u2212.038), internalized stigma (\u03b2\u2009=\u2009\u2212.24, p\u2009=\u2009.044) and expected discrimination stigma (\u03b2 = \u2212.28, p\u2009=\u2009.030) at T2 when controlling for age, gender, and baseline psychosocial factors.<\/jats:p>\n <\/jats:sec>\n \n Conclusion<\/jats:title>\n AYA who reported open caregiver communication at baseline reported significantly fewer symptoms of anxiety, depression, and stigma 3\u2009months later. Thus, improving caregiver\u2013AYA communication may improve AYA psychosocial functioning, which could lead to improved SCD-related care and transition.<\/jats:p>\n <\/jats:sec>","DOI":"10.1093\/jpepsy\/jsag049","type":"journal-article","created":{"date-parts":[[2026,7,22]],"date-time":"2026-07-22T13:42:00Z","timestamp":1784727720000},"page":"850-857","source":"Crossref","is-referenced-by-count":0,"title":["Caregiver communication and psychosocial outcomes among adolescents and young adults with sickle cell disease"],"prefix":"10.1093","volume":"51","author":[{"ORCID":"https:\/\/orcid.org\/0009-0003-2962-7608","authenticated-orcid":false,"given":"Margaret Mary","family":"Burke","sequence":"first","affiliation":[{"name":"Division of Hematology, Children\u2019s Hospital of Philadelphia , Philadelphia, PA,","place":["United States"]},{"name":"Division of Oncology, Children\u2019s Hospital of Philadelphia , Philadelphia, PA,","place":["United States"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6656-7745","authenticated-orcid":false,"given":"Lori E","family":"Crosby","sequence":"additional","affiliation":[{"name":"Department of Pediatrics, Cincinnati Children\u2019s Hospital and Medical Center , Cincinnati, OH,","place":["United States"]},{"name":"Division of Behavioral Medicine & Clinical Psychology, Cincinnati Children\u2019s Hospital Medical Center , Cincinnati, OH,","place":["United States"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alexis A","family":"Thompson","sequence":"additional","affiliation":[{"name":"Division of Hematology, Children\u2019s Hospital of Philadelphia , Philadelphia, PA,","place":["United States"]},{"name":"Department of Pediatrics, University of Pennsylvania Perelman School of Medicine , Philadelphia, PA,","place":["United States"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lisa A","family":"Schwartz","sequence":"additional","affiliation":[{"name":"Division of Oncology, Children\u2019s Hospital of Philadelphia , Philadelphia, PA,","place":["United States"]},{"name":"Department of Pediatrics, University of Pennsylvania Perelman School of Medicine , Philadelphia, PA,","place":["United States"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5012-9425","authenticated-orcid":false,"given":"Kemar V","family":"Prussien","sequence":"additional","affiliation":[{"name":"Division of Hematology, Children\u2019s Hospital of Philadelphia , Philadelphia, PA,","place":["United States"]},{"name":"Department of Psychiatry, University of Pennsylvania Perelman School of Medicine , Philadelphia, PA,","place":["United 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